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Items: 1 to 50 of 163

1.

Current ophthalmology practice patterns for syphilitic uveitis.

Oliver GF, Stathis RM, Furtado JM, Arantes TE, McCluskey PJ, Matthews JM; International Ocular Syphilis Study Group, Smith JR.

Br J Ophthalmol. 2019 Jan 30. pii: bjophthalmol-2018-313207. doi: 10.1136/bjophthalmol-2018-313207. [Epub ahead of print]

PMID:
31021330
2.

Mutation in a flexible linker modulates binding affinity for modular complexes.

Stokes PH, Robertson NO, Silva APG, Estephan T, Trewhella J, Guss JM, Matthews JM.

Proteins. 2019 May;87(5):425-429. doi: 10.1002/prot.25675. Epub 2019 Mar 9.

PMID:
30788856
3.

Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.

Pero JE, Matthews JM, Behm DJ, Brnardic EJ, Brooks C, Budzik BW, Costell MH, Donatelli CA, Eisennagel SH, Erhard K, Fischer MC, Holt DA, Jolivette LJ, Li H, Li P, McAtee JJ, McCleland BW, Pendrak I, Posobiec LM, Rivera KLK, Rivero RA, Roethke TJ, Sender MR, Shu A, Terrell LR, Vaidya K, Xu X, Lawhorn BG.

J Med Chem. 2018 Dec 27;61(24):11209-11220. doi: 10.1021/acs.jmedchem.8b01344. Epub 2018 Dec 12.

PMID:
30500190
4.

A new approach to understanding structure-function relationships in cytochromes P450 by targeting terpene metabolism in the wild.

Wong NR, Liu X, Lloyd H, Colthart AM, Ferrazzoli AE, Cooper DL, Zhuang Y, Esquea P, Futcher J, Pochapsky TM, Matthews JM, Pochapsky TC.

J Inorg Biochem. 2018 Nov;188:96-101. doi: 10.1016/j.jinorgbio.2018.08.006. Epub 2018 Aug 6.

PMID:
30170307
5.

Disparate binding kinetics by an intrinsically disordered domain enables temporal regulation of transcriptional complex formation.

Robertson NO, Smith NC, Manakas A, Mahjoub M, McDonald G, Kwan AH, Matthews JM.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4643-4648. doi: 10.1073/pnas.1714646115. Epub 2018 Apr 16.

6.

1D Self-Assembly and Ice Recrystallization Inhibition Activity of Antifreeze Glycopeptide-Functionalized Perylene Bisimides.

Adam MK, Jarrett-Wilkins C, Beards M, Staykov E, MacFarlane LR, Bell TDM, Matthews JM, Manners I, Faul CFJ, Moens PDJ, Ben RN, Wilkinson BL.

Chemistry. 2018 Jun 4;24(31):7834-7839. doi: 10.1002/chem.201800857. Epub 2018 May 8.

PMID:
29644728
7.

An Embedded Device for Real-Time Noninvasive Intracranial Pressure Estimation.

Matthews JM, Fanelli A, Heldt T.

Acta Neurochir Suppl. 2018;126:85-88. doi: 10.1007/978-3-319-65798-1_18.

PMID:
29492538
8.

Pulmonary Embolism after Arthroscopic Bankart and Rotator Cuff Repair.

Matthews JM, Wessel SS, Pate RC, Chong AC.

Kans J Med. 2017 May 15;10(2):43-46. eCollection 2017 May. No abstract available.

9.

Interactions between LHX3- and ISL1-family LIM-homeodomain transcription factors are conserved in Caenorhabditis elegans.

Bhati M, Llamosas E, Jacques DA, Jeffries CM, Dastmalchi S, Ripin N, Nicholas HR, Matthews JM.

Sci Rep. 2017 Jul 4;7(1):4579. doi: 10.1038/s41598-017-04587-8.

10.

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes.

Chong CE, Venugopal P, Stokes PH, Lee YK, Brautigan PJ, Yeung DTO, Babic M, Engler GA, Lane SW, Klingler-Hoffmann M, Matthews JM, D'Andrea RJ, Brown AL, Hahn CN, Scott HS.

Leukemia. 2018 Jan;32(1):194-202. doi: 10.1038/leu.2017.196. Epub 2017 Jun 23.

11.

Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.

