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Items: 1 to 50 of 64

1.

2B4 (CD244, SLAMF4) and CS1 (CD319, SLAMF7) in systemic lupus erythematosus and cancer.

Malaer JD, Marrufo AM, Mathew PA.

Clin Immunol. 2019 Jul;204:50-56. doi: 10.1016/j.clim.2018.10.009. Epub 2018 Oct 19. Review.

PMID:
30347240
2.

Blocking LLT1 (CLEC2D, OCIL)-NKRP1A (CD161) interaction enhances natural killer cell-mediated lysis of triple-negative breast cancer cells.

Marrufo AM, Mathew SO, Chaudhary P, Malaer JD, Vishwanatha JK, Mathew PA.

Am J Cancer Res. 2018 Jun 1;8(6):1050-1063. eCollection 2018.

3.

A novel ligand on astrocytes interacts with natural cytotoxicity receptor NKp44 regulating immune response mediated by NK cells.

Bowen KE, Mathew SO, Borgmann K, Ghorpade A, Mathew PA.

PLoS One. 2018 Feb 15;13(2):e0193008. doi: 10.1371/journal.pone.0193008. eCollection 2018.

4.

CS1 (SLAMF7, CD319) is an effective immunotherapeutic target for multiple myeloma.

Malaer JD, Mathew PA.

Am J Cancer Res. 2017 Aug 1;7(8):1637-1641. eCollection 2017. Review.

5.

Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction.

Mathew SO, Chaudhary P, Powers SB, Vishwanatha JK, Mathew PA.

Oncotarget. 2016 Oct 18;7(42):68650-68661. doi: 10.18632/oncotarget.11896.

6.

Blimp-1/PRDM1 regulates the transcription of human CS1 (SLAMF7) gene in NK and B cells.

Kim JR, Mathew SO, Mathew PA.

Immunobiology. 2016 Jan;221(1):31-9. doi: 10.1016/j.imbio.2015.08.005. Epub 2015 Aug 15.

PMID:
26310579
7.

NKp44 and Natural Cytotoxicity Receptors as Damage-Associated Molecular Pattern Recognition Receptors.

Horton NC, Mathew PA.

Front Immunol. 2015 Feb 2;6:31. doi: 10.3389/fimmu.2015.00031. eCollection 2015. Review.

8.

CS1 (SLAMF7) inhibits production of proinflammatory cytokines by activated monocytes.

Kim JR, Horton NC, Mathew SO, Mathew PA.

Inflamm Res. 2013 Aug;62(8):765-72. doi: 10.1007/s00011-013-0632-1. Epub 2013 May 22.

PMID:
23695528
9.

Novel interaction between proliferating cell nuclear antigen and HLA I on the surface of tumor cells inhibits NK cell function through NKp44.

Horton NC, Mathew SO, Mathew PA.

PLoS One. 2013;8(3):e59552. doi: 10.1371/journal.pone.0059552. Epub 2013 Mar 19.

10.

Stereoselective synthesis of complex polycyclic aziridines: use of the Brønsted acid-catalyzed aza-Darzens reaction to prepare an orthogonally protected mitomycin C intermediate with maximal convergency.

Srinivasan JM, Mathew PA, Williams AL, Huffman JC, Johnston JN.

Chem Commun (Camb). 2011 Apr 7;47(13):3975-7. doi: 10.1039/c0cc05734g. Epub 2011 Feb 24.

11.

2B4+ CD8+ T cells play an inhibitory role against constrained HIV epitopes.

Aldy KN, Horton NC, Mathew PA, Mathew SO.

Biochem Biophys Res Commun. 2011 Feb 18;405(3):503-7. doi: 10.1016/j.bbrc.2011.01.062. Epub 2011 Jan 21.

12.

Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis.

Waggoner SN, Taniguchi RT, Mathew PA, Kumar V, Welsh RM.

J Clin Invest. 2010 Jun;120(6):1925-38. doi: 10.1172/JCI41264. Epub 2010 May 3.

13.

LLT1-mediated activation of IFN-gamma production in human natural killer cells involves ERK signalling pathway.

Bambard ND, Mathew SO, Mathew PA.

Scand J Immunol. 2010 Mar;71(3):210-9. doi: 10.1111/j.1365-3083.2009.02367.x.

