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Items: 1 to 50 of 78

1.

Adenosine A1 receptor antagonist, L-97-1, improves survival and protects the kidney in a rat model of cecal ligation and puncture induced sepsis.

Wilson CN, Vance CO, Lechner MG, Matuschak GM, Lechner AJ.

Eur J Pharmacol. 2014 Oct 5;740:346-52. doi: 10.1016/j.ejphar.2014.07.012. Epub 2014 Jul 18.

2.

Stratified assessment of the role of inhaled hypertonic saline in reducing cystic fibrosis pulmonary exacerbations: a retrospective analysis.

Dmello D, Nayak RP, Matuschak GM.

BMJ Open. 2011 Jul 18;1(1):e000019. doi: 10.1136/bmjopen-2010-000019.

3.

A novel post-exposure medical countermeasure L-97-1 improves survival and acute lung injury following intratracheal infection with Yersinia pestis.

Wilson CN, Vance CO, Doyle TM, Brink DS, Matuschak GM, Lechner AJ.

Innate Immun. 2012 Jun;18(3):373-89. doi: 10.1177/1753425911411595. Epub 2011 Aug 23.

4.
5.

Outcomes of etomidate in severe sepsis and septic shock.

Dmello D, Taylor S, O'Brien J, Matuschak GM.

Chest. 2010 Dec;138(6):1327-32. doi: 10.1378/chest.10-0790. Epub 2010 Jul 22.

PMID:
20651024
6.

High-frequency percussive ventilation for airway clearance in cystic fibrosis: a brief report.

Dmello D, Nayak RP, Matuschak GM.

Lung. 2010 Dec;188(6):511-3. doi: 10.1007/s00408-010-9252-5. Epub 2010 Jul 3.

PMID:
20602106
7.

Acute hypoxia decreases E. coli LPS-induced cytokine production and NF-kappaB activation in alveolar macrophages.

Matuschak GM, Nayak R, Doyle TM, Lechner AJ.

Respir Physiol Neurobiol. 2010 Jun 30;172(1-2):63-71. doi: 10.1016/j.resp.2010.05.006. Epub 2010 May 12.

8.

Septic shock and nonpulmonary organ dysfunction in pneumonic plague: the role of Yersinia pestis pCD1- vs. pgm- virulence factors.

Doyle TM, Matuschak GM, Lechner AJ.

Crit Care Med. 2010 Jul;38(7):1574-83. doi: 10.1097/CCM.0b013e3181de8ace.

PMID:
20400901
9.

Moderate hypothermia with intracranial pressure monitoring as a therapeutic paradigm for the management of acute liver failure: a systematic review.

Dmello D, Cruz-Flores S, Matuschak GM.

Intensive Care Med. 2010 Feb;36(2):210-3. doi: 10.1007/s00134-009-1702-2. Epub 2009 Oct 22. Review.

PMID:
19847396
10.

Idiopathic Progressive Tracheobronchial Stenosis of 20 Years' Duration: Response to Anti-inflammatory Treatment.

Dmello D, Matuschak GM.

J Bronchology Interv Pulmonol. 2009 Oct;16(4):293-5. doi: 10.1097/LBR.0b013e3181b77ef1.

PMID:
23168598
11.

Portopulmonary hypertension.

Nayak RP, Li D, Matuschak GM.

Curr Gastroenterol Rep. 2009 Feb;11(1):56-63.

PMID:
19166660
12.

Endobronchial leiomyoma: case report and literature review.

Dmello D, Javed A, Espiritu J, Matuschak GM.

J Bronchology Interv Pulmonol. 2009 Jan;16(1):49-51. doi: 10.1097/LBR.0b013e318193bc71.

PMID:
23168470
13.

Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation.

Ndengele MM, Cuzzocrea S, Masini E, Vinci MC, Esposito E, Muscoli C, Petrusca DN, Mollace V, Mazzon E, Li D, Petrache I, Matuschak GM, Salvemini D.

J Pharmacol Exp Ther. 2009 Apr;329(1):64-75. doi: 10.1124/jpet.108.146290. Epub 2008 Nov 25.

14.

Diffuse alveolar hemorrhage following alemtuzumab.

Sachdeva A, Matuschak GM.

Chest. 2008 Jun;133(6):1476-1478. doi: 10.1378/chest.07-2354.

PMID:
18574290
15.

Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity.

Ndengele MM, Cuzzocrea S, Esposito E, Mazzon E, Di Paola R, Matuschak GM, Salvemini D.

