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Items: 1 to 50 of 286

1.

High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer.

Carpén T, Sorsa T, Jouhi L, Tervahartiala T, Haglund C, Syrjänen S, Tarkkanen J, Mohamed H, Mäkitie A, Hagström J, Mattila PS.

Cancer Immunol Immunother. 2019 Aug;68(8):1263-1272. doi: 10.1007/s00262-019-02362-4. Epub 2019 Jun 25.

PMID:
31240326
2.

In situ hybridization for high-risk HPV E6/E7 mRNA is a superior method for detecting transcriptionally active HPV in oropharyngeal cancer.

Randén-Brady R, Carpén T, Jouhi L, Syrjänen S, Haglund C, Tarkkanen J, Remes S, Mäkitie A, Mattila PS, Silén S, Hagström J.

Hum Pathol. 2019 Aug;90:97-105. doi: 10.1016/j.humpath.2019.05.006. Epub 2019 May 21.

PMID:
31121191
3.

A2ML1 and otitis media: novel variants, differential expression and relevant pathways.

Larson ED, Magno JPM, Steritz MJ, Llanes EGDV, Cardwell J, Pedro M, Roberts TB, Einarsdottir E, Rosanes RAQ, Greenlee C, Santos RAP, Yousaf A, Streubel SO, Santos ATR, Ruiz AG, Lagrana-Villagracia SM, Ray D, Yarza TKL, Scholes MA, Anderson CB, Acharya A; University of Washington Center for Mendelian Genomics, Gubbels SP, Bamshad MJ, Cass SP, Lee NR, Shaikh RS, Nickerson DA, Mohlke KL, Prager JD, Cruz TLG, Yoon PJ, Abes GT, Schwartz DA, Chan AL, Wine TM, Cutiongco-de la Paz EM, Friedman N, Kechris K, Kere J, Leal SM, Yang IV, Patel JA, Tantoco MLC, Riazuddin S, Chan KH, Mattila PS, Reyes-Quintos MRT, Ahmed ZM, Jenkins HA, Chonmaitree T, Hafrén L, Chiong CM, Santos-Cortez RLP.

Hum Mutat. 2019 Apr 22. doi: 10.1002/humu.23769. [Epub ahead of print]

PMID:
31009165
4.

Computational analysis of the evolutionarily conserved Missing In Metastasis/Metastasis Suppressor 1 gene predicts novel interactions, regulatory regions and transcriptional control.

Petrov P, Sarapulov AV, Eöry L, Scielzo C, Scarfò L, Smith J, Burt DW, Mattila PK.

Sci Rep. 2019 Mar 11;9(1):4155. doi: 10.1038/s41598-019-40697-1.

5.

Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity.

Hanif T, Dhaygude K, Kankainen M, Renkonen J, Mattila P, Ojala T, Joenväärä S, Mäkelä M, Pelkonen A, Kauppi P, Haahtela T, Renkonen R, Toppila-Salmi S.

J Allergy Clin Immunol. 2019 Jun;143(6):2293-2296.e11. doi: 10.1016/j.jaci.2019.02.002. Epub 2019 Feb 12. No abstract available.

6.

FUT2 Variants Confer Susceptibility to Familial Otitis Media.

Santos-Cortez RLP, Chiong CM, Frank DN, Ryan AF, Giese APJ, Bootpetch Roberts T, Daly KA, Steritz MJ, Szeremeta W, Pedro M, Pine H, Yarza TKL, Scholes MA, Llanes EGDV, Yousaf S, Friedman N, Tantoco MLC, Wine TM, Labra PJ, Benoit J, Ruiz AG, de la Cruz RAR, Greenlee C, Yousaf A, Cardwell J, Nonato RMA, Ray D, Ong KMC, So E, Robertson CE, Dinwiddie J, Lagrana-Villagracia SM; University of Washington Center for Mendelian Genomics (UWCMG), Gubbels SP, Shaikh RS, Cass SP, Einarsdottir E, Lee NR, Schwartz DA, Gloria-Cruz TLI, Bamshad MJ, Yang IV, Kere J, Abes GT, Prager JD, Riazuddin S, Chan AL, Yoon PJ, Nickerson DA, Cutiongco-de la Paz EM, Streubel SO, Reyes-Quintos MRT, Jenkins HA, Mattila P, Chan KH, Mohlke KL, Leal SM, Hafrén L, Chonmaitree T, Sale MM, Ahmed ZM.

