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Immobilization of β-Galactosidases on the Lactobacillus Cell Surface Using the Peptidoglycan-Binding Motif LysM.

Pham ML, Tran AM, Kittibunchakul S, Nguyen TT, Mathiesen G, Nguyen TH.

Catalysts. 2019 May;9(5):443. doi: 10.3390/catal9050443.


Comparison of eight Lactobacillus species for delivery of surface-displayed mycobacterial antigen.

Kuczkowska K, Øverland L, Rocha SDC, Eijsink VGH, Mathiesen G.

Vaccine. 2019 Oct 8;37(43):6371-6379. doi: 10.1016/j.vaccine.2019.09.012. Epub 2019 Sep 13.


Comparison of three seemingly similar lytic polysaccharide monooxygenases from Neurospora crassa suggests different roles in plant biomass degradation.

Petrović DM, Várnai A, Dimarogona M, Mathiesen G, Sandgren M, Westereng B, Eijsink VGH.

J Biol Chem. 2019 Oct 11;294(41):15068-15081. doi: 10.1074/jbc.RA119.008196. Epub 2019 Aug 20.


Inactivated Lactobacillus plantarum Carrying a Surface-Displayed Ag85B-ESAT-6 Fusion Antigen as a Booster Vaccine Against Mycobacterium tuberculosis Infection.

Kuczkowska K, Copland A, Øverland L, Mathiesen G, Tran AC, Paul MJ, Eijsink VGH, Reljic R.

Front Immunol. 2019 Jul 9;10:1588. doi: 10.3389/fimmu.2019.01588. eCollection 2019.


Constitutive expression and cell-surface display of a bacterial β-mannanase in Lactobacillus plantarum.

Nguyen HM, Pham ML, Stelzer EM, Plattner E, Grabherr R, Mathiesen G, Peterbauer CK, Haltrich D, Nguyen TH.

Microb Cell Fact. 2019 Apr 25;18(1):76. doi: 10.1186/s12934-019-1124-y.


CRISPR Interference for Rapid Knockdown of Essential Cell Cycle Genes in Lactobacillus plantarum.

Myrbråten IS, Wiull K, Salehian Z, Håvarstein LS, Straume D, Mathiesen G, Kjos M.

mSphere. 2019 Mar 20;4(2). pii: e00007-19. doi: 10.1128/mSphere.00007-19.


Over 2000-Fold Increased Production of the Leaderless Bacteriocin Garvicin KS by Increasing Gene Dose and Optimization of Culture Conditions.

Telke AA, Ovchinnikov KV, Vuoristo KS, Mathiesen G, Thorstensen T, Diep DB.

Front Microbiol. 2019 Mar 5;10:389. doi: 10.3389/fmicb.2019.00389. eCollection 2019.


Profiling of microorganism-binding serum antibody specificities in professional athletes.

Minić R, Papić Z, Đorđević B, Michaličkova D, Ilić V, Mathiesen G, Živković I, Pantic V, Dimitrijević L.

PLoS One. 2018 Sep 25;13(9):e0203665. doi: 10.1371/journal.pone.0203665. eCollection 2018.


Structure and function of a broad-specificity chitin deacetylase from Aspergillus nidulans FGSC A4.

Liu Z, Gay LM, Tuveng TR, Agger JW, Westereng B, Mathiesen G, Horn SJ, Vaaje-Kolstad G, van Aalten DMF, Eijsink VGH.

Sci Rep. 2017 May 11;7(1):1746. doi: 10.1038/s41598-017-02043-1.


Lactobacillus plantarum producing a Chlamydia trachomatis antigen induces a specific IgA response after mucosal booster immunization.

Kuczkowska K, Myrbråten I, Øverland L, Eijsink VGH, Follmann F, Mathiesen G, Dietrich J.

PLoS One. 2017 May 3;12(5):e0176401. doi: 10.1371/journal.pone.0176401. eCollection 2017.


From by-product to valuable components: Efficient enzymatic conversion of lactose in whey using β-galactosidase from Streptococcus thermophilus.

Geiger B, Nguyen HM, Wenig S, Nguyen HA, Lorenz C, Kittl R, Mathiesen G, Eijsink VG, Haltrich D, Nguyen TH.

Biochem Eng J. 2016 Dec 15;116:45-53.


Immunogenic Properties of Lactobacillus plantarum Producing Surface-Displayed Mycobacterium tuberculosis Antigens.

Kuczkowska K, Kleiveland CR, Minic R, Moen LF, Øverland L, Tjåland R, Carlsen H, Lea T, Mathiesen G, Eijsink VGH.

