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Items: 19


Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.

Maximov PY, Abderrahman B, Fanning SW, Sengupta S, Fan P, Curpan RF, Rincon DMQ, Greenland JA, Rajan SS, Greene GL, Jordan VC.

Mol Pharmacol. 2018 Aug;94(2):812-822. doi: 10.1124/mol.117.111385. Epub 2018 May 8.


A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers.

Maximov PY, Abderrahman B, Curpan RF, Hawsawi YM, Fan P, Jordan VC.

Endocr Relat Cancer. 2018 Feb;25(2):R83-R113. doi: 10.1530/ERC-17-0416. Epub 2017 Nov 21. Review.


Sex steroid induced apoptosis as a rational strategy to treat anti-hormone resistant breast and prostate cancer.

Jordan VC, Fan P, Abderrahman B, Maximov PY, Hawsawi YM, Bhattacharya P, Pokharel N.

Discov Med. 2016 May;21(117):411-27.


Progesterone and Synthetic Progestin Controversies.

Jordan VC, Maximov PY, Fan P.

JAMA Oncol. 2015 Oct;1(7):986-7. doi: 10.1001/jamaoncol.2015.2280. No abstract available.


Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells.

Fan P, Cunliffe HE, Maximov PY, Agboke FA, McDaniel RE, Zou X, Ramos P, Russell ML, Jordan VC.

Mol Cancer Res. 2015 Oct;13(10):1367-76. doi: 10.1158/1541-7786.MCR-14-0494. Epub 2015 Jun 26.


The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.

Fan P, Maximov PY, Curpan RF, Abderrahman B, Jordan VC.

Mol Cell Endocrinol. 2015 Dec 15;418 Pt 3:245-63. doi: 10.1016/j.mce.2015.06.004. Epub 2015 Jun 5. Review.


Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators.

Jordan VC, Curpan R, Maximov PY.

J Natl Cancer Inst. 2015 Apr 2;107(6):djv075. doi: 10.1093/jnci/djv075. Print 2015 Jun.


Pharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients.

Maximov PY, McDaniel RE, Fernandes DJ, Bhatta P, Korostyshevskiy VR, Curpan RF, Jordan VC.

J Natl Cancer Inst. 2014 Sep 24;106(10). pii: dju283. doi: 10.1093/jnci/dju283. Print 2014 Oct.


Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer.

Molloy ME, White BE, Gherezghiher T, Michalsen BT, Xiong R, Patel H, Zhao H, Maximov PY, Jordan VC, Thatcher GR, Tonetti DA.

Mol Cancer Ther. 2014 Nov;13(11):2515-26. doi: 10.1158/1535-7163.MCT-14-0319. Epub 2014 Sep 9.


Simulation with cells in vitro of tamoxifen treatment in premenopausal breast cancer patients with different CYP2D6 genotypes.

Maximov PY, McDaniel RE, Fernandes DJ, Korostyshevskiy VR, Bhatta P, M├╝rdter TE, Flockhart DA, Jordan VC.

Br J Pharmacol. 2014 Dec;171(24):5624-35. doi: 10.1111/bph.12864.


The evolution of nonsteroidal antiestrogens to become selective estrogen receptor modulators.

Craig Jordan V, McDaniel R, Agboke F, Maximov PY.

Steroids. 2014 Nov;90:3-12. doi: 10.1016/j.steroids.2014.06.009. Epub 2014 Jun 17.


Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells.

Maximov PY, Fernandes DJ, McDaniel RE, Myers CB, Curpan RF, Jordan VC.

J Med Chem. 2014 Jun 12;57(11):4569-83. doi: 10.1021/jm500569h. Epub 2014 May 22.


Estrogen-mediated mechanisms to control the growth and apoptosis of breast cancer cells: a translational research success story.

McDaniel RE, Maximov PY, Jordan VC.

Vitam Horm. 2013;93:1-49. doi: 10.1016/B978-0-12-416673-8.00007-1. Review.


Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells.

Sengupta S, Obiorah I, Maximov PY, Curpan R, Jordan VC.

Br J Pharmacol. 2013 May;169(1):167-78. doi: 10.1111/bph.12122.


Models and Mechanisms of Acquired Antihormone Resistance in Breast Cancer: Significant Clinical Progress Despite Limitations.

Sweeney EE, McDaniel RE, Maximov PY, Fan P, Jordan VC.

Horm Mol Biol Clin Investig. 2012 Feb;9(2):143-163.


The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice.

Maximov PY, Lee TM, Jordan VC.

Curr Clin Pharmacol. 2013 May;8(2):135-55. Review.


Species composition of Bacteroidales order bacteria in the feces of healthy people of various ages.

Kulagina EV, Efimov BA, Maximov PY, Kafarskaia LI, Chaplin AV, Shkoporov AN.

Biosci Biotechnol Biochem. 2012;76(1):169-71. Epub 2012 Jan 7.


Structure-function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen.

Maximov PY, Myers CB, Curpan RF, Lewis-Wambi JS, Jordan VC.

J Med Chem. 2010 Apr 22;53(8):3273-83. doi: 10.1021/jm901907u.


The Paradox of Oestradiol-Induced Breast Cancer Cell Growth and Apoptosis.

Maximov PY, Lewis-Wambi JS, Jordan VC.

Curr Signal Transduct Ther. 2009 May 1;4(2):88-102.

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