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Items: 1 to 50 of 612

1.

High-resolution 3D visualization of nanomedicine distribution in tumors.

Moss JI, Barjat H, Emmas SA, Strittmatter N, Maynard J, Goodwin RJA, Storm G, Lammers T, Puri S, Ashford MB, Barry ST.

Theranostics. 2020 Jan 1;10(2):880-897. doi: 10.7150/thno.37178. eCollection 2020.

2.

The Opportunities and Use of Imaging to Measure Target Engagement.

Maynard J, Hart P.

SLAS Discov. 2020 Feb;25(2):127-136. doi: 10.1177/2472555219897270. Epub 2019 Dec 29.

PMID:
31885303
3.

Prey-size plastics are invading larval fish nurseries.

Gove JM, Whitney JL, McManus MA, Lecky J, Carvalho FC, Lynch JM, Li J, Neubauer P, Smith KA, Phipps JE, Kobayashi DR, Balagso KB, Contreras EA, Manuel ME, Merrifield MA, Polovina JJ, Asner GP, Maynard JA, Williams GJ.

Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24143-24149. doi: 10.1073/pnas.1907496116. Epub 2019 Nov 11.

4.

Engineering Antibodies on the Surface of CHO Cells.

Nguyen AW, Le K, Maynard JA.

Methods Mol Biol. 2020;2070:397-422. doi: 10.1007/978-1-4939-9853-1_22.

PMID:
31625108
5.

IL8 Expression Is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer.

Maynard JP, Ertunc O, Kulac I, Baena-Del Valle JA, De Marzo AM, Sfanos KS.

Mol Cancer Res. 2020 Jan;18(1):153-165. doi: 10.1158/1541-7786.MCR-19-0595. Epub 2019 Oct 11.

PMID:
31604846
6.

Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis.

Porter CM, Haffner MC, Kulac I, Maynard JP, Baena-Del Valle JA, Isaacs WB, Yegnasubramanian S, De Marzo AM, Sfanos KS.

Am J Pathol. 2019 Nov;189(11):2311-2322. doi: 10.1016/j.ajpath.2019.07.016. Epub 2019 Sep 6.

PMID:
31499027
7.

A paleosol record of the evolution of Cr redox cycling and evidence for an increase in atmospheric oxygen during the Neoproterozoic.

Colwyn DA, Sheldon ND, Maynard JB, Gaines R, Hofmann A, Wang X, Gueguen B, Asael D, Reinhard CT, Planavsky NJ.

Geobiology. 2019 Nov;17(6):579-593. doi: 10.1111/gbi.12360. Epub 2019 Aug 22.

PMID:
31436043
8.

APC transcription studies and molecular diagnosis of familial adenomatous polyposis.

Short E, Thomas LE, Davies A, Bolton A, Maynard J, Giles P, Mort M, Consoli C, Egner I, Jundi H, Sampson JR.

Eur J Hum Genet. 2020 Jan;28(1):118-121. doi: 10.1038/s41431-019-0486-2. Epub 2019 Aug 5.

PMID:
31383941
9.

Lessons learned from the development of a hidradenitis suppurativa xenograft mouse model.

Quartey QQ, Miller RJ, Pinsker BL, Okoh UJ, Shipman WD, George BA, Nwizu CC, Barnes LA, Kerns ML, Caffrey JA, Aliu O, Brown ID, Succaria F, Maynard JP, Herbert AS, Kang S, Miller LS, Okoye GA, Byrd AS.

Clin Exp Dermatol. 2019 Jul 19. doi: 10.1111/ced.14054. [Epub ahead of print]

PMID:
31322280
10.

Isometric-based test improves EMG-threshold determination in boys vs. men.

Woods S, Dotan R, Jenicek N, Maynard J, Gabriel D, Tokuno C, Falk B.

Eur J Appl Physiol. 2019 Sep;119(9):1971-1979. doi: 10.1007/s00421-019-04185-8. Epub 2019 Jul 4.

PMID:
31273453
11.

