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Items: 1 to 50 of 57

1.

A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster.

Belovich AN, Aguilar JI, Mabry SJ, Cheng MH, Zanella D, Hamilton PJ, Stanislowski DJ, Shekar A, Foster JD, Bahar I, Matthies HJG, Galli A.

Mol Psychiatry. 2019 Dec 3. doi: 10.1038/s41380-019-0620-0. [Epub ahead of print]

PMID:
31796894
2.

Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.

DiCarlo GE, Aguilar JI, Matthies HJ, Harrison FE, Bundschuh KE, West A, Hashemi P, Herborg F, Rickhag M, Chen H, Gether U, Wallace MT, Galli A.

J Clin Invest. 2019 May 16;129(8):3407-3419. doi: 10.1172/JCI127411.

3.

Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3.

Campbell NG, Shekar A, Aguilar JI, Peng D, Navratna V, Yang D, Morley AN, Duran AM, Galli G, O'Grady B, Ramachandran R, Sutcliffe JS, Sitte HH, Erreger K, Meiler J, Stockner T, Bellan LM, Matthies HJG, Gouaux E, Mchaourab HS, Galli A.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3853-3862. doi: 10.1073/pnas.1816247116. Epub 2019 Feb 12.

4.

Atypical dopamine efflux caused by 3,4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter.

Shekar A, Aguilar JI, Galli G, Cozzi NV, Brandt SD, Ruoho AE, Baumann MH, Matthies HJG, Galli A.

J Chem Neuroanat. 2017 Oct;83-84:69-74. doi: 10.1016/j.jchemneu.2017.01.004. Epub 2017 Feb 3.

5.

Sodium-dependent vitamin C transporter-2 mediates vitamin C transport at the cortical nerve terminal.

Pierce MR, Raj A, Betke KM, Zeidan LN, Matthies HJ, May JM.

J Neurosci Res. 2015 Dec;93(12):1881-90. doi: 10.1002/jnr.23669. Epub 2015 Sep 14.

6.

mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission.

Dadalko OI, Siuta M, Poe A, Erreger K, Matthies HJ, Niswender K, Galli A.

J Neurosci. 2015 Jun 10;35(23):8843-54. doi: 10.1523/JNEUROSCI.0887-15.2015.

7.

Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors.

Cartier E, Hamilton PJ, Belovich AN, Shekar A, Campbell NG, Saunders C, Andreassen TF, Gether U, Veenstra-Vanderweele J, Sutcliffe JS, Ulery-Reynolds PG, Erreger K, Matthies HJ, Galli A.

EBioMedicine. 2015 Feb;2(2):135-146.

8.

Zn(2+) reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder.

Hamilton PJ, Shekar A, Belovich AN, Christianson NB, Campbell NG, Sutcliffe JS, Galli A, Matthies HJ, Erreger K.

Mol Autism. 2015 Feb 24;6:8. doi: 10.1186/s13229-015-0002-7. eCollection 2015.

9.

Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling.

Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, Galés C.

Nat Chem Biol. 2015 Apr;11(4):271-9. doi: 10.1038/nchembio.1766. Epub 2015 Feb 23.

10.

SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking.

Bowton E, Saunders C, Reddy IA, Campbell NG, Hamilton PJ, Henry LK, Coon H, Sakrikar D, Veenstra-VanderWeele JM, Blakely RD, Sutcliffe J, Matthies HJ, Erreger K, Galli A.

Transl Psychiatry. 2014 Oct 14;4:e464. doi: 10.1038/tp.2014.90.

11.

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

Hamilton PJ, Belovich AN, Khelashvili G, Saunders C, Erreger K, Javitch JA, Sitte HH, Weinstein H, Matthies HJG, Galli A.

Nat Chem Biol. 2014 Jul;10(7):582-589. doi: 10.1038/nchembio.1545. Epub 2014 Jun 1. Erratum in: Biol Psychiatry. 2017 Apr 15;81(8):728.

