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Items: 40

1.

Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings.

Maynard LH, Smith O, Tilmans NP, Tham E, Hosseinzadeh S, Tan W, Leenay R, May AP, Paulk NK.

Hum Gene Ther Methods. 2019 Dec;30(6):195-205. doi: 10.1089/hgtb.2019.110.

2.

Fast-Seq, a simple method for rapid and inexpensive validation of packaged ssAAV genomes in academic settings.

Maynard LH, Smith O, Tilmans NP, Tham E, Hosseinzadeh S, Tan W, Leenay R, May AP, Paulk NK.

Hum Gene Ther Methods. 2019 Nov 21. doi: 10.1089/hum.2019.110. [Epub ahead of print]

PMID:
31752511
3.

Harnessing type I CRISPR-Cas systems for genome engineering in human cells.

Cameron P, Coons MM, Klompe SE, Lied AM, Smith SC, Vidal B, Donohoue PD, Rotstein T, Kohrs BW, Nyer DB, Kennedy R, Banh LM, Williams C, Toh MS, Irby MJ, Edwards LS, Lin CH, Owen ALG, Künne T, van der Oost J, Brouns SJJ, Slorach EM, Fuller CK, Gradia S, Kanner SB, May AP, Sternberg SH.

Nat Biotechnol. 2019 Dec;37(12):1471-1477. doi: 10.1038/s41587-019-0310-0. Epub 2019 Nov 18.

PMID:
31740839
4.

Nucleic acid cleavage with a hyperthermophilic Cas9 from an uncultured Ignavibacterium.

Schmidt ST, Yu FB, Blainey PC, May AP, Quake SR.

Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23100-23105. doi: 10.1073/pnas.1904273116. Epub 2019 Oct 28.

5.

Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.

Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J.

Nat Biotechnol. 2019 Sep;37(9):1034-1037. doi: 10.1038/s41587-019-0203-2. Epub 2019 Jul 29.

PMID:
31359007
6.

A large CRISPR-induced bystander mutation causes immune dysregulation.

Simeonov DR, Brandt AJ, Chan AY, Cortez JT, Li Z, Woo JM, Lee Y, Carvalho CMB, Indart AC, Roth TL, Zou J, May AP, Lupski JR, Anderson MS, Buaas FW, Rokhsar DS, Marson A.

Commun Biol. 2019 Feb 18;2:70. doi: 10.1038/s42003-019-0321-x. eCollection 2019.

7.

Reprogramming human T cell function and specificity with non-viral genome targeting.

Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A.

Nature. 2018 Jul;559(7714):405-409. doi: 10.1038/s41586-018-0326-5. Epub 2018 Jul 11.

8.

Advances in Industrial Biotechnology Using CRISPR-Cas Systems.

Donohoue PD, Barrangou R, May AP.

Trends Biotechnol. 2018 Feb;36(2):134-146. doi: 10.1016/j.tibtech.2017.07.007. Epub 2017 Aug 1. Review.

PMID:
28778606
9.

Mapping the genomic landscape of CRISPR-Cas9 cleavage.

Cameron P, Fuller CK, Donohoue PD, Jones BN, Thompson MS, Carter MM, Gradia S, Vidal B, Garner E, Slorach EM, Lau E, Banh LM, Lied AM, Edwards LS, Settle AH, Capurso D, Llaca V, Deschamps S, Cigan M, Young JK, May AP.

Nat Methods. 2017 Jun;14(6):600-606. doi: 10.1038/nmeth.4284. Epub 2017 May 1.

PMID:
28459459
10.

DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.

van Overbeek M, Capurso D, Carter MM, Thompson MS, Frias E, Russ C, Reece-Hoyes JS, Nye C, Gradia S, Vidal B, Zheng J, Hoffman GR, Fuller CK, May AP.

Mol Cell. 2016 Aug 18;63(4):633-646. doi: 10.1016/j.molcel.2016.06.037. Epub 2016 Aug 4.

11.