Appl Environ Microbiol. 2016 Dec 30;83(2). pii: e02782-16. doi: 10.1128/AEM.02782-16. Print 2017 Jan 15.


Display of a β-mannanase and a chitosanase on the cell surface of Lactobacillus plantarum towards the development of whole-cell biocatalysts.

Nguyen HM, Mathiesen G, Stelzer EM, Pham ML, Kuczkowska K, Mackenzie A, Agger JW, Eijsink VG, Yamabhai M, Peterbauer CK, Haltrich D, Nguyen TH.

Microb Cell Fact. 2016 Oct 4;15(1):169.


Secretory production of a beta-mannanase and a chitosanase using a Lactobacillus plantarum expression system.

Sak-Ubol S, Namvijitr P, Pechsrichuang P, Haltrich D, Nguyen TH, Mathiesen G, Eijsink VG, Yamabhai M.

Microb Cell Fact. 2016 May 12;15:81. doi: 10.1186/s12934-016-0481-z.


Display of recombinant proteins at the surface of lactic acid bacteria: strategies and applications.

Michon C, Langella P, Eijsink VG, Mathiesen G, Chatel JM.

Microb Cell Fact. 2016 May 3;15:70. doi: 10.1186/s12934-016-0468-9. Review.


Erratum to: Surface display of an anti-DEC-205 single chain Fv fragment in Lactobacillus plantarum increases internalization and plasmid transfer to dendritic cells in vitro and in vivo.

Michon C, Kuczkowska K, Langella P, Eijsink VG, Mathiesen G, Chatel JM.

Microb Cell Fact. 2015 Nov 17;14(1):184. doi: 10.1186/s12934-015-0366-6. No abstract available.


Lactobacillus plantarum displaying CCL3 chemokine in fusion with HIV-1 Gag derived antigen causes increased recruitment of T cells.

Kuczkowska K, Mathiesen G, Eijsink VG, Øynebråten I.

Microb Cell Fact. 2015 Oct 22;14:169. doi: 10.1186/s12934-015-0360-z.


A novel proteomics sample preparation method for secretome analysis of Hypocrea jecorina growing on insoluble substrates.

Bengtsson O, Arntzen MØ, Mathiesen G, Skaugen M, Eijsink VGH.

J Proteomics. 2016 Jan 10;131:104-112. doi: 10.1016/j.jprot.2015.10.017. Epub 2015 Oct 23.


Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells.

Mobergslien A, Vasovic V, Mathiesen G, Fredriksen L, Westby P, Eijsink VG, Peng Q, Sioud M.

Hum Vaccin Immunother. 2015;11(11):2664-73. doi: 10.1080/21645515.2015.1056952. Epub 2015 Jul 17.


Structural and Functional Characterization of a Lytic Polysaccharide Monooxygenase with Broad Substrate Specificity.

Borisova AS, Isaksen T, Dimarogona M, Kognole AA, Mathiesen G, Várnai A, Røhr ÅK, Payne CM, Sørlie M, Sandgren M, Eijsink VG.

J Biol Chem. 2015 Sep 18;290(38):22955-69. doi: 10.1074/jbc.M115.660183. Epub 2015 Jul 15.


Thermodynamic Relationships with Processivity in Serratia marcescens Family 18 Chitinases.

Hamre AG, Jana S, Holen MM, Mathiesen G, Väljamäe P, Payne CM, Sørlie M.

J Phys Chem B. 2015 Jul 30;119(30):9601-13. doi: 10.1021/acs.jpcb.5b03817. Epub 2015 Jul 22.


Proteomic Investigation of the Response of Enterococcus faecalis V583 when Cultivated in Urine.

Arntzen MØ, Karlskås IL, Skaugen M, Eijsink VG, Mathiesen G.

PLoS One. 2015 Apr 27;10(4):e0126694. doi: 10.1371/journal.pone.0126694. eCollection 2015.


Heterologous expression of a recombinant lactobacillal β-galactosidase in Lactobacillus plantarum: effect of different parameters on the sakacin P-based expression system.

Nguyen TT, Nguyen HM, Geiger B, Mathiesen G, Eijsink VG, Peterbauer CK, Haltrich D, Nguyen TH.

Microb Cell Fact. 2015 Mar 7;14:30. doi: 10.1186/s12934-015-0214-8.


Effects of orally applied Fes p1-displaying L. plantarum WCFS1 on Fes p1 induced allergy in mice.