FASEB J. 2008 Sep;22(9):3154-64. doi: 10.1096/fj.08-108159. Epub 2008 May 22.

PMID:
18497304
16.

Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation.

Masini E, Giannini L, Nistri S, Cinci L, Mastroianni R, Xu W, Comhair SA, Li D, Cuzzocrea S, Matuschak GM, Salvemini D.

J Pharmacol Exp Ther. 2008 Feb;324(2):548-57. Epub 2007 Nov 27.

PMID:
18042827
17.

Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice.

Muscoli C, Cuzzocrea S, Ndengele MM, Mollace V, Porreca F, Fabrizi F, Esposito E, Masini E, Matuschak GM, Salvemini D.

J Clin Invest. 2007 Nov;117(11):3530-9.

18.

Hypoxia-induced mitogenic factor enhances angiogenesis by promoting proliferation and migration of endothelial cells.

Tong Q, Zheng L, Li B, Wang D, Huang C, Matuschak GM, Li D.

Exp Cell Res. 2006 Nov 1;312(18):3559-69. Epub 2006 Aug 9.

PMID:
16982054
19.
20.

A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock.

Cuzzocrea S, Mazzon E, Di Paola R, Esposito E, Macarthur H, Matuschak GM, Salvemini D.

J Pharmacol Exp Ther. 2006 Oct;319(1):73-81. Epub 2006 Jun 30.

PMID:
16815867
21.
22.

Superoxide potentiates NF-kappaB activation and modulates endotoxin-induced cytokine production in alveolar macrophages.

Ndengele MM, Muscoli C, Wang ZQ, Doyle TM, Matuschak GM, Salvemini D.

Shock. 2005 Feb;23(2):186-93.

PMID:
15665736
23.

Hypoxic suppression of E. coli-induced NF-kappa B and AP-1 transactivation by oxyradical signaling.

Matuschak GM, Lechner AJ, Chen Z, Todi S, Doyle TM, Loftis LL.

Am J Physiol Regul Integr Comp Physiol. 2004 Aug;287(2):R437-45. Epub 2004 Apr 1.

24.

Cocaine enhances susceptibility to endotoxemic shock in a subset of rats.

Knuepfer MM, Bloodgood TA, Matuschak GM, Lechner AJ.

Crit Care Med. 2004 Jan;32(1):175-83.

PMID:
14707577
25.

Multicenter evaluation of a human monoclonal antibody to Enterobacteriaceae common antigen in patients with Gram-negative sepsis.

Albertson TE, Panacek EA, MacArthur RD, Johnson SB, Benjamin E, Matuschak GM, Zaloga G, Maki D, Silverstein J, Tobias JK, Haenftling K, Black G, Cowens JW; MAB-T88 Sepsis Study Group.

Crit Care Med. 2003 Feb;31(2):419-27.

PMID:
12576946
26.

Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines.

Macarthur H, Couri DM, Wilken GH, Westfall TC, Lechner AJ, Matuschak GM, Chen Z, Salvemini D.

Crit Care Med. 2003 Jan;31(1):237-45.

PMID:
12545022
27.

Magnesium in critical illness: metabolism, assessment, and treatment.

Noronha JL, Matuschak GM.

Intensive Care Med. 2002 Jun;28(6):667-79. Epub 2002 Apr 9. Review. No abstract available.

PMID:
12107669
28.

Liver-lung interactions following Escherichia coli bacteremic sepsis and secondary hepatic ischemia/reperfusion injury.

Matuschak GM, Henry KA, Johanns CA, Lechner AJ.

Am J Respir Crit Care Med. 2001 Mar;163(4):1002-9.

PMID:
11282780
29.

Brief hypoxic stress suppresses postbacteremic NF-kappaB activation and TNF-alpha bioactivity in perfused liver.

Loftis LL, Johanns CA, Lechner AJ, Matuschak GM.

Am J Physiol Regul Integr Comp Physiol. 2000 Jul;279(1):R99-R108.

30.

Brief hypoxia differentially regulates LPS-induced IL-1beta and TNF-alpha gene transcription in RAW 264.7 cells.

Ndengele MM, Bellone CJ, Lechner AJ, Matuschak GM.

Am J Physiol Lung Cell Mol Physiol. 2000 Jun;278(6):L1289-96.

31.

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction.

Hotchkiss RS, Swanson PE, Freeman BD, Tinsley KW, Cobb JP, Matuschak GM, Buchman TG, Karl IE.