14.

Altered expression of signalling lymphocyte activation molecule (SLAM) family receptors CS1 (CD319) and 2B4 (CD244) in patients with systemic lupus erythematosus.

Kim JR, Mathew SO, Patel RK, Pertusi RM, Mathew PA.

Clin Exp Immunol. 2010 Jun;160(3):348-58. doi: 10.1111/j.1365-2249.2010.04116.x. Epub 2010 Mar 16.

15.

Functional role of human NK cell receptor 2B4 (CD244) isoforms.

Mathew SO, Rao KK, Kim JR, Bambard ND, Mathew PA.

Eur J Immunol. 2009 Jun;39(6):1632-41. doi: 10.1002/eji.200838733.

16.

CS1 (CRACC, CD319) induces proliferation and autocrine cytokine expression on human B lymphocytes.

Lee JK, Mathew SO, Vaidya SV, Kumaresan PR, Mathew PA.

J Immunol. 2007 Oct 1;179(7):4672-8.

17.

Human natural killer cell receptor 2B4 (CD244) down-regulates its own expression by reduced promoter activity at an Ets element.

Mathew SO, Vaidya SV, Kim JR, Mathew PA.

Biochem Biophys Res Commun. 2007 Apr 6;355(2):483-7. Epub 2007 Feb 7.

18.

Of mice and men: different functions of the murine and human 2B4 (CD244) receptor on NK cells.

Vaidya SV, Mathew PA.

Immunol Lett. 2006 Jun 15;105(2):180-4. Epub 2006 Mar 15. Review.

PMID:
16621032
19.

Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor.

Rosen DB, Bettadapura J, Alsharifi M, Mathew PA, Warren HS, Lanier LL.

J Immunol. 2005 Dec 15;175(12):7796-9.

21.

Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions.

Lee KM, Forman JP, McNerney ME, Stepp S, Kuppireddi S, Guzior D, Latchman YE, Sayegh MH, Yagita H, Park CK, Oh SB, Wülfing C, Schatzle J, Mathew PA, Sharpe AH, Kumar V.

Blood. 2006 Apr 15;107(8):3181-8. Epub 2005 May 19.

22.

An Ets element regulates the transcription of the human 2B4 gene in natural killer cells.

Vaidya SV, Mathew PA.

Biochim Biophys Acta. 2005 May 1;1728(3):181-5. Epub 2005 Feb 19.

PMID:
15777706
23.

Targeted disruption of the 2B4 gene in mice reveals an in vivo role of 2B4 (CD244) in the rejection of B16 melanoma cells.

Vaidya SV, Stepp SE, McNerney ME, Lee JK, Bennett M, Lee KM, Stewart CL, Kumar V, Mathew PA.

J Immunol. 2005 Jan 15;174(2):800-7.

25.

Papillary thyroid carcinoma and its variants in fine needle aspiration smears. A cytomorphologic study with special reference to tall cell variant.

Das DK, Mallik MK, Sharma P, Sheikh ZA, Mathew PA, Sheikh M, Mirza K, Madda JP, Francis IM, Junaid TA.

Acta Cytol. 2004 May-Jun;48(3):325-36.

PMID:
15192947
26.

2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells.

Lee KM, McNerney ME, Stepp SE, Mathew PA, Schatzle JD, Bennett M, Kumar V.

J Exp Med. 2004 May 3;199(9):1245-54.

27.

The LLT1 receptor induces IFN-gamma production by human natural killer cells.

Mathew PA, Chuang SS, Vaidya SV, Kumaresan PR, Boles KS, Pham HT.

Mol Immunol. 2004 Mar;40(16):1157-63.

PMID:
15104121
28.

2B4(CD244)-mediated activation of NK cells reduces metastases of B16F10 melanoma in mice.

Johnson LA, Vaidya SV, Goldfarb RH, Mathew PA.

Anticancer Res. 2003 Sep-Oct;23(5A):3651-5.

PMID:
14666660
29.
30.

CS1, a novel member of the CD2 family, is homophilic and regulates NK cell function.

Kumaresan PR, Lai WC, Chuang SS, Bennett M, Mathew PA.

Mol Immunol. 2002 Sep;39(1-2):1-8.

PMID:
12213321
31.
32.
33.

