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Compound heterozygous mutations in IL10RA combined with a complement factor properdin mutation in infantile-onset inflammatory bowel disease.

Jung ES, Petersen BS, Mayr G, Cheon JH, Kang Y, Lee SJ, Che X, Kim WH, Kim S, Schreiber S, Franke A, Koh H.

Eur J Gastroenterol Hepatol. 2018 Sep 7. doi: 10.1097/MEG.0000000000001247. [Epub ahead of print]


Acoustic Reconstruction for Photothermal Imaging.

Burgholzer P, Stockner G, Mayr G.

Bioengineering (Basel). 2018 Aug 29;5(3). pii: E70. doi: 10.3390/bioengineering5030070.


Pelvis morphology suggests that early Mesozoic birds were too heavy to contact incubate their eggs.

Charles Deeming D, Mayr G.

J Evol Biol. 2018 May;31(5):701-709. doi: 10.1111/jeb.13256. Epub 2018 Mar 26.


A Paleocene penguin from New Zealand substantiates multiple origins of gigantism in fossil Sphenisciformes.

Mayr G, Scofield RP, De Pietri VL, Tennyson AJD.

Nat Commun. 2017 Dec 12;8(1):1927. doi: 10.1038/s41467-017-01959-6.


Size and number of the hypoglossal nerve foramina in the avian skull and their potential neuroanatomical significance.

Mayr G.

J Morphol. 2018 Feb;279(2):274-285. doi: 10.1002/jmor.20770. Epub 2017 Oct 31.


Preservation of uropygial gland lipids in a 48-million-year-old bird.

O'Reilly S, Summons R, Mayr G, Vinther J.

Proc Biol Sci. 2017 Oct 25;284(1865). pii: 20171050. doi: 10.1098/rspb.2017.1050.


Late Pleistocene songbirds of Liang Bua (Flores, Indonesia); the first fossil passerine fauna described from Wallacea.

Meijer HJM, Awe Due R, Sutikna T, Saptomo W, Jatmiko, Wasisto S, Tocheri MW, Mayr G.

PeerJ. 2017 Aug 17;5:e3676. doi: 10.7717/peerj.3676. eCollection 2017.


Spatio-temporal precipitation climatology over complex terrain using a censored additive regression model.

Stauffer R, Mayr GJ, Messner JW, Umlauf N, Zeileis A.

Int J Climatol. 2017 Jun 15;37(7):3264-3275. doi: 10.1002/joc.4913. Epub 2016 Nov 9.


A new fossil from the mid-Paleocene of New Zealand reveals an unexpected diversity of world's oldest penguins.

Mayr G, De Pietri VL, Paul Scofield R.

Naturwissenschaften. 2017 Apr;104(3-4):9. doi: 10.1007/s00114-017-1441-0. Epub 2017 Feb 23.


3D Camouflage in an Ornithischian Dinosaur.

Vinther J, Nicholls R, Lautenschlager S, Pittman M, Kaye TG, Rayfield E, Mayr G, Cuthill IC.

Curr Biol. 2016 Sep 26;26(18):2456-2462. doi: 10.1016/j.cub.2016.06.065. Epub 2016 Sep 15.


Targeted Resequencing and Functional Testing Identifies Low-Frequency Missense Variants in the Gene Encoding GARP as Significant Contributors to Atopic Dermatitis Risk.

Manz J, Rodríguez E, ElSharawy A, Oesau EM, Petersen BS, Baurecht H, Mayr G, Weber S, Harder J, Reischl E, Schwarz A, Novak N, Franke A, Weidinger S.

J Invest Dermatol. 2016 Dec;136(12):2380-2386. doi: 10.1016/j.jid.2016.07.009. Epub 2016 Jul 21.


The early Eocene birds of the Messel fossil site: a 48 million-year-old bird community adds a temporal perspective to the evolution of tropical avifaunas.

Mayr G.

Biol Rev Camb Philos Soc. 2017 May;92(2):1174-1188. doi: 10.1111/brv.12274. Epub 2016 Apr 8. Review.


Multiple efficacy studies of an adenovirus-vectored foot-and-mouth disease virus serotype A24 subunit vaccine in cattle using homologous challenge.

Schutta C, Barrera J, Pisano M, Zsak L, Grubman MJ, Mayr GA, Moraes MP, Kamicker BJ, Brake DA, Ettyreddy D, Brough DE, Butman BT, Neilan JG.

Vaccine. 2016 Jun 8;34(27):3214-3220. doi: 10.1016/j.vaccine.2015.12.018. Epub 2015 Dec 18.


Review of the 2012 Epizootic Hemorrhagic Disease Outbreak in Domestic Ruminants in the United States.

