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Items: 1 to 50 of 207

1.

Molecular mechanism of setron-mediated inhibition of full-length 5-HT3A receptor.

Basak S, Gicheru Y, Kapoor A, Mayer ML, Filizola M, Chakrapani S.

Nat Commun. 2019 Jul 19;10(1):3225. doi: 10.1038/s41467-019-11142-8.

2.

Structural biology of glutamate receptor ion channels: towards an understanding of mechanism.

Greger IH, Mayer ML.

Curr Opin Struct Biol. 2019 Aug;57:185-195. doi: 10.1016/j.sbi.2019.05.004. Epub 2019 Jun 8. Review.

PMID:
31185364
3.

Sex-Based Differences in Outcomes After Mitral Valve Surgery for Severe Ischemic Mitral Regurgitation: From the Cardiothoracic Surgical Trials Network.

Giustino G, Overbey J, Taylor D, Ailawadi G, Kirkwood K, DeRose J, Gillinov MA, Dagenais F, Mayer ML, Moskowitz A, Bagiella E, Miller M, Grayburn P, Smith PK, Gelijns A, O'Gara P, Acker M, Lala A, Hung J.

JACC Heart Fail. 2019 Jun;7(6):481-490. doi: 10.1016/j.jchf.2019.03.001.

PMID:
31146872
4.

Family matters.

Mayer ML, Jegla T.

Elife. 2018 Dec 28;7. pii: e43815. doi: 10.7554/eLife.43815.

5.

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study.

Gulack BC, Kirkwood KA, Shi W, Smith PK, Alexander JH, Burks SG, Gelijns AC, Thourani VH, Bell D, Greenberg A, Goldfarb SD, Mayer ML, Bowdish ME; Cardiothoracic Surgical Trials Network (CTSN).

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1555-1562.e1. doi: 10.1016/j.jtcvs.2017.10.078. Epub 2017 Dec 6.

6.

A multi-institutional cohort study confirming the risks of Clostridium difficile infection associated with prolonged antibiotic prophylaxis.

Kirkwood KA, Gulack BC, Iribarne A, Bowdish ME, Greco G, Mayer ML, O'Sullivan K, Gelijns AC, Fumakia N, Ghanta RK, Raiten JM, Lala A, Ladowski JS, Blackstone EH, Parides MK, Moskowitz AJ, Horvath KA.

J Thorac Cardiovasc Surg. 2018 Feb;155(2):670-678.e1. doi: 10.1016/j.jtcvs.2017.09.089. Epub 2017 Sep 28.

7.

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.

Zhao H, Lomash S, Chittori S, Glasser C, Mayer ML, Schuck P.

Elife. 2017 Oct 23;6. pii: e32056. doi: 10.7554/eLife.32056.

8.

The Challenge of Interpreting Glutamate-Receptor Ion-Channel Structures.

Mayer ML.

Biophys J. 2017 Nov 21;113(10):2143-2151. doi: 10.1016/j.bpj.2017.07.028. Epub 2017 Aug 24. Review.

9.

Novel Functional Properties of Drosophila CNS Glutamate Receptors.

Li Y, Dharkar P, Han TH, Serpe M, Lee CH, Mayer ML.

Neuron. 2016 Dec 7;92(5):1036-1048. doi: 10.1016/j.neuron.2016.10.058. Epub 2016 Nov 23.

10.

Molecular lock regulates binding of glycine to a primitive NMDA receptor.

Yu A, Alberstein R, Thomas A, Zimmet A, Grey R, Mayer ML, Lau AY.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6786-E6795. Epub 2016 Oct 17.

11.

The structure and function of glutamate receptors: Mg2+ block to X-ray diffraction.

Mayer ML.

Neuropharmacology. 2017 Jan;112(Pt A):4-10. doi: 10.1016/j.neuropharm.2016.04.039. Epub 2016 Apr 27. Review.

12.

Structural basis of kainate subtype glutamate receptor desensitization.

Meyerson JR, Chittori S, Merk A, Rao P, Han TH, Serpe M, Mayer ML, Subramaniam S.

Nature. 2016 Sep 22;537(7621):567-571. doi: 10.1038/nature19352. Epub 2016 Aug 31.

13.

Structural biology of glutamate receptor ion channel complexes.

Mayer ML.