12.

Drosophila melanogaster: a novel animal model for the behavioral characterization of autism-associated mutations in the dopamine transporter gene.

Hamilton PJ, Campbell NG, Sharma S, Erreger K, Hansen FH, Saunders C, Belovich AN, Sahai MA, Cook EH, Gether U, McHaourab HS, Matthies HJ, Sutcliffe JS, Galli A.

Mol Psychiatry. 2013 Dec;18(12):1235. doi: 10.1038/mp.2013.157. No abstract available.

PMID:
24253181
13.

Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function.

Saunders C, Siuta M, Robertson SD, Davis AR, Sauer J, Matthies HJG, Gresch PJ, Airey D, Lindsley CW, Schetz JA, Niswender KD, Veenstra-Vanderweele JM, Galli A.

Neurochem Int. 2014 Jul;73:113-121. doi: 10.1016/j.neuint.2013.09.015. Epub 2013 Sep 30.

14.

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder.

Hamilton PJ, Campbell NG, Sharma S, Erreger K, Herborg Hansen F, Saunders C, Belovich AN; NIH ARRA Autism Sequencing Consortium, Sahai MA, Cook EH, Gether U, McHaourab HS, Matthies HJ, Sutcliffe JS, Galli A.

Mol Psychiatry. 2013 Dec;18(12):1315-23. doi: 10.1038/mp.2013.102. Epub 2013 Aug 27.

15.

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate.

Buchmayer F, Schicker K, Steinkellner T, Geier P, Stübiger G, Hamilton PJ, Jurik A, Stockner T, Yang JW, Montgomery T, Holy M, Hofmaier T, Kudlacek O, Matthies HJ, Ecker GF, Bochkov V, Galli A, Boehm S, Sitte HH.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11642-7. doi: 10.1073/pnas.1220552110. Epub 2013 Jun 24.

16.

Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine-independent processes.

Conrad KL, Davis AR, Silberman Y, Sheffler DJ, Shields AD, Saleh SA, Sen N, Matthies HJ, Javitch JA, Lindsley CW, Winder DG.

Neuropsychopharmacology. 2012 Sep;37(10):2253-66. doi: 10.1038/npp.2012.76. Epub 2012 May 23. Erratum in: Neuropsychopharmacology. 2013 May;38(6):1140.

17.

Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding.

Speed N, Saunders C, Davis AR, Owens WA, Matthies HJ, Saadat S, Kennedy JP, Vaughan RA, Neve RL, Lindsley CW, Russo SJ, Daws LC, Niswender KD, Galli A.

PLoS One. 2011;6(9):e25169. doi: 10.1371/journal.pone.0025169. Epub 2011 Sep 28.

18.

Gamma-tubulin is required for bipolar spindle assembly and for proper kinetochore microtubule attachments during prometaphase I in Drosophila oocytes.

Hughes SE, Beeler JS, Seat A, Slaughter BD, Unruh JR, Bauerly E, Matthies HJ, Hawley RS.

PLoS Genet. 2011 Aug;7(8):e1002209. doi: 10.1371/journal.pgen.1002209. Epub 2011 Aug 11.

19.

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT.

Cremona ML, Matthies HJ, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A.

Nat Neurosci. 2011 Apr;14(4):469-77. doi: 10.1038/nn.2781. Epub 2011 Mar 13. Erratum in: Nat Neurosci. 2011 Dec;14(2):1617.

20.

The three-dimensional structure of the FMO protein from Pelodictyon phaeum and the implications for energy transfer.

Larson CR, Seng CO, Lauman L, Matthies HJ, Wen J, Blankenship RE, Allen JP.

Photosynth Res. 2011 Feb;107(2):139-50. doi: 10.1007/s11120-010-9604-2. Epub 2010 Dec 23.

PMID:
21181557
21.

Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis.