A prominent role for activator protein-1 in the transcription of the human 2B4 (CD244) gene in NK cells.

Chuang SS, Pham HT, Kumaresan PR, Mathew PA.

J Immunol. 2001 May 15;166(10):6188-95.

34.

Molecular characterization of the rat NK cell receptor 2B4.

Kumaresan PR, Stepp SE, Verrett PC, Chuang SS, Boles KS, Lai WC, Ryan JC, Bennett M, Kumar V, Mathew PA.

Mol Immunol. 2000 Aug-Sep;37(12-13):735-44.

PMID:
11275258
35.
36.

Regulation of IFN-gamma production following 2B4 activation in human NK cells.

Johnson LA, Goldfarb RH, Mathew PA.

In Vivo. 2000 Sep-Oct;14(5):625-9.

PMID:
11125547
37.

Structure of the human natural killer cell receptor 2B4 gene and identification of a novel alternative transcript.

Kumaresan PR, Mathew PA.

Immunogenetics. 2000 Sep;51(11):987-92. No abstract available.

PMID:
11003394
38.

Polymorphism in the 2B4 gene of inbred mouse strains.

Kumaresan PR, Huynh VT, Mathew PA.

Immunogenetics. 2000 Jul;51(8-9):758-61. No abstract available.

PMID:
10941850
39.

2B4 stimulation of YT cells induces natural killer cell cytolytic function and invasiveness.

Chuang SS, Kim MH, Johnson LA, Albertsson P, Kitson RP, Nannmark U, Goldfarb RH, Mathew PA.

Immunology. 2000 Jul;100(3):378-83.

40.

Perforin: more than just an effector molecule.

Stepp SE, Mathew PA, Bennett M, de Saint Basile G, Kumar V.

Immunol Today. 2000 Jun;21(6):254-6. Review. No abstract available.

PMID:
10825735
41.

Molecular cloning of transmembrane and soluble forms of a novel rat natural killer cell receptor related to 2B4.

Kumaresan PR, Stepp SE, Bennett M, Kumar V, Mathew PA.

Immunogenetics. 2000 Apr;51(4-5):306-13.

PMID:
10803843
42.

Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

Stepp SE, Dufourcq-Lagelouse R, Le Deist F, Bhawan S, Certain S, Mathew PA, Henter JI, Bennett M, Fischer A, de Saint Basile G, Kumar V.

Science. 1999 Dec 3;286(5446):1957-9.

43.

Molecular cloning and characterization of the promoter region of murine natural killer cell receptor 2B4.

Chuang SS, Lee Y, Stepp SE, Kumaresan PR, Mathew PA.

Biochim Biophys Acta. 1999 Oct 28;1447(2-3):244-50.

PMID:
10542322
44.

Cloning of a new lectin-like receptor expressed on human NK cells.

Boles KS, Barten R, Kumaresan PR, Trowsdale J, Mathew PA.

Immunogenetics. 1999 Oct;50(1-2):1-7.

PMID:
10541800
45.

Gene structure of the murine NK cell receptor 2B4: presence of two alternatively spliced isoforms with distinct cytoplasmic domains.

Stepp SE, Schatzle JD, Bennett M, Kumar V, Mathew PA.

Eur J Immunol. 1999 Aug;29(8):2392-9.

PMID:
10458751
46.

Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4.

Boles KS, Nakajima H, Colonna M, Chuang SS, Stepp SE, Bennett M, Kumar V, Mathew PA.

Tissue Antigens. 1999 Jul;54(1):27-34.

PMID:
10458320
47.

Characterization of inhibitory and stimulatory forms of the murine natural killer cell receptor 2B4.

Schatzle JD, Sheu S, Stepp SE, Mathew PA, Bennett M, Kumar V.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3870-5.

48.

2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48.

Brown MH, Boles K, van der Merwe PA, Kumar V, Mathew PA, Barclay AN.

J Exp Med. 1998 Dec 7;188(11):2083-90.

49.

Allorecognition by murine natural killer cells: lysis of T-lymphoblasts and rejection of bone-marrow grafts.

George T, Yu YY, Liu J, Davenport C, Lemieux S, Stoneman E, Mathew PA, Kumar V, Bennett M.

Immunol Rev. 1997 Feb;155:29-40. Review.

PMID:
9059880
50.

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