Curr Opin Struct Biol. 2016 Dec;41:119-127. doi: 10.1016/j.sbi.2016.07.002. Epub 2016 Jul 22. Review.

PMID:
27454049
14.

Monochromatic multicomponent fluorescence sedimentation velocity for the study of high-affinity protein interactions.

Zhao H, Fu Y, Glasser C, Andrade Alba EJ, Mayer ML, Patterson G, Schuck P.

Elife. 2016 Jul 20;5. pii: e17812. doi: 10.7554/eLife.17812.

15.

Convenient synthesis of phosphonohydrazines from arylamines.

Kent GT, Blackburn DJ, Gonzalez JR, Mayer ML, Wu W.

Tetrahedron Lett. 2016 Apr 11;57(19):2097-2099.

16.

Rate Control versus Rhythm Control for Atrial Fibrillation after Cardiac Surgery.

Gillinov AM, Bagiella E, Moskowitz AJ, Raiten JM, Groh MA, Bowdish ME, Ailawadi G, Kirkwood KA, Perrault LP, Parides MK, Smith RL 2nd, Kern JA, Dussault G, Hackmann AE, Jeffries NO, Miller MA, Taddei-Peters WC, Rose EA, Weisel RD, Williams DL, Mangusan RF, Argenziano M, Moquete EG, O'Sullivan KL, Pellerin M, Shah KJ, Gammie JS, Mayer ML, Voisine P, Gelijns AC, O'Gara PT, Mack MJ; CTSN.

N Engl J Med. 2016 May 19;374(20):1911-21. doi: 10.1056/NEJMoa1602002. Epub 2016 Apr 4.

17.

Diabetes and the Association of Postoperative Hyperglycemia With Clinical and Economic Outcomes in Cardiac Surgery.

Greco G, Ferket BS, D'Alessandro DA, Shi W, Horvath KA, Rosen A, Welsh S, Bagiella E, Neill AE, Williams DL, Greenberg A, Browndyke JN, Gillinov AM, Mayer ML, Keim-Malpass J, Gupta LS, Hohmann SF, Gelijns AC, O'Gara PT, Moskowitz AJ.

Diabetes Care. 2016 Mar;39(3):408-17. doi: 10.2337/dc15-1817. Epub 2016 Jan 19.

18.

Glycine activated ion channel subunits encoded by ctenophore glutamate receptor genes.

Alberstein R, Grey R, Zimmet A, Simmons DK, Mayer ML.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E6048-57. doi: 10.1073/pnas.1513771112. Epub 2015 Oct 12.

19.

Functional reconstitution of Drosophila melanogaster NMJ glutamate receptors.

Han TH, Dharkar P, Mayer ML, Serpe M.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6182-7. doi: 10.1073/pnas.1500458112. Epub 2015 Apr 27.

20.

Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports.

Meyerson JR, Rao P, Kumar J, Chittori S, Banerjee S, Pierson J, Mayer ML, Subramaniam S.

Sci Rep. 2014 Nov 18;4:7084. doi: 10.1038/srep07084.

21.

Readmissions after cardiac surgery: experience of the National Institutes of Health/Canadian Institutes of Health research cardiothoracic surgical trials network.

Iribarne A, Chang H, Alexander JH, Gillinov AM, Moquete E, Puskas JD, Bagiella E, Acker MA, Mayer ML, Ferguson TB, Burks S, Perrault LP, Welsh S, Johnston KC, Murphy M, DeRose JJ, Neill A, Dobrev E, Baio KT, Taddei-Peters W, Moskowitz AJ, O'Gara PT.

Ann Thorac Surg. 2014 Oct;98(4):1274-80. doi: 10.1016/j.athoracsur.2014.06.059. Epub 2014 Aug 28.

22.

Structural mechanism of glutamate receptor activation and desensitization.

Meyerson JR, Kumar J, Chittori S, Rao P, Pierson J, Bartesaghi A, Mayer ML, Subramaniam S.

Nature. 2014 Oct 16;514(7522):328-34. doi: 10.1038/nature13603. Epub 2014 Aug 3.

23.

Analysis of protein interactions with picomolar binding affinity by fluorescence-detected sedimentation velocity.

Zhao H, Mayer ML, Schuck P.

Anal Chem. 2014 Mar 18;86(6):3181-7. doi: 10.1021/ac500093m. Epub 2014 Mar 5.