Robertson SD, Matthies HJ, Owens WA, Sathananthan V, Christianson NS, Kennedy JP, Lindsley CW, Daws LC, Galli A.

J Neurosci. 2010 Aug 25;30(34):11305-16. doi: 10.1523/JNEUROSCI.0126-10.2010.

22.

Akt-dependent and isoform-specific regulation of dopamine transporter cell surface expression.

Speed NK, Matthies HJ, Kennedy JP, Vaughan RA, Javitch JA, Russo SJ, Lindsley CW, Niswender K, Galli A.

ACS Chem Neurosci. 2010 Jul 21;1(7):476-81. doi: 10.1021/cn100031t. Epub 2010 May 25.

23.

Rab11 supports amphetamine-stimulated norepinephrine transporter trafficking.

Matthies HJ, Moore JL, Saunders C, Matthies DS, Lapierre LA, Goldenring JR, Blakely RD, Galli A.

J Neurosci. 2010 Jun 9;30(23):7863-77. doi: 10.1523/JNEUROSCI.4574-09.2010.

24.

Metabolic flexibility revealed in the genome of the cyst-forming alpha-1 proteobacterium Rhodospirillum centenum.

Lu YK, Marden J, Han M, Swingley WD, Mastrian SD, Chowdhury SR, Hao J, Helmy T, Kim S, Kurdoglu AA, Matthies HJ, Rollo D, Stothard P, Blankenship RE, Bauer CE, Touchman JW.

BMC Genomics. 2010 May 25;11:325. doi: 10.1186/1471-2164-11-325.

25.

Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder.

Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies HJ, Sen N, Jessen T, Colbran RJ, Caron MG, Javitch JA, Blakely RD, Galli A.

J Neurosci. 2010 Apr 28;30(17):6048-57. doi: 10.1523/JNEUROSCI.5094-09.2010.

26.

cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.

Steiner JA, Carneiro AM, Wright J, Matthies HJ, Prasad HC, Nicki CK, Dostmann WR, Buchanan CC, Corbin JD, Francis SH, Blakely RD.

Mol Brain. 2009 Aug 5;2:26. doi: 10.1186/1756-6606-2-26.

27.

Subcellular localization of the antidepressant-sensitive norepinephrine transporter.

Matthies HJ, Han Q, Shields A, Wright J, Moore JL, Winder DG, Galli A, Blakely RD.

BMC Neurosci. 2009 Jun 23;10:65. doi: 10.1186/1471-2202-10-65.

28.

A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters.

Robertson SD, Matthies HJ, Galli A.

Mol Neurobiol. 2009 Apr;39(2):73-80. doi: 10.1007/s12035-009-8053-4. Epub 2009 Feb 6. Review.

29.

Stoned B mediates sorting of integral synaptic vesicle proteins.

Mohrmann R, Matthies HJ, Woodruff E 3rd, Broadie K.

Neuroscience. 2008 Jun 2;153(4):1048-63. doi: 10.1016/j.neuroscience.2008.02.060. Epub 2008 Mar 6.

30.

The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism.

Swingley WD, Sadekar S, Mastrian SD, Matthies HJ, Hao J, Ramos H, Acharya CR, Conrad AL, Taylor HL, Dejesa LC, Shah MK, O'huallachain ME, Lince MT, Blankenship RE, Beatty JT, Touchman JW.

J Bacteriol. 2007 Feb;189(3):683-90. Epub 2006 Nov 10.

31.

Drosophila Nod protein binds preferentially to the plus ends of microtubules and promotes microtubule polymerization in vitro.

Cui W, Sproul LR, Gustafson SM, Matthies HJ, Gilbert SP, Hawley RS.

Mol Biol Cell. 2005 Nov;16(11):5400-9. Epub 2005 Sep 7.

32.

Rolling blackout, a newly identified PIP2-DAG pathway lipase required for Drosophila phototransduction.

