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Items: 39

1.

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.

Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW.

Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581.

2.

HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia.

Mehdipour P, Santoro F, Botrugno OA, Romanenghi M, Pagliuca C, Matthews GM, Johnstone RW, Minucci S.

Leukemia. 2017 Apr;31(4):995-997. doi: 10.1038/leu.2017.3. Epub 2017 Jan 24. No abstract available.

PMID:
28074065
3.

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NN, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J.

Cancer Cell. 2016 Sep 12;30(3):499-500. doi: 10.1016/j.ccell.2016.08.009. Epub 2016 Sep 12. No abstract available.

4.

NF-κB dysregulation in multiple myeloma.

Matthews GM, de Matos Simoes R, Dhimolea E, Sheffer M, Gandolfi S, Dashevsky O, Sorrell JD, Mitsiades CS.

Semin Cancer Biol. 2016 Aug;39:68-76. doi: 10.1016/j.semcancer.2016.08.005. Epub 2016 Aug 17. Review.

PMID:
27544796
5.

A genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity.

Falkenberg KJ, Newbold A, Gould CM, Luu J, Trapani JA, Matthews GM, Simpson KJ, Johnstone RW.

Cell Death Differ. 2016 Jul;23(7):1209-18. doi: 10.1038/cdd.2015.175. Epub 2016 Feb 12.

6.

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NY, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J.

Cancer Cell. 2016 Feb 8;29(2):145-58. doi: 10.1016/j.ccell.2016.01.006. Erratum in: Cancer Cell. 2016 Sep 12;30(3):499-500.

7.

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Matthews GM, Mehdipour P, Cluse LA, Falkenberg KJ, Wang E, Roth M, Santoro F, Vidacs E, Stanley K, House CM, Rusche JR, Vakoc CR, Zuber J, Minucci S, Johnstone RW.

Blood. 2015 Nov 19;126(21):2392-403. doi: 10.1182/blood-2015-03-632984. Epub 2015 Oct 7.

8.

Biomarker-based treatment selection in early-stage rectal cancer to promote organ preservation.

Leong KJ, Beggs A, James J, Morton DG, Matthews GM, Bach SP.

Br J Surg. 2014 Sep;101(10):1299-309. doi: 10.1002/bjs.9571. Epub 2014 Jul 23.

9.

Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers.

Westwood JA, Matthews GM, Shortt J, Faulkner D, Pegram HJ, Duong CP, Chesi M, Bergsagel PL, Sharp LL, Huhn RD, Darcy PK, Johnstone RW, Kershaw MH.

Leuk Res. 2014 Aug;38(8):948-54. doi: 10.1016/j.leukres.2014.05.010. Epub 2014 Jun 2.

PMID:
24934848
10.

The drug vehicle and solvent N-methylpyrrolidone is an immunomodulator and antimyeloma compound.

Shortt J, Hsu AK, Martin BP, Doggett K, Matthews GM, Doyle MA, Ellul J, Jockel TE, Andrews DM, Hogg SJ, Reitsma A, Faulkner D, Bergsagel PL, Chesi M, Heath JK, Denny WA, Thompson PE, Neeson PJ, Ritchie DS, McArthur GA, Johnstone RW.

Cell Rep. 2014 May 22;7(4):1009-19. doi: 10.1016/j.celrep.2014.04.008. Epub 2014 May 9.

11.

Induction of apoptosis by the medium-chain length fatty acid lauric acid in colon cancer cells due to induction of oxidative stress.

Fauser JK, Matthews GM, Cummins AG, Howarth GS.

Chemotherapy. 2013;59(3):214-24. doi: 10.1159/000356067. Epub 2013 Dec 13.

PMID:
24356281
12.

Impact of tissue processing, archiving and enrichment techniques on DNA methylation yield in rectal carcinoma.

Leong KJ, James J, Wen K, Taniere P, Morton DG, Bach SP, Matthews GM.