Skin Intrinsic Fluorescence and Selected Measures of Visual Function and aging in Older Adults.

Klein BEK, Lee KE, Maynard JD, Johnson CA, Danforth L, Klein R.

Ophthalmic Epidemiol. 2019 Aug;26(4):264-269. doi: 10.1080/09286586.2019.1604977. Epub 2019 Apr 27.

PMID:
31030599
12.

Human cytomegalovirus-specific T-cell receptor engineered for high affinity and soluble expression using mammalian cell display.

Wagner EK, Qerqez AN, Stevens CA, Nguyen AW, Delidakis G, Maynard JA.

J Biol Chem. 2019 Apr 12;294(15):5790-5804. doi: 10.1074/jbc.RA118.007187. Epub 2019 Feb 22.

13.

The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation.

Liu B, Salgado OC, Singh S, Hippen KL, Maynard JC, Burlingame AL, Ball LE, Blazar BR, Farrar MA, Hogquist KA, Ruan HB.

Nat Commun. 2019 Jan 21;10(1):354. doi: 10.1038/s41467-019-08300-3.

14.

The future of resilience-based management in coral reef ecosystems.

Mcleod E, Anthony KRN, Mumby PJ, Maynard J, Beeden R, Graham NAJ, Heron SF, Hoegh-Guldberg O, Jupiter S, MacGowan P, Mangubhai S, Marshall N, Marshall PA, McClanahan TR, Mcleod K, Nyström M, Obura D, Parker B, Possingham HP, Salm RV, Tamelander J.

J Environ Manage. 2019 Mar 1;233:291-301. doi: 10.1016/j.jenvman.2018.11.034. Epub 2018 Dec 21. Review.

15.

Transvaginal fast-scanning optical-resolution photoacoustic endoscopy.

Qu Y, Li C, Shi J, Chen R, Xu S, Rafsanjani H, Maslov K, Krigman H, Garvey L, Hu P, Zhao P, Meyers K, Diveley E, Pizzella S, Muench L, Punyamurthy N, Goldstein N, Onwumere O, Alisio M, Meyenburg K, Maynard J, Helm K, Slaughter J, Barber S, Burger T, Kramer C, Chubiz J, Anderson M, McCarthy R, England SK, Macones GA, Zhou Q, Shung KK, Zou J, Stout MJ, Tuuli M, Wang LV.

J Biomed Opt. 2018 Dec;23(12):1-4. doi: 10.1117/1.JBO.23.12.121617.

16.

In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra.

Qu Y, Hu P, Shi J, Maslov K, Zhao P, Li C, Ma J, Garcia-Uribe A, Meyers K, Diveley E, Pizzella S, Muench L, Punyamurthy N, Goldstein N, Onwumere O, Alisio M, Meyenburg K, Maynard J, Helm K, Altieri E, Slaughter J, Barber S, Burger T, Kramer C, Chubiz J, Anderson M, McCarthy R, England SK, Macones GA, Stout MJ, Tuuli M, Wang LV.

J Biomed Opt. 2018 Dec;23(12):1-6. doi: 10.1117/1.JBO.23.12.121621.

17.

Dosage Considerations for Canakinumab in Children With Periodic Fever Syndromes.

Zhuang L, Chen J, Yu J, Marathe A, Sahajwalla C, Borigini M, Maynard J, Burckart GJ, Wang Y.

Clin Pharmacol Ther. 2019 Sep;106(3):557-567. doi: 10.1002/cpt.1302. Epub 2019 Jan 28. Review.

PMID:
30447083
18.

A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth.

Yu SH, Maynard JP, Vaghasia AM, De Marzo AM, Drake CG, Sfanos KS.

Prostate. 2019 Feb;79(2):215-222. doi: 10.1002/pros.23726. Epub 2018 Oct 21.

PMID:
30345534
19.

Humanised monoclonal antibodies neutralise pertussis toxin by receptor blockade and reduced retrograde trafficking.

Acquaye-Seedah E, Huang Y, Sutherland JN, DiVenere AM, Maynard JA.