Matthews JM, McNally JJ, Connolly PJ, Xia M, Zhu B, Black S, Chen C, Hou C, Liang Y, Tang Y, Macielag MJ.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5346-5349. doi: 10.1016/j.bmcl.2016.09.025. Epub 2016 Sep 10.

PMID:
27671496
12.

Tetrahydropyrazolo[4,3-c]pyridine derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.

Zhu B, Matthews JM, Xia M, Black S, Chen C, Hou C, Liang Y, Tang Y, Macielag MJ.

Bioorg Med Chem Lett. 2016 Nov 15;26(22):5597-5601. doi: 10.1016/j.bmcl.2016.09.026. Epub 2016 Sep 12.

PMID:
27671499
13.

A Quantitative Fluorescence-Based Assay for Assessing LIM Domain-Peptide Interactions.

Robertson NO, Shah M, Matthews JM.

Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13236-13239. doi: 10.1002/anie.201605964.

PMID:
27647681
14.

Mechanisms of DNA-binding specificity and functional gene regulation by transcription factors.

Smith NC, Matthews JM.

Curr Opin Struct Biol. 2016 Jun;38:68-74. doi: 10.1016/j.sbi.2016.05.006. Epub 2016 Jun 10. Review.

PMID:
27295424
15.

Discovery, characterization and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa.

McCaughey LC, Josts I, Grinter R, White P, Byron O, Tucker NP, Matthews JM, Kleanthous C, Whitchurch CB, Walker D.

Biochem J. 2016 Aug 1;473(15):2345-58. doi: 10.1042/BCJ20160470. Epub 2016 Jun 1.

16.

Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma.

Matthews JM, Bhatt S, Patricelli MP, Nomanbhoy TK, Jiang X, Natkunam Y, Gentles AJ, Martinez E, Zhu D, Chapman JR, Cortizas E, Shyam R, Chinichian S, Advani R, Tan L, Zhang J, Choi HG, Tibshirani R, Buhrlage SJ, Gratzinger D, Verdun R, Gray NS, Lossos IS.

Blood. 2016 Jul 14;128(2):239-48. doi: 10.1182/blood-2016-02-696856. Epub 2016 May 5.

17.
18.

Precise stellar surface gravities from the time scales of convectively driven brightness variations.

Kallinger T, Hekker S, García RA, Huber D, Matthews JM.

Sci Adv. 2016 Jan 1;2(1):e1500654. doi: 10.1126/sciadv.1500654. eCollection 2016 Jan.

19.

GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA.

Wilkinson-White L, Lester KL, Ripin N, Jacques DA, Mitchell Guss J, Matthews JM.

Protein Sci. 2015 Oct;24(10):1649-59. doi: 10.1002/pro.2760. Epub 2015 Aug 20.

20.

GATA2 is required for lymphatic vessel valve development and maintenance.

Kazenwadel J, Betterman KL, Chong CE, Stokes PH, Lee YK, Secker GA, Agalarov Y, Demir CS, Lawrence DM, Sutton DL, Tabruyn SP, Miura N, Salminen M, Petrova TV, Matthews JM, Hahn CN, Scott HS, Harvey NL.

J Clin Invest. 2015 Aug 3;125(8):2979-94. doi: 10.1172/JCI78888. Epub 2015 Jul 27.

21.

Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.

Wienert B, Funnell AP, Norton LJ, Pearson RC, Wilkinson-White LE, Lester K, Vadolas J, Porteus MH, Matthews JM, Quinlan KG, Crossley M.

Nat Commun. 2015 May 14;6:7085. doi: 10.1038/ncomms8085.

PMID:
25971621
22.

Biochemical and biophysical characterisation of haloalkane dehalogenases DmrA and DmrB in Mycobacterium strain JS60 and their role in growth on haloalkanes.

Fung HK, Gadd MS, Drury TA, Cheung S, Guss JM, Coleman NV, Matthews JM.

Mol Microbiol. 2015 Aug;97(3):439-53. doi: 10.1111/mmi.13039. Epub 2015 May 20.

23.

The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers.

Harten SK, Oey H, Bourke LM, Bharti V, Isbel L, Daxinger L, Faou P, Robertson N, Matthews JM, Whitelaw E.

BMC Biol. 2015 Mar 26;13:21. doi: 10.1186/s12915-015-0128-2.

24.

The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.

Joseph S, Kwan AH, Stokes PH, Mackay JP, Cubeddu L, Matthews JM.

