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Items: 1 to 50 of 121

1.

Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice.

Morton SK, Chaston DJ, Howitt L, Heisler J, Nicholson BJ, Fairweather S, Bröer S, Ashton AW, Matthaei KI, Hill CE.

Hypertension. 2015 Mar;65(3):662-9. doi: 10.1161/HYPERTENSIONAHA.114.04578. Epub 2014 Dec 29.

PMID:
25547341
2.

Dual proinflammatory and antiviral properties of pulmonary eosinophils in respiratory syncytial virus vaccine-enhanced disease.

Su YC, Townsend D, Herrero LJ, Zaid A, Rolph MS, Gahan ME, Nelson MA, Rudd PA, Matthaei KI, Foster PS, Dent L, Tripp RA, Lee J, Simson L, Mahalingam S.

J Virol. 2015 Feb;89(3):1564-78. doi: 10.1128/JVI.01536-14. Epub 2014 Nov 19.

3.

Perturbation of chemical coupling by an endothelial Cx40 mutant attenuates endothelium-dependent vasodilation by KCa channels and elevates blood pressure in mice.

Chaston DJ, Haddock RE, Howitt L, Morton SK, Brown RD, Matthaei KI, Hill CE.

Pflugers Arch. 2015 Sep;467(9):1997-2009. doi: 10.1007/s00424-014-1640-x. Epub 2014 Nov 5.

PMID:
25369777
4.

Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit.

Howitt L, Matthaei KI, Drummond GR, Hill CE.

Pflugers Arch. 2015 Apr;467(4):727-35. doi: 10.1007/s00424-014-1548-5. Epub 2014 Jun 14.

PMID:
24923576
5.

The kinematics of cytotoxic lymphocytes influence their ability to kill target cells.

Bhat P, Leggatt G, Matthaei KI, Frazer IH.

PLoS One. 2014 May 6;9(5):e95248. doi: 10.1371/journal.pone.0095248. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e101381.

6.

Regulation of endothelial-specific transgene expression by the LacI repressor protein in vivo.

Morton SK, Chaston DJ, Baillie BK, Hill CE, Matthaei KI.

PLoS One. 2014 Apr 22;9(4):e95980. doi: 10.1371/journal.pone.0095980. eCollection 2014.

7.

Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation.

Poon IK, Goodall KJ, Phipps S, Chow JD, Pagler EB, Andrews DM, Conlan CL, Ryan GF, White JA, Wong MK, Horan C, Matthaei KI, Smyth MJ, Hulett MD.

Eur J Immunol. 2014 Apr;44(4):1016-30. doi: 10.1002/eji.201343645. Epub 2014 Feb 14.

8.

Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties.

Frese M, Lee E, Larena M, Lim PS, Rao S, Matthaei KI, Khromykh A, Ramshaw I, Lobigs M.

J Virol. 2014 Feb;88(4):2056-70. doi: 10.1128/JVI.03051-13. Epub 2013 Dec 4.

9.

Teratoma formation in immunocompetent mice after syngeneic and allogeneic implantation of germline capable mouse embryonic stem cells.

Aldahmash A, Atteya M, Elsafadi M, Al-Nbaheen M, Al-Mubarak HA, Vishnubalaji R, Al-Roalle A, Al-Harbi S, Manikandan M, Matthaei KI, Mahmood A.

Asian Pac J Cancer Prev. 2013;14(10):5705-11.

10.

Molecular pathways involved in the improvement of non-alcoholic fatty liver disease.

Paz-Filho G, Mastronardi CA, Parker BJ, Khan A, Inserra A, Matthaei KI, Ehrhart-Bornstein M, Bornstein S, Wong ML, Licinio J.

J Mol Endocrinol. 2013 Jun 29;51(1):167-79. doi: 10.1530/JME-13-0072. Print 2013.

PMID:
23718963
11.

Polymorphism in endothelial connexin40 enhances sensitivity to intraluminal pressure and increases arterial stiffness.

Chaston DJ, Baillie BK, Grayson TH, Courjaret RJ, Heisler JM, Lau KA, Machaca K, Nicholson BJ, Ashton A, Matthaei KI, Hill CE.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):962-70. doi: 10.1161/ATVBAHA.112.300957. Epub 2013 Mar 7.

PMID:
23471232
12.

Spreading vasodilatation in the murine microcirculation: attenuation by oxidative stress-induced change in electromechanical coupling.

