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Tracking nitroxyl-derived posttranslational modifications of phospholamban in cardiac myocytes.

Mundiña-Weilenmann CB, Mattiazzi A.

J Gen Physiol. 2019 Jun 3;151(6):718-721. doi: 10.1085/jgp.201912342. Epub 2019 Apr 22. No abstract available.


Clinical outcomes in HIV+/HCV+ coinfected kidney transplant recipients in the pre- and post-direct-acting antiviral therapy eras: 10-Year single center experience.

Camargo JF, Anjan S, Chin-Beckford N, Morris MI, Abbo LM, Simkins J, Ciancio G, Chen LJ, Burke GW, Figueiro J, Guerra G, Kupin WL, Mattiazzi A, Ortigosa-Goggins M, Ram Bhamidimarri K, Roth D.

Clin Transplant. 2019 May;33(5):e13532. doi: 10.1111/ctr.13532. Epub 2019 Apr 4.


Assessing the link between modified 'Teach Back' method and improvement in knowledge of the medical regimen among youth with kidney transplants: The application of digital media.

Chandar JJ, Ludwig DA, Aguirre J, Mattiazzi A, Bielecka M, Defreitas M, Delamater AM.

Patient Educ Couns. 2019 May;102(5):1035-1039. doi: 10.1016/j.pec.2018.12.007. Epub 2018 Dec 12.


Non-β-Blocking Carvedilol Analog, VK-II-86, Prevents Ouabain-Induced Cardiotoxicity.

Gonano LA, Sepúlveda M, Morell M, Toteff T, Racioppi MF, Lascano E, Negroni J, Fernández Ruocco MJ, Medei E, Neiman G, Miriuka SG, Back TG, Chen SRW, Mattiazzi A, Vila Petroff M.

Circ J. 2018 Dec 25;83(1):41-51. doi: 10.1253/circj.CJ-18-0247. Epub 2018 Oct 23.


Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.

Valverde CA, Mazzocchi G, Di Carlo MN, Ciocci Pardo A, Salas N, Ragone MI, Felice JI, Cely-Ortiz A, Consolini AE, Portiansky E, Mosca S, Kranias EG, Wehrens XHT, Mattiazzi A.

Cardiovasc Res. 2019 Mar 1;115(3):556-569. doi: 10.1093/cvr/cvy213.


Antibody-mediated rejection implies a poor prognosis in kidney transplantation: Results from a single center.

Ciancio G, Gaynor JJ, Guerra G, Sageshima J, Roth D, Chen L, Kupin W, Mattiazzi A, Tueros L, Ruiz P, Vianna R, Burke GW 3rd.

Clin Transplant. 2018 Oct;32(10):e13392. doi: 10.1111/ctr.13392. Epub 2018 Sep 23.


SERCA is critical to control the Bowditch effect in the heart.

Balcazar D, Regge V, Santalla M, Meyer H, Paululat A, Mattiazzi A, Ferrero P.

Sci Rep. 2018 Aug 20;8(1):12447. doi: 10.1038/s41598-018-30638-9.


Roux-en-Y gastric bypass is an effective bridge to kidney transplantation: Results from a single center.

Thomas IA, Gaynor JJ, Joseph T, De La Cruz-Munoz N, Sageshima J, Kupin W, Chen LJ, Ciancio G, Burke GW 3rd, Mattiazzi AD, Roth D, Guerra G.

Clin Transplant. 2018 May;32(5):e13232. doi: 10.1111/ctr.13232. Epub 2018 Apr 10.


A cluster of donor-derived Cryptococcus neoformans infection affecting lung, liver, and kidney transplant recipients: Case report and review of literature.

Camargo JF, Simkins J, Schain DC, Gonzalez AA, Alcaide ML, Anjan S, Guerra G, Roth D, Kupin WL, Mattiazzi A, Tan Y, Milikowski C, Morris MI, Abbo LM.

Transpl Infect Dis. 2018 Apr;20(2):e12836. doi: 10.1111/tid.12836. Epub 2018 Feb 12. Review.


Phaeohyphomycosis due to Exophiala infections in solid organ transplant recipients: Case report and literature review.

Oberlin KE, Nichols AJ, Rosa R, Dejman A, Mattiazzi A, Guerra G, Elgart GW, Abbo LM.

Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12723. Epub 2017 Jun 26. Review.


Impact of RyR2 potentiation on myocardial function.