Am J Hum Genet. 2018 Nov 1;103(5):679-690. doi: 10.1016/j.ajhg.2018.09.010. Epub 2018 Oct 25.

7.

Genetic Control of Myelin Plasticity after Chronic Psychosocial Stress.

Laine MA, Trontti K, Misiewicz Z, Sokolowska E, Kulesskaya N, Heikkinen A, Saarnio S, Balcells I, Ameslon P, Greco D, Mattila P, Ellonen P, Paulin L, Auvinen P, Jokitalo E, Hovatta I.

eNeuro. 2018 Jul 11;5(4). pii: ENEURO.0166-18.2018. doi: 10.1523/ENEURO.0166-18.2018. eCollection 2018 Jul-Aug.

8.

Patients with early-stage oropharyngeal cancer can be identified with label-free serum proteomics.

Tuhkuri A, Saraswat M, Mäkitie A, Mattila P, Silén R, Dickinson A, Carpén T, Tohmola T, Joenväärä S, Renkonen S.

Br J Cancer. 2018 Jul;119(2):200-212. doi: 10.1038/s41416-018-0162-2. Epub 2018 Jul 2.

9.

Absence of NEFL in patient-specific neurons in early-onset Charcot-Marie-Tooth neuropathy.

Sainio MT, Ylikallio E, Mäenpää L, Lahtela J, Mattila P, Auranen M, Palmio J, Tyynismaa H.

Neurol Genet. 2018 Jun 5;4(3):e244. doi: 10.1212/NXG.0000000000000244. eCollection 2018 Jun.

10.

Time to deliver: report of the WHO Independent High-Level Commission on NCDs.

Nishtar S, Niinistö S, Sirisena M, Vázquez T, Skvortsova V, Rubinstein A, Mogae FG, Mattila P, Ghazizadeh Hashemi SH, Kariuki S, Narro Robles J, Adewole IF, Sarr AD, Gan KY, Piukala SM, Al Owais ARBM, Hargan E, Alleyne G, Alwan A, Bernaert A, Bloomberg M, Dain K, Frieden T, Patel VH, Kennedy A, Kickbusch I; Commissioners of the WHO Independent High-Level Commission on NCDs.

Lancet. 2018 Jul 21;392(10143):245-252. doi: 10.1016/S0140-6736(18)31258-3. Epub 2018 Jun 1. No abstract available.

PMID:
29866374
11.

Tumor volume as a prognostic marker in p16-positive and p16-negative oropharyngeal cancer patients treated with definitive intensity-modulated radiotherapy.

Carpén T, Saarilahti K, Haglund C, Markkola A, Tarkkanen J, Hagström J, Mattila P, Mäkitie A.

Strahlenther Onkol. 2018 Aug;194(8):759-770. doi: 10.1007/s00066-018-1309-z. Epub 2018 May 17.

PMID:
29774396
12.

Nutritional Value of Commercial Protein-Rich Plant Products.

Mattila P, Mäkinen S, Eurola M, Jalava T, Pihlava JM, Hellström J, Pihlanto A.

Plant Foods Hum Nutr. 2018 Jun;73(2):108-115. doi: 10.1007/s11130-018-0660-7.

13.

Visualization and Quantitative Analysis of the Actin Cytoskeleton Upon B Cell Activation.

Šuštar V, Vainio M, Mattila PK.

Methods Mol Biol. 2018;1707:243-257. doi: 10.1007/978-1-4939-7474-0_18. Review.

PMID:
29388113
14.

Retrospective analysis of capillary hemoglobin recovery in nearly 1 200 000 blood donor returns.

Niittymäki P, Arvas M, Larjo A, Mattila P, Ihalainen J, Syrjälä M, Castrén J, Partanen J.

Blood Adv. 2017 Jun 8;1(14):961-967. doi: 10.1182/bloodadvances.2016004218. eCollection 2017 Jun 13.

15.

Presenting symptoms and clinical findings in HPV-positive and HPV-negative oropharyngeal cancer patients.

Carpén T, Sjöblom A, Lundberg M, Haglund C, Markkola A, Syrjänen S, Tarkkanen J, Mäkitie A, Hagström J, Mattila P.

