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Items: 1 to 50 of 109

1.

Human cytomegalovirus-specific T-cell receptor engineered for high affinity and soluble expression using mammalian cell display.

Wagner EK, Qerqez AN, Stevens CA, Nguyen AW, Delidakis G, Maynard JA.

J Biol Chem. 2019 Apr 12;294(15):5790-5804. doi: 10.1074/jbc.RA118.007187. Epub 2019 Feb 22.

2.

Humanised monoclonal antibodies neutralise pertussis toxin by receptor blockade and reduced retrograde trafficking.

Acquaye-Seedah E, Huang Y, Sutherland JN, DiVenere AM, Maynard JA.

Cell Microbiol. 2018 Dec;20(12):e12948. doi: 10.1111/cmi.12948. Epub 2018 Sep 23.

3.

Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice.

Boehm DT, Hall JM, Wong TY, DiVenere AM, Sen-Kilic E, Bevere JR, Bradford SD, Blackwood CB, Elkins CM, DeRoos KA, Gray MC, Cooper CG, Varney ME, Maynard JA, Hewlett EL, Barbier M, Damron FH.

Infect Immun. 2018 Sep 21;86(10). pii: e00857-17. doi: 10.1128/IAI.00857-17. Print 2018 Oct.

4.

Recent Advances Incorporating Superparamagnetic Nanoparticles into Immunoassays.

Ha Y, Ko S, Kim I, Huang Y, Mohanty K, Huh C, Maynard JA.

ACS Appl Nano Mater. 2018 Feb 23;1(2):512-521. doi: 10.1021/acsanm.7b00025. Epub 2018 Jan 31.

5.

Engineering therapeutic antibodies to combat infectious diseases.

Wagner EK, Maynard JA.

Curr Opin Chem Eng. 2018 Mar;19:131-141. doi: 10.1016/j.coche.2018.01.007. Epub 2018 Mar 7.

6.

Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization.

Acquaye-Seedah E, Reczek EE, Russell HH, DiVenere AM, Sandman SO, Collins JH, Stein CA, Whitehead TA, Maynard JA.

Infect Immun. 2018 May 22;86(6). pii: e00004-18. doi: 10.1128/IAI.00004-18. Print 2018 Jun.

7.

Apparent diffusion coefficient for molecular subtyping of non-gadolinium-enhancing WHO grade II/III glioma: volumetric segmentation versus two-dimensional region of interest analysis.

Thust SC, Hassanein S, Bisdas S, Rees JH, Hyare H, Maynard JA, Brandner S, Tur C, Jäger HR, Yousry TA, Mancini L.

Eur Radiol. 2018 Sep;28(9):3779-3788. doi: 10.1007/s00330-018-5351-0. Epub 2018 Mar 23.

8.

Identification of high affinity HER2 binding antibodies using CHO Fab surface display.

Nguyen AW, Le KC, Maynard JA.

Protein Eng Des Sel. 2018 Mar 1;31(3):91-101. doi: 10.1093/protein/gzy004.

9.

Charge Shielding Prevents Aggregation of Supercharged GFP Variants at High Protein Concentration.

Laber JR, Dear BJ, Martins ML, Jackson DE, DiVenere A, Gollihar JD, Ellington AD, Truskett TM, Johnston KP, Maynard JA.

Mol Pharm. 2017 Oct 2;14(10):3269-3280. doi: 10.1021/acs.molpharmaceut.7b00322. Epub 2017 Sep 18.

10.

De novo design of antibody complementarity determining regions binding a FLAG tetra-peptide.

Entzminger KC, Hyun JM, Pantazes RJ, Patterson-Orazem AC, Qerqez AN, Frye ZP, Hughes RA, Ellington AD, Lieberman RL, Maranas CD, Maynard JA.

Sci Rep. 2017 Aug 31;7(1):10295. doi: 10.1038/s41598-017-10737-9.

11.

Fire coral clones demonstrate phenotypic plasticity among reef habitats.

Dubé CE, Boissin E, Maynard JA, Planes S.

Mol Ecol. 2017 Aug;26(15):3860-3869. doi: 10.1111/mec.14165. Epub 2017 May 30.

PMID:
28475270
12.

Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.

Wang X, Stapleton JA, Klesmith JR, Hewlett EL, Whitehead TA, Maynard JA.

Biochemistry. 2017 Mar 7;56(9):1324-1336. doi: 10.1021/acs.biochem.6b01163. Epub 2017 Feb 23.

