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Items: 1 to 50 of 70

1.

Transcriptomic analyses of oncogenic hepatocytes reveal common and different molecular pathways of hepatocarcinogenesis in different developmental stages and genders in krasG12V transgenic zebrafish.

Huo X, Li H, Li Z, Yan C, Mathavan S, Liu J, Gong Z.

Biochem Biophys Res Commun. 2019 Mar 19;510(4):558-564. doi: 10.1016/j.bbrc.2019.02.008. Epub 2019 Feb 7.

PMID:
30739784
2.

Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish.

Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z.

Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8.

3.

Morphological, Stability, and Hypoglycemic Effects of New Gliclazide-Bile Acid Microcapsules for Type 1 Diabetes Treatment: the Microencapsulation of Anti-diabetics Using a Microcapsule-Stabilizing Bile Acid.

Mathavan S, Chen-Tan N, Arfuso F, Al-Salami H.

AAPS PharmSciTech. 2018 Oct;19(7):3009-3018. doi: 10.1208/s12249-018-1127-8. Epub 2018 Jul 30.

PMID:
30062539
4.

IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis.

Chekuri A, Guru AA, Biswas P, Branham K, Borooah S, Soto-Hermida A, Hicks M, Khan NW, Matsui H, Alapati A, Raghavendra PB, Roosing S, Sarangapani S, Mathavan S, Telenti A, Heckenlively JR, Riazuddin SA, Frazer KA, Sieving PA, Ayyagari R.

Hum Genet. 2018 Jul;137(6-7):447-458. doi: 10.1007/s00439-018-1897-9. Epub 2018 Jul 5.

PMID:
29978320
5.

Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal-to-zygotic transition.

Winata CL, Łapiński M, Pryszcz L, Vaz C, Bin Ismail MH, Nama S, Hajan HS, Lee SGP, Korzh V, Sampath P, Tanavde V, Mathavan S.

Development. 2018 Jan 8;145(1). pii: dev159566. doi: 10.1242/dev.159566.

6.

Ikk2 regulates cytokinesis during vertebrate development.

Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V.

Sci Rep. 2017 Aug 14;7(1):8094. doi: 10.1038/s41598-017-06904-7.

7.

Diabetes development increased concentrations of the conjugated bile acid, taurocholic acid in serum, while treatment with microencapsulated-taurocholic acid exerted no hypoglycaemic effects.

Mathavan S, Mikov M, Golocorbin-Kon S, Al-Salami H.

Eur J Pharm Sci. 2017 Aug 30;106:1-9. doi: 10.1016/j.ejps.2017.05.041. Epub 2017 May 19.

PMID:
28529037
8.

Mammary Gland Pathology Subsequent to Acute Infection with Strong versus Weak Biofilm Forming Staphylococcus aureus Bovine Mastitis Isolates: A Pilot Study Using Non-Invasive Mouse Mastitis Model.

Gogoi-Tiwari J, Williams V, Waryah CB, Costantino P, Al-Salami H, Mathavan S, Wells K, Tiwari HK, Hegde N, Isloor S, Al-Sallami H, Mukkur T.

PLoS One. 2017 Jan 27;12(1):e0170668. doi: 10.1371/journal.pone.0170668. eCollection 2017.

9.

Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.

Poon KL, Wang X, Lee SG, Ng AS, Goh WH, Zhao Z, Al-Haddawi M, Wang H, Mathavan S, Ingham PW, McGinnis C, Carney TJ.

Toxicol Sci. 2017 Mar 1;156(1):133-148. doi: 10.1093/toxsci/kfw250.

PMID:
28069987
10.

Deceleration of a Supersonic Beam of SrF Molecules to 120 m s-1.

Mathavan SC, Zapara A, Esajas Q, Hoekstra S.

Chemphyschem. 2016 Nov 18;17(22):3709-3713. doi: 10.1002/cphc.201600813. Epub 2016 Oct 28.

PMID:
27791326
11.

Sex differences in DNA methylation and expression in zebrafish brain: a test of an extended 'male sex drive' hypothesis.

Chatterjee A, Lagisz M, Rodger EJ, Zhen L, Stockwell PA, Duncan EJ, Horsfield JA, Jeyakani J, Mathavan S, Ozaki Y, Nakagawa S.

Gene. 2016 Sep 30;590(2):307-16. doi: 10.1016/j.gene.2016.05.042. Epub 2016 May 31.

12.

