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Items: 14


ESR and X-ray Structure Investigations on the Binding and Mechanism of Inhibition of the Native State of Myeloperoxidase with Low Molecular Weight Fragments.

Chavali B, Masquelin T, Nilges MJ, Timm DE, Stout SL, Matter WF, Jin N, Jadhav PK, Deng GG.

Appl Magn Reson. 2015;46(8):853-873. Epub 2015 May 19.


Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm.

Jadhav PK, Schiffler MA, Gavardinas K, Kim EJ, Matthews DP, Staszak MA, Coffey DS, Shaw BW, Cassidy KC, Brier RA, Zhang Y, Christie RM, Matter WF, Qing K, Durbin JD, Wang Y, Deng GG.

ACS Med Chem Lett. 2014 Aug 27;5(10):1138-42. doi: 10.1021/ml500283g. eCollection 2014 Oct 9.


Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA.

Wang X, Mader MM, Toth JE, Yu X, Jin N, Campbell RM, Smallwood JK, Christe ME, Chatterjee A, Goodson T Jr, Vlahos CJ, Matter WF, Bloem LJ.

J Biol Chem. 2005 May 13;280(19):19298-305. Epub 2005 Feb 28.


Effect of drotrecogin alfa (activated) on human endothelial cell permeability and Rho kinase signaling.

Zeng W, Matter WF, Yan SB, Um SL, Vlahos CJ, Liu L.

Crit Care Med. 2004 May;32(5 Suppl):S302-8.


Phosphoinositide 3-kinase regulates excitation-contraction coupling in neonatal cardiomyocytes.

McDowell SA, McCall E, Matter WF, Estridge TB, Vlahos CJ.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H796-805. Epub 2003 Oct 16.


Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling.

Matter WF, Estridge T, Zhang C, Belagaje R, Stancato L, Dixon J, Johnson B, Bloem L, Pickard T, Donaghue M, Acton S, Jeyaseelan R, Kadambi V, Vlahos CJ.

Biochem Biophys Res Commun. 2001 May 25;283(5):1061-8.


Calmodulin activates phosphatidylinositol 3-kinase.

Joyal JL, Burks DJ, Pons S, Matter WF, Vlahos CJ, White MF, Sacks DB.

J Biol Chem. 1997 Nov 7;272(45):28183-6.


LY295427, a novel hypocholesterolemic agent, enhances [3H]25-hydroxycholesterol binding to liver cytosolic proteins.

Bowling N, Matter WF, Gadski RA, McClure DB, Schreyer T, Dawson PA, Vlahos CJ.

J Lipid Res. 1996 Dec;37(12):2586-98.


Effects of wortmannin analogs on bone in vitro and in vivo.

Sato M, Bryant HU, Dodge JA, Davis H, Matter WF, Vlahos CJ.

J Pharmacol Exp Ther. 1996 Apr;277(1):543-50.


Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase.

Vlahos CJ, Matter WF, Brown RF, Traynor-Kaplan AE, Heyworth PG, Prossnitz ER, Ye RD, Marder P, Schelm JA, Rothfuss KJ, et al.

J Immunol. 1995 Mar 1;154(5):2413-22.


Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.

Powis G, Bonjouklian R, Berggren MM, Gallegos A, Abraham R, Ashendel C, Zalkow L, Matter WF, Dodge J, Grindey G, et al.

Cancer Res. 1994 May 1;54(9):2419-23.


The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs.

Matter WF, Brown RF, Vlahos CJ.

Biochem Biophys Res Commun. 1992 Jul 31;186(2):624-31.


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