Acta Otolaryngol. 2018 May;138(5):513-518. doi: 10.1080/00016489.2017.1405279. Epub 2017 Nov 21. Erratum in: Acta Otolaryngol. 2018 Jul;138(7):675.

PMID:
29161981
16.

A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11.

Bhutta MF, Lambie J, Hobson L, Goel A, Hafrén L, Einarsdottir E, Mattila PS, Farrall M, Brown S, Burton MJ.

Sci Rep. 2017 Oct 2;7(1):12496. doi: 10.1038/s41598-017-12784-8.

17.

The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia.

Kumar A, Kankainen M, Parsons A, Kallioniemi O, Mattila P, Heckman CA.

BMC Genomics. 2017 Aug 17;18(1):629. doi: 10.1186/s12864-017-4039-1.

18.

Bioactivities of alternative protein sources and their potential health benefits.

Pihlanto A, Mattila P, Mäkinen S, Pajari AM.

Food Funct. 2017 Oct 18;8(10):3443-3458. doi: 10.1039/c7fo00302a. Review.

PMID:
28804797
19.

The Small Rho GTPase TC10 Modulates B Cell Immune Responses.

Burbage M, Keppler SJ, Montaner B, Mattila PK, Batista FD.

J Immunol. 2017 Sep 1;199(5):1682-1695. doi: 10.4049/jimmunol.1602167. Epub 2017 Jul 26.

20.

Postprandial glycaemic response to berry nectars containing inverted sucrose.

Törrönen R, Hellström J, Mattila P, Kilpi K.

J Nutr Sci. 2017 Jan 26;6:e4. doi: 10.1017/jns.2016.44. eCollection 2017.

21.

RNA sequencing of chorionic villi from recurrent pregnancy loss patients reveals impaired function of basic nuclear and cellular machinery.

Sõber S, Rull K, Reiman M, Ilisson P, Mattila P, Laan M.

Sci Rep. 2016 Dec 8;6:38439. doi: 10.1038/srep38439.

22.

Consumption of chokeberry (Aronia mitschurinii) products modestly lowered blood pressure and reduced low-grade inflammation in patients with mildly elevated blood pressure.

Loo BM, Erlund I, Koli R, Puukka P, Hellström J, Wähälä K, Mattila P, Jula A.

Nutr Res. 2016 Nov;36(11):1222-1230. doi: 10.1016/j.nutres.2016.09.005. Epub 2016 Sep 14.

PMID:
27865620
23.

Comparison of intra-operative characteristics and early post-operative outcomes between endoscopic sinus surgery and balloon sinuplasty.

Koskinen A, Mattila P, Myller J, Penttilä M, Silvola J, Alastalo I, Huhtala H, Hytönen M, Toppila-Salmi S.

Acta Otolaryngol. 2017 Feb;137(2):202-206. doi: 10.1080/00016489.2016.1227476. Epub 2016 Sep 20.

PMID:
27645028
24.

Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion.

Einarsdottir E, Hafrén L, Leinonen E, Bhutta MF, Kentala E, Kere J, Mattila PS.

Sci Rep. 2016 Sep 16;6:33240. doi: 10.1038/srep33240.

25.

Association of BMI-1 and p16 as prognostic factors for head and neck carcinomas.

Lundberg M, Renkonen S, Haglund C, Mattila PS, Leivo I, Hagström J, Mäkitie AA.

Acta Otolaryngol. 2016;136(5):501-5. doi: 10.3109/00016489.2015.1122227. Epub 2016 Jan 12.

PMID:
27052966
26.

High variability in flavonoid contents and composition between different North-European currant (Ribes spp.) varieties.

Mattila PH, Hellström J, Karhu S, Pihlava JM, Veteläinen M.

Food Chem. 2016 Aug 1;204:14-20. doi: 10.1016/j.foodchem.2016.02.056. Epub 2016 Feb 10.

PMID:
26988470
27.

Long-term follow-up after ESS and balloon sinuplasty: Comparison of symptom reduction and patient satisfaction.

Koskinen A, Myller J, Mattila P, Penttilä M, Silvola J, Alastalo I, Huhtala H, Hytönen M, Toppila-Salmi S.

Acta Otolaryngol. 2016;136(5):532-6. doi: 10.3109/00016489.2015.1129553. Epub 2016 Feb 5.

