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Items: 10


Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.

Avogadri F, Zappasodi R, Yang A, Budhu S, Malandro N, Hirschhorn-Cymerman D, Tiwari S, Maughan MF, Olmsted R, Wolchok JD, Merghoub T.

Cancer Immunol Res. 2014 May;2(5):448-58. doi: 10.1158/2326-6066.CIR-13-0220. Epub 2014 Feb 26.


Alphavirus replicon particles expressing TRP-2 provide potent therapeutic effect on melanoma through activation of humoral and cellular immunity.

Avogadri F, Merghoub T, Maughan MF, Hirschhorn-Cymerman D, Morris J, Ritter E, Olmsted R, Houghton AN, Wolchok JD.

PLoS One. 2010 Sep 10;5(9). pii: e12670. doi: 10.1371/journal.pone.0012670.


Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers.

Bernstein DI, Reap EA, Katen K, Watson A, Smith K, Norberg P, Olmsted RA, Hoeper A, Morris J, Negri S, Maughan MF, Chulay JD.

Vaccine. 2009 Dec 11;28(2):484-93. doi: 10.1016/j.vaccine.2009.09.135. Epub 2009 Oct 24.


A novel alphavirus vaccine encoding prostate-specific membrane antigen elicits potent cellular and humoral immune responses.

Durso RJ, Andjelic S, Gardner JP, Margitich DJ, Donovan GP, Arrigale RR, Wang X, Maughan MF, Talarico TL, Olmsted RA, Heston WD, Maddon PJ, Olson WC.

Clin Cancer Res. 2007 Jul 1;13(13):3999-4008.


Comparison of two cancer vaccines targeting tyrosinase: plasmid DNA and recombinant alphavirus replicon particles.

Goldberg SM, Bartido SM, Gardner JP, Guevara-PatiƱo JA, Montgomery SC, Perales MA, Maughan MF, Dempsey J, Donovan GP, Olson WC, Houghton AN, Wolchok JD.

Clin Cancer Res. 2005 Nov 15;11(22):8114-21.


Alphavirus replicon particles containing the gene for HER2/neu inhibit breast cancer growth and tumorigenesis.

Wang X, Wang JP, Maughan MF, Lachman LB.

Breast Cancer Res. 2005;7(1):R145-55. Epub 2004 Nov 29.


Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model.

Eralp Y, Wang X, Wang JP, Maughan MF, Polo JM, Lachman LB.

Breast Cancer Res. 2004;6(4):R275-83. Epub 2004 Apr 7.


Characterization and selection of HIV-1 subtype C isolates for use in vaccine development.

Williamson C, Morris L, Maughan MF, Ping LH, Dryga SA, Thomas R, Reap EA, Cilliers T, van Harmelen J, Pascual A, Ramjee G, Gray G, Johnston R, Karim SA, Swanstrom R.

AIDS Res Hum Retroviruses. 2003 Feb;19(2):133-44.


Two amino acid substitutions in the SIV Nef protein mediate associations with distinct cellular kinases.

Barber SA, Maughan MF, Roos JW, Clements JE.

Virology. 2000 Oct 25;276(2):329-38.


LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication.

Roos JW, Maughan MF, Liao Z, Hildreth JE, Clements JE.

Virology. 2000 Aug 1;273(2):307-15.

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