Howitt L, Chaston DJ, Sandow SL, Matthaei KI, Edwards FR, Hill CE.

J Physiol. 2013 Apr 15;591(8):2157-73. doi: 10.1113/jphysiol.2013.250928. Epub 2013 Feb 25.

13.

The human parasite Loa loa in cytokine and cytokine receptor gene knock out BALB/c mice: survival, development and localization.

Tendongfor N, Wanji S, Ngwa JC, Esum ME, Specht S, Enyong P, Matthaei KI, Hoerauf A.

Parasit Vectors. 2012 Feb 21;5:43. doi: 10.1186/1756-3305-5-43.

14.

The impact of glutathione transferase kappa deficiency on adiponectin multimerisation in vivo.

Theodoratos A, Blackburn AC, Coggan M, Cappello J, Larter CZ, Matthaei KI, Board PG.

Int J Obes (Lond). 2012 Oct;36(10):1366-9. doi: 10.1038/ijo.2011.267. Epub 2012 Jan 17.

PMID:
22249229
15.

Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle.

Barrientos GC, Feng W, Truong K, Matthaei KI, Yang T, Allen PD, Lopez JR, Pessah IN.

J Biol Chem. 2012 Jan 20;287(4):2863-76. doi: 10.1074/jbc.M111.307926. Epub 2011 Dec 2.

16.

Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.

Yuen B, Boncompagni S, Feng W, Yang T, Lopez JR, Matthaei KI, Goth SR, Protasi F, Franzini-Armstrong C, Allen PD, Pessah IN.

FASEB J. 2012 Mar;26(3):1311-22. doi: 10.1096/fj.11-197582. Epub 2011 Nov 30.

17.

Glutathione transferase kappa deficiency causes glomerular nephropathy without overt oxidative stress.

Blackburn AC, Coggan M, Shield AJ, Cappello J, Theodoratos A, Murray TP, Rooke M, Larter CZ, Koina ME, Dahlstrom JE, Matthaei KI, Board PG.

Lab Invest. 2011 Nov;91(11):1572-83. doi: 10.1038/labinvest.2011.107. Epub 2011 Aug 8.

18.

Mouse strains for the ubiquitous or conditional overexpression of the Flii gene.

Thomsen N, Chappell A, Ali RG, Jones T, Adams DH, Matthaei KI, Campbell HD, Cowin AJ, Arkell RM.

Genesis. 2011 Aug;49(8):681-8. doi: 10.1002/dvg.20735. Epub 2011 Jul 22.

PMID:
21786402
19.

Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway.

Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, Foo SY, Hansbro N, Uematsu S, Akira S, Matthaei KI, Rosenberg HF, Foster PS, Phipps S.

J Immunol. 2011 May 15;186(10):5938-48. doi: 10.4049/jimmunol.1002635. Epub 2011 Apr 11.

20.

Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?

Matthaei KI, Frese M, Hill CE.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):E43; author reply E44. doi: 10.1073/pnas.1100419108. Epub 2011 Mar 14. No abstract available.

21.

Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.

Wu D, Ahrens R, Osterfeld H, Noah TK, Groschwitz K, Foster PS, Steinbrecher KA, Rothenberg ME, Shroyer NF, Matthaei KI, Finkelman FD, Hogan SP.

J Biol Chem. 2011 Apr 15;286(15):13357-69. doi: 10.1074/jbc.M110.214965. Epub 2011 Feb 8.

22.

Evaluating vaccinia virus cytokine co-expression in TLR GKO mice.

Sutherland DB, Ranasinghe C, Regner M, Phipps S, Matthaei KI, Day SL, Ramshaw IA.

Immunol Cell Biol. 2011 Aug;89(6):706-15. doi: 10.1038/icb.2010.157. Epub 2010 Dec 21.

PMID:
21173782
23.

Expression of distinct RNAs from 3' untranslated regions.

Mercer TR, Wilhelm D, Dinger ME, Soldà G, Korbie DJ, Glazov EA, Truong V, Schwenke M, Simons C, Matthaei KI, Saint R, Koopman P, Mattick JS.

Nucleic Acids Res. 2011 Mar;39(6):2393-403. doi: 10.1093/nar/gkq1158. Epub 2010 Nov 12.

24.

In vivo modulation of angiogenesis by beta 2 glycoprotein I.

Passam FH, Qi JC, Tanaka K, Matthaei KI, Krilis SA.