Exp Mol Pathol. 2013 Dec;95(3):343-9. doi: 10.1016/j.yexmp.2013.10.007. Epub 2013 Oct 23.

PMID:
24161956
13.

Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities.

Newbold A, Matthews GM, Bots M, Cluse LA, Clarke CJ, Banks KM, Cullinane C, Bolden JE, Christiansen AJ, Dickins RA, Miccolo C, Chiocca S, Kral AM, Ozerova ND, Miller TA, Methot JL, Richon VM, Secrist JP, Minucci S, Johnstone RW.

Mol Cancer Ther. 2013 Dec;12(12):2709-21. doi: 10.1158/1535-7163.MCT-13-0626. Epub 2013 Oct 3.

14.

Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk*MYC multiple myeloma.

Matthews GM, Lefebure M, Doyle MA, Shortt J, Ellul J, Chesi M, Banks KM, Vidacs E, Faulkner D, Atadja P, Bergsagel PL, Johnstone RW.

Cell Death Dis. 2013 Sep 12;4:e798. doi: 10.1038/cddis.2013.306.

15.

Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.

Beggs AD, Jones A, Shepherd N, Arnaout A, Finlayson C, Abulafi AM, Morton DG, Matthews GM, Hodgson SV, Tomlinson IP.

PLoS Genet. 2013 May;9(5):e1003488. doi: 10.1371/journal.pgen.1003488. Epub 2013 May 9.

16.

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.

Santoro F, Botrugno OA, Dal Zuffo R, Pallavicini I, Matthews GM, Cluse L, Barozzi I, Senese S, Fornasari L, Moretti S, Altucci L, Pelicci PG, Chiocca S, Johnstone RW, Minucci S.

Blood. 2013 Apr 25;121(17):3459-68. doi: 10.1182/blood-2012-10-461988. Epub 2013 Feb 25.

17.

Intrinsic and extrinsic apoptotic pathway signaling as determinants of histone deacetylase inhibitor antitumor activity.

Matthews GM, Newbold A, Johnstone RW.

Adv Cancer Res. 2012;116:165-97. doi: 10.1016/B978-0-12-394387-3.00005-7. Review.

PMID:
23088871
18.

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.

Mattarollo SR, West AC, Steegh K, Duret H, Paget C, Martin B, Matthews GM, Shortt J, Chesi M, Bergsagel PL, Bots M, Zuber J, Lowe SW, Johnstone RW, Smyth MJ.

Blood. 2012 Oct 11;120(15):3019-29. doi: 10.1182/blood-2012-04-426643. Epub 2012 Aug 28.

19.

Short-chain fatty acids induce apoptosis in colon cancer cells associated with changes to intracellular redox state and glucose metabolism.

Matthews GM, Howarth GS, Butler RN.

Chemotherapy. 2012;58(2):102-9. doi: 10.1159/000335672. Epub 2012 Apr 6.

PMID:
22488147
20.

Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy.

Chesi M, Matthews GM, Garbitt VM, Palmer SE, Shortt J, Lefebure M, Stewart AK, Johnstone RW, Bergsagel PL.

Blood. 2012 Jul 12;120(2):376-85. doi: 10.1182/blood-2012-02-412783. Epub 2012 Mar 26.

21.

Methylation profiling of rectal cancer identifies novel markers of early-stage disease.

Leong KJ, Wei W, Tannahill LA, Caldwell GM, Jones CE, Morton DG, Matthews GM, Bach SP.

Br J Surg. 2011 May;98(5):724-34. doi: 10.1002/bjs.7422. Epub 2011 Feb 24.

PMID:
21360524
22.

Wnt signalling in adenomas of familial adenomatous polyposis patients.

Caldwell GM, Jones CE, Ashley AM, Wei W, Hejmadi RK, Morton DG, Matthews GM.

Br J Cancer. 2010 Sep 7;103(6):910-7. doi: 10.1038/sj.bjc.6605790. Epub 2010 Jul 13.

23.