13.

Warming Trends and Bleaching Stress of the World's Coral Reefs 1985-2012.

Heron SF, Maynard JA, van Hooidonk R, Eakin CM.

Sci Rep. 2016 Dec 6;6:38402. doi: 10.1038/srep38402.

14.

First genealogy for a wild marine fish population reveals multigenerational philopatry.

Salles OC, Pujol B, Maynard JA, Almany GR, Berumen ML, Jones GP, Saenz-Agudelo P, Srinivasan M, Thorrold SR, Planes S.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13245-13250. Epub 2016 Oct 31.

15.

Prior exposure to Bordetella species as an exclusion criterion in the baboon model of pertussis.

Nguyen AW, Wagner EK, Posada L, Liu X, Connelly S, Papin JF, Wolf RF, Kaleko M, Maynard JA.

J Vet Med Sci. 2017 Jan 20;79(1):60-64. doi: 10.1292/jvms.16-0427. Epub 2016 Sep 26.

16.

Synergistic Neutralization of Pertussis Toxin by a Bispecific Antibody In Vitro and In Vivo.

Wagner EK, Wang X, Bui A, Maynard JA.

Clin Vaccine Immunol. 2016 Nov 4;23(11):851-862. Print 2016 Nov.

17.

Overfishing and nutrient pollution interact with temperature to disrupt coral reefs down to microbial scales.

Zaneveld JR, Burkepile DE, Shantz AA, Pritchard CE, McMinds R, Payet JP, Welsh R, Correa AM, Lemoine NP, Rosales S, Fuchs C, Maynard JA, Thurber RV.

Nat Commun. 2016 Jun 7;7:11833. doi: 10.1038/ncomms11833.

18.

A robust operational model for predicting where tropical cyclone waves damage coral reefs.

Puotinen M, Maynard JA, Beeden R, Radford B, Williams GJ.

Sci Rep. 2016 May 17;6:26009. doi: 10.1038/srep26009.

19.

Coral mass spawning predicted by rapid seasonal rise in ocean temperature.

Keith SA, Maynard JA, Edwards AJ, Guest JR, Bauman AG, van Hooidonk R, Heron SF, Berumen ML, Bouwmeester J, Piromvaragorn S, Rahbek C, Baird AH.

Proc Biol Sci. 2016 May 11;283(1830). pii: 20160011. doi: 10.1098/rspb.2016.0011.

20.

Inclusion of an RGD Motif Alters Invasin Integrin-Binding Affinity and Specificity.

Khan TA, Wang X, Maynard JA.

Biochemistry. 2016 Apr 12;55(14):2078-90. doi: 10.1021/acs.biochem.5b01243. Epub 2016 Mar 25.

PMID:
27015583
21.

Bioavailability of Fullerene under Environmentally Relevant Conditions: Effects of Humic Acid and Fetal Bovine Serum on Accumulation in Lipid Bilayers and Cellular Uptake.

Ha Y, Wang X, Liljestrand HM, Maynard JA, Katz LE.

Environ Sci Technol. 2016 Jul 5;50(13):6717-27. doi: 10.1021/acs.est.5b04964. Epub 2016 Mar 21.

PMID:
26943027
22.

A cocktail of humanized anti-pertussis toxin antibodies limits disease in murine and baboon models of whooping cough.

Nguyen AW, Wagner EK, Laber JR, Goodfield LL, Smallridge WE, Harvill ET, Papin JF, Wolf RF, Padlan EA, Bristol A, Kaleko M, Maynard JA.

Sci Transl Med. 2015 Dec 2;7(316):316ra195. doi: 10.1126/scitranslmed.aad0966.

23.

Coral reef fish populations can persist without immigration.

Salles OC, Maynard JA, Joannides M, Barbu CM, Saenz-Agudelo P, Almany GR, Berumen ML, Thorrold SR, Jones GP, Planes S.

Proc Biol Sci. 2015 Nov 22;282(1819). pii: 20151311. doi: 10.1098/rspb.2015.1311.

24.

The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.

Wang X, Gray MC, Hewlett EL, Maynard JA.

J Biol Chem. 2015 Sep 18;290(38):23025. doi: 10.1074/jbc.A114.585281. No abstract available.

25.

Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing.

Kowalsky CA, Faber MS, Nath A, Dann HE, Kelly VW, Liu L, Shanker P, Wagner EK, Maynard JA, Chan C, Whitehead TA.