Stevens G, McCluskey B, King A, O'Hearn E, Mayr G.

PLoS One. 2015 Aug 5;10(8):e0133359. doi: 10.1371/journal.pone.0133359. eCollection 2015.


The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells.

Schröder D, Tödter K, Gonzalez B, Franco-Echevarría E, Rohaly G, Blecher C, Lin HY, Mayr GW, Windhorst S.

Biochem Pharmacol. 2015 Jul 15;96(2):143-50. doi: 10.1016/j.bcp.2015.05.004. Epub 2015 May 15.


On the origin of feathers.

Mayr G.

Science. 2014 Dec 19;346(6216):1466. doi: 10.1126/science.346.6216.1466-b. No abstract available.


Eocene fossil is earliest evidence of flower-visiting by birds.

Mayr G, Wilde V.

Biol Lett. 2014 May;10(5):20140223. doi: 10.1098/rsbl.2014.0223.


Discovery of InsP6-kinases as InsP6-dephosphorylating enzymes provides a new mechanism of cytosolic InsP6 degradation driven by the cellular ATP/ADP ratio.

Wundenberg T, Grabinski N, Lin H, Mayr GW.

Biochem J. 2014 Aug 15;462(1):173-84. doi: 10.1042/BJ20130992.


XIAP variants in male Crohn's disease.

Zeissig Y, Petersen BS, Milutinovic S, Bosse E, Mayr G, Peuker K, Hartwig J, Keller A, Kohl M, Laass MW, Billmann-Born S, Brandau H, Feller AC, Röcken C, Schrappe M, Rosenstiel P, Reed JC, Schreiber S, Franke A, Zeissig S.

Gut. 2015 Jan;64(1):66-76. doi: 10.1136/gutjnl-2013-306520. Epub 2014 Feb 26.


Earliest and first Northern Hemispheric hoatzin fossils substantiate Old World origin of a "Neotropic endemic".

Mayr G, De Pietri VL.

Naturwissenschaften. 2014 Feb;101(2):143-8. doi: 10.1007/s00114-014-1144-8. Epub 2014 Jan 18.


Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate.

Helmis C, Blechner C, Lin H, Schweizer M, Mayr GW, Nielsen P, Windhorst S.

Biosci Rep. 2013 Oct 22;33(5). pii: e00075. doi: 10.1042/BSR20130079.


Can ovarian follicles fossilize?

Mayr G, Manegold A.

Nature. 2013 Jul 11;499(7457):E1. doi: 10.1038/nature12367. No abstract available.


Autophagy receptor CALCOCO2/NDP52 takes center stage in Crohn disease.

Till A, Lipinski S, Ellinghaus D, Mayr G, Subramani S, Rosenstiel P, Franke A.

Autophagy. 2013 Aug;9(8):1256-7. doi: 10.4161/auto.25483. Epub 2013 Jun 28.


Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.

Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Stade B, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Häsler R, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V, Vogel U, Kupcinskas L, Kayser M, Krawczak M, Nikolaus S, Weersma RK, Ponsioen CY, Sans M, Wijmenga C, Strachan DP, McArdle WL, Vermeire S, Rutgeerts P, Sanderson JD, Mathew CG, Vatn MH, Wang J, Nöthen MM, Duerr RH, Büning C, Brand S, Glas J, Winkelmann J, Illig T, Latiano A, Annese V, Halfvarson J, D'Amato M, Daly MJ, Nothnagel M, Karlsen TH, Subramani S, Rosenstiel P, Schreiber S, Parkes M, Franke A.

Gastroenterology. 2013 Aug;145(2):339-47. doi: 10.1053/j.gastro.2013.04.040. Epub 2013 Apr 25.


Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S, Winkelmann J, Mitrovic M, Braun F, Ponsioen CY, Croucher PJ, Sterneck M, Teufel A, Mason AL, Saarela J, Leppa V, Dorfman R, Alvaro D, Floreani A, Onengut-Gumuscu S, Rich SS, Thompson WK, Schork AJ, Næss S, Thomsen I, Mayr G, König IR, Hveem K, Cleynen I, Gutierrez-Achury J, Ricaño-Ponce I, van Heel D, Björnsson E, Sandford RN, Durie PR, Melum E, Vatn MH, Silverberg MS, Duerr RH, Padyukov L, Brand S, Sans M, Annese V, Achkar JP, Boberg KM, Marschall HU, Chazouillères O, Bowlus CL, Wijmenga C, Schrumpf E, Vermeire S, Albrecht M; UK-PSCSC Consortium, Rioux JD, Alexander G, Bergquist A, Cho J, Schreiber S, Manns MP, Färkkilä M, Dale AM, Chapman RW, Lazaridis KN; International PSC Study Group, Franke A, Anderson CA, Karlsen TH; International IBD Genetics Consortium.