Cell Microbiol. 2018 Dec;20(12):e12948. doi: 10.1111/cmi.12948. Epub 2018 Sep 23.

20.

Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy.

Madi A, Fisher D, Maughan TS, Colley JP, Meade AM, Maynard J, Humphreys V, Wasan H, Adams RA, Idziaszczyk S, Harris R, Kaplan RS, Cheadle JP.

Eur J Cancer. 2018 Oct;102:31-39. doi: 10.1016/j.ejca.2018.07.009. Epub 2018 Aug 13.

PMID:
30114658
21.

Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors.

Lynch JT, Polanska UM, Hancox U, Delpuech O, Maynard J, Trigwell C, Eberlein C, Lenaghan C, Polanski R, Avivar-Valderas A, Cumberbatch M, Klinowska T, Critchlow SE, Cruzalegui F, Barry ST.

Mol Cancer Ther. 2018 Nov;17(11):2309-2319. doi: 10.1158/1535-7163.MCT-18-0183. Epub 2018 Aug 10.

22.

Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice.

Boehm DT, Hall JM, Wong TY, DiVenere AM, Sen-Kilic E, Bevere JR, Bradford SD, Blackwood CB, Elkins CM, DeRoos KA, Gray MC, Cooper CG, Varney ME, Maynard JA, Hewlett EL, Barbier M, Damron FH.

Infect Immun. 2018 Sep 21;86(10). pii: e00857-17. doi: 10.1128/IAI.00857-17. Print 2018 Oct.

23.

Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN.

Kim S, Maynard JC, Strickland A, Burlingame AL, Milbrandt J.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):8019-8024. doi: 10.1073/pnas.1805538115. Epub 2018 Jul 16.

24.

Recent Advances Incorporating Superparamagnetic Nanoparticles into Immunoassays.

Ha Y, Ko S, Kim I, Huang Y, Mohanty K, Huh C, Maynard JA.

ACS Appl Nano Mater. 2018 Feb 23;1(2):512-521. doi: 10.1021/acsanm.7b00025. Epub 2018 Jan 31.

25.

Engineering therapeutic antibodies to combat infectious diseases.

Wagner EK, Maynard JA.

Curr Opin Chem Eng. 2018 Mar;19:131-141. doi: 10.1016/j.coche.2018.01.007. Epub 2018 Mar 7.

26.

Managing Sports-related Concussions From Time of Injury Through Return to Play.

Shirley E, Hudspeth LJ, Maynard JR.

J Am Acad Orthop Surg. 2018 Jul 1;26(13):e279-e286. doi: 10.5435/JAAOS-D-16-00684. Review.

PMID:
29864036
27.

Collagen deposition in chronic hidradenitis suppurativa: potential role for CD163+ macrophages.

Byrd AS, Kerns ML, Williams DW, Zarif JC, Rosenberg AZ, Delsante M, Liu H, Dillen CA, Maynard JP, Caffrey JA, Sacks JM, Milner SM, Aliu O, Broderick KP, Lew LS, Miller LS, Kang S, Okoye GA.

Br J Dermatol. 2018 Sep;179(3):792-794. doi: 10.1111/bjd.16600. Epub 2018 Jun 29. No abstract available.

28.

Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization.

Acquaye-Seedah E, Reczek EE, Russell HH, DiVenere AM, Sandman SO, Collins JH, Stein CA, Whitehead TA, Maynard JA.

Infect Immun. 2018 May 22;86(6). pii: e00004-18. doi: 10.1128/IAI.00004-18. Print 2018 Jun.

29.

Sickle Cell Disease is Associated With Elevated Levels of Skin Advanced Glycation Endproducts.

Kashyap L, Alsaheel A, Ranck M, Gardner R, Maynard J, Chalew SA.

J Pediatr Hematol Oncol. 2018 May;40(4):285-289. doi: 10.1097/MPH.0000000000001128.

PMID:
29578924
30.

