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Items: 1 to 50 of 102

1.

Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line.

Vorobyev A, Gupta Y, Sezin T, Koga H, Bartsch YC, Belheouane M, Künzel S, Sina C, Schilf P, Körber-Ahrens H, Beltsiou F, Lara Ernst A, Khil'chenko S, Al-Aasam H, Manz RA, Diehl S, Steinhaus M, Jascholt J, Kouki P, Boehncke WH, Mayadas TN, Zillikens D, Sadik CD, Nishi H, Ehlers M, Möller S, Bieber K, Baines JF, Ibrahim SM, Ludwig RJ.

Nat Commun. 2019 Sep 10;10(1):4097. doi: 10.1038/s41467-019-11952-w.

2.

Neutrophils in lupus nephritis.

Nishi H, Mayadas TN.

Curr Opin Rheumatol. 2019 Mar;31(2):193-200. doi: 10.1097/BOR.0000000000000577.

PMID:
30540580
3.

Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment.

Saggu G, Okubo K, Chen Y, Vattepu R, Tsuboi N, Rosetti F, Cullere X, Washburn N, Tahir S, Rosado AM, Holland SM, Anthony RM, Sen M, Zhu C, Mayadas TN.

Nat Commun. 2018 Nov 29;9(1):5058. doi: 10.1038/s41467-018-07506-1.

4.

Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.

Chen B, Vousden KA, Naiman B, Turman S, Sun H, Wang S, Vinall LMK, Kemp BP, Kasturiangan S, Rees DG, Grant E, Hinrichs MJ, Eck S, DiGiandomenico A, Jack Borrok M, Ly N, Xiong X, Gonzalez C, Morehouse C, Wang Y, Zhou Y, Cann J, Zhao W, Koelkebeck H, Okubo K, Mayadas TN, Howe D, Griffiths J, Kolbeck R, Herbst R, Sims GP.

Ann Rheum Dis. 2019 Feb;78(2):228-237. doi: 10.1136/annrheumdis-2018-213523. Epub 2018 Nov 20.

5.

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury.

Okubo K, Kurosawa M, Kamiya M, Urano Y, Suzuki A, Yamamoto K, Hase K, Homma K, Sasaki J, Miyauchi H, Hoshino T, Hayashi M, Mayadas TN, Hirahashi J.

Nat Med. 2018 Feb;24(2):232-238. doi: 10.1038/nm.4462. Epub 2018 Jan 8.

PMID:
29309057
6.

Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases.

Nishi H, Furuhashi K, Cullere X, Saggu G, Miller MJ, Chen Y, Rosetti F, Hamilton SL, Yang L, Pittman SP, Liao J, Herter JM, Berry JC, DeAngelo DJ, Zhu C, Tsokos GC, Mayadas TN.

J Clin Invest. 2017 Oct 2;127(10):3810-3826. doi: 10.1172/JCI94039. Epub 2017 Sep 11.

7.

Lupus and proliferative nephritis are PAD4 independent in murine models.

Gordon RA, Herter JM, Rosetti F, Campbell AM, Nishi H, Kashgarian M, Bastacky SI, Marinov A, Nickerson KM, Mayadas TN, Shlomchik MJ.

JCI Insight. 2017 May 18;2(10). pii: 92926. doi: 10.1172/jci.insight.92926. eCollection 2017 May 18.

8.

ICER is requisite for Th17 differentiation.

Yoshida N, Comte D, Mizui M, Otomo K, Rosetti F, Mayadas TN, Crispín JC, Bradley SJ, Koga T, Kono M, Karampetsou MP, Kyttaris VC, Tenbrock K, Tsokos GC.

Nat Commun. 2016 Sep 29;7:12993. doi: 10.1038/ncomms12993.

9.

Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules.

Buscher K, Wang H, Zhang X, Striewski P, Wirth B, Saggu G, Lütke-Enking S, Mayadas TN, Ley K, Sorokin L, Song J.

Nat Commun. 2016 Mar 4;7:10828. doi: 10.1038/ncomms10828.

10.

The Changing Landscape of Renal Inflammation.

Ernandez T, Mayadas TN.

Trends Mol Med. 2016 Feb;22(2):151-163. doi: 10.1016/j.molmed.2015.12.002. Epub 2016 Jan 7. Review.