Lascano E, Negroni J, Vila Petroff M, Mattiazzi A.

Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1105-H1109. doi: 10.1152/ajpheart.00855.2016. Epub 2017 Apr 7. Review.


Transplantation of kidneys from hepatitis C-positive donors into hepatitis C virus-infected recipients followed by early initiation of direct acting antiviral therapy: a single-center retrospective study.

Bhamidimarri KR, Ladino M, Pedraza F, Guerra G, Mattiazzi A, Chen L, Ciancio G, Kupin W, Martin P, Burke G, Roth D.

Transpl Int. 2017 Sep;30(9):865-873. doi: 10.1111/tri.12954. Epub 2017 May 2.


Impact of antiretroviral therapy on clinical outcomes in HIV + kidney transplant recipients: Review of 58 cases.

Rosa R, Suarez JF, Lorio MA, Morris MI, Abbo LM, Simkins J, Guerra G, Roth D, Kupin WL, Mattiazzi A, Ciancio G, Chen LJ, Burke GW, Figueiro JM, Ruiz P, Camargo JF.

F1000Res. 2016 Dec 21;5:2893. doi: 10.12688/f1000research.10414.1. eCollection 2016.


Calcium-calmodulin-dependent protein kinase mediates the intracellular signalling pathways of cardiac apoptosis in mice with impaired glucose tolerance.

Federico M, Portiansky EL, Sommese L, Alvarado FJ, Blanco PG, Zanuzzi CN, Dedman J, Kaetzel M, Wehrens XHT, Mattiazzi A, Palomeque J.

J Physiol. 2017 Jun 15;595(12):4089-4108. doi: 10.1113/JP273714. Epub 2017 Mar 2.


Randomized trial of rATg/Daclizumab vs. rATg/Alemtuzumab as dual induction therapy in renal transplantation: Results at 8years of follow-up.

Ciancio G, Gaynor JJ, Guerra G, Sageshima J, Roth D, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Hanson L, Ruiz P, Vianna R, Burke GW 3rd.

Transpl Immunol. 2017 Feb;40:42-50. doi: 10.1016/j.trim.2016.11.004. Epub 2016 Nov 22.


Pilot Randomized Trial of Tacrolimus/Everolimus vs Tacrolimus/Enteric-Coated Mycophenolate Sodium in Adult, Primary Kidney Transplant Recipients at a Single Center.

Ciancio G, Tryphonopoulos P, Gaynor JJ, Guerra G, Sageshima J, Roth D, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Hanson L, Powell RH, Ruiz P, Vianna R, Burke GW 3rd.

Transplant Proc. 2016 Jul-Aug;48(6):2006-10. doi: 10.1016/j.transproceed.2016.03.048.


Pretransplant CD4 Count Influences Immune Reconstitution and Risk of Infectious Complications in Human Immunodeficiency Virus-Infected Kidney Allograft Recipients.

Suarez JF, Rosa R, Lorio MA, Morris MI, Abbo LM, Simkins J, Guerra G, Roth D, Kupin WL, Mattiazzi A, Ciancio G, Chen LJ, Burke GW, Goldstein MJ, Ruiz P, Camargo JF.

Am J Transplant. 2016 Aug;16(8):2463-72. doi: 10.1111/ajt.13782. Epub 2016 Apr 4.


Comparative Study of the Use of Trichloroacetic Acid and Phenolic Acid in the Treatment of Atrophic-Type Acne Scars.

Dalpizzol M, Weber MB, Mattiazzi AP, Manzoni AP.

Dermatol Surg. 2016 Mar;42(3):377-83. doi: 10.1097/DSS.0000000000000606.


Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.

Mazzocchi G, Sommese L, Palomeque J, Felice JI, Di Carlo MN, Fainstein D, Gonzalez P, Contreras P, Skapura D, McCauley MD, Lascano EC, Negroni JA, Kranias EG, Wehrens XH, Valverde CA, Mattiazzi A.

J Physiol. 2016 Jun 1;594(11):3005-30. doi: 10.1113/JP271622. Epub 2016 Feb 2.


Lower tacrolimus trough levels are associated with subsequently higher acute rejection risk during the first 12 months after kidney transplantation.

Gaynor JJ, Ciancio G, Guerra G, Sageshima J, Roth D, Goldstein MJ, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Hanson L, Ruiz P, Vianna R, Burke GW 3rd.