Minic R, Gavrovic-Jankulovic M, Petrusic V, Zivkovic I, Eijsink VG, Dimitrijevic L, Mathiesen G.

J Biotechnol. 2015 Apr 10;199:23-8. doi: 10.1016/j.jbiotec.2015.01.028. Epub 2015 Feb 14.


EF0176 and EF0177 from Enterococcus faecalis V583 are substrate-binding lipoproteins involved in ABC transporter mediated ribonucleoside uptake.

Karlskås IL, Saleihan Z, Holo H, Mathiesen G, Eijsink VG.

Microbiology. 2015 Apr;161(Pt 4):754-64. doi: 10.1099/mic.0.000045. Epub 2015 Jan 29.


The paratransgenic potential of Lactobacillus kunkeei in the honey bee Apis mellifera.

Rangberg A, Mathiesen G, Amdam GV, Diep DB.

Benef Microbes. 2015;6(4):513-23. doi: 10.3920/BM2014.0115. Epub 2015 Feb 12.


Computational and experimental analysis of the secretome of Methylococcus capsulatus (Bath).

Indrelid S, Mathiesen G, Jacobsen M, Lea T, Kleiveland CR.

PLoS One. 2014 Dec 5;9(12):e114476. doi: 10.1371/journal.pone.0114476. eCollection 2014.


Expression of endoglucanases in Pichia pastoris under control of the GAP promoter.

Várnai A, Tang C, Bengtsson O, Atterton A, Mathiesen G, Eijsink VG.

Microb Cell Fact. 2014 Apr 18;13(1):57. doi: 10.1186/1475-2859-13-57.


Heterologous protein secretion in Lactobacilli with modified pSIP vectors.

Karlskås IL, Maudal K, Axelsson L, Rud I, Eijsink VG, Mathiesen G.

PLoS One. 2014 Mar 10;9(3):e91125. doi: 10.1371/journal.pone.0091125. eCollection 2014.


Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration.

Dimitrijevic R, Ivanovic N, Mathiesen G, Petrusic V, Zivkovic I, Djordjevic B, Dimitrijevic L.

J Dairy Res. 2014 May;81(2):202-7. doi: 10.1017/S0022029914000028. Epub 2014 Feb 24.


Lactobacillus plantarum WCFS1 O-linked protein glycosylation: an extended spectrum of target proteins and modification sites detected by mass spectrometry.

Fredriksen L, Moen A, Adzhubei AA, Mathiesen G, Eijsink VG, Egge-Jacobsen W.

Glycobiology. 2013 Dec;23(12):1439-51. doi: 10.1093/glycob/cwt071. Epub 2013 Sep 1.


Experimental and computational analysis of the secretome of the hyperthermophilic archaeon Pyrococcus furiosus.

Schmid G, Mathiesen G, Arntzen MO, Eijsink VG, Thomm M.

Extremophiles. 2013 Nov;17(6):921-30. doi: 10.1007/s00792-013-0574-0. Epub 2013 Aug 27.


Establishment of a simple Lactobacillus plantarum cell consortium for cellulase-xylanase synergistic interactions.

Moraïs S, Shterzer N, Grinberg IR, Mathiesen G, Eijsink VG, Axelsson L, Lamed R, Bayer EA, Mizrahi I.

Appl Environ Microbiol. 2013 Sep;79(17):5242-9. doi: 10.1128/AEM.01211-13. Epub 2013 Jun 28.


Surface display of N-terminally anchored invasin by Lactobacillus plantarum activates NF-κB in monocytes.

Fredriksen L, Kleiveland CR, Hult LT, Lea T, Nygaard CS, Eijsink VG, Mathiesen G.

Appl Environ Microbiol. 2012 Aug;78(16):5864-71. doi: 10.1128/AEM.01227-12. Epub 2012 Jun 15.


Heterologous expression of Oenococcus oeni malolactic enzyme in Lactobacillus plantarum for improved malolactic fermentation.

Schümann C, Michlmayr H, Eder R, Del Hierro AM, Kulbe KD, Mathiesen G, Nguyen TH.

AMB Express. 2012 Mar 27;2(1):19. doi: 10.1186/2191-0855-2-19.


Homodimeric β-galactosidase from Lactobacillus delbrueckii subsp. bulgaricus DSM 20081: expression in Lactobacillus plantarum and biochemical characterization.

Nguyen TT, Nguyen HA, Arreola SL, Mlynek G, Djinović-Carugo K, Mathiesen G, Nguyen TH, Haltrich D.

J Agric Food Chem. 2012 Feb 22;60(7):1713-21. doi: 10.1021/jf203909e. Epub 2012 Feb 9.


