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Items: 50

1.

Three-dimensional analysis of single molecule FISH in human colon organoids.

Omerzu M, Fenderico N, de Barbanson B, Sprangers J, de Ridder J, Maurice MM.

Biol Open. 2019 Aug 9;8(8). pii: bio042812. doi: 10.1242/bio.042812.

2.

Wnt Signaling Directs Neuronal Polarity and Axonal Growth.

Stanganello E, Zahavi EE, Burute M, Smits J, Jordens I, Maurice MM, Kapitein LC, Hoogenraad CC.

iScience. 2019 Mar 29;13:318-327. doi: 10.1016/j.isci.2019.02.029. Epub 2019 Mar 2.

3.

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.

Fenderico N, van Scherpenzeel RC, Goldflam M, Proverbio D, Jordens I, Kralj T, Stryeck S, Bass TZ, Hermans G, Ullman C, Aastrup T, Gros P, Maurice MM.

Nat Commun. 2019 Jan 21;10(1):365. doi: 10.1038/s41467-018-08172-z.

4.

Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer.

Spit M, Koo BK, Maurice MM.

Open Biol. 2018 Sep 12;8(9). pii: 180120. doi: 10.1098/rsob.180120. Review.

5.

TMEM59 potentiates Wnt signaling by promoting signalosome formation.

Gerlach JP, Jordens I, Tauriello DVF, van 't Land-Kuper I, Bugter JM, Noordstra I, van der Kooij J, Low TY, Pimentel-Muiños FX, Xanthakis D, Fenderico N, Rabouille C, Heck AJR, Egan DA, Maurice MM.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3996-E4005. doi: 10.1073/pnas.1721321115. Epub 2018 Apr 9.

6.

Investigations of dynamic amyloid-like structures of the Wnt signalling pathway by solid-state NMR.

Ward ME, Daniëls MA, van Kappel EC, Maurice MM, Baldus M.

Chem Commun (Camb). 2018 Apr 17;54(32):3959-3962. doi: 10.1039/C8CC01346B.

PMID:
29561051
7.

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.

Oost KC, van Voorthuijsen L, Fumagalli A, Lindeboom RGH, Sprangers J, Omerzu M, Rodriguez-Colman MJ, Heinz MC, Verlaan-Klink I, Maurice MM, Burgering BMT, van Rheenen J, Vermeulen M, Snippert HJG.

Cell Rep. 2018 Feb 6;22(6):1600-1614. doi: 10.1016/j.celrep.2018.01.033.

8.

Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins.

Ren Z, van Andel H, de Lau W, Hartholt RB, Maurice MM, Clevers H, Kersten MJ, Spaargaren M, Pals ST.

Blood. 2018 Mar 1;131(9):982-994. doi: 10.1182/blood-2017-07-797050. Epub 2017 Dec 6.

9.

Molecular regulation and pharmacological targeting of the β-catenin destruction complex.

van Kappel EC, Maurice MM.

Br J Pharmacol. 2017 Dec;174(24):4575-4588. doi: 10.1111/bph.13922. Epub 2017 Aug 11. Review.

10.

Loss of CYLD expression unleashes Wnt signaling in multiple myeloma and is associated with aggressive disease.

van Andel H, Kocemba KA, de Haan-Kramer A, Mellink CH, Piwowar M, Broijl A, van Duin M, Sonneveld P, Maurice MM, Kersten MJ, Spaargaren M, Pals ST.

Oncogene. 2017 Apr;36(15):2105-2115. doi: 10.1038/onc.2016.368. Epub 2016 Oct 24.

PMID:
27775078
11.

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.

Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM.

Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14.

PMID:
26974125
12.

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

Farin HF, Jordens I, Mosa MH, Basak O, Korving J, Tauriello DV, de Punder K, Angers S, Peters PJ, Maurice MM, Clevers H.

Nature. 2016 Feb 18;530(7590):340-3. doi: 10.1038/nature16937. Epub 2016 Feb 10.

PMID:
26863187
13.

Loss-of-Function Mutations in the WNT Co-receptor LRP6 Cause Autosomal-Dominant Oligodontia.

Massink MP, Créton MA, Spanevello F, Fennis WM, Cune MS, Savelberg SM, Nijman IJ, Maurice MM, van den Boogaard MJ, van Haaften G.

Am J Hum Genet. 2015 Oct 1;97(4):621-6. doi: 10.1016/j.ajhg.2015.08.014. Epub 2015 Sep 17.

14.

USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.

Zlatanou A, Sabbioneda S, Miller ES, Greenwalt A, Aggathanggelou A, Maurice MM, Lehmann AR, Stankovic T, Reverdy C, Colland F, Vaziri C, Stewart GS.

Oncogene. 2016 Feb 25;35(8):965-76. doi: 10.1038/onc.2015.149. Epub 2015 May 11.