Huang FD, Matthies HJ, Speese SD, Smith MA, Broadie K.

Nat Neurosci. 2004 Oct;7(10):1070-8. Epub 2004 Sep 12.

PMID:
15361878
33.

Ceramidase regulates synaptic vesicle exocytosis and trafficking.

Rohrbough J, Rushton E, Palanker L, Woodruff E, Matthies HJ, Acharya U, Acharya JK, Broadie K.

J Neurosci. 2004 Sep 8;24(36):7789-803.

34.

The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis.

Zhang YQ, Matthies HJ, Mancuso J, Andrews HK, Woodruff E 3rd, Friedman D, Broadie K.

Dev Biol. 2004 Jun 15;270(2):290-307.

35.

Techniques to dissect cellular and subcellular function in the Drosophila nervous system.

Matthies HJ, Broadie K.

Methods Cell Biol. 2003;71:195-265. Review. No abstract available.

PMID:
12884693
36.
37.

Orphan kinesin NOD lacks motile properties but does possess a microtubule-stimulated ATPase activity.

Matthies HJ, Baskin RJ, Hawley RS.

Mol Biol Cell. 2001 Dec;12(12):4000-12.

38.

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function.

Zhang YQ, Bailey AM, Matthies HJ, Renden RB, Smith MA, Speese SD, Rubin GM, Broadie K.

Cell. 2001 Nov 30;107(5):591-603.

39.

Mutations in the alpha-tubulin 67C gene specifically impair achiasmate segregation in Drosophila melanogaster.

Matthies HJ, Messina LG, Namba R, Greer KJ, Walker MY, Hawley RS.

J Cell Biol. 1999 Dec 13;147(6):1137-44.

40.

Identification of novel Drosophila meiotic genes recovered in a P-element screen.

Sekelsky JJ, McKim KS, Messina L, French RL, Hurley WD, Arbel T, Chin GM, Deneen B, Force SJ, Hari KL, Jang JK, Laurençon AC, Madden LD, Matthies HJ, Milliken DB, Page SL, Ring AD, Wayson SM, Zimmerman CC, Hawley RS.

Genetics. 1999 Jun;152(2):529-42.

41.

The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles.

Sharp DJ, McDonald KL, Brown HM, Matthies HJ, Walczak C, Vale RD, Mitchison TJ, Scholey JM.

J Cell Biol. 1999 Jan 11;144(1):125-38.

42.

Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein.

Matthies HJ, McDonald HB, Goldstein LS, Theurkauf WE.

J Cell Biol. 1996 Jul;134(2):455-64.

43.
44.

[Electroneurographic findings in workers exposed to mercury].

Deike H, Deike R, Matthies HJ, Krell D.

Z Gesamte Hyg. 1991 Feb;37(2):70-1. German.

PMID:
1851589
45.
46.

Calmodulin- and protein phosphorylation-independent release of catecholamines from PC-12 cells.

Matthies HJ, Palfrey HC, Miller RJ.

FEBS Lett. 1988 Mar 14;229(2):238-42.

47.

Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release.

Matthies HJ, Palfrey HC, Hirning LD, Miller RJ.

J Neurosci. 1987 Apr;7(4):1198-206.

48.

Benign breast lesions with malignant clinical and mammographic presentations.

Keen ME, Murad TM, Cohen MI, Matthies HJ.

Hum Pathol. 1985 Nov;16(11):1147-52.

PMID:
4054894
49.

Indurative mastopathy: a cause of false-positive mammograms.

Cohen MI, Matthies HJ, Mintzer RA, Keen ME, Murad T.

Radiology. 1985 Apr;155(1):69-71.

PMID:
3975422
50.

Mammography in women less than 40 years of age.

Cohen MI, Mintzer RA, Matthies HJ, Bernstein JR.

Surg Gynecol Obstet. 1985 Mar;160(3):220-2.

PMID:
2983446

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