Unraveling the potential of CRISPR-Cas9 for gene therapy.

Barrangou R, May AP.

Expert Opin Biol Ther. 2015 Mar;15(3):311-4. doi: 10.1517/14712598.2015.994501. Epub 2014 Dec 23.

PMID:
25535790
12.

Guide RNA functional modules direct Cas9 activity and orthogonality.

Briner AE, Donohoue PD, Gomaa AA, Selle K, Slorach EM, Nye CH, Haurwitz RE, Beisel CL, May AP, Barrangou R.

Mol Cell. 2014 Oct 23;56(2):333-339. doi: 10.1016/j.molcel.2014.09.019. Epub 2014 Oct 16.

13.

Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex.

Pollen AA, Nowakowski TJ, Shuga J, Wang X, Leyrat AA, Lui JH, Li N, Szpankowski L, Fowler B, Chen P, Ramalingam N, Sun G, Thu M, Norris M, Lebofsky R, Toppani D, Kemp DW 2nd, Wong M, Clerkson B, Jones BN, Wu S, Knutsson L, Alvarado B, Wang J, Weaver LS, May AP, Jones RC, Unger MA, Kriegstein AR, West JA.

Nat Biotechnol. 2014 Oct;32(10):1053-8. doi: 10.1038/nbt.2967. Epub 2014 Aug 3.

14.

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.

Weaver JMJ, Ross-Innes CS, Shannon N, Lynch AG, Forshew T, Barbera M, Murtaza M, Ong CJ, Lao-Sirieix P, Dunning MJ, Smith L, Smith ML, Anderson CL, Carvalho B, O'Donovan M, Underwood TJ, May AP, Grehan N, Hardwick R, Davies J, Oloumi A, Aparicio S, Caldas C, Eldridge MD, Edwards PAW, Rosenfeld N, Tavaré S, Fitzgerald RC; OCCAMS consortium.

Nat Genet. 2014 Aug;46(8):837-843. doi: 10.1038/ng.3013. Epub 2014 Jun 22.

15.

Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.

Shalek AK, Satija R, Shuga J, Trombetta JJ, Gennert D, Lu D, Chen P, Gertner RS, Gaublomme JT, Yosef N, Schwartz S, Fowler B, Weaver S, Wang J, Wang X, Ding R, Raychowdhury R, Friedman N, Hacohen N, Park H, May AP, Regev A.

Nature. 2014 Jun 19;510(7505):363-9. doi: 10.1038/nature13437. Epub 2014 Jun 11.

16.

Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma.

Gossage L, Murtaza M, Slatter AF, Lichtenstein CP, Warren A, Haynes B, Marass F, Roberts I, Shanahan SJ, Claas A, Dunham A, May AP, Rosenfeld N, Forshew T, Eisen T.

Genes Chromosomes Cancer. 2014 Jan;53(1):38-51. doi: 10.1002/gcc.22116. Epub 2013 Oct 29.

PMID:
24166983
17.

High throughput HLA genotyping using 454 sequencing and the Fluidigm Access Array™ System for simplified amplicon library preparation.

Moonsamy PV, Williams T, Bonella P, Holcomb CL, Höglund BN, Hillman G, Goodridge D, Turenchalk GS, Blake LA, Daigle DA, Simen BB, Hamilton A, May AP, Erlich HA.

Tissue Antigens. 2013 Mar;81(3):141-9. doi: 10.1111/tan.12071.

PMID:
23398507
18.

A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors.

Ou HD, Kwiatkowski W, Deerinck TJ, Noske A, Blain KY, Land HS, Soria C, Powers CJ, May AP, Shu X, Tsien RY, Fitzpatrick JA, Long JA, Ellisman MH, Choe S, O'Shea CC.

Cell. 2012 Oct 12;151(2):304-19. doi: 10.1016/j.cell.2012.08.035.

19.

Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.

