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Items: 1 to 50 of 116

1.

Cell-specific role of histone deacetylase 6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers.

Ma J, Trinh RT, Mahant ID, Peng B, Matthias P, Heijnen CJ, Kavelaars A.

Pain. 2019 Jul 24. doi: 10.1097/j.pain.0000000000001667. [Epub ahead of print]

PMID:
31356453
2.

HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development.

Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y.

Neuron. 2019 Mar 20;101(6):1117-1133.e5. doi: 10.1016/j.neuron.2019.01.007. Epub 2019 Jan 30.

PMID:
30709655
3.

Acetylation of intrinsically disordered regions regulates phase separation.

Saito M, Hess D, Eglinger J, Fritsch AW, Kreysing M, Weinert BT, Choudhary C, Matthias P.

Nat Chem Biol. 2019 Jan;15(1):51-61. doi: 10.1038/s41589-018-0180-7. Epub 2018 Dec 10.

PMID:
30531905
4.

The Transcriptional Regulation of Germinal Center Formation.

Song S, Matthias PD.

Front Immunol. 2018 Sep 5;9:2026. doi: 10.3389/fimmu.2018.02026. eCollection 2018. Review.

5.

Purification of Unanchored Polyubiquitin Chains from Influenza Virions.

Miyake Y, Matthias P, Yamauchi Y.

Methods Mol Biol. 2018;1836:329-342. doi: 10.1007/978-1-4939-8678-1_16.

PMID:
30151581
6.

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.

Datta M, Staszewski O, Raschi E, Frosch M, Hagemeyer N, Tay TL, Blank T, Kreutzfeldt M, Merkler D, Ziegler-Waldkirch S, Matthias P, Meyer-Luehmann M, Prinz M.

Immunity. 2018 Mar 20;48(3):514-529.e6. doi: 10.1016/j.immuni.2018.02.016. Epub 2018 Mar 13.

7.

Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect.

Messaoudi K, Ali A, Ishaq R, Palazzo A, Sliwa D, Bluteau O, Souquère S, Muller D, Diop KM, Rameau P, Lapierre V, Marolleau JP, Matthias P, Godin I, Pierron G, Thomas SG, Watson SP, Droin N, Vainchenker W, Plo I, Raslova H, Debili N.

Nat Commun. 2017 Nov 27;8(1):1786. doi: 10.1038/s41467-017-01690-2.

8.

Insights on the apparel needs and limitations for athletes with disabilities: The design of wheelchair rugby sports-wear.

Bragança S, Castellucci I, Gill S, Matthias P, Carvalho M, Arezes P.

Appl Ergon. 2018 Feb;67:9-25. doi: 10.1016/j.apergo.2017.09.005. Epub 2017 Sep 18.

PMID:
29122204
9.

A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.

Göschl L, Preglej T, Hamminger P, Bonelli M, Andersen L, Boucheron N, Gülich AF, Müller L, Saferding V, Mufazalov IA, Hirahara K, Seiser C, Matthias P, Penz T, Schuster M, Bock C, Waisman A, Steiner G, Ellmeier W.

J Autoimmun. 2018 Jan;86:51-61. doi: 10.1016/j.jaut.2017.09.008. Epub 2017 Sep 28.

PMID:
28964722
10.

Fetal Alcohol Research Caring for Patients with Prenatal Alcohol Exposure: A Needs Assessment.

Smith VC, Matthias P, Senturias YN, Turchi RM, Williams JF.

J Popul Ther Clin Pharmacol. 2017 Jan 27;24(1):e25-e39. doi: 10.22374/1710-6222.24.1.4.

PMID:
28186713
11.

Histone deacetylase 1 plays a predominant pro-oncogenic role in Eμ-myc driven B cell lymphoma.

Pillonel V, Reichert N, Cao C, Heideman MR, Yamaguchi T, Matthias G, Tzankov A, Matthias P.

Sci Rep. 2016 Nov 25;6:37772. doi: 10.1038/srep37772.

12.

Structural insights into HDAC6 tubulin deacetylation and its selective inhibition.

Miyake Y, Keusch JJ, Wang L, Saito M, Hess D, Wang X, Melancon BJ, Helquist P, Gut H, Matthias P.

Nat Chem Biol. 2016 Sep;12(9):748-54. doi: 10.1038/nchembio.2140. Epub 2016 Jul 25.

PMID:
27454931
13.