J Autoimmun. 2010 Nov;35(3):232-40. doi: 10.1016/j.jaut.2010.06.013. Epub 2010 Jul 24.

PMID:
20655705
25.

Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene.

Qiu MR, Jiang L, Matthaei KI, Schoenwaelder SM, Kuffner T, Mangin P, Joseph JE, Low J, Connor D, Valenzuela SM, Curmi PM, Brown LJ, Mahaut-Smith M, Jackson SP, Breit SN.

Genesis. 2010 Feb;48(2):127-36. doi: 10.1002/dvg.20590. Erratum in: Genesis. 2010 May;48(5):351.

PMID:
20049953
26.

Allergic sensitization is enhanced in early life through toll-like receptor 7 activation.

Phipps S, Hansbro N, Lam CE, Foo SY, Matthaei KI, Foster PS.

Clin Exp Allergy. 2009 Dec;39(12):1920-8. doi: 10.1111/j.1365-2222.2009.03335.x. Epub 2009 Sep 3.

PMID:
19735273
27.

The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance to the nematodes Nippostrongylus brasiliensis and Heligmosomoides bakeri.

Knott ML, Matthaei KI, Foster PS, Dent LA.

Mol Immunol. 2009 Aug;46(13):2714-22. doi: 10.1016/j.molimm.2009.05.016. Epub 2009 Jun 16.

PMID:
19535141
28.

Identification of therapeutic drug targets through genetically manipulated mice: are we getting it right?

Matthaei KI.

Pharmacol Ther. 2009 Jul;123(1):32-6. doi: 10.1016/j.pharmthera.2009.03.016. Epub 2009 Apr 15.

PMID:
19375454
29.

Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses.

Phipps S, Lam CE, Kaiko GE, Foo SY, Collison A, Mattes J, Barry J, Davidson S, Oreo K, Smith L, Mansell A, Matthaei KI, Foster PS.

Am J Respir Crit Care Med. 2009 May 15;179(10):883-93. doi: 10.1164/rccm.200806-974OC. Epub 2009 Feb 26. Erratum in: Am J Respir Crit Care Med. 2009 Nov 15;180(10):1032.

PMID:
19246719
30.

FVB/N mice are highly resistant to primary infection with Nippostrongylus brasiliensis.

Knott ML, Hogan SP, Wang H, Matthaei KI, Dent LA.

Parasitology. 2009 Jan;136(1):93-106. doi: 10.1017/S0031182008005192.

31.

Integrated research into the nanoparticle-protein corona: a new focus for safe, sustainable and equitable development of nanomedicines.

Faunce TA, White J, Matthaei KI.

Nanomedicine (Lond). 2008 Dec;3(6):859-66. doi: 10.2217/17435889.3.6.859. Review.

PMID:
19025459
32.

IL-5-overexpressing mice exhibit eosinophilia and altered wound healing through mechanisms involving prolonged inflammation.

Leitch VD, Strudwick XL, Matthaei KI, Dent LA, Cowin AJ.

Immunol Cell Biol. 2009 Feb;87(2):131-40. doi: 10.1038/icb.2008.72. Epub 2008 Oct 7.

PMID:
18839016
33.

Molecular and cellular mechanisms in the viral exacerbation of asthma.

Tauro S, Su YC, Thomas S, Schwarze J, Matthaei KI, Townsend D, Simson L, Tripp RA, Mahalingam S.

Microbes Infect. 2008 Jul;10(9):1014-23. doi: 10.1016/j.micinf.2008.07.037. Epub 2008 Aug 13. Review.

PMID:
18762266
34.

IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.

Forbes EE, Groschwitz K, Abonia JP, Brandt EB, Cohen E, Blanchard C, Ahrens R, Seidu L, McKenzie A, Strait R, Finkelman FD, Foster PS, Matthaei KI, Rothenberg ME, Hogan SP.

J Exp Med. 2008 Apr 14;205(4):897-913. doi: 10.1084/jem.20071046. Epub 2008 Mar 31.

35.

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer.

Quah BJ, Barlow VP, McPhun V, Matthaei KI, Hulett MD, Parish CR.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4259-64. doi: 10.1073/pnas.0800259105. Epub 2008 Mar 12. Erratum in: Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14734.

36.

Gender specific effects on the actin-remodelling protein Flightless I and TGF-beta1 contribute to impaired wound healing in aged skin.

Adams DH, Strudwick XL, Kopecki Z, Hooper-Jones JA, Matthaei KI, Campbell HD, Powell BC, Cowin AJ.