Nat Genet. 2013 Jun;45(6):670-5. doi: 10.1038/ng.2616. Epub 2013 Apr 21.


Identification and characterization of mimotopes of classical swine fever virus E2 glycoprotein using specific anti-E2 monoclonal antibodies.

Batonick M, Loeffen W, Metwally SA, Mayr GA.

Virus Res. 2013 Jul;175(1):12-9. doi: 10.1016/j.virusres.2013.03.016. Epub 2013 Apr 11.


A non-catalytic role for inositol 1,3,4,5,6-pentakisphosphate 2-kinase in the synthesis of ribosomal RNA.

Brehm MA, Wundenberg T, Williams J, Mayr GW, Shears SB.

J Cell Sci. 2013 Jan 15;126(Pt 2):437-44. doi: 10.1242/jcs.110031. Epub 2012 Nov 30.


Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation.

Windhorst S, Lin H, Blechner C, Fanick W, Brandt L, Brehm MA, Mayr GW.

Biochem J. 2013 Feb 15;450(1):115-25. doi: 10.1042/BJ20121524.


A Plasmodium multi-domain protein possesses multiple inositol phosphate kinase activities.

Stritzke C, Nalaskowski MM, Fanick W, Lin H, Mayr GW.

Mol Biochem Parasitol. 2012 Dec;186(2):134-8. doi: 10.1016/j.molbiopara.2012.10.005. Epub 2012 Nov 1.


Synthesis and biological actions of diphosphoinositol phosphates (inositol pyrophosphates), regulators of cell homeostasis.

Wundenberg T, Mayr GW.

Biol Chem. 2012 Sep;393(9):979-98. doi: 10.1515/hsz-2012-0133. Review.


Nucleocytoplasmic shuttling of human inositol phosphate multikinase is influenced by CK2 phosphorylation.

Meyer R, Nalaskowski MM, Ehm P, Schröder C, Naj X, Brehm MA, Mayr GW.

Biol Chem. 2012 Mar;393(3):149-60. doi: 10.1515/hsz-2011-0209.


A toolkit for graded expression of green fluorescent protein fusion proteins in mammalian cells.

Nalaskowski MM, Ehm P, Giehler S, Mayr GW.

Anal Biochem. 2012 Sep 1;428(1):24-7. doi: 10.1016/j.ab.2012.06.001. Epub 2012 Jun 12.


Diagnosis of Porcine teschovirus encephalomyelitis in the Republic of Haiti.

Deng MY, Millien M, Jacques-Simon R, Flanagan JK, Bracht AJ, Carrillo C, Barrette RW, Fabian A, Mohamed F, Moran K, Rowland J, Swenson SL, Jenkins-Moore M, Koster L, Thomsen BV, Mayr G, Pyburn D, Morales P, Shaw J, Burrage T, White W, McIntosh MT, Metwally S.

J Vet Diagn Invest. 2012 Jul;24(4):671-8. doi: 10.1177/1040638712445769. Epub 2012 May 17.


Human regulatory T cells rapidly suppress T cell receptor-induced Ca(2+), NF-κB, and NFAT signaling in conventional T cells.

Schmidt A, Oberle N, Weiss EM, Vobis D, Frischbutter S, Baumgrass R, Falk CS, Haag M, Brügger B, Lin H, Mayr GW, Reichardt P, Gunzer M, Suri-Payer E, Krammer PH.

Sci Signal. 2011 Dec 20;4(204):ra90. doi: 10.1126/scisignal.2002179.


Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients.

Windhorst S, Minge D, Bähring R, Hüser S, Schob C, Blechner C, Lin HY, Mayr GW, Kindler S.

Cell Signal. 2012 Mar;24(3):750-7. doi: 10.1016/j.cellsig.2011.11.010. Epub 2011 Nov 18.


Analysis of clinical samples for early detection of classical swine fever during infection with low, moderate, and highly virulent strains in relation to the onset of clinical signs.

Donahue BC, Petrowski HM, Melkonian K, Ward GB, Mayr GA, Metwally S.

J Virol Methods. 2012 Jan;179(1):108-15. doi: 10.1016/j.jviromet.2011.10.008. Epub 2011 Oct 20.


A novel Entamoeba histolytica inositol phosphate kinase catalyzes the formation of 5PP-Ins(1,2,3,4,6)P(5).

Löser B, Nalaskowski MM, Fanick W, Lin H, Tannich E, Mayr GW.