Enhancer repertoires are reshaped independently of early priming and heterochromatin dynamics during B cell differentiation.

Choukrallah MA, Song S, Rolink AG, Burger L, Matthias P.

Nat Commun. 2015 Oct 19;6:8324. doi: 10.1038/ncomms9324.

14.

The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility.

Tang F, Gill J, Ficht X, Barthlott T, Cornils H, Schmitz-Rohmer D, Hynx D, Zhou D, Zhang L, Xue G, Grzmil M, Yang Z, Hergovich A, Hollaender GA, Stein JV, Hemmings BA, Matthias P.

Sci Signal. 2015 Oct 6;8(397):ra100. doi: 10.1126/scisignal.aab2425.

PMID:
26443704
15.

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins.

Brügger V, Engler S, Pereira JA, Ruff S, Horn M, Welzl H, Münger E, Vaquié A, Sidiropoulos PN, Egger B, Yotovski P, Filgueira L, Somandin C, Lühmann TC, D'Antonio M, Yamaguchi T, Matthias P, Suter U, Jacob C.

PLoS Biol. 2015 Sep 25;13(9):e1002258. doi: 10.1371/journal.pbio.1002258. eCollection 2015.

16.

De novo DNA Methyltransferases Dnmt3a and Dnmt3b regulate the onset of Igκ light chain rearrangement during early B-cell development.

Manoharan A, Du Roure C, Rolink AG, Matthias P.

Eur J Immunol. 2015 Aug;45(8):2343-55. doi: 10.1002/eji.201445035. Epub 2015 Jun 16.

17.

Acetylation site specificities of lysine deacetylase inhibitors in human cells.

Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE, Choudhary C.

Nat Biotechnol. 2015 Apr;33(4):415-23. doi: 10.1038/nbt.3130. Epub 2015 Mar 9.

PMID:
25751058
18.

Histone deacetylase 6 is a FoxO transcription factor-dependent effector in skeletal muscle atrophy.

Ratti F, Ramond F, Moncollin V, Simonet T, Milan G, Méjat A, Thomas JL, Streichenberger N, Gilquin B, Matthias P, Khochbin S, Sandri M, Schaeffer L.

J Biol Chem. 2015 Feb 13;290(7):4215-24. doi: 10.1074/jbc.M114.600916. Epub 2014 Dec 15.

19.

Influenza A virus uses the aggresome processing machinery for host cell entry.

Banerjee I, Miyake Y, Nobs SP, Schneider C, Horvath P, Kopf M, Matthias P, Helenius A, Yamauchi Y.

Science. 2014 Oct 24;346(6208):473-7. doi: 10.1126/science.1257037.

20.

HDAC1 controls CD8+ T cell homeostasis and antiviral response.

Tschismarov R, Firner S, Gil-Cruz C, Göschl L, Boucheron N, Steiner G, Matthias P, Seiser C, Ludewig B, Ellmeier W.

PLoS One. 2014 Oct 21;9(10):e110576. doi: 10.1371/journal.pone.0110576. eCollection 2014.

21.

HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.

Zhang M, Xiang S, Joo HY, Wang L, Williams KA, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz RE, Jones A, Schmidt KH, Tang J, Dong H, Shan B, Fang B, Radhakrishnan R, Glazer PM, Matthias P, Koomen J, Seto E, Bepler G, Nicosia SV, Chen J, Li C, Gu L, Li GM, Bai W, Wang H, Zhang X.

Mol Cell. 2014 Jul 3;55(1):31-46. doi: 10.1016/j.molcel.2014.04.028. Epub 2014 May 29.

22.

The Interplay between Chromatin and Transcription Factor Networks during B Cell Development: Who Pulls the Trigger First?

Choukrallah MA, Matthias P.

Front Immunol. 2014 Apr 11;5:156. doi: 10.3389/fimmu.2014.00156. eCollection 2014. Review.

23.

HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.

Jacob C, Lötscher P, Engler S, Baggiolini A, Varum Tavares S, Brügger V, John N, Büchmann-Møller S, Snider PL, Conway SJ, Yamaguchi T, Matthias P, Sommer L, Mantei N, Suter U.

J Neurosci. 2014 Apr 23;34(17):6112-22. doi: 10.1523/JNEUROSCI.5212-13.2014.

24.

Hematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophils.

Du Roure C, Versavel A, Doll T, Cao C, Pillonel V, Matthias G, Kaller M, Spetz JF, Kopp P, Kohler H, Müller M, Matthias P.