11.

AKAP9, a Regulator of Microtubule Dynamics, Contributes to Blood-Testis Barrier Function.

Venkatesh D, Mruk D, Herter JM, Cullere X, Chojnacka K, Cheng CY, Mayadas TN.

Am J Pathol. 2016 Feb;186(2):270-84. doi: 10.1016/j.ajpath.2015.10.007. Epub 2015 Dec 10.

12.

The many faces of Mac-1 in autoimmune disease.

Rosetti F, Mayadas TN.

Immunol Rev. 2016 Jan;269(1):175-93. doi: 10.1111/imr.12373. Review.

PMID:
26683153
13.

AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation.

Herter JM, Grabie N, Cullere X, Azcutia V, Rosetti F, Bennett P, Herter-Sprie GS, Elyaman W, Luscinskas FW, Lichtman AH, Mayadas TN.

Nat Commun. 2015 Dec 18;6:10182. doi: 10.1038/ncomms10182.

14.

The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3.

Cullere X, Plovie E, Bennett PM, MacRae CA, Mayadas TN.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14284-9. doi: 10.1073/pnas.1510495112. Epub 2015 Nov 4.

15.

Dendritic Cells in Kidney Transplant Biopsy Samples Are Associated with T Cell Infiltration and Poor Allograft Survival.

Batal I, De Serres SA, Safa K, Bijol V, Ueno T, Onozato ML, Iafrate AJ, Herter JM, Lichtman AH, Mayadas TN, Guleria I, Rennke HG, Najafian N, Chandraker A.

J Am Soc Nephrol. 2015 Dec;26(12):3102-13. doi: 10.1681/ASN.2014080804. Epub 2015 Apr 8.

16.

A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force.

Rosetti F, Chen Y, Sen M, Thayer E, Azcutia V, Herter JM, Luscinskas FW, Cullere X, Zhu C, Mayadas TN.

Cell Rep. 2015 Mar 17;10(10):1655-1664. doi: 10.1016/j.celrep.2015.02.037. Epub 2015 Mar 12.

17.

TNF receptors: signaling pathways and contribution to renal dysfunction.

Al-Lamki RS, Mayadas TN.

Kidney Int. 2015 Feb;87(2):281-96. doi: 10.1038/ki.2014.285. Epub 2014 Aug 20. Review.

PMID:
25140911
18.

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VAK, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-2530. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.

19.

Midkine, a middle manager of β2 integrins.

Herter JM, Mayadas TN.

Blood. 2014 Mar 20;123(12):1777-9. doi: 10.1182/blood-2014-02-553073. No abstract available.

20.

Functional vascular endothelium derived from human induced pluripotent stem cells.

Adams WJ, Zhang Y, Cloutier J, Kuchimanchi P, Newton G, Sehrawat S, Aird WC, Mayadas TN, Luscinskas FW, García-Cardeña G.

Stem Cell Reports. 2013 Jul 25;1(2):105-13. doi: 10.1016/j.stemcr.2013.06.007. eCollection 2013.

21.

The multifaceted functions of neutrophils.

Mayadas TN, Cullere X, Lowell CA.

Annu Rev Pathol. 2014;9:181-218. doi: 10.1146/annurev-pathol-020712-164023. Epub 2013 Sep 16. Review.

22.

R-spondin3 prevents mesenteric ischemia/reperfusion-induced tissue damage by tightening endothelium and preventing vascular leakage.

Kannan L, Kis-Toth K, Yoshiya K, Thai TH, Sehrawat S, Mayadas TN, Dalle Lucca JJ, Tsokos GC.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14348-53. doi: 10.1073/pnas.1309393110. Epub 2013 Aug 13.

23.

Endothelial TNF receptor 2 induces IRF1 transcription factor-dependent interferon-β autocrine signaling to promote monocyte recruitment.

Venkatesh D, Ernandez T, Rosetti F, Batal I, Cullere X, Luscinskas FW, Zhang Y, Stavrakis G, García-Cardeña G, Horwitz BH, Mayadas TN.

Immunity. 2013 May 23;38(5):1025-37. doi: 10.1016/j.immuni.2013.01.012. Epub 2013 Apr 25.

24.

Interleukin-17 cytokines are critical in development of fatal lupus glomerulonephritis.