Mol Biochem Parasitol. 2012 Jan;181(1):49-52. doi: 10.1016/j.molbiopara.2011.09.008. Epub 2011 Sep 29.


Out of Africa: Fossils shed light on the origin of the hoatzin, an iconic Neotropic bird.

Mayr G, Alvarenga H, Mourer-Chauviré C.

Naturwissenschaften. 2011 Nov;98(11):961-6. doi: 10.1007/s00114-011-0849-1. Epub 2011 Oct 1.


The inositol 5-phosphatase SHIP1 is a nucleo-cytoplasmic shuttling protein and enzymatically active in cell nuclei.

Nalaskowski MM, Metzner A, Brehm MA, Labiadh S, Brauer H, Grabinski N, Mayr GW, Jücker M.

Cell Signal. 2012 Mar;24(3):621-8. doi: 10.1016/j.cellsig.2011.07.012. Epub 2011 Aug 16.


Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells.

Windhorst S, Kalinina T, Schmid K, Blechner C, Kriebitzsch N, Hinsch R, Chang L, Herich L, Schumacher U, Mayr GW.

Int J Cancer. 2011 Sep 15;129(6):1300-9. doi: 10.1002/ijc.25782. Epub 2011 Jan 6.


Structure collisions between interacting proteins.

Emig D, Sander O, Mayr G, Albrecht M.

PLoS One. 2011;6(6):e19581. doi: 10.1371/journal.pone.0019581. Epub 2011 Jun 2.


Expression Regulation of the Metastasis-Promoting Protein InsP3-Kinase-A in Tumor Cells.

Chang L, Schwarzenbach H, Meyer-Staeckling S, Brandt B, Mayr GW, Weitzel JM, Windhorst S.

Mol Cancer Res. 2011 Apr;9(4):497-506. doi: 10.1158/1541-7786.MCR-10-0556. Epub 2011 Apr 1.


Foot-and-mouth disease in feral swine: susceptibility and transmission.

Mohamed F, Swafford S, Petrowski H, Bracht A, Schmit B, Fabian A, Pacheco JM, Hartwig E, Berninger M, Carrillo C, Mayr G, Moran K, Kavanaugh D, Leibrecht H, White W, Metwally S.

Transbound Emerg Dis. 2011 Aug;58(4):358-71. doi: 10.1111/j.1865-1682.2011.01213.x. Epub 2011 Mar 21.


Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice.

Blüml S, Bonelli M, Niederreiter B, Puchner A, Mayr G, Hayer S, Koenders MI, van den Berg WB, Smolen J, Redlich K.

Arthritis Rheum. 2011 May;63(5):1281-8. doi: 10.1002/art.30281.


Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.

Nalaskowski MM, Fliegert R, Ernst O, Brehm MA, Fanick W, Windhorst S, Lin H, Giehler S, Hein J, Lin YN, Mayr GW.

J Biol Chem. 2011 Feb 11;286(6):4500-10. doi: 10.1074/jbc.M110.173062. Epub 2010 Dec 9.


Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.

Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, Raelson JV, Belouchi M, Fournier H, Reinhard C, Ding J, Li Y, Tejasvi T, Gudjonsson J, Stoll SW, Voorhees JJ, Lambert S, Weidinger S, Eberlein B, Kunz M, Rahman P, Gladman DD, Gieger C, Wichmann HE, Karlsen TH, Mayr G, Albrecht M, Kabelitz D, Mrowietz U, Abecasis GR, Elder JT, Schreiber S, Weichenthal M, Franke A.

Nat Genet. 2010 Nov;42(11):991-5. doi: 10.1038/ng.689. Epub 2010 Oct 17.


Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles.

Brunner S, Hurni S, Streckeisen P, Mayr G, Albrecht M, Yahiaoui N, Keller B.

Plant J. 2010 Nov;64(3):433-45. doi: 10.1111/j.1365-313X.2010.04342.x. Epub 2010 Sep 28.


Synthesis and nonradioactive micro-analysis of diphosphoinositol phosphates by HPLC with postcolumn complexometry.

Lin H, Lindner K, Mayr GW.

Methods Mol Biol. 2010;645:103-22. doi: 10.1007/978-1-60327-175-2_7.


Pathogenicity and molecular characterization of emerging porcine reproductive and respiratory syndrome virus in Vietnam in 2007.

Metwally S, Mohamed F, Faaberg K, Burrage T, Prarat M, Moran K, Bracht A, Mayr G, Berninger M, Koster L, To TL, Nguyen VL, Reising M, Landgraf J, Cox L, Lubroth J, Carrillo C.

Transbound Emerg Dis. 2010 Oct;57(5):315-29. doi: 10.1111/j.1865-1682.2010.01152.x. Epub 2010 Jul 9.


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