Intramammary Immunization of Pregnant Mice with Staphylococcal Protein A Reduces the Post-Challenge Mammary Gland Bacterial Load but Not Pathology.

Gogoi-Tiwari J, Williams V, Waryah CB, Mathavan S, Tiwari HK, Costantino P, Mukkur T.

PLoS One. 2016 Feb 10;11(2):e0148383. doi: 10.1371/journal.pone.0148383. eCollection 2016.

13.
14.

Deep sequencing of small RNA facilitates tissue and sex associated microRNA discovery in zebrafish.

Vaz C, Wee CW, Lee GP, Ingham PW, Tanavde V, Mathavan S.

BMC Genomics. 2015 Nov 16;16:950. doi: 10.1186/s12864-015-2135-7.

15.

Genome-wide mapping of Hif-1α binding sites in zebrafish.

Greenald D, Jeyakani J, Pelster B, Sealy I, Mathavan S, van Eeden FJ.

BMC Genomics. 2015 Nov 11;16:923. doi: 10.1186/s12864-015-2169-x.

16.

The role of the bile acid chenodeoxycholic acid in the targeted oral delivery of the anti-diabetic drug gliclazide, and its applications in type 1 diabetes.

Mathavan S, Chen-Tan N, Arfuso F, Al-Salami H.

Artif Cells Nanomed Biotechnol. 2016 Sep;44(6):1508-19. doi: 10.3109/21691401.2015.1058807. Epub 2015 Jul 25.

PMID:
26212118
17.

Zebrafish Rnf111 is encoded by multiple transcripts and is required for epiboly progression and prechordal plate development.

Bessarab DA, Mathavan S, Jones CM, Ray Dunn N.

Differentiation. 2015 Jan-Feb;89(1-2):22-30. doi: 10.1016/j.diff.2014.12.004. Epub 2015 Jan 22.

PMID:
25619648
18.
19.

Functional mapping of the zebrafish early embryo proteome and transcriptome.

Alli Shaik A, Wee S, Li RH, Li Z, Carney TJ, Mathavan S, Gunaratne J.

J Proteome Res. 2014 Dec 5;13(12):5536-50. doi: 10.1021/pr5005136. Epub 2014 Sep 26.

PMID:
25230361
20.

Impaired development of neural-crest cell-derived organs and intellectual disability caused by MED13L haploinsufficiency.

Utami KH, Winata CL, Hillmer AM, Aksoy I, Long HT, Liany H, Chew EG, Mathavan S, Tay SK, Korzh V, Sarda P, Davila S, Cacheux V.

Hum Mutat. 2014 Nov;35(11):1311-20. doi: 10.1002/humu.22636. Epub 2014 Sep 23. Review.

PMID:
25137640
21.

Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics.

Mooranian A, Negrulj R, Mathavan S, Martinez J, Sciarretta J, Chen-Tan N, Mukkur T, Mikov M, Lalic-Popovic M, Stojančević M, Golocorbin-Kon S, Al-Salami H.

J Pharm Innov. 2014;9:150-157.

22.

An advanced microencapsulated system: a platform for optimized oral delivery of antidiabetic drug-bile acid formulations.

Mooranian A, Negrulj R, Mathavan S, Martinez J, Sciarretta J, Chen-Tan N, Mukkur TK, Mikov M, Lalic-Popovic M, Stojancevic M, Golocorbin-Kon S, Al-Salami H.

Pharm Dev Technol. 2015;20(6):702-9. doi: 10.3109/10837450.2014.915570. Epub 2014 May 5.

PMID:
24798888
23.

Normalization of RNA-sequencing data from samples with varying mRNA levels.

Aanes H, Winata C, Moen LF, Østrup O, Mathavan S, Collas P, Rognes T, Aleström P.

PLoS One. 2014 Feb 25;9(2):e89158. doi: 10.1371/journal.pone.0089158. eCollection 2014.

24.

Transcriptomic analysis of a transgenic zebrafish hepatocellular carcinoma model reveals a prominent role of immune responses in tumour progression and regression.

Li Z, Luo H, Li C, Huo X, Yan C, Huang X, Al-Haddawi M, Mathavan S, Gong Z.

Int J Cancer. 2014 Oct 1;135(7):1564-73. doi: 10.1002/ijc.28794. Epub 2014 Mar 4.

25.

Genome wide expression profiling during spinal cord regeneration identifies comprehensive cellular responses in zebrafish.