PLoS One. 2014 Oct 13;9(10):e109108. doi: 10.1371/journal.pone.0109108. eCollection 2014.

25.

Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA.

Vandevenne M, O'Connell MR, Helder S, Shepherd NE, Matthews JM, Kwan AH, Segal DJ, Mackay JP.

Angew Chem Int Ed Engl. 2014 Jul 21;53(30):7848-52. doi: 10.1002/anie.201402980. Epub 2014 Jul 9.

26.

Asteroseismology. Echography of young stars reveals their evolution.

Zwintz K, Fossati L, Ryabchikova T, Guenther D, Aerts C, Barnes TG, Themeßl N, Lorenz D, Cameron C, Kuschnig R, Pollack-Drs S, Moravveji E, Baglin A, Matthews JM, Moffat AF, Poretti E, Rainer M, Rucinski SM, Sasselov D, Weiss WW.

Science. 2014 Aug 1;345(6196):550-3. doi: 10.1126/science.1253645. Epub 2014 Jul 3.

27.
28.

A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers.

Gamsjaeger R, O'Connell MR, Cubeddu L, Shepherd NE, Lowry JA, Kwan AH, Vandevenne M, Swanton MK, Matthews JM, Mackay JP.

J Biol Chem. 2013 Dec 6;288(49):35180-91. doi: 10.1074/jbc.M113.482075. Epub 2013 Oct 6.

29.

A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.

Gadd MS, Jacques DA, Nisevic I, Craig VJ, Kwan AH, Guss JM, Matthews JM.

J Biol Chem. 2013 Jul 26;288(30):21924-35. doi: 10.1074/jbc.M113.478586. Epub 2013 Jun 9.

30.

Semiquantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in surface plasmon resonance competition experiments.

Gamsjaeger R, Kariawasam R, Bang LH, Touma C, Nguyen CD, Matthews JM, Cubeddu L, Mackay JP.

Anal Biochem. 2013 Sep 15;440(2):178-85. doi: 10.1016/j.ab.2013.04.030. Epub 2013 May 31.

PMID:
23727560
31.

Analysis of disease-causing GATA1 mutations in murine gene complementation systems.

Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA.

Blood. 2013 Jun 27;121(26):5218-27. doi: 10.1182/blood-2013-03-488080. Epub 2013 May 23.

32.

No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations.

Youngson NA, Epp T, Roberts AR, Daxinger L, Ashe A, Huang E, Lester KL, Harten SK, Kay GF, Cox T, Matthews JM, Chong S, Whitelaw E.

Mamm Genome. 2013 Jun;24(5-6):206-17. doi: 10.1007/s00335-013-9451-5. Epub 2013 May 1.

PMID:
23636699
33.

Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules.

Corcilius L, Santhakumar G, Stone RS, Capicciotti CJ, Joseph S, Matthews JM, Ben RN, Payne RJ.

Bioorg Med Chem. 2013 Jun 15;21(12):3569-81. doi: 10.1016/j.bmc.2013.02.025. Epub 2013 Feb 21.

PMID:
23523384
34.

New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217.

Vandevenne M, Jacques DA, Artuz C, Nguyen CD, Kwan AH, Segal DJ, Matthews JM, Crossley M, Guss JM, Mackay JP.

J Biol Chem. 2013 Apr 12;288(15):10616-27. doi: 10.1074/jbc.M112.441451. Epub 2013 Feb 22.

35.

Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1.

Joseph S, Kwan AH, Mackay JP, Cubeddu L, Matthews JM.

Biomol NMR Assign. 2014 Apr;8(1):141-4. doi: 10.1007/s12104-013-9470-x. Epub 2013 Feb 16.

PMID:
23417771
36.

Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.

Zhu B, Xia M, Xu X, Ludovici DW, Tennakoon M, Youngman MA, Matthews JM, Dax SL, Colburn RW, Qin N, Hutchinson TL, Lubin ML, Brandt MR, Stone DJ, Flores CM, Macielag MJ.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):2234-7. doi: 10.1016/j.bmcl.2013.01.062. Epub 2013 Feb 4.

PMID:
23411075
37.

Structural basis of the interaction of the breast cancer oncogene LMO4 with the tumour suppressor CtIP/RBBP8.

Stokes PH, Liew CW, Kwan AH, Foo P, Barker HE, Djamirze A, O'Reilly V, Visvader JE, Mackay JP, Matthews JM.