24.

Analysis of high affinity self-association by fluorescence optical sedimentation velocity analytical ultracentrifugation of labeled proteins: opportunities and limitations.

Zhao H, Lomash S, Glasser C, Mayer ML, Schuck P.

PLoS One. 2013 Dec 17;8(12):e83439. doi: 10.1371/journal.pone.0083439. eCollection 2013.

25.

INVEX--a web-based tool for integrative visualization of expression data.

Xia J, Lyle NH, Mayer ML, Pena OM, Hancock RE.

Bioinformatics. 2013 Dec 15;29(24):3232-4. doi: 10.1093/bioinformatics/btt562. Epub 2013 Sep 26.

26.

Conformational analysis of NMDA receptor GluN1, GluN2, and GluN3 ligand-binding domains reveals subtype-specific characteristics.

Yao Y, Belcher J, Berger AJ, Mayer ML, Lau AY.

Structure. 2013 Oct 8;21(10):1788-99. doi: 10.1016/j.str.2013.07.011. Epub 2013 Aug 22.

27.

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains.

Zhao H, Berger AJ, Brown PH, Kumar J, Balbo A, May CA, Casillas E Jr, Laue TM, Patterson GH, Mayer ML, Schuck P.

J Gen Physiol. 2013 Jun;141(6):747-9. No abstract available.

28.

INMEX--a web-based tool for integrative meta-analysis of expression data.

Xia J, Fjell CD, Mayer ML, Pena OM, Wishart DS, Hancock RE.

Nucleic Acids Res. 2013 Jul;41(Web Server issue):W63-70. doi: 10.1093/nar/gkt338. Epub 2013 Jun 12.

29.

Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain.

Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, Subramaniam S.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):5921-6. doi: 10.1073/pnas.1217549110. Epub 2013 Mar 25.

30.

Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis, and bronchopulmonary dysplasia.

Ali S, Hirschfeld AF, Mayer ML, Fortuno ES 3rd, Corbett N, Kaplan M, Wang S, Schneiderman J, Fjell CD, Yan J, Akhabir L, Aminuddin F, Marr N, Lacaze-Masmonteil T, Hegele RG, Becker A, Chan-Yeung M, Hancock RE, Kollmann TR, Daley D, Sandford AJ, Lavoie PM, Turvey SE.

J Immunol. 2013 Apr 15;190(8):3949-58. doi: 10.4049/jimmunol.1201015. Epub 2013 Mar 13.

31.

Anions mediate ligand binding in Adineta vaga glutamate receptor ion channels.

Lomash S, Chittori S, Brown P, Mayer ML.

Structure. 2013 Mar 5;21(3):414-25. doi: 10.1016/j.str.2013.01.006. Epub 2013 Feb 21.

32.

Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells.

Mayer ML, Blohmke CJ, Falsafi R, Fjell CD, Madera L, Turvey SE, Hancock RE.

J Immunol. 2013 Feb 1;190(3):1227-38. doi: 10.4049/jimmunol.1201404. Epub 2012 Dec 21.

33.

Zinc potentiates GluK3 glutamate receptor function by stabilizing the ligand binding domain dimer interface.

Veran J, Kumar J, Pinheiro PS, Athané A, Mayer ML, Perrais D, Mulle C.

Neuron. 2012 Nov 8;76(3):565-78. doi: 10.1016/j.neuron.2012.08.027.

34.

Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses.

Blohmke CJ, Mayer ML, Tang AC, Hirschfeld AF, Fjell CD, Sze MA, Falsafi R, Wang S, Hsu K, Chilvers MA, Hogg JC, Hancock RE, Turvey SE.

J Immunol. 2012 Dec 1;189(11):5467-75. doi: 10.4049/jimmunol.1103661. Epub 2012 Oct 26.

35.

Functional insights from glutamate receptor ion channel structures.

Kumar J, Mayer ML.

Annu Rev Physiol. 2013;75:313-37. doi: 10.1146/annurev-physiol-030212-183711. Epub 2012 Sep 4. Review.

36.

Fluxes in "free" and total zinc are essential for progression of intraerythrocytic stages of Plasmodium falciparum.

Marvin RG, Wolford JL, Kidd MJ, Murphy S, Ward J, Que EL, Mayer ML, Penner-Hahn JE, Haldar K, O'Halloran TV.