Transpl Int. 2016 Feb;29(2):216-26. doi: 10.1111/tri.12699. Epub 2015 Nov 3.


Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca(2+) release events in a rodent model of early stage diabetes: The arrhythmogenic substrate.

Sommese L, Valverde CA, Blanco P, Castro MC, Rueda OV, Kaetzel M, Dedman J, Anderson ME, Mattiazzi A, Palomeque J.

Int J Cardiol. 2016 Jan 1;202:394-406. doi: 10.1016/j.ijcard.2015.09.022. Epub 2015 Sep 25.


Chasing cardiac physiology and pathology down the CaMKII cascade.

Mattiazzi A, Bassani RA, Escobar AL, Palomeque J, Valverde CA, Vila Petroff M, Bers DM.

Am J Physiol Heart Circ Physiol. 2015 May 15;308(10):H1177-91. doi: 10.1152/ajpheart.00007.2015. Epub 2015 Mar 6. Review.


Multivariable risk of developing new onset diabetes after transplant-results from a single-center study of 481 adult, primary kidney transplant recipients.

Gaynor JJ, Ciancio G, Guerra G, Sageshima J, Hanson L, Roth D, Goldstein MJ, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Barba LJ, Lopez A, Rivas J, Ruiz P, Vianna R, Burke GW 3rd.

Clin Transplant. 2015 Apr;29(4):301-10. doi: 10.1111/ctr.12510. Epub 2015 Feb 18.


Ca2+ Sparks and Ca2+ waves are the subcellular events underlying Ca2+ overload during ischemia and reperfusion in perfused intact hearts.

Mattiazzi A, Argenziano M, Aguilar-Sanchez Y, Mazzocchi G, Escobar AL.

J Mol Cell Cardiol. 2015 Feb;79:69-78. doi: 10.1016/j.yjmcc.2014.10.011. Epub 2014 Oct 28.


Single-centre study of 628 adult, primary kidney transplant recipients showing no unfavourable effect of new-onset diabetes after transplant.

Gaynor JJ, Ciancio G, Guerra G, Sageshima J, Hanson L, Roth D, Goldstein MJ, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Barba LJ, Lopez A, Rivas J, Ruiz P, Vianna R, Burke GW 3rd.

Diabetologia. 2015 Feb;58(2):334-45. doi: 10.1007/s00125-014-3428-0. Epub 2014 Nov 1.


Aging and CaMKII alter intracellular Ca2+ transients and heart rhythm in Drosophila melanogaster.

Santalla M, Valverde CA, Harnichar E, Lacunza E, Aguilar-Fuentes J, Mattiazzi A, Ferrero P.

PLoS One. 2014 Jul 8;9(7):e101871. doi: 10.1371/journal.pone.0101871. eCollection 2014.


CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.

Di Carlo MN, Said M, Ling H, Valverde CA, De Giusti VC, Sommese L, Palomeque J, Aiello EA, Skapura DG, Rinaldi G, Respress JL, Brown JH, Wehrens XH, Salas MA, Mattiazzi A.

J Mol Cell Cardiol. 2014 Sep;74:274-83. doi: 10.1016/j.yjmcc.2014.06.004. Epub 2014 Jun 17.


Increased Na⁺/Ca²⁺ exchanger expression/activity constitutes a point of inflection in the progression to heart failure of hypertensive rats.

Rodriguez JS, Velez Rueda JO, Salas M, Becerra R, Di Carlo MN, Said M, Vittone L, Rinaldi G, Portiansky EL, Mundiña-Weilenmann C, Palomeque J, Mattiazzi A.

PLoS One. 2014 Apr 29;9(4):e96400. doi: 10.1371/journal.pone.0096400. eCollection 2014.


The role of CaMKII regulation of phospholamban activity in heart disease.

Mattiazzi A, Kranias EG.

Front Pharmacol. 2014 Jan 27;5:5. doi: 10.3389/fphar.2014.00005. eCollection 2014. Review.


Lack of clinical association and effect of peripheral WBC counts on immune cell function test in kidney transplant recipients with T-cell depleting induction and steroid-sparing maintenance therapy.

Sageshima J, Ciancio G, Chen L, Dohi T, El-Hinnawi A, Paloyo S, Gaynor JJ, Mattiazzi A, Guerra G, Kupin W, Roth D, Ruiz P, Burke GW 3rd.