J Mol Biol. 2013 Apr 12;425(7):1101-10. doi: 10.1016/j.jmb.2013.01.017. Epub 2013 Jan 23.

PMID:
23353824
38.

The tandem β-zipper: modular binding of tandem domains and linear motifs.

Matthews JM, Potts JR.

FEBS Lett. 2013 Apr 17;587(8):1164-71. doi: 10.1016/j.febslet.2013.01.002. Epub 2013 Jan 16. Review.

39.

LIM-domain-only proteins in cancer.

Matthews JM, Lester K, Joseph S, Curtis DJ.

Nat Rev Cancer. 2013 Feb;13(2):111-22. doi: 10.1038/nrc3418. Epub 2013 Jan 10. Review.

PMID:
23303138
40.

Crystallization and diffraction of an Isl1-Ldb1 complex.

Gadd MS, Jacques DA, Guss JM, Matthews JM.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Nov 1;68(Pt 11):1398-401. doi: 10.1107/S1744309112040031. Epub 2012 Oct 30.

41.

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.

Jiang X, Huang H, Li Z, Li Y, Wang X, Gurbuxani S, Chen P, He C, You D, Zhang S, Wang J, Arnovitz S, Elkahloun A, Price C, Hong GM, Ren H, Kunjamma RB, Neilly MB, Matthews JM, Xu M, Larson RA, Le Beau MM, Slany RK, Liu PP, Lu J, Zhang J, He C, Chen J.

Cancer Cell. 2012 Oct 16;22(4):524-35. doi: 10.1016/j.ccr.2012.08.028.

42.

Protein-protein interactions. Preface.

Matthews JM.

Adv Exp Med Biol. 2012;747:v-vi. No abstract available.

PMID:
22977895
43.

Dimers, oligomers, everywhere.

Matthews JM, Sunde M.

Adv Exp Med Biol. 2012;747:1-18. doi: 10.1007/978-1-4614-3229-6_1. Review.

PMID:
22949108
44.

Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex.

Dastmalchi S, Wilkinson-White L, Kwan AH, Gamsjaeger R, Mackay JP, Matthews JM.

Protein Sci. 2012 Nov;21(11):1768-74. doi: 10.1002/pro.2153. Epub 2012 Sep 25.

45.

Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions.

Bhati M, Lee C, Gadd MS, Jeffries CM, Kwan A, Whitten AE, Trewhella J, Mackay JP, Matthews JM.

PLoS One. 2012;7(7):e40719. doi: 10.1371/journal.pone.0040719. Epub 2012 Jul 25.

46.

Knockdown of the cellular protein LRPPRC attenuates HIV-1 infection.

Schweitzer CJ, Matthews JM, Madson CJ, Donnellan MR, Cerny RL, Belshan M.

PLoS One. 2012;7(7):e40537. doi: 10.1371/journal.pone.0040537. Epub 2012 Jul 12.

47.

Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.

Cubeddu L, Joseph S, Richard DJ, Matthews JM.

PLoS One. 2012;7(6):e39218. doi: 10.1371/journal.pone.0039218. Epub 2012 Jun 19.

48.

Modular assembly of RanBP2-type zinc finger domains to target single-stranded RNA.

O'Connell MR, Vandevenne M, Nguyen CD, Matthews JM, Gamsjaeger R, Segal DJ, Mackay JP.

Angew Chem Int Ed Engl. 2012 May 29;51(22):5371-5. doi: 10.1002/anie.201200866. Epub 2012 Apr 19. No abstract available.

49.

Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses.

Hauswirth R, Haase B, Blatter M, Brooks SA, Burger D, Drögemüller C, Gerber V, Henke D, Janda J, Jude R, Magdesian KG, Matthews JM, Poncet PA, Svansson V, Tozaki T, Wilkinson-White L, Penedo MC, Rieder S, Leeb T.

PLoS Genet. 2012;8(4):e1002653. doi: 10.1371/journal.pgen.1002653. Epub 2012 Apr 12.

50.

Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants.

Hsieh YS, Wilkinson BL, O'Connell MR, Mackay JP, Matthews JM, Payne RJ.

Org Lett. 2012 Apr 6;14(7):1910-3. doi: 10.1021/ol300557g. Epub 2012 Mar 28.

PMID:
22455748

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