Reorganisation of Wnt-response pathways in colorectal tumorigenesis.

Caldwell GM, Jones CE, Soon Y, Warrack R, Morton DG, Matthews GM.

Br J Cancer. 2008 Apr 22;98(8):1437-42. doi: 10.1038/sj.bjc.6604327. Epub 2008 Apr 15.

24.

Short-chain fatty acid modulation of apoptosis in the Kato III human gastric carcinoma cell line.

Matthews GM, Howarth GS, Butler RN.

Cancer Biol Ther. 2007 Jul;6(7):1051-7.

PMID:
17611404
25.

Nutrient and antioxidant modulation of apoptosis in gastric and colon cancer cells.

Matthews GM, Howarth GS, Butler RN.

Cancer Biol Ther. 2006 Jun;5(6):569-72. Epub 2006 Jun 2. Review.

PMID:
16760645
26.

The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas.

Caldwell GM, Jones CE, Taniere P, Warrack R, Soon Y, Matthews GM, Morton DG.

Br J Cancer. 2006 Mar 27;94(6):922-7.

27.
28.

13C-urea breath test: reproducibility and association with the severity of Helicobacter pylori-associated antral gastritis.

Matthews GM, Cummins AG, Lawrence A, Johnson B, Campbell F, Butler RN.

J Gastroenterol Hepatol. 2005 Feb;20(2):270-4.

PMID:
15683431
29.

Cellular mucosal defense is attenuated with chronicity of Helicobacter pylori infection.

Matthews GM, Tivey D, Cummins AG, Butler RN.

Dig Dis Sci. 2004 Aug;49(7-8):1109-15.

PMID:
15387330
30.

Stimulation of small intestinal burst activity in the postprandial state differentially affects lipid and glucose absorption in healthy adult humans.

Bryant LK, Fraser RJ, Vozzo R, Zacharakis B, Matthews GM, Butler R.

Am J Physiol Gastrointest Liver Physiol. 2004 Nov;287(5):G1028-34. Epub 2004 Jun 10.

31.

The Wnt antagonist sFRP1 in colorectal tumorigenesis.

Caldwell GM, Jones C, Gensberg K, Jan S, Hardy RG, Byrd P, Chughtai S, Wallis Y, Matthews GM, Morton DG.

Cancer Res. 2004 Feb 1;64(3):883-8.

32.

Effect of adenosine on CO2 chemosensitivity. Functional, cellular, and molecular studies.

Kumar P, Conway AF, Vandier C, Marshall NJ, Bruynseels J, Matthews GM.

Adv Exp Med Biol. 2000;475:405-10. No abstract available.

PMID:
10849680
33.

The Xenopus egg extract translation system.

Matthews GM, Colman A.

Methods Mol Biol. 1998;86:235-47. No abstract available.

PMID:
9664475
34.

Subtilisin-related serine proteases in the mammalian constitutive secretory pathway.

Gensberg K, Jan S, Matthews GM.

Semin Cell Dev Biol. 1998 Feb;9(1):11-7. Review.

PMID:
9572109
35.

Polarised membrane traffic in hepatocytes.

Wilton JC, Matthews GM.

Bioessays. 1996 Mar;18(3):229-36. Review.

PMID:
8867737
36.

The Xenopus egg extract translation system.

Matthews GM, Colman A.

Methods Mol Biol. 1995;37:199-213. No abstract available.

PMID:
7780505
37.
38.

Control in vitro of tocopherol oxidase by light and by auxins, kinetin, gibberellic acid, abscisic acid and ethylene [proceedings].

Gaunt JK, Matthews GM, Plumpton ES.

Biochem Soc Trans. 1980 Apr;8(2):186-7. No abstract available.

PMID:
6445302
39.

STAFF LIBRARY SERVICES IN SCHOOLS FOR THE MENTALLY RETARDED.

MATTHEWS GM.

Ment Retard. 1963 Aug;1(4):252-6. No abstract available.

PMID:
14058529

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