Crit Care Med. 1999 Jul;27(7):1230-51.

PMID:
10446814
32.

Pulmonary blood flow and flow-dependent metabolic function during acute lung injury: recruitment for better or worse?

Matuschak GM, Zanaboni PB.

Crit Care Med. 1999 Jan;27(1):21-2. No abstract available.

PMID:
9934882
33.

Effect of MTP on TNF-alpha in perfused rat liver after bacteremia and ischemia/reperfusion.

Durham RM, Lechner AJ, Johanns CA, Chen Z, Matuschak GM.

J Surg Res. 1998 May;76(2):179-84.

PMID:
9698520
34.

Cholestatic liver injury increases circulating TNF-alpha and IL-6 and mortality after Escherichia coli endotoxemia.

Lechner AJ, Velasquez A, Knudsen KR, Johanns CA, Tracy TF Jr, Matuschak GM.

Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1550-8.

PMID:
9603137
35.

Upregulation of postbacteremic TNF-alpha and IL-1alpha gene expression by alveolar hypoxia/reoxygenation in perfused rat lungs.

Matuschak GM, Munoz CF, Johanns CA, Rahman R, Lechner AJ.

Am J Respir Crit Care Med. 1998 Feb;157(2):629-37.

PMID:
9476882
36.

Pulmonary Artery Catheter Consensus Conference: the first step.

Taylor RW Jr, Calvin JE, Matuschak GM.

Crit Care Med. 1997 Dec;25(12):2064-5. No abstract available.

PMID:
9403761
37.

Pulmonary dysfunction after surgery involving cardiopulmonary bypass: do we understand the mechanisms?

Matuschak GM.

Crit Care Med. 1997 Nov;25(11):1778-80. No abstract available.

PMID:
9366753
38.

Supranormal oxygen delivery in critical illness.

Matuschak GM.

New Horiz. 1997 Aug;5(3):233-8.

PMID:
9259336
40.

Treatment of severe systemic inflammatory response syndrome and sepsis with a novel bradykinin antagonist, deltibant (CP-0127). Results of a randomized, double-blind, placebo-controlled trial. CP-0127 SIRS and Sepsis Study Group.

Fein AM, Bernard GR, Criner GJ, Fletcher EC, Good JT Jr, Knaus WA, Levy H, Matuschak GM, Shanies HM, Taylor RW, Rodell TC.

JAMA. 1997 Feb 12;277(6):482-7.

PMID:
9020273
42.

Brief hypoxic stress downregulates E. coli-induced IL-1 alpha and IL-1 beta gene expression in perfused liver.

Matuschak GM, Johanns CA, Chen Z, Gaynor J, Lechner AJ.

Am J Physiol. 1996 Nov;271(5 Pt 2):R1311-8.

PMID:
8945969
43.

Circulating cytokine concentrations and outcome prediction in intensive care unit patients: still the tip of the iceberg?

Matuschak GM.

Crit Care Med. 1996 Nov;24(11):1769-71. Review. No abstract available.

PMID:
8917022
44.

Targeting the alveolar epithelium in acute lung injury: keratinocyte growth factor and regulation of the alveolar epithelial barrier.

Matuschak GM, Lechner AJ.

Crit Care Med. 1996 Jun;24(6):905-7. Review. No abstract available.

PMID:
8681585
45.

Lung-liver interactions in sepsis and multiple organ failure syndrome.

Matuschak GM.

Clin Chest Med. 1996 Mar;17(1):83-98. Review. No abstract available.

PMID:
8665792
46.

Bidirectional effects of hepatic ischemia/reperfusion on E. coli-induced TNF-alpha gene expression.

Epperly NA, Lechner AJ, Johanns CA, Webster RO, Matuschak GM.

Am J Physiol. 1996 Jan;270(1 Pt 2):R289-97.

PMID:
8769813
48.

Downregulation of E. coli-induced TNF-alpha expression in perfused liver by hypoxia-reoxygenation.

Wibbenmeyer LA, Lechner AJ, Munoz CF, Matuschak GM.

Am J Physiol. 1995 Feb;268(2 Pt 1):G311-9.

PMID:
7864128
49.

Liver-lung interactions in critical illness.

Matuschak GM.

New Horiz. 1994 Nov;2(4):488-504. Review.

PMID:
7804798
50.

Organ interactions in critical illness: paradigms and mechanisms.

Matuschak GM.

New Horiz. 1994 Nov;2(4):413-4. No abstract available.

PMID:
7804789

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