Pisitkun P, Ha HL, Wang H, Claudio E, Tivy CC, Zhou H, Mayadas TN, Illei GG, Siebenlist U.

Immunity. 2012 Dec 14;37(6):1104-15. doi: 10.1016/j.immuni.2012.08.014. Epub 2012 Nov 1.

25.

Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo.

Chen K, Nishi H, Travers R, Tsuboi N, Martinod K, Wagner DD, Stan R, Croce K, Mayadas TN.

Blood. 2012 Nov 22;120(22):4421-31. doi: 10.1182/blood-2011-12-401133. Epub 2012 Sep 6.

26.

Human lupus serum induces neutrophil-mediated organ damage in mice that is enabled by Mac-1 deficiency.

Rosetti F, Tsuboi N, Chen K, Nishi H, Ernandez T, Sethi S, Croce K, Stavrakis G, Alcocer-Varela J, Gómez-Martin D, van Rooijen N, Kyttaris VC, Lichtman AH, Tsokos GC, Mayadas TN.

J Immunol. 2012 Oct 1;189(7):3714-23. Epub 2012 Aug 29.

27.

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia.

Fu H, Liu B, Frost JL, Hong S, Jin M, Ostaszewski B, Shankar GM, Costantino IM, Carroll MC, Mayadas TN, Lemere CA.

Glia. 2012 May;60(6):993-1003. doi: 10.1002/glia.22331. Epub 2012 Mar 21.

28.

Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism.

Crispín JC, Apostolidis SA, Rosetti F, Keszei M, Wang N, Terhorst C, Mayadas TN, Tsokos GC.

J Immunol. 2012 Apr 15;188(8):3567-71. doi: 10.4049/jimmunol.1200143. Epub 2012 Mar 14.

29.

Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes.

Gohda T, Niewczas MA, Ficociello LH, Walker WH, Skupien J, Rosetti F, Cullere X, Johnson AC, Crabtree G, Smiles AM, Mayadas TN, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2012 Mar;23(3):516-24. doi: 10.1681/ASN.2011060628. Epub 2012 Jan 19.

30.

Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes.

Niewczas MA, Gohda T, Skupien J, Smiles AM, Walker WH, Rosetti F, Cullere X, Eckfeldt JH, Doria A, Mayadas TN, Warram JH, Krolewski AS.

J Am Soc Nephrol. 2012 Mar;23(3):507-15. doi: 10.1681/ASN.2011060627. Epub 2012 Jan 19.

31.

The β-glucan receptor Dectin-1 activates the integrin Mac-1 in neutrophils via Vav protein signaling to promote Candida albicans clearance.

Li X, Utomo A, Cullere X, Choi MM, Milner DA Jr, Venkatesh D, Yun SH, Mayadas TN.

Cell Host Microbe. 2011 Dec 15;10(6):603-15. doi: 10.1016/j.chom.2011.10.009.

32.

Overview: studying integrins in vivo.

Lowell CA, Mayadas TN.

Methods Mol Biol. 2012;757:369-97. doi: 10.1007/978-1-61779-166-6_22. Review.

33.

Regulation of human neutrophil Fcγ receptor IIa by C5a receptor promotes inflammatory arthritis in mice.

Tsuboi N, Ernandez T, Li X, Nishi H, Cullere X, Mekala D, Hazen M, Köhl J, Lee DM, Mayadas TN.

Arthritis Rheum. 2011 Feb;63(2):467-78. doi: 10.1002/art.30141.

34.

AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties.

Sehrawat S, Ernandez T, Cullere X, Takahashi M, Ono Y, Komarova Y, Mayadas TN.

Blood. 2011 Jan 13;117(2):708-18. doi: 10.1182/blood-2010-02-268870. Epub 2010 Oct 15. Erratum in: Blood. 2011 Dec 22;118(26):6993-4.

35.

Neutrophils: game changers in glomerulonephritis?

Mayadas TN, Rosetti F, Ernandez T, Sethi S.

Trends Mol Med. 2010 Aug;16(8):368-78. doi: 10.1016/j.molmed.2010.06.002. Epub 2010 Jul 29. Review.

36.

Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury.

Mayadas TN, Tsokos GC, Tsuboi N.

Circulation. 2009 Nov 17;120(20):2012-24. doi: 10.1161/CIRCULATIONAHA.108.771170. Review. No abstract available.