PMID:
26848855
28.

Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling.

Mattila PK, Batista FD, Treanor B.

J Cell Biol. 2016 Feb 1;212(3):267-80. doi: 10.1083/jcb.201504137. Review.

29.

Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.

Gasparrini F, Feest C, Bruckbauer A, Mattila PK, Müller J, Nitschke L, Bray D, Batista FD.

EMBO J. 2016 Feb 1;35(3):258-80. doi: 10.15252/embj.201593027. Epub 2015 Dec 15.

30.

Extensive shift in placental transcriptome profile in preeclampsia and placental origin of adverse pregnancy outcomes.

Sõber S, Reiman M, Kikas T, Rull K, Inno R, Vaas P, Teesalu P, Marti JML, Mattila P, Laan M.

Sci Rep. 2015 Aug 13;5:13336. doi: 10.1038/srep13336.

31.

Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus.

Hafrén L, Einarsdottir E, Kentala E, Hammarén-Malmi S, Bhutta MF, MacArthur CJ, Wilmot B, Casselbrant M, Conley YP, Weeks DE, Mandel EM, Vaarala O, Kallio A, Melin M, Nieminen JK, Leinonen E, Kere J, Mattila PS.

PLoS One. 2015 Jul 15;10(7):e0132551. doi: 10.1371/journal.pone.0132551. eCollection 2015.

32.

IRF4 Deficiency Leads to Altered BCR Signalling Revealed by Enhanced PI3K Pathway, Decreased SHIP Expression and Defected Cytoskeletal Responses.

Budzyńska PM, Niemelä M, Sarapulov AV, Kyläniemi MK, Nera KP, Junttila S, Laiho A, Mattila PK, Alinikula J, Lassila O.

Scand J Immunol. 2015 Nov;82(5):418-28. doi: 10.1111/sji.12343.

33.

Expression of Toll-like receptors in nasal epithelium in allergic rhinitis.

Renkonen J, Toppila-Salmi S, Joenväärä S, Mattila P, Parviainen V, Hagström J, Haglund C, Lehtonen M, Renkonen R.

APMIS. 2015 Aug;123(8):716-25. doi: 10.1111/apm.12408. Epub 2015 Jun 8.

34.

MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation.

Saarikangas J, Kourdougli N, Senju Y, Chazal G, Segerstråle M, Minkeviciene R, Kuurne J, Mattila PK, Garrett L, Hölter SM, Becker L, Racz I, Hans W, Klopstock T, Wurst W, Zimmer A, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, von Ossowski L, Taira T, Lappalainen P, Rivera C, Hotulainen P.

Dev Cell. 2015 Jun 22;33(6):644-59. doi: 10.1016/j.devcel.2015.04.014. Epub 2015 Jun 4.

35.

The influence of a mandibular advancement plate on polysomnography in different grades of obstructive sleep apnea.

Raunio A, Mattila P, Huuskonen U, Oikarinen K, Sándor GK.

J Oral Maxillofac Res. 2015 Mar 30;6(1):e4. doi: 10.5037/jomr.2014.6104. eCollection 2015 Jan-Mar.

36.

Toll-like receptors 3, 7, and 9 in Juvenile nasopharyngeal angiofibroma.

Renkonen S, Cardell LO, Mattila P, Lundberg M, Haglund C, Hagström J, Mäkitie AA.

APMIS. 2015 May;123(5):439-44. doi: 10.1111/apm.12366.

PMID:
25912131
37.

Complete Genome Sequences of Influenza A/H1N1 Strains Isolated from Patients during the 2013-2014 Epidemic Season in Finland.

Jalovaara P, Mishel P, Kallio-Kokko H, Valkonen M, Kantele A, Ikonen N, Julkunen I, Kakkola L, Kutsaya A, Vuorinen T, Mattila P, Almusa H, Kainov D.

Genome Announc. 2015 Mar 12;3(2). pii: e01523-14. doi: 10.1128/genomeA.01523-14.

38.

Molecular control of B cell activation and immunological synapse formation.

Kuokkanen E, Šuštar V, Mattila PK.

Traffic. 2015 Apr;16(4):311-26. doi: 10.1111/tra.12257. Epub 2015 Feb 20. Review.

39.