Transpl Immunol. 2014 Mar;30(2-3):88-92. doi: 10.1016/j.trim.2014.01.003. Epub 2014 Feb 9.


Randomized trial of three induction antibodies in kidney transplantation: long-term results.

Ciancio G, Gaynor JJ, Guerra G, Sageshima J, Chen L, Mattiazzi A, Roth D, Kupin W, Tueros L, Flores S, Hanson L, Vianna R, Burke GW 3rd.

Transplantation. 2014 Jun 15;97(11):1128-38. doi: 10.1097/01.TP.0000441089.39840.66.


Graft failure due to noncompliance among 628 kidney transplant recipients with long-term follow-up: a single-center observational study.

Gaynor JJ, Ciancio G, Guerra G, Sageshima J, Hanson L, Roth D, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Aminsharifi J, Joshi S, Chediak Z, Ruiz P, Vianna R, Burke GW 3rd.

Transplantation. 2014 May 15;97(9):925-33. doi: 10.1097/01.TP.0000438199.76531.4a.


Successful treatment for graft-versus-host disease after pancreas transplantation.

Chang Jw, Sageshima J, Ciancio G, Mattiazzi A, Chen L, Tsai HL, Ruiz P, Burke GW 3rd.

Clin Transplant. 2014 Feb;28(2):217-22. doi: 10.1111/ctr.12300. Epub 2014 Jan 17.


Highly Sensitized Patients: Miami Transplant Institute Experience.

Mattiazzi AD, Centeno A, Amador A, Fernandez-Bango C, Scowby CD, O'Rourke M, Hill-Matthie T, Patel R, Barrios F, Ruiz P, Chen L, Saghesima J, Ciancio G, Burke GW, Goldstein M, Chandar J, Contreras G, Roth D, Kupin W, Guerra G, Vianna R.

Clin Transpl. 2014:171-8.


Kidney allograft survival of African American and Caucasian American recipients with lupus.

Contreras G, Li H, Gonzalez-Suarez M, Isakova T, Scialla JJ, Pedraza F, Mattiazzi A, Diaz-Wong R, Sageshima J, Brito Y, Guerra G, Acevedo B, Sajid Ali A, Kershaw TJ, Chen L, Burke GW, Kupin W, Ciancio G, Roth D.

Lupus. 2014 Feb;23(2):151-8. doi: 10.1177/0961203313513819. Epub 2013 Dec 2.


A randomized pilot study of donor stem cell infusion in living-related kidney transplant recipients receiving alemtuzumab.

Ciancio G, Sageshima J, Akpinar E, Gaynor JJ, Chen L, Zarak A, Hanson L, Tueros L, Guerra G, Mattiazzi A, Kupin W, Roth D, Ricordi C, Burke GW 3rd.

Transplantation. 2013 Nov 15;96(9):800-6. doi: 10.1097/TP.0b013e3182a0f68c.


Role of CaMKII in post acidosis arrhythmias: a simulation study using a human myocyte model.

Lascano EC, Said M, Vittone L, Mattiazzi A, Mundiña-Weilenmann C, Negroni JA.

J Mol Cell Cardiol. 2013 Jul;60:172-83. doi: 10.1016/j.yjmcc.2013.04.018. Epub 2013 Apr 23.


Disparities among Blacks, Hispanics, and Whites in time from starting dialysis to kidney transplant waitlisting.

Joshi S, Gaynor JJ, Bayers S, Guerra G, Eldefrawy A, Chediak Z, Companioni L, Sageshima J, Chen L, Kupin W, Roth D, Mattiazzi A, Burke GW 3rd, Ciancio G.

Transplantation. 2013 Jan 27;95(2):309-18. doi: 10.1097/TP.0b013e31827191d4.


The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.

Hidalgo CG, Chung CS, Saripalli C, Methawasin M, Hutchinson KR, Tsaprailis G, Labeit S, Mattiazzi A, Granzier HL.

J Mol Cell Cardiol. 2013 Jan;54:90-7. doi: 10.1016/j.yjmcc.2012.11.012. Epub 2012 Dec 5.


Advantage of rapamycin over mycophenolate mofetil when used with tacrolimus for simultaneous pancreas kidney transplants: randomized, single-center trial at 10 years.

Ciancio G, Sageshima J, Chen L, Gaynor JJ, Hanson L, Tueros L, Montenora-Velarde E, Gomez C, Kupin W, Guerra G, Mattiazzi A, Fornoni A, Pugliese A, Roth D, Wolf M, Burke GW 3rd.