PLoS One. 2014 Apr 18;9(4):e92836. doi: 10.1371/journal.pone.0092836. eCollection 2014.

25.

CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

Boucheron N, Tschismarov R, Goeschl L, Moser MA, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W.

Nat Immunol. 2014 May;15(5):439-448. doi: 10.1038/ni.2864. Epub 2014 Mar 30. Erratum in: Nat Immunol. 2014 Sep;15(9):894. Goeschl, Lisa [corrected to Göschl, Lisa].

26.

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C.

Development. 2014 Feb;141(3):604-616. doi: 10.1242/dev.100487.

27.

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.

Winter M, Moser MA, Meunier D, Fischer C, Machat G, Mattes K, Lichtenberger BM, Brunmeir R, Weissmann S, Murko C, Humer C, Meischel T, Brosch G, Matthias P, Sibilia M, Seiser C.

EMBO J. 2013 Dec 11;32(24):3176-91. doi: 10.1038/emboj.2013.243. Epub 2013 Nov 15.

28.

Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration.

Williams KA, Zhang M, Xiang S, Hu C, Wu JY, Zhang S, Ryan M, Cox AD, Der CJ, Fang B, Koomen J, Haura E, Bepler G, Nicosia SV, Matthias P, Wang C, Bai W, Zhang X.

J Biol Chem. 2013 Nov 15;288(46):33156-70. doi: 10.1074/jbc.M113.472506. Epub 2013 Oct 2.

29.

Poloxamer-based hydrogels hardening at body core temperature as carriers for cell based therapies: in vitro and in vivo analysis.

Volkmer E, Leicht U, Moritz M, Schwarz C, Wiese H, Milz S, Matthias P, Schloegl W, Friess W, Goettlinger M, Augat P, Schieker M.

J Mater Sci Mater Med. 2013 Sep;24(9):2223-34. doi: 10.1007/s10856-013-4966-6. Epub 2013 May 28.

PMID:
23712537
30.

Too much or too little, how much HDAC activity is good for you?

Matthias P.

Blood. 2013 Mar 14;121(11):1930-1. doi: 10.1182/blood-2013-02-480400.

PMID:
23493769
31.

HDAC6 controls the kinetics of platelet activation.

Sadoul K, Wang J, Diagouraga B, Vitte AL, Buchou T, Rossini T, Polack B, Xi X, Matthias P, Khochbin S.

Blood. 2012 Nov 15;120(20):4215-8. doi: 10.1182/blood-2012-05-428011. Epub 2012 Sep 6.

PMID:
22955928
32.

HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience.

Espallergues J, Teegarden SL, Veerakumar A, Boulden J, Challis C, Jochems J, Chan M, Petersen T, Deneris E, Matthias P, Hahn CG, Lucki I, Beck SG, Berton O.

J Neurosci. 2012 Mar 28;32(13):4400-16. doi: 10.1523/JNEUROSCI.5634-11.2012.

33.

The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis.

Lai JC, Ponti S, Pan D, Kohler H, Skoda RC, Matthias P, Nagamine Y.

Blood. 2012 May 3;119(18):4291-300. doi: 10.1182/blood-2011-08-362954. Epub 2012 Mar 15.

PMID:
22422825
34.

Multiple roles of class I HDACs in proliferation, differentiation, and development.

Reichert N, Choukrallah MA, Matthias P.

Cell Mol Life Sci. 2012 Jul;69(13):2173-87. doi: 10.1007/s00018-012-0921-9. Review.

PMID:
22286122
35.

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis.

Winkler R, Benz V, Clemenz M, Bloch M, Foryst-Ludwig A, Wardat S, Witte N, Trappiel M, Namsolleck P, Mai K, Spranger J, Matthias G, Roloff T, Truee O, Kappert K, Schupp M, Matthias P, Kintscher U.

Diabetes. 2012 Feb;61(2):513-23. doi: 10.2337/db11-0313. Epub 2011 Dec 30.

36.

Interplay between histone deacetylases and autophagy--from cancer therapy to neurodegeneration.

Trüe O, Matthias P.

Immunol Cell Biol. 2012 Jan;90(1):78-84. doi: 10.1038/icb.2011.103. Epub 2011 Nov 29. Review.

PMID:
22124372
37.

Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease.

Bobrowska A, Paganetti P, Matthias P, Bates GP.