PMID:
25961918
15.

Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes.

Gerlach JP, Emmink BL, Nojima H, Kranenburg O, Maurice MM.

Open Biol. 2014 Nov;4(11):140120. doi: 10.1098/rsob.140120.

16.

DEP domains: structurally similar but functionally different.

Consonni SV, Maurice MM, Bos JL.

Nat Rev Mol Cell Biol. 2014 May;15(5):357-62. doi: 10.1038/nrm3791. Epub 2014 Apr 16. Review.

PMID:
24739740
17.

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations.

Minde DP, Radli M, Forneris F, Maurice MM, Rüdiger SG.

PLoS One. 2013 Oct 9;8(10):e77257. doi: 10.1371/journal.pone.0077257. eCollection 2013.

18.

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, Pan F, Zaiss DM, Coffer PJ.

Immunity. 2013 Aug 22;39(2):259-71. doi: 10.1016/j.immuni.2013.05.018.

19.

Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling.

Jung H, Kim BG, Han WH, Lee JH, Cho JY, Park WS, Maurice MM, Han JK, Lee MJ, Finley D, Jho EH.

Oncogenesis. 2013 Aug 19;2:e64. doi: 10.1038/oncsis.2013.28.

20.

Canonical Wnt signaling negatively modulates regulatory T cell function.

van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ.

Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15.

21.

Stochastic machines as a colocalization mechanism for scaffold protein function.

Xue B, Romero PR, Noutsou M, Maurice MM, Rüdiger SG, William AM Jr, Mizianty MJ, Kurgan L, Uversky VN, Dunker AK.

FEBS Lett. 2013 Jun 5;587(11):1587-91. doi: 10.1016/j.febslet.2013.04.006. Epub 2013 Apr 18.

22.

Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTpp.

Minde DP, Maurice MM, Rüdiger SG.

PLoS One. 2012;7(10):e46147. doi: 10.1371/journal.pone.0046147. Epub 2012 Oct 3.

23.

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

Koo BK, Spit M, Jordens I, Low TY, Stange DE, van de Wetering M, van Es JH, Mohammed S, Heck AJ, Maurice MM, Clevers H.

Nature. 2012 Aug 30;488(7413):665-9. doi: 10.1038/nature11308.

PMID:
22895187
24.

Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.

Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, Gerlach JP, Mohammed S, Heck AJ, Maurice MM, Mahmoudi T, Clevers H.

Cell. 2012 Jun 8;149(6):1245-56. doi: 10.1016/j.cell.2012.05.002.

25.

Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts.

Nethe M, de Kreuk BJ, Tauriello DV, Anthony EC, Snoek B, Stumpel T, Salinas PC, Maurice MM, Geerts D, Deelder AM, Hensbergen PJ, Hordijk PL.

J Cell Sci. 2012 Jul 15;125(Pt 14):3430-42. doi: 10.1242/jcs.100925. Epub 2012 Mar 30.

26.

Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled.

Tauriello DV, Jordens I, Kirchner K, Slootstra JW, Kruitwagen T, Bouwman BA, Noutsou M, Rüdiger SG, Schwamborn K, Schambony A, Maurice MM.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):E812-20. doi: 10.1073/pnas.1114802109. Epub 2012 Mar 12.

27.

Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?

Minde DP, Anvarian Z, Rüdiger SG, Maurice MM.

Mol Cancer. 2011 Aug 22;10:101. doi: 10.1186/1476-4598-10-101. Review.

28.

Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded.

Noutsou M, Duarte AM, Anvarian Z, Didenko T, Minde DP, Kuper I, de Ridder I, Oikonomou C, Friedler A, Boelens R, Rüdiger SG, Maurice MM.

J Mol Biol. 2011 Jan 21;405(3):773-86. doi: 10.1016/j.jmb.2010.11.013. Epub 2010 Nov 16.

29.

The various roles of ubiquitin in Wnt pathway regulation.

Tauriello DV, Maurice MM.

Cell Cycle. 2010 Sep 15;9(18):3700-9. doi: 10.4161/cc.9.18.13204. Epub 2010 Sep 25. Review.

30.

Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.

Tauriello DV, Haegebarth A, Kuper I, Edelmann MJ, Henraat M, Canninga-van Dijk MR, Kessler BM, Clevers H, Maurice MM.

Mol Cell. 2010 Mar 12;37(5):607-19. doi: 10.1016/j.molcel.2010.01.035.

31.

Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex.

ten Klooster JP, Jansen M, Yuan J, Oorschot V, Begthel H, Di Giacomo V, Colland F, de Koning J, Maurice MM, Hornbeck P, Clevers H.

Dev Cell. 2009 Apr;16(4):551-62. doi: 10.1016/j.devcel.2009.01.016.

32.

In vivo role of lipid adducts on Wingless.

Franch-Marro X, Wendler F, Griffith J, Maurice MM, Vincent JP.