J Biol Chem. 2015 Oct 30;290(44):26457-70. doi: 10.1074/jbc.M115.676635. Epub 2015 Aug 20.

26.

Increased Fab thermoresistance via VH-targeted directed evolution.

Entzminger KC, Johnson JL, Hyun J, Lieberman RL, Maynard JA.

Protein Eng Des Sel. 2015 Oct;28(10):365-77. doi: 10.1093/protein/gzv037. Epub 2015 Aug 16.

27.

Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization.

Johnson JL, Entzminger KC, Hyun J, Kalyoncu S, Heaner DP Jr, Morales IA, Sheppard A, Gumbart JC, Maynard JA, Lieberman RL.

Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):896-906. doi: 10.1107/S1399004715001856. Epub 2015 Mar 27.

28.

Downscaled projections of Caribbean coral bleaching that can inform conservation planning.

van Hooidonk R, Maynard JA, Liu Y, Lee SK.

Glob Chang Biol. 2015 Sep;21(9):3389-401. doi: 10.1111/gcb.12901. Epub 2015 Apr 1.

29.
30.

Blacktip reef sharks, Carcharhinus melanopterus, have high genetic structure and varying demographic histories in their Indo-Pacific range.

Vignaud TM, Mourier J, Maynard JA, Leblois R, Spaet J, Clua E, Neglia V, Planes S.

Mol Ecol. 2014 Nov;23(21):5193-207. doi: 10.1111/mec.12936. Epub 2014 Oct 13.

PMID:
25251515
31.

Operationalizing resilience for adaptive coral reef management under global environmental change.

Anthony KR, Marshall PA, Abdulla A, Beeden R, Bergh C, Black R, Eakin CM, Game ET, Gooch M, Graham NA, Green A, Heron SF, van Hooidonk R, Knowland C, Mangubhai S, Marshall N, Maynard JA, McGinnity P, McLeod E, Mumby PJ, Nyström M, Obura D, Oliver J, Possingham HP, Pressey RL, Rowlands GP, Tamelander J, Wachenfeld D, Wear S.

Glob Chang Biol. 2015 Jan;21(1):48-61. doi: 10.1111/gcb.12700. Epub 2014 Sep 5. Review.

32.

Rapid survey protocol that provides dynamic information on reef condition to managers of the Great Barrier Reef.

Beeden RJ, Turner MA, Dryden J, Merida F, Goudkamp K, Malone C, Marshall PA, Birtles A, Maynard JA.

Environ Monit Assess. 2014 Dec;186(12):8527-40. doi: 10.1007/s10661-014-4022-0. Epub 2014 Sep 3.

PMID:
25179944
33.

Genetic structure of populations of whale sharks among ocean basins and evidence for their historic rise and recent decline.

Vignaud TM, Maynard JA, Leblois R, Meekan MG, Vázquez-Juárez R, Ramírez-Macías D, Pierce SJ, Rowat D, Berumen ML, Beeravolu C, Baksay S, Planes S.

Mol Ecol. 2014 May;23(10):2590-601. doi: 10.1111/mec.12754.

PMID:
24750370
34.

Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments.

Kalyoncu S, Hyun J, Pai JC, Johnson JL, Entzminger K, Jain A, Heaner DP Jr, Morales IA, Truskett TM, Maynard JA, Lieberman RL.

Proteins. 2014 Sep;82(9):1884-95. doi: 10.1002/prot.24542. Epub 2014 Mar 24.

35.

Immunotherapeutic Approaches To Prevent Cytomegalovirus-Mediated Disease.

Seedah EA, Frye ZP, Maynard JA.

Microbiol Spectr. 2014 Feb;2(1):AID-0009-2013. doi: 10.1128/microbiolspec.AID-0009-13. Review.

PMID:
26082112
36.

Back to the future: recombinant polyclonal antibody therapeutics.

Wang XZ, Coljee VW, Maynard JA.

Curr Opin Chem Eng. 2013 Nov;2(4):405-415.

37.

Opposite latitudinal gradients in projected ocean acidification and bleaching impacts on coral reefs.

van Hooidonk R, Maynard JA, Manzello D, Planes S.

Glob Chang Biol. 2014 Jan;20(1):103-12. doi: 10.1111/gcb.12394. Epub 2013 Oct 21.

PMID:
24151155
38.

Changes in bleaching susceptibility among corals subject to ocean warming and recurrent bleaching in Moorea, French Polynesia.

Pratchett MS, McCowan D, Maynard JA, Heron SF.