37.

Mac-1 (CD11b/CD18) links inflammation and thrombosis after glomerular injury.

Hirahashi J, Hishikawa K, Kaname S, Tsuboi N, Wang Y, Simon DI, Stavrakis G, Shimosawa T, Xiao L, Nagahama Y, Suzuki K, Fujita T, Mayadas TN.

Circulation. 2009 Sep 29;120(13):1255-65. doi: 10.1161/CIRCULATIONAHA.109.873695. Epub 2009 Sep 14.

38.

Immunoregulatory role of TNFalpha in inflammatory kidney diseases.

Ernandez T, Mayadas TN.

Kidney Int. 2009 Aug;76(3):262-76. doi: 10.1038/ki.2009.142. Epub 2009 May 13. Review.

39.

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif.

Lichtnekert J, Vielhauer V, Zecher D, Kulkarni OP, Clauss S, Segerer S, Hornung V, Mayadas TN, Beutler B, Akira S, Anders HJ.

Am J Physiol Renal Physiol. 2009 Apr;296(4):F867-74. doi: 10.1152/ajprenal.90213.2008. Epub 2009 Jan 21.

40.

p120-Catenin regulates leukocyte transmigration through an effect on VE-cadherin phosphorylation.

Alcaide P, Newton G, Auerbach S, Sehrawat S, Mayadas TN, Golan DE, Yacono P, Vincent P, Kowalczyk A, Luscinskas FW.

Blood. 2008 Oct 1;112(7):2770-9. doi: 10.1182/blood-2008-03-147181. Epub 2008 Jul 18.

41.

Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases.

Tsuboi N, Asano K, Lauterbach M, Mayadas TN.

Immunity. 2008 Jun;28(6):833-46. doi: 10.1016/j.immuni.2008.04.013.

42.

Requirement for Vav proteins in post-recruitment neutrophil cytotoxicity in IgG but not complement C3-dependent injury.

Utomo A, Hirahashi J, Mekala D, Asano K, Glogauer M, Cullere X, Mayadas TN.

J Immunol. 2008 May 1;180(9):6279-87.

43.

Role of TNF priming and adhesion molecules in neutrophil recruitment to intravascular immune complexes.

Lauterbach M, O'Donnell P, Asano K, Mayadas TN.

J Leukoc Biol. 2008 Jun;83(6):1423-30. doi: 10.1189/jlb.0607421. Epub 2008 Mar 27.

PMID:
18372339
44.

Neutrophil-selective CD18 silencing using RNA interference in vivo.

Cullere X, Lauterbach M, Tsuboi N, Mayadas TN.

Blood. 2008 Apr 1;111(7):3591-8. doi: 10.1182/blood-2007-12-127837. Epub 2008 Jan 23.

45.

Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function.

Sehrawat S, Cullere X, Patel S, Italiano J Jr, Mayadas TN.

Mol Biol Cell. 2008 Mar;19(3):1261-70. doi: 10.1091/mbc.E06-10-0972. Epub 2008 Jan 2.

46.

Programmed death 1 ligand (PD-L) 1 and PD-L2 limit autoimmune kidney disease: distinct roles.

Menke J, Lucas JA, Zeller GC, Keir ME, Huang XR, Tsuboi N, Mayadas TN, Lan HY, Sharpe AH, Kelley VR.

J Immunol. 2007 Dec 1;179(11):7466-77.

47.

PSGL-1 regulates platelet P-selectin-mediated endothelial activation and shedding of P-selectin from activated platelets.

Dole VS, Bergmeier W, Patten IS, Hirahashi J, Mayadas TN, Wagner DD.

Thromb Haemost. 2007 Oct;98(4):806-12.

PMID:
17938805
48.

Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion.

Ghandour H, Cullere X, Alvarez A, Luscinskas FW, Mayadas TN.

Blood. 2007 Nov 15;110(10):3682-90. Epub 2007 Aug 16.

49.

Delayed wound healing in Mac-1-deficient mice is associated with normal monocyte recruitment.

Sisco M, Chao JD, Kim I, Mogford JE, Mayadas TN, Mustoe TA.

Wound Repair Regen. 2007 Jul-Aug;15(4):566-71.

PMID:
17650101
50.

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