Hui SP, Sengupta D, Lee SG, Sen T, Kundu S, Mathavan S, Ghosh S.

PLoS One. 2014 Jan 20;9(1):e84212. doi: 10.1371/journal.pone.0084212. eCollection 2014.

26.

SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy.

See K, Yadav P, Giegerich M, Cheong PS, Graf M, Vyas H, Lee SG, Mathavan S, Fischer U, Sendtner M, Winkler C.

Hum Mol Genet. 2014 Apr 1;23(7):1754-70. doi: 10.1093/hmg/ddt567. Epub 2013 Nov 11.

PMID:
24218366
27.

Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish.

Winata CL, Kondrychyn I, Kumar V, Srinivasan KG, Orlov Y, Ravishankar A, Prabhakar S, Stanton LW, Korzh V, Mathavan S.

PLoS Genet. 2013 Oct;9(10):e1003852. doi: 10.1371/journal.pgen.1003852. Epub 2013 Oct 31.

28.

Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: transcriptomic, histological and targeted gene expression analyses.

Lam SH, Ung CY, Hlaing MM, Hu J, Li ZH, Mathavan S, Gong Z.

Biochim Biophys Acta. 2013 Oct;1830(10):4778-89. doi: 10.1016/j.bbagen.2013.06.008. Epub 2013 Jun 17.

PMID:
23791553
29.

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.

Chowdhury R, Candela-Lena JI, Chan MC, Greenald DJ, Yeoh KK, Tian YM, McDonough MA, Tumber A, Rose NR, Conejo-Garcia A, Demetriades M, Mathavan S, Kawamura A, Lee MK, van Eeden F, Pugh CW, Ratcliffe PJ, Schofield CJ.

ACS Chem Biol. 2013 Jul 19;8(7):1488-96. doi: 10.1021/cb400088q. Epub 2013 Jun 12.

PMID:
23683440
30.

Differential transcript isoform usage pre- and post-zygotic genome activation in zebrafish.

Aanes H, Østrup O, Andersen IS, Moen LF, Mathavan S, Collas P, Alestrom P.

BMC Genomics. 2013 May 15;14:331. doi: 10.1186/1471-2164-14-331.

31.

Dorsal activity of maternal squint is mediated by a non-coding function of the RNA.

Lim S, Kumari P, Gilligan P, Quach HN, Mathavan S, Sampath K.

Development. 2012 Aug;139(16):2903-15. doi: 10.1242/dev.077081. Epub 2012 Jun 21.

32.

Epigenetic complexity during the zebrafish mid-blastula transition.

Andersen IS, Ostrup O, Lindeman LC, Aanes H, Reiner AH, Mathavan S, Aleström P, Collas P.

Biochem Biophys Res Commun. 2012 Jan 27;417(4):1139-44. doi: 10.1016/j.bbrc.2011.12.077. Epub 2011 Dec 22.

PMID:
22209792
33.

Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish.

Lam SH, Hlaing MM, Zhang X, Yan C, Duan Z, Zhu L, Ung CY, Mathavan S, Ong CN, Gong Z.

PLoS One. 2011;6(12):e28273. doi: 10.1371/journal.pone.0028273. Epub 2011 Dec 14.

34.

Prepatterning of developmental gene expression by modified histones before zygotic genome activation.

Lindeman LC, Andersen IS, Reiner AH, Li N, Aanes H, Østrup O, Winata C, Mathavan S, Müller F, Aleström P, Collas P.

Dev Cell. 2011 Dec 13;21(6):993-1004. doi: 10.1016/j.devcel.2011.10.008. Epub 2011 Dec 1.

35.

Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: histological, gene set enrichment and expression analyses.

Sukardi H, Zhang X, Lui EY, Ung CY, Mathavan S, Gong Z, Lam SH.

Biochim Biophys Acta. 2012 Jan;1820(1):33-43. doi: 10.1016/j.bbagen.2011.10.009. Epub 2011 Oct 25.

PMID:
22047996
36.

Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1).

Gupta A, Nagilla P, Le HS, Bunney C, Zych C, Thalamuthu A, Bar-Joseph Z, Mathavan S, Ayyavoo V.

PLoS One. 2011;6(7):e22730. doi: 10.1371/journal.pone.0022730. Epub 2011 Jul 28. Retraction in: PLoS One. 2012;7(8). doi: 10.1371/annotation/d28d38b2-41a3-42a6-b421-68f9460a676d.

37.