PLoS One. 2013 Jul 29;8(7):e70443. doi: 10.1371/journal.pone.0070443. Print 2013.

39.

In vivo whole animal fluorescence imaging of a microparticle-based oral vaccine containing (CuInSe(x)S(2-x))/ZnS core/shell quantum dots.

Panthani MG, Khan TA, Reid DK, Hellebusch DJ, Rasch MR, Maynard JA, Korgel BA.

Nano Lett. 2013 Sep 11;13(9):4294-8. doi: 10.1021/nl402054w. Epub 2013 Aug 9.

40.

Frozen-state storage stability of a monoclonal antibody: aggregation is impacted by freezing rate and solute distribution.

Miller MA, Rodrigues MA, Glass MA, Singh SK, Johnston KP, Maynard JA.

J Pharm Sci. 2013 Apr;102(4):1194-208. doi: 10.1002/jps.23473. Epub 2013 Feb 8.

PMID:
23400717
41.

Flanking residues are central to DO11.10 T cell hybridoma stimulation by ovalbumin 323-339.

Roy BM, Zhukov DV, Maynard JA.

PLoS One. 2012;7(10):e47585. doi: 10.1371/journal.pone.0047585. Epub 2012 Oct 23.

42.

Prioritizing key resilience indicators to support coral reef management in a changing climate.

McClanahan TR, Donner SD, Maynard JA, MacNeil MA, Graham NA, Maina J, Baker AC, Alemu I JB, Beger M, Campbell SJ, Darling ES, Eakin CM, Heron SF, Jupiter SD, Lundquist CJ, McLeod E, Mumby PJ, Paddack MJ, Selig ER, van Woesik R.

PLoS One. 2012;7(8):e42884. doi: 10.1371/journal.pone.0042884. Epub 2012 Aug 29.

43.

Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in vivo bioavailability.

Miller MA, Khan TA, Kaczorowski KJ, Wilson BK, Dinin AK, Borwankar AU, Rodrigues MA, Truskett TM, Johnston KP, Maynard JA.

J Pharm Sci. 2012 Oct;101(10):3763-78. doi: 10.1002/jps.23256. Epub 2012 Jul 6.

44.

The Skp chaperone helps fold soluble proteins in vitro by inhibiting aggregation.

Entzminger KC, Chang C, Myhre RO, McCallum KC, Maynard JA.

Biochemistry. 2012 Jun 19;51(24):4822-34. doi: 10.1021/bi300412y. Epub 2012 Jun 8.

45.

Contrasting patterns of coral bleaching susceptibility in 2010 suggest an adaptive response to thermal stress.

Guest JR, Baird AH, Maynard JA, Muttaqin E, Edwards AJ, Campbell SJ, Yewdall K, Affendi YA, Chou LM.

PLoS One. 2012;7(3):e33353. doi: 10.1371/journal.pone.0033353. Epub 2012 Mar 9.

46.

Concentrated dispersions of equilibrium protein nanoclusters that reversibly dissociate into active monomers.

Johnston KP, Maynard JA, Truskett TM, Borwankar AU, Miller MA, Wilson BK, Dinin AK, Khan TA, Kaczorowski KJ.

ACS Nano. 2012 Feb 28;6(2):1357-69. doi: 10.1021/nn204166z. Epub 2012 Jan 30.

PMID:
22260218
47.

Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics.

Im H, Sutherland JN, Maynard JA, Oh SH.

Anal Chem. 2012 Feb 21;84(4):1941-7. doi: 10.1021/ac300070t. Epub 2012 Feb 7.

48.

Restriction enzyme-free construction of random gene mutagenesis libraries in Escherichia coli.

Pai JC, Entzminger KC, Maynard JA.

Anal Biochem. 2012 Feb 15;421(2):640-8. doi: 10.1016/j.ab.2011.11.009. Epub 2011 Nov 18.

49.

A framework for responding to coral disease outbreaks that facilitates adaptive management.

Beeden R, Maynard JA, Marshall PA, Heron SF, Willis BL.

Environ Manage. 2012 Jan;49(1):1-13. doi: 10.1007/s00267-011-9770-9. Epub 2011 Nov 1.

PMID:
22042407
50.

Crystallization chaperone strategies for membrane proteins.

Lieberman RL, Culver JA, Entzminger KC, Pai JC, Maynard JA.

Methods. 2011 Dec;55(4):293-302. doi: 10.1016/j.ymeth.2011.08.004. Epub 2011 Aug 11. Review.

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