Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 250


PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis.

Wu W, Zhou G, Han H, Huang X, Jiang H, Mukai S, Kazlauskas A, Cui J, Matsubara JA, Vanhaesebroeck B, Xia X, Wang J, Lei H.

Diabetes. 2020 Jan 8. pii: db190713. doi: 10.2337/db19-0713. [Epub ahead of print]


Idelalisib inhibits vitreous-induced Akt activation and proliferation of retinal pigment epithelial cells from epiretinal membranes.

Xin T, Han H, Wu W, Huang X, Cui J, Matsubara JA, Song J, Wang F, Colyer M, Lei H.

Exp Eye Res. 2020 Jan;190:107884. doi: 10.1016/j.exer.2019.107884. Epub 2019 Nov 29.


Blockade of MDM2 with inactive Cas9 prevents epithelial to mesenchymal transition in retinal pigment epithelial cells.

Liu B, Song J, Han H, Hu Z, Chen N, Cui J, Matsubara JA, Zhong J, Lei H.

Lab Invest. 2019 Dec;99(12):1874-1886. doi: 10.1038/s41374-019-0307-9. Epub 2019 Aug 22.


The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis.

Gao J, Cui JZ, Wang A, Chen HHR, Fong A, Matsubara JA.

J Neuroinflammation. 2019 Aug 22;16(1):171. doi: 10.1186/s12974-019-1558-5.


Association Between Preanalytical Factors and Tumor Mutational Burden Estimated by Next-Generation Sequencing-Based Multiplex Gene Panel Assay.

Quy PN, Kanai M, Fukuyama K, Kou T, Kondo T, Yamamoto Y, Matsubara J, Hiroshima A, Mochizuki H, Sakuma T, Kamada M, Nakatsui M, Eso Y, Seno H, Masui T, Takaori K, Minamiguchi S, Matsumoto S, Muto M.

Oncologist. 2019 Dec;24(12):e1401-e1408. doi: 10.1634/theoncologist.2018-0587. Epub 2019 Jun 11.


Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.

Hirohashi K, Ohashi S, Amanuma Y, Nakai Y, Ida T, Baba K, Mitani Y, Mizumoto A, Yamamoto Y, Kikuchi O, Matsubara J, Yamada A, Miyamoto S, Seno H, Matsuda T, Muto M.

Carcinogenesis. 2019 May 10. pii: bgz091. doi: 10.1093/carcin/bgz091. [Epub ahead of print]


Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma.

Mizumoto A, Ohashi S, Kamada M, Saito T, Nakai Y, Baba K, Hirohashi K, Mitani Y, Kikuchi O, Matsubara J, Yamada A, Takahashi T, Lee H, Okuno Y, Kanai M, Muto M.

J Gastroenterol. 2019 Aug;54(8):687-698. doi: 10.1007/s00535-019-01549-x. Epub 2019 Feb 8.


Lipopolysaccharide Induced Opening of the Blood Brain Barrier on Aging 5XFAD Mouse Model.

Barton SM, Janve VA, McClure R, Anderson A, Matsubara JA, Gore JC, Pham W.

J Alzheimers Dis. 2019;67(2):503-513. doi: 10.3233/JAD-180755.


Polarization imaging using an anisotropic diffraction grating and liquid crystal retarders.

Noda K, Momosaki R, Matsubara J, Sakamoto M, Sasaki T, Kawatsuki N, Goto K, Ono H.

Appl Opt. 2018 Oct 20;57(30):8870-8875. doi: 10.1364/AO.57.008870.


Drusen in the Peripheral Retina of the Alzheimer's Eye.

Ukalovic K, Cao S, Lee S, Tang Q, Beg MF, Sarunic MV, Hsiung GR, Mackenzie IR, Hirsch-Reinshagen V, Cui JZ, Matsubara JA.

Curr Alzheimer Res. 2018;15(8):743-750. doi: 10.2174/1567205015666180123122637.


Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye.

Gao J, Cui JZ, To E, Cao S, Matsubara JA.

J Neuroinflammation. 2018 Jan 12;15(1):15. doi: 10.1186/s12974-018-1062-3.


Understanding AMD by analogy: systematic review of lipid-related common pathogenic mechanisms in AMD, AD, AS and GN.

Xu Q, Cao S, Rajapakse S, Matsubara JA.

Lipids Health Dis. 2018 Jan 4;17(1):3. doi: 10.1186/s12944-017-0647-7. Review.


Analysis of reasons for noncompliance with laser treatment in patients of diabetic retinopathy.

Hua W, Cao S, Cui J, Maberley D, Matsubara J.

Can J Ophthalmol. 2017 Nov;52 Suppl 1:S34-S38. doi: 10.1016/j.jcjo.2017.09.025.


Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy.

Zhou G, Duan Y, Ma G, Wu W, Hu Z, Chen N, Chee Y, Cui J, Samad A, Matsubara JA, Mukai S, D'Amore PA, Lei H.

Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5361-5367. doi: 10.1167/iovs.17-22045.


Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis.

Gibbs E, Matsubara J, Cao S, Cui J, Forooghian F.

Can J Ophthalmol. 2017 Oct;52(5):463-467. doi: 10.1016/j.jcjo.2017.03.010. Epub 2017 May 10.


Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.

Yoshioka M, Ohashi S, Ida T, Nakai Y, Kikuchi O, Amanuma Y, Matsubara J, Yamada A, Miyamoto S, Natsuizaka M, Nakagawa H, Chiba T, Seno H, Muto M.

J Exp Clin Cancer Res. 2017 Aug 1;36(1):101. doi: 10.1186/s13046-017-0572-7.


Long-term in vitro functional stability of compounded ranibizumab and aflibercept.

Cao S, Cui J, Matsubara J, Forooghian F.

Can J Ophthalmol. 2017 Jun;52(3):273-276. doi: 10.1016/j.jcjo.2016.11.012. Epub 2017 Jan 11.


Colchicine Improves Survival, Left Ventricular Remodeling, and Chronic Cardiac Function After Acute Myocardial Infarction.

Fujisue K, Sugamura K, Kurokawa H, Matsubara J, Ishii M, Izumiya Y, Kaikita K, Sugiyama S.

Circ J. 2017 Jul 25;81(8):1174-1182. doi: 10.1253/circj.CJ-16-0949. Epub 2017 Apr 18.


Pre-procedural peripheral endothelial function is associated with increased serum creatinine following percutaneous coronary procedure in stable patients with a preserved estimated glomerular filtration rate.

Sumida H, Matsuzawa Y, Sugiyama S, Sugamura K, Nozaki T, Akiyama E, Ohba K, Konishi M, Matsubara J, Fujisue K, Maeda H, Kurokawa H, Iwashita S, Ogawa H, Tsujita K.

J Cardiol. 2017 Nov;70(5):461-469. doi: 10.1016/j.jjcc.2017.03.004. Epub 2017 Apr 11.


Structural divergence of essential triad ribbon synapse proteins among placental mammals - Implications for preclinical trials in photoreceptor transplantation therapy.

Laver CRJ, Matsubara JA.

Exp Eye Res. 2017 Jun;159:156-167. doi: 10.1016/j.exer.2017.03.005. Epub 2017 Mar 18.



Mammo Z, Guo M, Maberley D, Matsubara J, Etminan M.

Am J Ophthalmol. 2017 Apr;176:255-256. doi: 10.1016/j.ajo.2017.01.009. Epub 2017 Feb 9. No abstract available.


Pulmonary artery hypertension in methylmalonic acidemia.

Kido J, Mitsubuchi H, Sakanashi M, Matsubara J, Matsumoto S, Sakamoto R, Endo F, Nakamura K.

Hemodial Int. 2017 Apr;21(2):E25-E29. doi: 10.1111/hdi.12506. Epub 2016 Nov 1.


Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases.

Ma G, Duan Y, Huang X, Qian CX, Chee Y, Mukai S, Cui J, Samad A, Matsubara JA, Kazlauskas A, D'Amore PA, Gu S, Lei H.

Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3935-43. doi: 10.1167/iovs.16-19405. Erratum in: Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4213.



Pang CE, Maberley DA, Freund KB, White VA, Rasmussen S, To E, Matsubara JA.

Retina. 2016 Jul;36(7):1408-12. doi: 10.1097/IAE.0000000000001069.


Oral Bisphosphonates and Risk of Wet Age-Related Macular Degeneration.

Mammo Z, Guo M, Maberley D, Matsubara J, Etminan M.

Am J Ophthalmol. 2016 Aug;168:62-67. doi: 10.1016/j.ajo.2016.04.022. Epub 2016 May 7.


Alterations in intraocular cytokine levels following intravitreal ranibizumab.

Forooghian F, Kertes PJ, Eng KT, Albiani DA, Kirker AW, Merkur AB, Fallah N, Cao S, Cui J, Or C, Matsubara JA.

Can J Ophthalmol. 2016 Apr;51(2):87-90. doi: 10.1016/j.jcjo.2015.11.001.


CFH Y402H polymorphism and the complement activation product C5a: effects on NF-κB activation and inflammasome gene regulation.

Cao S, Wang JC, Gao J, Wong M, To E, White VA, Cui JZ, Matsubara JA.

Br J Ophthalmol. 2016 May;100(5):713-8. doi: 10.1136/bjophthalmol-2015-307213. Epub 2016 Jan 8.


Low-Normal Serum Sodium and Heart Failure-Related Events in Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction.

Kusaka H, Sugiyama S, Yamamoto E, Akiyama E, Matsuzawa Y, Hirata Y, Fujisue K, Kurokawa H, Matsubara J, Sugamura K, Maeda H, Jinnouchi H, Matsui K, Ogawa H.

Circ J. 2016;80(2):411-7. doi: 10.1253/circj.CJ-15-0878. Epub 2015 Dec 3.


Prognostic Significance of Peripheral Microvascular Endothelial Dysfunction in Heart Failure With Reduced Left Ventricular Ejection Fraction.

Fujisue K, Sugiyama S, Matsuzawa Y, Akiyama E, Sugamura K, Matsubara J, Kurokawa H, Maeda H, Hirata Y, Kusaka H, Yamamoto E, Iwashita S, Sumida H, Sakamoto K, Tsujita K, Kaikita K, Hokimoto S, Matsui K, Ogawa H.

Circ J. 2015;79(12):2623-31. doi: 10.1253/circj.CJ-15-0671. Epub 2015 Oct 21.


Advanced peripheral microvascular endothelial dysfunction and polyvascular disease in patients with high cardiovascular risk.

Maeda H, Sugiyama S, Jinnouchi H, Matsuzawa Y, Fujisue K, Hirata Y, Kurokawa H, Ohba K, Matsubara J, Nozaki T, Konishi M, Akiyama E, Sugamura K, Yamamoto E, Sumida H, Ogawa H.

J Cardiol. 2016 May;67(5):455-62. doi: 10.1016/j.jjcc.2015.07.003. Epub 2015 Sep 4.


General and Specific Strategies Used to Facilitate Locomotor Maneuvers.

Wu M, Matsubara JH, Gordon KE.

PLoS One. 2015 Jul 13;10(7):e0132707. doi: 10.1371/journal.pone.0132707. eCollection 2015.


Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye.

Zhao T, Gao J, Van J, To E, Wang A, Cao S, Cui JZ, Guo JP, Lee M, McGeer PL, Matsubara JA.

J Neuroinflammation. 2015 Jun 24;12:121. doi: 10.1186/s12974-015-0337-1.