Apparent diffusion coefficient for molecular subtyping of non-gadolinium-enhancing WHO grade II/III glioma: volumetric segmentation versus two-dimensional region of interest analysis.

Thust SC, Hassanein S, Bisdas S, Rees JH, Hyare H, Maynard JA, Brandner S, Tur C, Jäger HR, Yousry TA, Mancini L.

Eur Radiol. 2018 Sep;28(9):3779-3788. doi: 10.1007/s00330-018-5351-0. Epub 2018 Mar 23.

31.

Identification of high affinity HER2 binding antibodies using CHO Fab surface display.

Nguyen AW, Le KC, Maynard JA.

Protein Eng Des Sel. 2018 Mar 1;31(3):91-101. doi: 10.1093/protein/gzy004.

32.

When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions.

Bradbury ARM, Trinklein ND, Thie H, Wilkinson IC, Tandon AK, Anderson S, Bladen CL, Jones B, Aldred SF, Bestagno M, Burrone O, Maynard J, Ferrara F, Trimmer JS, Görnemann J, Glanville J, Wolf P, Frenzel A, Wong J, Koh XY, Eng HY, Lane D, Lefranc MP, Clark M, Dübel S.

MAbs. 2018 May/Jun;10(4):539-546. doi: 10.1080/19420862.2018.1445456. Epub 2018 Mar 29.

33.

Skin Intrinsic Fluorescence and Age-Related Macular Degeneration: The Beaver Dam Eye Study.

Klein R, Lee KE, Maynard JD, Meuer SM, Gangnon RE, Klein BEK.

Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6328-6333. doi: 10.1167/iovs.17-22382.

34.

Considerations in the Care of Athletes With Attention Deficit Hyperactivity Disorder.

Pujalte GGA, Maynard JR, Thurston MJ, Taylor WC 3rd, Chauhan M.

Clin J Sport Med. 2019 May;29(3):245-256. doi: 10.1097/JSM.0000000000000508. Review.

PMID:
29189334
35.

Charge Shielding Prevents Aggregation of Supercharged GFP Variants at High Protein Concentration.

Laber JR, Dear BJ, Martins ML, Jackson DE, DiVenere A, Gollihar JD, Ellington AD, Truskett TM, Johnston KP, Maynard JA.

Mol Pharm. 2017 Oct 2;14(10):3269-3280. doi: 10.1021/acs.molpharmaceut.7b00322. Epub 2017 Sep 18.

36.

De novo design of antibody complementarity determining regions binding a FLAG tetra-peptide.

Entzminger KC, Hyun JM, Pantazes RJ, Patterson-Orazem AC, Qerqez AN, Frye ZP, Hughes RA, Ellington AD, Lieberman RL, Maranas CD, Maynard JA.

Sci Rep. 2017 Aug 31;7(1):10295. doi: 10.1038/s41598-017-10737-9.

37.

The use of 18F-Fluoro-deoxy-glucose positron emission tomography (18F-FDG PET) as a non-invasive pharmacodynamic biomarker to determine the minimally pharmacologically active dose of AZD8835, a novel PI3Kα inhibitor.

Maynard J, Emmas SA, Ble FX, Barjat H, Lawrie E, Hancox U, Polanska UM, Pritchard A, Hudson K.

PLoS One. 2017 Aug 14;12(8):e0183048. doi: 10.1371/journal.pone.0183048. eCollection 2017.

38.

Burden and Profile of Somatic Mutation in Duodenal Adenomas from Patients with Familial Adenomatous- and MUTYH-associated Polyposis.

Thomas LE, Hurley JJ, Meuser E, Jose S, Ashelford KE, Mort M, Idziaszczyk S, Maynard J, Brito HL, Harry M, Walters A, Raja M, Walton SJ, Dolwani S, Williams GT, Morgan M, Moorghen M, Clark SK, Sampson JR.

Clin Cancer Res. 2017 Nov 1;23(21):6721-6732. doi: 10.1158/1078-0432.CCR-17-1269. Epub 2017 Aug 8.