PLoS One. 2011;6(6):e20696. doi: 10.1371/journal.pone.0020696. Epub 2011 Jun 3.

38.

Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells.

de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW.

Mol Cell Biol. 2011 May;31(10):2066-78. doi: 10.1128/MCB.05155-11. Epub 2011 Mar 28.

39.

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.

Jacob C, Christen CN, Pereira JA, Somandin C, Baggiolini A, Lötscher P, Ozçelik M, Tricaud N, Meijer D, Yamaguchi T, Matthias P, Suter U.

Nat Neurosci. 2011 Apr;14(4):429-36. doi: 10.1038/nn.2762. Epub 2011 Mar 20.

PMID:
21423190
40.

Protein acetylation and the physiological role of HDACs.

Matthias P, Seiser C, Yoshida M.

J Biomed Biotechnol. 2011;2011:148201. doi: 10.1155/2011/148201. Epub 2011 Oct 25. No abstract available.

41.

Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin.

Edmond V, Moysan E, Khochbin S, Matthias P, Brambilla C, Brambilla E, Gazzeri S, Eymin B.

EMBO J. 2011 Feb 2;30(3):510-23. doi: 10.1038/emboj.2010.333. Epub 2010 Dec 14.

42.

Oct1 is required for mTOR-induced G1 cell cycle arrest via the control of p27(Kip1) expression.

Dalvai M, Schubart K, Besson A, Matthias P.

Cell Cycle. 2010 Oct 1;9(19):3933-44. Epub 2010 Oct 26.

PMID:
20935455
43.

Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitin.

Burschowsky D, Rudolf F, Rabut G, Herrmann T, Peter M, Wider G.

J Biol Chem. 2011 Jan 14;286(2):1364-73. doi: 10.1074/jbc.M110.135038. Epub 2010 Oct 6. Erratum in: J Biol Chem. 2011 May 13;286(19):17398. Matthias, Peter [corrected to Peter, Matthias].

44.

Oct1 regulates trophoblast development during early mouse embryogenesis.

Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, Tapia N, Esch D, Ju JY, Hübner K, Bravo MJ, Schöler HR, Cavaleri F, Matthias P.

Development. 2010 Nov;137(21):3551-60. doi: 10.1242/dev.047027. Epub 2010 Sep 28.

45.

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.

Grausenburger R, Bilic I, Boucheron N, Zupkovitz G, El-Housseiny L, Tschismarov R, Zhang Y, Rembold M, Gaisberger M, Hartl A, Epstein MM, Matthias P, Seiser C, Ellmeier W.

J Immunol. 2010 Sep 15;185(6):3489-97. doi: 10.4049/jimmunol.0903610. Epub 2010 Aug 11.

46.

Epigenetic regulation of a murine retrotransposon by a dual histone modification mark.

Brunmeir R, Lagger S, Simboeck E, Sawicka A, Egger G, Hagelkruys A, Zhang Y, Matthias P, Miller WJ, Seiser C.

PLoS Genet. 2010 Apr 29;6(4):e1000927. doi: 10.1371/journal.pgen.1000927. Erratum in: PLoS Genet. 2011;7(1). doi: 10.1371/annotation/4ec9cbbd-7620-4449-8961-28213e9dadf4.

47.

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS.

Halili MA, Andrews MR, Labzin LI, Schroder K, Matthias G, Cao C, Lovelace E, Reid RC, Le GT, Hume DA, Irvine KM, Matthias P, Fairlie DP, Sweet MJ.

J Leukoc Biol. 2010 Jun;87(6):1103-14. doi: 10.1189/jlb.0509363. Epub 2010 Mar 3.

PMID:
20200406
48.

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression.

Yamaguchi T, Cubizolles F, Zhang Y, Reichert N, Kohler H, Seiser C, Matthias P.

Genes Dev. 2010 Mar 1;24(5):455-69. doi: 10.1101/gad.552310.

49.

Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development.

Bordon A, Bosco N, Du Roure C, Bartholdy B, Kohler H, Matthias G, Rolink AG, Matthias P.

PLoS One. 2008;3(12):e4007. doi: 10.1371/journal.pone.0004007. Epub 2008 Dec 23.

50.

Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.

Karnowski A, Cao C, Matthias G, Carotta S, Corcoran LM, Martensson IL, Skok JA, Matthias P.

PLoS One. 2008;3(10):e3568. doi: 10.1371/journal.pone.0003568. Epub 2008 Oct 30.

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