Forshew T, Murtaza M, Parkinson C, Gale D, Tsui DW, Kaper F, Dawson SJ, Piskorz AM, Jimenez-Linan M, Bentley D, Hadfield J, May AP, Caldas C, Brenton JD, Rosenfeld N.

Sci Transl Med. 2012 May 30;4(136):136ra68. doi: 10.1126/scitranslmed.3003726.

20.

Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.

Totir M, Echols N, Nanao M, Gee CL, Moskaleva A, Gradia S, Iavarone AT, Berger JM, May AP, Zubieta C, Alber T.

PLoS One. 2012;7(2):e32498. doi: 10.1371/journal.pone.0032498. Epub 2012 Feb 29.

21.

The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.

Ou HD, May AP, O'Shea CC.

Wiley Interdiscip Rev Syst Biol Med. 2011 Jan-Feb;3(1):48-73. doi: 10.1002/wsbm.88. Review.

22.

A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function.

Schoeffler AJ, May AP, Berger JM.

Nucleic Acids Res. 2010 Nov;38(21):7830-44. doi: 10.1093/nar/gkq665. Epub 2010 Jul 31.

23.

Efficient macromolecular crystallization using microfluidics and randomized design of screening reagents.

May AP, Segelke BW.

Methods Mol Biol. 2008;426:387-402. doi: 10.1007/978-1-60327-058-8_25.

PMID:
18542878
24.

Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.

Zaccai NR, May AP, Robinson RC, Burtnick LD, Crocker PR, Brossmer R, Kelm S, Jones EY.

J Mol Biol. 2007 Feb 2;365(5):1469-79. Epub 2006 Oct 28.

PMID:
17137591
27.

Conformational changes of p97 during nucleotide hydrolysis determined by small-angle X-Ray scattering.

Davies JM, Tsuruta H, May AP, Weis WI.

Structure. 2005 Feb;13(2):183-95.

29.

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle.

Rouiller I, DeLaBarre B, May AP, Weis WI, Brunger AT, Milligan RA, Wilson-Kubalek EM.

Nat Struct Biol. 2002 Dec;9(12):950-7.

PMID:
12434150
30.

Uncoupling the ATPase activity of the N-ethylmaleimide sensitive factor (NSF) from 20S complex disassembly.

Matveeva EA, May AP, He P, Whiteheart SW.

Biochemistry. 2002 Jan 15;41(2):530-6.

PMID:
11781091
31.

Optimization of debris removal during bladder irrigation.

Coveney VA, Godfrey H, Mahieu M, May AP.

Physiol Meas. 2001 Aug;22(3):523-34.

PMID:
11556672
32.

Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a.

Misura KM, Gonzalez LC Jr, May AP, Scheller RH, Weis WI.

J Biol Chem. 2001 Nov 2;276(44):41301-9. Epub 2001 Aug 30.

33.

Unraveling the mechanism of the vesicle transport ATPase NSF, the N-ethylmaleimide-sensitive factor.

May AP, Whiteheart SW, Weis WI.

J Biol Chem. 2001 Jun 22;276(25):21991-4. Epub 2001 Apr 11. Review. No abstract available.

34.

Sialoadhesin structure.

May AP, Jones EY.

Results Probl Cell Differ. 2001;33:139-51. Review. No abstract available.

PMID:
11190672
35.

Protein-protein interactions in intracellular membrane fusion.

Misura KM, May AP, Weis WI.

Curr Opin Struct Biol. 2000 Dec;10(6):662-71. Review.

PMID:
11114503
36.

Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein.

May AP, Misura KM, Whiteheart SW, Weis WI.

Nat Cell Biol. 1999 Jul;1(3):175-82.

PMID:
10559905
37.

Integrin alpha- and beta 4-subunit-domain homologues in cyanobacterial proteins.

May AP, Ponting CP.

Trends Biochem Sci. 1999 Jan;24(1):12-3. No abstract available.

PMID:
10087915
39.

Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.

May AP, Robinson RC, Vinson M, Crocker PR, Jones EY.

Mol Cell. 1998 Apr;1(5):719-28.

40.

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