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Items: 1 to 50 of 210

1.

Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion.

Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S.

Cell Chem Biol. 2018 Dec 20;25(12):1519-1532.e5. doi: 10.1016/j.chembiol.2018.09.012. Epub 2018 Oct 18.

PMID:
30344053
2.
3.

A systematic analysis of acceptor specificity and reaction kinetics of five human α(2,3)sialyltransferases: Product inhibition studies illustrate reaction mechanism for ST3Gal-I.

Gupta R, Matta KL, Neelamegham S.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):606-12. doi: 10.1016/j.bbrc.2015.11.130. Epub 2015 Dec 13.

4.

Identification and Biochemical Characterization of the Novel α2,3-Sialyltransferase WbwA from Pathogenic Escherichia coli Serotype O104.

Czuchry D, Desormeaux P, Stuart M, Jarvis DL, Matta KL, Szarek WA, Brockhausen I.

J Bacteriol. 2015 Dec;197(24):3760-8. doi: 10.1128/JB.00521-15. Epub 2015 Sep 21.

5.

Enhancing MS(n) mass spectrometry strategy for carbohydrate analysis: A b2 ion spectral library.

Xue J, Laine RA, Matta KL.

J Proteomics. 2015 Jan 1;112:224-49. doi: 10.1016/j.jprot.2014.07.013. Epub 2014 Aug 29.

PMID:
25175058
6.

Overexpression of α2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis.

Patil SA, Bshara W, Morrison C, Chandrasekaran EV, Matta KL, Neelamegham S.

Glycoconj J. 2014 Oct;31(6-7):509-21. doi: 10.1007/s10719-014-9548-4.

7.

Acceptor specificities and selective inhibition of recombinant human Gal- and GlcNAc-transferases that synthesize core structures 1, 2, 3 and 4 of O-glycans.

Gao Y, Aryal RP, Ju T, Cummings RD, Gahlay G, Jarvis DL, Matta KL, Vlahakis JZ, Szarek WA, Brockhausen I.

Biochim Biophys Acta. 2013 Aug;1830(8):4274-81. doi: 10.1016/j.bbagen.2013.04.001. Epub 2013 Apr 8.

8.

Scaling down the size and increasing the throughput of glycosyltransferase assays: activity changes on stem cell differentiation.

Patil SA, Chandrasekaran EV, Matta KL, Parikh A, Tzanakakis ES, Neelamegham S.

Anal Biochem. 2012 Jun 15;425(2):135-44. doi: 10.1016/j.ab.2012.03.009. Epub 2012 Mar 23.

9.

Characterization of cancer associated mucin type O-glycans using the exchange sialylation properties of mammalian sialyltransferase ST3Gal-II.

Chandrasekaran EV, Xue J, Xia J, Locke RD, Patil SA, Neelamegham S, Matta KL.

J Proteome Res. 2012 Apr 6;11(4):2609-18. doi: 10.1021/pr201108q. Epub 2012 Feb 29.

10.

Metabolic inhibition of galectin-1-binding carbohydrates accentuates antitumor immunity.

Cedeno-Laurent F, Opperman MJ, Barthel SR, Hays D, Schatton T, Zhan Q, He X, Matta KL, Supko JG, Frank MH, Murphy GF, Dimitroff CJ.

J Invest Dermatol. 2012 Feb;132(2):410-20. doi: 10.1038/jid.2011.335. Epub 2011 Dec 8.

11.

Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides.

Chandrasekaran EV, Xue J, Xia J, Locke RD, Patil SA, Neelamegham S, Matta KL.

Biochemistry. 2011 Nov 8;50(44):9475-87. doi: 10.1021/bi200301w. Epub 2011 Oct 13.

12.

Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.

Barthel SR, Antonopoulos A, Cedeno-Laurent F, Schaffer L, Hernandez G, Patil SA, North SJ, Dell A, Matta KL, Neelamegham S, Haslam SM, Dimitroff CJ.

J Biol Chem. 2011 Jun 17;286(24):21717-31. doi: 10.1074/jbc.M110.194597. Epub 2011 Apr 14.

13.
15.

Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation.

Nasirikenari M, Chandrasekaran EV, Matta KL, Segal BH, Bogner PN, Lugade AA, Thanavala Y, Lee JJ, Lau JT.