Influenza pH1N1 Virus Accumulated H275Y Mutation in Neuraminidase during Propagation in MDCK Cells.

Mishel P, Bychkov D, Kallio-Kokko H, Valkonen M, Kantele A, Mattila P, Almusa H, Jalovaara P, Kainov D.

Genome Announc. 2014 Dec 24;2(6). pii: e01349-14. doi: 10.1128/genomeA.01349-14.

40.

Molecular mechanisms of nasal epithelium in rhinitis and rhinosinusitis.

Toppila-Salmi S, van Drunen CM, Fokkens WJ, Golebski K, Mattila P, Joenvaara S, Renkonen J, Renkonen R.

Curr Allergy Asthma Rep. 2015 Feb;15(2):495. doi: 10.1007/s11882-014-0495-8. Review.

41.

Genetic Instability of Influenza pH1N1 Viruses.

Jalovaara P, Bychkov D, Ahtiainen L, Kallio-Kokko H, Valkonen M, Kantele A, Mattila P, Almusa H, Kallioniemi O, Kainov D.

Genome Announc. 2014 Oct 2;2(5). pii: e00841-14. doi: 10.1128/genomeA.00841-14.

42.

Assessing direct and indirect airway hyperresponsiveness in children using impulse oscillometry.

Kalliola S, Malmberg LP, Kajosaari M, Mattila PS, Pelkonen AS, Mäkelä MJ.

Ann Allergy Asthma Immunol. 2014 Aug;113(2):166-72. doi: 10.1016/j.anai.2014.04.026. Epub 2014 Jun 2.

PMID:
24882741
43.

Full-Genome Sequences of Influenza H3N2 Virus Strains Isolated from Finnish Patients during the 2012-2013 Epidemic Season.

Lakspere T, Kallio-Kokko H, Kantele A, Mattila P, Almusa H, Kainov D, Kakkola L.

Genome Announc. 2014 Mar 27;2(2). pii: e00039-14. doi: 10.1128/genomeA.00039-14.

44.

Full-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Finnish Patients from 2009 to 2013.

Lakspere T, Tynell J, Kaloinen M, Vanlede M, Parsons A, Ikonen N, Kallio-Kokko H, Kantele A, Mattila P, Almusa H, Julkunen I, Kainov D, Kakkola L.

Genome Announc. 2014 Jan 16;2(1). pii: e01004-13. doi: 10.1128/genomeA.01004-13.

45.

Rab11a-positive compartments in proximal tubule cells sort fluid-phase and membrane cargo.

Mattila PE, Raghavan V, Rbaibi Y, Baty CJ, Weisz OA.

Am J Physiol Cell Physiol. 2014 Mar 1;306(5):C441-9. doi: 10.1152/ajpcell.00236.2013. Epub 2013 Oct 23.

46.

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM, Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K.

Cancer Discov. 2013 Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20.

47.

Extraintestinal Clostridium difficile infections.

Mattila E, Arkkila P, Mattila PS, Tarkka E, Tissari P, Anttila VJ.

Clin Infect Dis. 2013 Sep;57(6):e148-53. doi: 10.1093/cid/cit392. Epub 2013 Jun 13.

PMID:
23771984
48.

Effect of immobilization, off-loading and zoledronic acid on bone mineral density in patients with acute Charcot neuroarthropathy: a prospective randomized trial.

Pakarinen TK, Laine HJ, Mäenpää H, Kähönen M, Mattila P, Lahtela J.

Foot Ankle Surg. 2013 Jun;19(2):121-4. doi: 10.1016/j.fas.2012.12.007. Epub 2013 Feb 20.

PMID:
23548455
49.

The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.

Mattila PK, Feest C, Depoil D, Treanor B, Montaner B, Otipoby KL, Carter R, Justement LB, Bruckbauer A, Batista FD.

Immunity. 2013 Mar 21;38(3):461-74. doi: 10.1016/j.immuni.2012.11.019. Epub 2013 Mar 14.

50.

Antigenic diversity and seroprevalences of Torque teno viruses in children and adults by ORF2-based immunoassays.

Chen T, Väisänen E, Mattila PS, Hedman K, Söderlund-Venermo M.

J Gen Virol. 2013 Feb;94(Pt 2):409-17. doi: 10.1099/vir.0.046862-0. Epub 2012 Oct 31.

PMID:
23114629

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