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Items: 17


Dual Roles for Regulatory T-cell Depletion and Costimulatory Signaling in Agonistic GITR Targeting for Tumor Immunotherapy.

Mahne AE, Mauze S, Joyce-Shaikh B, Xia J, Bowman EP, Beebe AM, Cua DJ, Jain R.

Cancer Res. 2017 Mar 1;77(5):1108-1118. doi: 10.1158/0008-5472.CAN-16-0797. Epub 2016 Oct 20.


The Role of Anti-Drug Antibodies in the Pharmacokinetics, Disposition, Target Engagement, and Efficacy of a GITR Agonist Monoclonal Antibody in Mice.

Brunn ND, Mauze S, Gu D, Wiswell D, Ueda R, Hodges D, Beebe AM, Zhang S, Escandón E.

J Pharmacol Exp Ther. 2016 Mar;356(3):574-86. doi: 10.1124/jpet.115.229864. Epub 2015 Dec 15.


IL-10 elicits IFNγ-dependent tumor immune surveillance.

Mumm JB, Emmerich J, Zhang X, Chan I, Wu L, Mauze S, Blaisdell S, Basham B, Dai J, Grein J, Sheppard C, Hong K, Cutler C, Turner S, LaFace D, Kleinschek M, Judo M, Ayanoglu G, Langowski J, Gu D, Paporello B, Murphy E, Sriram V, Naravula S, Desai B, Medicherla S, Seghezzi W, McClanahan T, Cannon-Carlson S, Beebe AM, Oft M.

Cancer Cell. 2011 Dec 13;20(6):781-96. doi: 10.1016/j.ccr.2011.11.003.


Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy.

Murray HW, Lu CM, Mauze S, Freeman S, Moreira AL, Kaplan G, Coffman RL.

Infect Immun. 2002 Nov;70(11):6284-93.


An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.

Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F.

J Exp Med. 1999 Oct 4;190(7):995-1004.


Leishmania major infection in interleukin-4 and interferon-gamma depleted mice.

Chatelain R, Mauze S, Varkila K, Coffman RL.

Parasite Immunol. 1999 Aug;21(8):423-31.


Experimental Leishmania major infection in mice: role of IL-10.

Chatelain R, Mauze S, Coffman RL.

Parasite Immunol. 1999 Apr;21(4):211-8.


A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells.

Groux H, Cottrez F, Rouleau M, Mauze S, Antonenko S, Hurst S, McNeil T, Bigler M, Roncarolo MG, Coffman RL.

J Immunol. 1999 Feb 1;162(3):1723-9.


CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro.

Read S, Mauze S, Asseman C, Bean A, Coffman R, Powrie F.

Eur J Immunol. 1998 Nov;28(11):3435-47.


CD4+ T-cells in the regulation of inflammatory responses in the intestine.

Powrie F, Mauze S, Coffman RL.

Res Immunol. 1997 Oct-Dec;148(8-9):576-81. Review. No abstract available.


Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice.

Beebe AM, Mauze S, Schork NJ, Coffman RL.

Immunity. 1997 May;6(5):551-7.


Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells.

Leach MW, Bean AG, Mauze S, Coffman RL, Powrie F.

Am J Pathol. 1996 May;148(5):1503-15.


Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells.

Powrie F, Leach MW, Mauze S, Menon S, Caddle LB, Coffman RL.

Immunity. 1994 Oct;1(7):553-62.


Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice.

Powrie F, Leach MW, Mauze S, Caddle LB, Coffman RL.

Int Immunol. 1993 Nov;5(11):1461-71.


A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE.

Kurup VP, Mauze S, Choi H, Seymour BW, Coffman RL.

J Immunol. 1992 Jun 15;148(12):3783-8.


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