J Leukoc Biol. 2010 Mar;87(3):457-66. doi: 10.1189/jlb.1108704. Epub 2009 Dec 9.

16.

Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins.

Marathe DD, Buffone A Jr, Chandrasekaran EV, Xue J, Locke RD, Nasirikenari M, Lau JT, Matta KL, Neelamegham S.

Blood. 2010 Feb 11;115(6):1303-12. doi: 10.1182/blood-2009-07-231480. Epub 2009 Dec 8.

17.

Systems-level modeling of cellular glycosylation reaction networks: O-linked glycan formation on natural selectin ligands.

Liu G, Marathe DD, Matta KL, Neelamegham S.

Bioinformatics. 2008 Dec 1;24(23):2740-7. doi: 10.1093/bioinformatics/btn515. Epub 2008 Oct 7.

18.

Systems-level studies of glycosyltransferase gene expression and enzyme activity that are associated with the selectin binding function of human leukocytes.

Marathe DD, Chandrasekaran EV, Lau JT, Matta KL, Neelamegham S.

FASEB J. 2008 Dec;22(12):4154-67. doi: 10.1096/fj.07-104257. Epub 2008 Aug 20.

20.

Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.

Chandrasekaran EV, Xue J, Piskorz C, Locke RD, Tóth K, Slocum HK, Matta KL.

J Cancer Res Clin Oncol. 2007 Sep;133(9):599-611. Epub 2007 May 11.

PMID:
17492468
21.

Quantitative measurement of selectin-ligand interactions: assays to identify a sweet pill in a library of carbohydrates.

Beauharnois ME, Neelamegham S, Matta KL.

Methods Mol Biol. 2006;347:343-58. Review.

PMID:
17072022
22.
24.

Molecular characterization of a novel UDP-galactose:fucoside alpha3-galactosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium.

Ercan A, Panico M, Sutton-Smith M, Dell A, Morris HR, Matta KL, Gay DF, West CM.

J Biol Chem. 2006 May 5;281(18):12713-21. Epub 2006 Feb 22.

26.

Affinity and kinetics of sialyl Lewis-X and core-2 based oligosaccharides binding to L- and P-selectin.

Beauharnois ME, Lindquist KC, Marathe D, Vanderslice P, Xia J, Matta KL, Neelamegham S.

Biochemistry. 2005 Jul 12;44(27):9507-19.

PMID:
15996105
27.

Determination of linkage position and anomeric configuration in Hex-Fuc disaccharides using electrospray ionization tandem mass spectrometry.

Xue J, Song L, Khaja SD, Locke RD, West CM, Laine RA, Matta KL.

Rapid Commun Mass Spectrom. 2004;18(17):1947-55.

PMID:
15329861
28.

Specificity of a soluble UDP-galactose: fucoside alpha1,3-galactosyltransferase that modifies the cytoplasmic glycoprotein Skp1 in Dictyostelium.

Ketcham C, Wang F, Fisher SZ, Ercan A, van der Wel H, Locke RD, Sirajud-Doulah K, Matta KL, West CM.

J Biol Chem. 2004 Jul 9;279(28):29050-9. Epub 2004 May 3.

31.

Biologic contribution of P1 promoter-mediated expression of ST6Gal I sialyltransferase.

Appenheimer MM, Huang RY, Chandrasekaran EV, Dalziel M, Hu YP, Soloway PD, Wuensch SA, Matta KL, Lau JT.

Glycobiology. 2003 Aug;13(8):591-600. Epub 2003 Apr 2.

PMID:
12672700
32.

Complex oligosaccharide investigations: synthesis of an octasaccharide incorporating the dimeric Le(x) structure of PSGL-1.

Xia J, Alderfer JL, Locke RD, Piskorz CF, Matta KL.

J Org Chem. 2003 Apr 4;68(7):2752-9.

PMID:
12662048
33.

A convergent synthesis of core 2 branched sialylated and sulfated oligosaccharides.

Xia J, Alderfer JL, Srikrishnan T, Chandrasekaran EV, Matta KL.

Bioorg Med Chem. 2002 Nov;10(11):3673-84.

PMID:
12213483
34.