T-SPOT.TB Interferon-γ Release Assay Performance in Healthcare Worker Screening at Nineteen U.S. Hospitals.

King TC, Upfal M, Gottlieb A, Adamo P, Bernacki E, Kadlecek CP, Jones JG, Humphrey-Carothers F, Rielly AF, Drewry P, Murray K, DeWitt M, Matsubara J, O'Dea L, Balser J, Wrighton-Smith P.

Am J Respir Crit Care Med. 2015 Aug 1;192(3):367-73. doi: 10.1164/rccm.201501-0199OC.


CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye.

Wang JC, Cao S, Wang A, To E, Law G, Gao J, Zhang D, Cui JZ, Matsubara JA.

Mol Vis. 2015 Mar 13;21:264-72. eCollection 2015.


The enigma of autoimmune retinopathy.

Forooghian F, Cao S, Cui J, Matsubara JA.

Int Ophthalmol Clin. 2015 Spring;55(2):81-91. doi: 10.1097/IIO.0000000000000063. Review. No abstract available.


NLRP3 inflammasome: activation and regulation in age-related macular degeneration.

Gao J, Liu RT, Cao S, Cui JZ, Wang A, To E, Matsubara JA.

Mediators Inflamm. 2015;2015:690243. doi: 10.1155/2015/690243. Epub 2015 Jan 27. Review.


Telmisartan enhances mitochondrial activity and alters cellular functions in human coronary artery endothelial cells via AMP-activated protein kinase pathway.

Kurokawa H, Sugiyama S, Nozaki T, Sugamura K, Toyama K, Matsubara J, Fujisue K, Ohba K, Maeda H, Konishi M, Akiyama E, Sumida H, Izumiya Y, Yasuda O, Kim-Mitsuyama S, Ogawa H.

Atherosclerosis. 2015 Apr;239(2):375-85. doi: 10.1016/j.atherosclerosis.2015.01.037. Epub 2015 Jan 31.


Decreased plasma levels of active glucagon-like peptide-1 in coronary artery disease.

Akiyama E, Sugiyama S, Matsubara J, Kurokawa H, Konishi M, Nozaki T, Ohba K, Fujisue K, Maeda H, Sakamoto K, Sugamura K, Sumida H, Jinnouchi H, Sakamaki K, Morita S, Kimura K, Umemura S, Ogawa H.

J Am Coll Cardiol. 2015 Feb 24;65(7):754-5. doi: 10.1016/j.jacc.2014.11.043. No abstract available.


Metabolic cost of lateral stabilization during walking in people with incomplete spinal cord injury.

Matsubara JH, Wu M, Gordon KE.

Gait Posture. 2015 Feb;41(2):646-51. doi: 10.1016/j.gaitpost.2015.01.015. Epub 2015 Jan 24.


Vinpocetine inhibits amyloid-beta induced activation of NF-κB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells.

Liu RT, Wang A, To E, Gao J, Cao S, Cui JZ, Matsubara JA.

Exp Eye Res. 2014 Oct;127:49-58. doi: 10.1016/j.exer.2014.07.003. Epub 2014 Jul 17.


Incremental prognostic significance of the elevated levels of pentraxin 3 in patients with heart failure with normal left ventricular ejection fraction.

Matsubara J, Sugiyama S, Nozaki T, Akiyama E, Matsuzawa Y, Kurokawa H, Maeda H, Fujisue K, Sugamura K, Yamamoto E, Matsui K, Jinnouchi H, Ogawa H.

J Am Heart Assoc. 2014 Jul 10;3(4). pii: e000928. doi: 10.1161/JAHA.114.000928.


Endothelial function and cardiovascular events in chronic kidney disease.

Hirata Y, Sugiyama S, Yamamoto E, Matsuzawa Y, Akiyama E, Kusaka H, Fujisue K, Kurokawa H, Matsubara J, Sugamura K, Maeda H, Iwashita S, Jinnouchi H, Matsui K, Ogawa H.