Int J Biochem Cell Biol. 2008;40(8):1555-69. doi: 10.1016/j.biocel.2007.11.024. Epub 2007 Dec 8.

PMID:
18191609
37.

Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease.

Weckmann M, Collison A, Simpson JL, Kopp MV, Wark PA, Smyth MJ, Yagita H, Matthaei KI, Hansbro N, Whitehead B, Gibson PG, Foster PS, Mattes J.

Nat Med. 2007 Nov;13(11):1308-15. Epub 2007 Oct 14.

PMID:
17934471
38.

The contribution of toll-like receptors to the pathogenesis of asthma.

Phipps S, Lam CE, Foster PS, Matthaei KI.

Immunol Cell Biol. 2007 Aug-Sep;85(6):463-70. Epub 2007 Aug 7. Review.

PMID:
17680012
39.

Impaired resistance in early secondary Nippostrongylus brasiliensis infections in mice with defective eosinophilopoeisis.

Knott ML, Matthaei KI, Giacomin PR, Wang H, Foster PS, Dent LA.

Int J Parasitol. 2007 Oct;37(12):1367-78. Epub 2007 May 4.

PMID:
17555758
40.

Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus.

Phipps S, Lam CE, Mahalingam S, Newhouse M, Ramirez R, Rosenberg HF, Foster PS, Matthaei KI.

Blood. 2007 Sep 1;110(5):1578-86. Epub 2007 May 10.

PMID:
17495130
41.

Genetically manipulated mice: a powerful tool with unsuspected caveats.

Matthaei KI.

J Physiol. 2007 Jul 15;582(Pt 2):481-8. Epub 2007 May 10. Review.

42.

Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance.

Simson L, Ellyard JI, Dent LA, Matthaei KI, Rothenberg ME, Foster PS, Smyth MJ, Parish CR.

J Immunol. 2007 Apr 1;178(7):4222-9.

43.

Flightless I deficiency enhances wound repair by increasing cell migration and proliferation.

Cowin AJ, Adams DH, Strudwick XL, Chan H, Hooper JA, Sander GR, Rayner TE, Matthaei KI, Powell BC, Campbell HD.

J Pathol. 2007 Apr;211(5):572-81.

PMID:
17326236
44.

Comparative roles of IL-4, IL-13, and IL-4Ralpha in dendritic cell maturation and CD4+ Th2 cell function.

Webb DC, Cai Y, Matthaei KI, Foster PS.

J Immunol. 2007 Jan 1;178(1):219-27.

45.

Mechanism of interleukin-25 (IL-17E)-induced pulmonary inflammation and airways hyper-reactivity.

Sharkhuu T, Matthaei KI, Forbes E, Mahalingam S, Hogan SP, Hansbro PM, Foster PS.

Clin Exp Allergy. 2006 Dec;36(12):1575-83.

PMID:
17177681
46.

Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.

Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR.

Anesthesiology. 2006 Dec;105(6):1164-75.

PMID:
17122579
47.

Inhibition of arginase I activity by RNA interference attenuates IL-13-induced airways hyperresponsiveness.

Yang M, Rangasamy D, Matthaei KI, Frew AJ, Zimmmermann N, Mahalingam S, Webb DC, Tremethick DJ, Thompson PJ, Hogan SP, Rothenberg ME, Cowden WB, Foster PS.

J Immunol. 2006 Oct 15;177(8):5595-603.

48.

Gz proteins are functionally coupled to dopamine D2-like receptors in vivo.

Leck KJ, Blaha CD, Matthaei KI, Forster GL, Holgate J, Hendry IA.

Neuropharmacology. 2006 Sep;51(3):597-605. Epub 2006 Jun 30.

PMID:
16814816
49.

ICAM-1-dependent pathways regulate colonic eosinophilic inflammation.

Forbes E, Hulett M, Ahrens R, Wagner N, Smart V, Matthaei KI, Brandt EB, Dent LA, Rothenberg ME, Tang M, Foster PS, Hogan SP.

J Leukoc Biol. 2006 Aug;80(2):330-41. Epub 2006 May 26.

PMID:
16731772
50.

Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways.

Blackburn AC, Matthaei KI, Lim C, Taylor MC, Cappello JY, Hayes JD, Anders MW, Board PG.

Mol Pharmacol. 2006 Feb;69(2):650-7. Epub 2005 Nov 8.

PMID:
16278372

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