Characterization of the chitinolytic machinery of Enterococcus faecalis V583 and high-resolution structure of its oxidative CBM33 enzyme.

Vaaje-Kolstad G, Bøhle LA, Gåseidnes S, Dalhus B, Bjørås M, Mathiesen G, Eijsink VG.

J Mol Biol. 2012 Feb 17;416(2):239-54. doi: 10.1016/j.jmb.2011.12.033. Epub 2011 Dec 22.


An endo-β-N-acetylglucosaminidase from Enterococcus faecalis V583 responsible for the hydrolysis of high-mannose and hybrid-type N-linked glycans.

Bøhle LA, Mathiesen G, Vaaje-Kolstad G, Eijsink VG.

FEMS Microbiol Lett. 2011 Dec;325(2):123-9. doi: 10.1111/j.1574-6968.2011.02419.x. Epub 2011 Oct 4.


The major autolysin Acm2 from Lactobacillus plantarum undergoes cytoplasmic O-glycosylation.

Fredriksen L, Mathiesen G, Moen A, Bron PA, Kleerebezem M, Eijsink VG, Egge-Jacobsen W.

J Bacteriol. 2012 Jan;194(2):325-33. doi: 10.1128/JB.06314-11. Epub 2011 Nov 11.


Chitinase from Bacillus licheniformis DSM13: expression in Lactobacillus plantarum WCFS1 and biochemical characterisation.

Nguyen HA, Nguyen TH, Nguyen TT, Peterbauer CK, Mathiesen G, Haltrich D.

Protein Expr Purif. 2012 Feb;81(2):166-74. doi: 10.1016/j.pep.2011.10.005. Epub 2011 Oct 19.


Quantitative transcript analysis of the inducible expression system pSIP: comparison of the overexpression of Lactobacillus spp. β-galactosidases in Lactobacillus plantarum.

Nguyen TT, Nguyen TH, Maischberger T, Schmelzer P, Mathiesen G, Eijsink VG, Haltrich D, Peterbauer CK.

Microb Cell Fact. 2011 Jun 22;10:46. doi: 10.1186/1475-2859-10-46.


A food-grade system for inducible gene expression in Lactobacillus plantarum using an alanine racemase-encoding selection marker.

Nguyen TT, Mathiesen G, Fredriksen L, Kittl R, Nguyen TH, Eijsink VG, Haltrich D, Peterbauer CK.

J Agric Food Chem. 2011 May 25;59(10):5617-24. doi: 10.1021/jf104755r. Epub 2011 Apr 29.


Identification of surface proteins in Enterococcus faecalis V583.

Bøhle LA, Riaz T, Egge-Jacobsen W, Skaugen M, Busk ØL, Eijsink VG, Mathiesen G.

BMC Genomics. 2011 Mar 1;12:135. doi: 10.1186/1471-2164-12-135.


Transcriptome, proteome, and metabolite analyses of a lactate dehydrogenase-negative mutant of Enterococcus faecalis V583.

Mehmeti I, Jönsson M, Fergestad EM, Mathiesen G, Nes IF, Holo H.

Appl Environ Microbiol. 2011 Apr;77(7):2406-13. doi: 10.1128/AEM.02485-10. Epub 2011 Feb 4.


Cell wall anchoring of the 37-kilodalton oncofetal antigen by Lactobacillus plantarum for mucosal cancer vaccine delivery.

Fredriksen L, Mathiesen G, Sioud M, Eijsink VG.

Appl Environ Microbiol. 2010 Nov;76(21):7359-62. doi: 10.1128/AEM.01031-10. Epub 2010 Sep 17.


Identification of proteins related to the stress response in Enterococcus faecalis V583 caused by bovine bile.

Bøhle LA, Færgestad EM, Veiseth-Kent E, Steinmoen H, Nes IF, Eijsink VG, Mathiesen G.

Proteome Sci. 2010 Jun 25;8:37. doi: 10.1186/1477-5956-8-37.


Genome-wide analysis of signal peptide functionality in Lactobacillus plantarum WCFS1.

Mathiesen G, Sveen A, Brurberg MB, Fredriksen L, Axelsson L, Eijsink VG.

BMC Genomics. 2009 Sep 10;10:425. doi: 10.1186/1471-2164-10-425.


Use of lactobacilli and their pheromone-based regulatory mechanism in gene expression and drug delivery.

Diep DB, Mathiesen G, Eijsink VG, Nes IF.

Curr Pharm Biotechnol. 2009 Jan;10(1):62-73. Review.


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