Int J Cardiol. 2014 May 15;173(3):481-6. doi: 10.1016/j.ijcard.2014.03.085. Epub 2014 Mar 20.


Peripheral endothelial function and cardiovascular events in high-risk patients.

Matsuzawa Y, Sugiyama S, Sumida H, Sugamura K, Nozaki T, Ohba K, Matsubara J, Kurokawa H, Fujisue K, Konishi M, Akiyama E, Suzuki H, Nagayoshi Y, Yamamuro M, Sakamoto K, Iwashita S, Jinnouchi H, Taguri M, Morita S, Matsui K, Kimura K, Umemura S, Ogawa H.

J Am Heart Assoc. 2013 Nov 25;2(6):e000426. doi: 10.1161/JAHA.113.000426.


Response to letter regarding article, "Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease".

Fujisue K, Sugiyama S, Ono T, Matsuzawa Y, Akiyama E, Sugamura K, Matsubara J, Kurokawa H, Kaikita K, Iwashita S, Sumida H, Hokimoto S, Oniki K, Nakagawa K, Matsui K, Ogawa H.

Circ Cardiovasc Interv. 2013 Oct 1;6(5):e66. doi: 10.1161/CIRCINTERVENTIONS.113.000788. No abstract available.


Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration.

Cao S, Ko A, Partanen M, Pakzad-Vaezi K, Merkur AB, Albiani DA, Kirker AW, Wang A, Cui JZ, Forooghian F, Matsubara JA.

Am J Ophthalmol. 2013 Dec;156(6):1176-83. doi: 10.1016/j.ajo.2013.08.003. Epub 2013 Sep 29.


Effects of endothelial dysfunction on residual platelet aggregability after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease.

Fujisue K, Sugiyama S, Ono T, Matsuzawa Y, Akiyama E, Sugamura K, Matsubara J, Kurokawa H, Kaikita K, Iwashita S, Sumida H, Hokimoto S, Oniki K, Nakagawa K, Matsui K, Ogawa H.

Circ Cardiovasc Interv. 2013 Aug;6(4):452-9. doi: 10.1161/CIRCINTERVENTIONS.112.000278. Epub 2013 Aug 6.


Pro-inflammatory and anti-angiogenic effects of bisphosphonates on human cultured retinal pigment epithelial cells.

Or C, Cui J, Matsubara J, Forooghian F.

Br J Ophthalmol. 2013 Aug;97(8):1074-8. doi: 10.1136/bjophthalmol-2013-303355. Epub 2013 Jun 13.


Parainflammation associated with advanced glycation endproduct stimulation of RPE in vitro: implications for age-related degenerative diseases of the eye.

Lin T, Walker GB, Kurji K, Fang E, Law G, Prasad SS, Kojic L, Cao S, White V, Cui JZ, Matsubara JA.

Cytokine. 2013 Jun;62(3):369-81. doi: 10.1016/j.cyto.2013.03.027. Epub 2013 Apr 17.


Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease.

Pennock S, Kim D, Mukai S, Kuhnle M, Chun DW, Matsubara J, Cui J, Ma P, Maberley D, Samad A, Van Geest RJ, Oberstein SL, Schlingemann RO, Kazlauskas A.

Am J Pathol. 2013 May;182(5):1659-70. doi: 10.1016/j.ajpath.2013.01.052. Epub 2013 Apr 9.


Basal and ischemia-induced transcardiac troponin release into the coronary circulation in patients with suspected coronary artery disease.

Konishi M, Sugiyama S, Sugamura K, Nozaki T, Ohba K, Matsubara J, Sakamoto K, Nagayoshi Y, Sumida H, Akiyama E, Matsuzawa Y, Sakamaki K, Morita S, Kimura K, Umemura S, Ogawa H.

PLoS One. 2013;8(4):e60163. doi: 10.1371/journal.pone.0060163. Epub 2013 Apr 2.

Supplemental Content

Loading ...
Support Center