Liposomes containing ligands. Binding specificity to selectins.

Neelamegham S, Matta KL.

Methods Mol Biol. 2002;199:175-91. Review. No abstract available.

PMID:
12094569
35.

High-affinity binding of recombinant human galectin-4 to SO(3)(-)-->3Galbeta1-->3GalNAc pyranoside.

Ideo H, Seko A, Ohkura T, Matta KL, Yamashita K.

Glycobiology. 2002 Mar;12(3):199-208.

PMID:
11971864
36.
37.

Tumor cells as the origin of elevated serum alpha1,3fucosyltransferase in association with malignancy.

Asao T, Kuwano H, Nakamura J, Okamura A, Berger EG, Matta KL, Yazawa S.

Clin Exp Metastasis. 2000;18(7):605-10.

PMID:
11688966
38.

Human ovarian cancer, lymphoma spleen, and bovine milk GlcNAc:beta1,4Gal/GalNAc transferases: two molecular species in ovarian tumor and induction of GalNAcbeta1,4Glc synthesis by alpha-lactalbumin.

Chandrasekaran EV, Chawda R, Piskorz C, Locke RD, Ta A, Sharad G, Odunsi K, Lele S, Matta KL.

Carbohydr Res. 2001 Aug 23;334(2):105-18.

PMID:
11502266
40.
41.

A new method for assaying adhesion of cancer cells to the greater omentum and its application for evaluating anti-adhesion activities of chemically synthesized oligosaccharides.

Okamura A, Yazawa S, Nishimura T, Tanaka S, Takai I, Kudo S, Asao T, Kuwano H, Matta KL, Akamatsu S, Kochibe N.

Clin Exp Metastasis. 2000;18(1):37-43.

PMID:
11206836
42.

Molecular analysis of plasma alpha 1,3-fucosyltransferase deficiency and development of the methods for its genotyping.

Tanaka S, Yazawa S, Noguchi K, Nishimura T, Miyanaga K, Kochibe N, Poland DC, Van Dijk W, Matta KL.

Exp Clin Immunogenet. 2001;18(1):1-12.

PMID:
11150848
43.

Chemical synthesis of sulfated oligosaccharides with a beta-D-Gal-(1-->3).

Xia J, Srikrishnan T, Alderfer JL, Jain RK, Piskorz CF, Matta KL.

Carbohydr Res. 2000 Nov 17;329(3):561-77.

PMID:
11128585
44.

Chemical synthesis of a core 2 branched pentasaccharide containing a carboxylate group.

Xia J, Alderfer JL, Matta KL.

Bioorg Med Chem Lett. 2000 Nov 6;10(21):2485-7.

PMID:
11078206
45.

Total synthesis of sialylated and sulfated oligosaccharide chains from respiratory mucins.

Xia J, Alderfer JL, Piskorz CF, Matta KL.

Chemistry. 2000 Sep 15;6(18):3442-51.

PMID:
11039538
46.
47.

Characterization of distinct Gal:3-O-sulfotransferase activities in human tumor epithelial cell lines and of calf lymph node GlcNAc : 6-O-sulfotransferase activity.

Chandrasekaran EV, Jain RK, Rhodes JM, Chawda R, Piskorz C, Matta KL.

Glycoconj J. 1999 Sep;16(9):523-36.

PMID:
10815989
48.

N-p-nitrobenzyloxycarbonyl galactosamine imidate as a glycosyl donor for the efficient synthesis of mucin core-2 analogue.

Liao W, Piskorz CF, Locke RD, Matta KL.

Bioorg Med Chem Lett. 2000 Apr 17;10(8):793-5.

PMID:
10782688
49.

Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules.

Moloney DJ, Shair LH, Lu FM, Xia J, Locke R, Matta KL, Haltiwanger RS.

J Biol Chem. 2000 Mar 31;275(13):9604-11.

50.

An efficient synthesis of two monosulfated trisaccharides with the Galbeta1,3GlcNacbeta1,3Galbeta-O-allyl backbone.

Xia J, Piskorz CF, Locke RD, Chandrasekaran EV, Alderfer JL, Matta KL.

Bioorg Med Chem Lett. 1999 Oct 18;9(20):2941-6.

PMID:
10571152

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