Chem Biol. 2012 Jun 22;19(6):731-41. doi: 10.1016/j.chembiol.2012.04.013.

37.

Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria.

Achtman AH, Pilat S, Law CW, Lynn DJ, Janot L, Mayer ML, Ma S, Kindrachuk J, Finlay BB, Brinkman FS, Smyth GK, Hancock RE, Schofield L.

Sci Transl Med. 2012 May 23;4(135):135ra64. doi: 10.1126/scitranslmed.3003515.

38.

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains.

Zhao H, Berger AJ, Brown PH, Kumar J, Balbo A, May CA, Casillas E Jr, Laue TM, Patterson GH, Mayer ML, Schuck P.

J Gen Physiol. 2012 May;139(5):371-88. doi: 10.1085/jgp.201210770. Epub 2012 Apr 16. Erratum in: J Gen Physiol. 2013 Jun;141(6):747-9.

39.

Emerging models of glutamate receptor ion channel structure and function.

Mayer ML.

Structure. 2011 Oct 12;19(10):1370-80. doi: 10.1016/j.str.2011.08.009. Review.

40.

Structure and assembly mechanism for heteromeric kainate receptors.

Kumar J, Schuck P, Mayer ML.

Neuron. 2011 Jul 28;71(2):319-31. doi: 10.1016/j.neuron.2011.05.038.

41.

Glutamate receptor ion channels: where do all the calories go?

Mayer ML.

Nat Struct Mol Biol. 2011 Mar;18(3):253-4. doi: 10.1038/nsmb0311-253. No abstract available.

PMID:
21372852
42.

Structure and mechanism of glutamate receptor ion channel assembly, activation and modulation.

Mayer ML.

Curr Opin Neurobiol. 2011 Apr;21(2):283-90. doi: 10.1016/j.conb.2011.02.001. Epub 2011 Feb 23. Review.

43.

The Pseudomonas aeruginosa autoinducer 3O-C12 homoserine lactone provokes hyperinflammatory responses from cystic fibrosis airway epithelial cells.

Mayer ML, Sheridan JA, Blohmke CJ, Turvey SE, Hancock RE.

PLoS One. 2011 Jan 31;6(1):e16246. doi: 10.1371/journal.pone.0016246.

44.

Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains.

Kumar J, Mayer ML.

J Mol Biol. 2010 Dec 10;404(4):680-96. doi: 10.1016/j.jmb.2010.10.006. Epub 2010 Oct 14.

45.

Oxidative stress enhances IL-8 and inhibits CCL20 production from intestinal epithelial cells in response to bacterial flagellin.

Ivison SM, Wang C, Himmel ME, Sheridan J, Delano J, Mayer ML, Yao Y, Kifayet A, Steiner TS.

Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G733-41. doi: 10.1152/ajpgi.00089.2010. Epub 2010 Jul 1.

46.

Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.

Alushin GM, Jane D, Mayer ML.

Neuropharmacology. 2011 Jan;60(1):126-34. doi: 10.1016/j.neuropharm.2010.06.002. Epub 2010 Jun 15.

47.

Accounting for solvent signal offsets in the analysis of interferometric sedimentation velocity data.

Zhao H, Brown PH, Balbo A, Fernández-Alonso Mdel C, Polishchuck N, Chaudhry C, Mayer ML, Ghirlando R, Schuck P.

Macromol Biosci. 2010 Jul 7;10(7):736-45. doi: 10.1002/mabi.200900456.

PMID:
20480511
48.

Cathelicidins link the endocrine and immune systems.

Mayer ML, Hancock RE.

Cell Host Microbe. 2010 Apr 22;7(4):257-9. doi: 10.1016/j.chom.2010.04.002.

49.

Domain organization and function in GluK2 subtype kainate receptors.

Das U, Kumar J, Mayer ML, Plested AJ.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8463-8. doi: 10.1073/pnas.1000838107. Epub 2010 Apr 19.

50.

Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.

Nijnik A, Madera L, Ma S, Waldbrook M, Elliott MR, Easton DM, Mayer ML, Mullaly SC, Kindrachuk J, Jenssen H, Hancock RE.

J Immunol. 2010 Mar 1;184(5):2539-50. doi: 10.4049/jimmunol.0901813. Epub 2010 Jan 27.

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