Am J Transplant. 2012 Dec;12(12):3363-76. doi: 10.1111/j.1600-6143.2012.04235.x. Epub 2012 Sep 4.


Predisposing factors of diminished survival in simultaneous liver/kidney transplantation.

Hibi T, Sageshima J, Molina E, Ciancio G, Nishida S, Chen L, Arosemena L, Mattiazzi A, Guerra G, Kupin W, Tekin A, Selvaggi G, Levi D, Ruiz P, Livingstone AS, Roth D, Martin P, Tzakis A, Burke GW.

Am J Transplant. 2012 Nov;12(11):2966-73. doi: 10.1111/j.1600-6143.2012.04121.x. Epub 2012 Jun 8.


Early apoptosis in different models of cardiac hypertrophy induced by high renin-angiotensin system activity involves CaMKII.

Velez Rueda JO, Palomeque J, Mattiazzi A.

J Appl Physiol (1985). 2012 Jun;112(12):2110-20. doi: 10.1152/japplphysiol.01383.2011. Epub 2012 Apr 5.


Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias.

Gonano LA, Sepúlveda M, Rico Y, Kaetzel M, Valverde CA, Dedman J, Mattiazzi A, Vila Petroff M.

Circ Arrhythm Electrophysiol. 2011 Dec;4(6):947-57. doi: 10.1161/CIRCEP.111.964908. Epub 2011 Oct 18.


Kidney transplantation outcomes in African-, Hispanic- and Caucasian-Americans with lupus.

Contreras G, Mattiazzi A, Schultz DR, Guerra G, Ladino M, Ortega LM, Garcia-Estrada M, Ramadugu P, Gupta C, Kupin WL, Roth D.

Lupus. 2012 Jan;21(1):3-12. doi: 10.1177/0961203311421208. Epub 2011 Oct 5.


Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias.

Said M, Becerra R, Valverde CA, Kaetzel MA, Dedman JR, Mundiña-Weilenmann C, Wehrens XH, Vittone L, Mattiazzi A.

J Mol Cell Cardiol. 2011 Dec;51(6):936-44. doi: 10.1016/j.yjmcc.2011.08.010. Epub 2011 Aug 19.


Prolonged lymphocyte depletion by single-dose rabbit anti-thymocyte globulin and alemtuzumab in kidney transplantation.

Sageshima J, Ciancio G, Guerra G, Gaynor JJ, Cova D, Zarak A, Chen L, Mattiazzi A, Kupin W, Roth D, Hanson L, Livingstone AS, Ruiz P, Burke GW.

Transpl Immunol. 2011 Sep;25(2-3):104-11. doi: 10.1016/j.trim.2011.07.002. Epub 2011 Jul 19.


Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis.

Fornoni A, Sageshima J, Wei C, Merscher-Gomez S, Aguillon-Prada R, Jauregui AN, Li J, Mattiazzi A, Ciancio G, Chen L, Zilleruelo G, Abitbol C, Chandar J, Seeherunvong W, Ricordi C, Ikehata M, Rastaldi MP, Reiser J, Burke GW 3rd.

Sci Transl Med. 2011 Jun 1;3(85):85ra46. doi: 10.1126/scitranslmed.3002231.


CaMKII regulation of phospholamban and SR Ca2+ load.

Mattiazzi A, Kranias EG.

Heart Rhythm. 2011 May;8(5):784-7. doi: 10.1016/j.hrthm.2010.11.035. Epub 2010 Nov 23. No abstract available.


Recurrence of lupus nephritis after kidney transplantation.

Contreras G, Mattiazzi A, Guerra G, Ortega LM, Tozman EC, Li H, Tamariz L, Carvalho C, Kupin W, Ladino M, LeClercq B, Jaraba I, Carvalho D, Carles E, Roth D.

J Am Soc Nephrol. 2010 Jul;21(7):1200-7. doi: 10.1681/ASN.2009101093. Epub 2010 May 20.


Na+/K+-ATPase inhibition by ouabain induces CaMKII-dependent apoptosis in adult rat cardiac myocytes.

Sapia L, Palomeque J, Mattiazzi A, Petroff MV.

J Mol Cell Cardiol. 2010 Sep;49(3):459-68. doi: 10.1016/j.yjmcc.2010.04.013. Epub 2010 May 4.


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