J Cell Sci. 2008 May 15;121(Pt 10):1587-92. doi: 10.1242/jcs.015958. Epub 2008 Apr 22.

33.

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.

Franch-Marro X, Wendler F, Guidato S, Griffith J, Baena-Lopez A, Itasaki N, Maurice MM, Vincent JP.

Nat Cell Biol. 2008 Feb;10(2):170-7. doi: 10.1038/ncb1678. Epub 2008 Jan 13.

PMID:
18193037
34.

Proteome changes induced by knock-down of the deubiquitylating enzyme HAUSP/USP7.

Kessler BM, Fortunati E, Melis M, Pals CE, Clevers H, Maurice MM.

J Proteome Res. 2007 Nov;6(11):4163-72. Epub 2007 Oct 10.

PMID:
17927229
35.

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP.

van der Horst A, de Vries-Smits AM, Brenkman AB, van Triest MH, van den Broek N, Colland F, Maurice MM, Burgering BM.

Nat Cell Biol. 2006 Oct;8(10):1064-73. Epub 2006 Sep 10.

PMID:
16964248
36.

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.

Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, Dirks RW, Jochemsen AG.

Mol Cell. 2005 May 27;18(5):565-76. Erratum in: Mol Cell. 2005 Jul 1;19(1):143-4.

37.

Thymic selection and peripheral activation of CD8 T cells by the same class I MHC/peptide complex.

Mintern JD, Maurice MM, Ploegh HL, Schott E.

J Immunol. 2004 Jan 1;172(1):699-708.

38.

Characterization of the hyporesponsiveness of synovial T-Cells in rheumatoid arthritis: role of chronic oxidative stress.

Maurice MM, Verweij CL, Breedveld FC.

Drugs Today (Barc). 1999 Apr-May;35(4-5):321-6.

PMID:
12973436
39.

The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).

Vugmeyster Y, Borodovsky A, Maurice MM, Maehr R, Furman MH, Ploegh HL.

Mol Immunol. 2002 Nov;39(7-8):431-41.

PMID:
12413694
40.

Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules.

Schott E, Bertho N, Ge Q, Maurice MM, Ploegh HL.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13735-40. Epub 2002 Oct 8.

41.

Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules.

Maurice MM, Gould DS, Carroll J, Vugmeyster Y, Ploegh HL.

Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7437-42. Epub 2001 Jun 12.

42.

Expression of the thioredoxin-thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis.

Maurice MM, Nakamura H, Gringhuis S, Okamoto T, Yoshida S, Kullmann F, Lechner S, van der Voort EA, Leow A, Versendaal J, Muller-Ladner U, Yodoi J, Tak PP, Breedveld FC, Verweij CL.

Arthritis Rheum. 1999 Nov;42(11):2430-9.

43.
44.

CD28 co-stimulation is intact and contributes to prolonged ex vivo survival of hyporesponsive synovial fluid T cells in rheumatoid arthritis.

Maurice MM, van der Voort EA, Leow A, Levarht N, Breedveld FC, Verweij CL.

Eur J Immunol. 1998 May;28(5):1554-62.

45.

Defective TCR-mediated signaling in synovial T cells in rheumatoid arthritis.

Maurice MM, Lankester AC, Bezemer AC, Geertsma MF, Tak PP, Breedveld FC, van Lier RA, Verweij CL.

J Immunol. 1997 Sep 15;159(6):2973-8.

PMID:
9300721
46.

Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis.

Maurice MM, Nakamura H, van der Voort EA, van Vliet AI, Staal FJ, Tak PP, Breedveld FC, Verweij CL.

J Immunol. 1997 Feb 1;158(3):1458-65.

PMID:
9013992
47.
48.

Joint-derived T cells in rheumatoid arthritis proliferate to antigens present in autologous synovial fluid.

Maurice MM, Res PC, Leow A, van Hall T, Daha MR, Struyk L, van den Elsen P, Breedveld FC, Verweij CL.

Scand J Rheumatol Suppl. 1995;101:169-77.

PMID:
7747121
49.

Simultaneous regulation of CD2 adhesion and signaling functions by a novel CD2 monoclonal antibody.

van Kemenade FJ, Tellegen E, Maurice MM, Lankester AC, Kuijpers TW, Brouwer M, de Jong R, Miedema F, van Lier RA.

J Immunol. 1994 May 1;152(9):4425-32.

PMID:
7512595
50.

Epstein-Barr virus DNA in Reed-Sternberg cells of Hodgkin's disease is frequently associated with CR2 (EBV receptor) expression.

Jiwa NM, Van der Valk P, Mullink H, Vos W, Horstman A, Maurice MM, Olde-Weghuis DE, Walboomers JM, Meijer CJ.

Histopathology. 1992 Jul;21(1):51-7.

PMID:
1321787

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