A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish.

Nguyen AT, Emelyanov A, Koh CH, Spitsbergen JM, Lam SH, Mathavan S, Parinov S, Gong Z.

Dis Model Mech. 2011 Nov;4(6):801-13. doi: 10.1242/dmm.007831. Epub 2011 Jul 4.

38.

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines.

Lam SH, Lee SG, Lin CY, Thomsen JS, Fu PY, Murthy KR, Li H, Govindarajan KR, Nick LC, Bourque G, Gong Z, Lufkin T, Liu ET, Mathavan S.

BMC Med Genomics. 2011 May 16;4:41. doi: 10.1186/1755-8794-4-41.

39.

Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition.

Aanes H, Winata CL, Lin CH, Chen JP, Srinivasan KG, Lee SG, Lim AY, Hajan HS, Collas P, Bourque G, Gong Z, Korzh V, Aleström P, Mathavan S.

Genome Res. 2011 Aug;21(8):1328-38. doi: 10.1101/gr.116012.110. Epub 2011 May 9.

40.

Tiling histone H3 lysine 4 and 27 methylation in zebrafish using high-density microarrays.

Lindeman LC, Reiner AH, Mathavan S, Aleström P, Collas P.

PLoS One. 2010 Dec 20;5(12):e15651. doi: 10.1371/journal.pone.0015651.

41.

Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa.

Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U.

Hum Mol Genet. 2011 Jan 15;20(2):368-77. doi: 10.1093/hmg/ddq473. Epub 2010 Nov 3.

PMID:
21051334
42.

Morphological and molecular evidence for functional organization along the rostrocaudal axis of the adult zebrafish intestine.

Wang Z, Du J, Lam SH, Mathavan S, Matsudaira P, Gong Z.

BMC Genomics. 2010 Jun 22;11:392. doi: 10.1186/1471-2164-11-392.

43.

Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation.

Ung CY, Lam SH, Hlaing MM, Winata CL, Korzh S, Mathavan S, Gong Z.

BMC Genomics. 2010 Mar 30;11:212. doi: 10.1186/1471-2164-11-212.

44.

Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos.

Lindeman LC, Winata CL, Aanes H, Mathavan S, Alestrom P, Collas P.

Int J Dev Biol. 2010;54(5):803-13. doi: 10.1387/ijdb.103081ll.

45.

Zebrafish spotted-microarray for genome-wide expression profiling experiments. Part I: array printing and hybridization.

Lam SH, Mathavan S, Gong Z.

Methods Mol Biol. 2009;546:175-95. doi: 10.1007/978-1-60327-977-2_12.

PMID:
19378105
46.

Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology.

Lam SH, Mathavan S, Tong Y, Li H, Karuturi RK, Wu Y, Vega VB, Liu ET, Gong Z.

PLoS Genet. 2008 Jul 11;4(7):e1000121. doi: 10.1371/journal.pgen.1000121.

47.

Genomewide expression analysis in zebrafish mind bomb alleles with pancreas defects of different severity identifies putative Notch responsive genes.

Hegde A, Qiu NC, Qiu X, Ho SH, Tay KQ, George J, Ng FS, Govindarajan KR, Gong Z, Mathavan S, Jiang YJ.

PLoS One. 2008 Jan 23;3(1):e1479. doi: 10.1371/journal.pone.0001479.

48.

Genomewide expression profiling in the zebrafish embryo identifies target genes regulated by Hedgehog signaling during vertebrate development.

Xu J, Srinivas BP, Tay SY, Mak A, Yu X, Lee SG, Yang H, Govindarajan KR, Leong B, Bourque G, Mathavan S, Roy S.

Genetics. 2006 Oct;174(2):735-52. Epub 2006 Aug 3.

49.

Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver.

Lam SH, Winata CL, Tong Y, Korzh S, Lim WS, Korzh V, Spitsbergen J, Mathavan S, Miller LD, Liu ET, Gong Z.

Physiol Genomics. 2006 Nov 27;27(3):351-61. Epub 2006 Aug 1.

PMID:
16882884
50.

Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression.

Lam SH, Wu YL, Vega VB, Miller LD, Spitsbergen J, Tong Y, Zhan H, Govindarajan KR, Lee S, Mathavan S, Murthy KR, Buhler DR, Liu ET, Gong Z.

Nat Biotechnol. 2006 Jan;24(1):73-5. Epub 2005 Dec 4.

PMID:
16327811

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