39.

Fire coral clones demonstrate phenotypic plasticity among reef habitats.

Dubé CE, Boissin E, Maynard JA, Planes S.

Mol Ecol. 2017 Aug;26(15):3860-3869. doi: 10.1111/mec.14165. Epub 2017 May 30.

PMID:
28475270
40.

Breaks in MODIS time series portend vegetation change: verification using long-term data in an arid grassland ecosystem.

Browning DM, Maynard JJ, Karl JW, Peters DC.

Ecol Appl. 2017 Jul;27(5):1677-1693. doi: 10.1002/eap.1561.

PMID:
28423459
41.

A hyper-temporal remote sensing protocol for high-resolution mapping of ecological sites.

Maynard JJ, Karl JW.

PLoS One. 2017 Apr 17;12(4):e0175201. doi: 10.1371/journal.pone.0175201. eCollection 2017.

42.

Association of Skin Intrinsic Fluorescence with Retinal Microvascular Complications of Long Term Type 1 Diabetes in the Wisconsin Epidemiologic Study of Diabetic Retinopathy.

Klein BEK, Horak KL, Maynard JD, Lee KE, Klein R.

Ophthalmic Epidemiol. 2017 Aug;24(4):211-216. doi: 10.1080/09286586.2016.1269934. Epub 2017 Mar 13.

43.

Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab.

Madi A, Fisher D, Maughan TS, Colley JP, Meade AM, Tejpar S, Van den Bosch B, Maynard J, Humphreys V, Wasan H, Adams RA, Idziaszczyk S, Harris R, Kaplan RS, Cheadle JP.

J Med Genet. 2017 Aug;54(8):567-571. doi: 10.1136/jmedgenet-2016-104317. Epub 2017 Mar 10.

PMID:
28283541
44.

Sex differences in the association of skin advanced glycation endproducts with knee osteoarthritis progression.

Eaton CB, Sayeed M, Ameernaz S, Roberts MB, Maynard JD, Driban JB, McAlindon TE.

Arthritis Res Ther. 2017 Feb 17;19(1):36. doi: 10.1186/s13075-017-1226-z.

45.

Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.

Wang X, Stapleton JA, Klesmith JR, Hewlett EL, Whitehead TA, Maynard JA.

Biochemistry. 2017 Mar 7;56(9):1324-1336. doi: 10.1021/acs.biochem.6b01163. Epub 2017 Feb 23.

46.

Proteomic analysis reveals O-GlcNAc modification on proteins with key regulatory functions in Arabidopsis.

Xu SL, Chalkley RJ, Maynard JC, Wang W, Ni W, Jiang X, Shin K, Cheng L, Savage D, Hühmer AF, Burlingame AL, Wang ZY.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1536-E1543. doi: 10.1073/pnas.1610452114. Epub 2017 Feb 2.

47.

Population expansions dominate demographic histories of endemic and widespread Pacific reef fishes.

Delrieu-Trottin E, Mona S, Maynard J, Neglia V, Veuille M, Planes S.

Sci Rep. 2017 Jan 16;7:40519. doi: 10.1038/srep40519.

48.

Local-scale projections of coral reef futures and implications of the Paris Agreement.

van Hooidonk R, Maynard J, Tamelander J, Gove J, Ahmadia G, Raymundo L, Williams G, Heron SF, Planes S.

Sci Rep. 2016 Dec 21;6:39666. doi: 10.1038/srep39666.

49.

Warming Trends and Bleaching Stress of the World's Coral Reefs 1985-2012.

Heron SF, Maynard JA, van Hooidonk R, Eakin CM.

Sci Rep. 2016 Dec 6;6:38402. doi: 10.1038/srep38402.

50.

Cysteine S-linked N-acetylglucosamine (S-GlcNAcylation), A New Post-translational Modification in Mammals.

Maynard JC, Burlingame AL, Medzihradszky KF.

Mol Cell Proteomics. 2016 Nov;15(11):3405-3411. Epub 2016 Aug 24.

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