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Items: 1 to 50 of 52

1.

Accessing chemical diversity from the uncultivated symbionts of small marine animals.

Smith TE, Pond CD, Pierce E, Harmer ZP, Kwan J, Zachariah MM, Harper MK, Wyche TP, Matainaho TK, Bugni TS, Barrows LR, Ireland CM, Schmidt EW.

Nat Chem Biol. 2018 Feb;14(2):179-185. doi: 10.1038/nchembio.2537. Epub 2018 Jan 1.

2.

Traditional Preparations and Methanol Extracts of Medicinal Plants from Papua New Guinea Exhibit Similar Cytochrome P450 Inhibition.

Larson EC, Pond CD, Rai PP, Matainaho TK, Piskaut P, Franklin MR, Barrows LR.

Evid Based Complement Alternat Med. 2016;2016:7869710. doi: 10.1155/2016/7869710. Epub 2016 Aug 24.

3.

Structures of Nahuoic Acids B-E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A.

Williams DE, Izard F, Arnould S, Dalisay DS, Tantapakul C, Maneerat W, Matainaho T, Julien E, Andersen RJ.

J Org Chem. 2016 Feb 19;81(4):1324-32. doi: 10.1021/acs.joc.5b02569. Epub 2016 Feb 1.

PMID:
26815947
4.

Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab')2 and whole IgG antivenoms.

Herrera M, de Cássia de O Collaço R, Villalta M, Segura Á, Vargas M, Wright CE, Paiva OK, Matainaho T, Jensen SD, León G, Williams DJ, Rodrigues-Simioni L, Gutiérrez JM.

Toxicol Lett. 2016 Jan 22;241:175-83. doi: 10.1016/j.toxlet.2015.11.020. Epub 2015 Nov 24.

PMID:
26621539
5.

An ethnobotanical survey of medicinal plants used in the East Sepik province of Papua New Guinea.

Koch M, Kehop DA, Kinminja B, Sabak M, Wavimbukie G, Barrows KM, Matainaho TK, Barrows LR, Rai PP.

J Ethnobiol Ethnomed. 2015 Nov 14;11:79. doi: 10.1186/s13002-015-0065-8.

6.

Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.

Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J.

J Nat Prod. 2015 Oct 23;78(10):2411-22. doi: 10.1021/acs.jnatprod.5b00489. Epub 2015 Oct 14.

7.

Isolation of pyrrolocins A-C: cis- and trans-decalin tetramic acid antibiotics from an endophytic fungal-derived pathway.

Jadulco RC, Koch M, Kakule TB, Schmidt EW, Orendt A, He H, Janso JE, Carter GT, Larson EC, Pond C, Matainaho TK, Barrows LR.

J Nat Prod. 2014 Nov 26;77(11):2537-44. doi: 10.1021/np500617u. Epub 2014 Oct 29.

8.

Mooreamide A: a cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii.

Mevers E, Matainaho T, Allara' M, Di Marzo V, Gerwick WH.

Lipids. 2014 Nov;49(11):1127-32. doi: 10.1007/s11745-014-3949-9. Epub 2014 Sep 10.

PMID:
25204580
9.

Interactions of Papua New Guinea medicinal plant extracts with antiretroviral therapy.

Larson EC, Hathaway LB, Lamb JG, Pond CD, Rai PP, Matainaho TK, Piskaut P, Barrows LR, Franklin MR.

J Ethnopharmacol. 2014 Sep 29;155(3):1433-40. doi: 10.1016/j.jep.2014.07.023. Epub 2014 Aug 17.

10.

High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity.

Walter GM, Raveh A, Mok SA, McQuade TJ, Arevang CJ, Schultz PJ, Smith MC, Asare S, Cruz PG, Wisen S, Matainaho T, Sherman DH, Gestwicki JE.

Chem Biol Drug Des. 2014 Apr;83(4):440-9. doi: 10.1111/cbdd.12259.

11.

4-Quinolone alkaloids from Melochia odorata.

Jadulco RC, Pond CD, Van Wagoner RM, Koch M, Gideon OG, Matainaho TK, Piskaut P, Barrows LR.

J Nat Prod. 2014 Jan 24;77(1):183-7. doi: 10.1021/np400847t. Epub 2014 Jan 7.

12.

Myristicyclins A and B: antimalarial procyanidins from Horsfieldia spicata from Papua New Guinea.

Lu Z, Van Wagoner RM, Pond CD, Pole AR, Jensen JB, Blankenship D, Grimberg BT, Kiapranis R, Matainaho TK, Barrows LR, Ireland CM.

Org Lett. 2014 Jan 17;16(2):346-9. doi: 10.1021/ol4022639. Epub 2013 Dec 19.

13.

Discovery of potent broad spectrum antivirals derived from marine actinobacteria.

Raveh A, Delekta PC, Dobry CJ, Peng W, Schultz PJ, Blakely PK, Tai AW, Matainaho T, Irani DN, Sherman DH, Miller DJ.

PLoS One. 2013 Dec 5;8(12):e82318. doi: 10.1371/journal.pone.0082318. eCollection 2013.

14.

Plakinamine M, a steroidal alkaloid from the marine sponge Corticium sp.

Lu Z, Koch M, Harper MK, Matainaho TK, Barrows LR, Van Wagoner RM, Ireland CM.

J Nat Prod. 2013 Nov 22;76(11):2150-2. doi: 10.1021/np400649e. Epub 2013 Nov 6.

15.

Single-molecule inhibition of human kinesin by adociasulfate-13 and -14 from the sponge Cladocroce aculeata.

Smith TE, Hong W, Zachariah MM, Harper MK, Matainaho TK, Van Wagoner RM, Ireland CM, Vershinin M.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18880-5. doi: 10.1073/pnas.1314132110. Epub 2013 Nov 4.

16.

Characterization of the bafilomycin biosynthetic gene cluster from Streptomyces lohii.

Zhang W, Fortman JL, Carlson JC, Yan J, Liu Y, Bai F, Guan W, Jia J, Matainaho T, Sherman DH, Li S.

Chembiochem. 2013 Feb 11;14(3):301-6. doi: 10.1002/cbic.201200743. Epub 2013 Jan 29.

17.

Nahuoic acid A produced by a Streptomyces sp. isolated from a marine sediment is a selective SAM-competitive inhibitor of the histone methyltransferase SETD8.

Williams DE, Dalisay DS, Li F, Amphlett J, Maneerat W, Chavez MA, Wang YA, Matainaho T, Yu W, Brown PJ, Arrowsmith CH, Vedadi M, Andersen RJ.

Org Lett. 2013 Jan 18;15(2):414-7. doi: 10.1021/ol303416k. Epub 2012 Dec 28.

PMID:
23272941
18.

An ethnobotanical survey of medicinal plants used in the eastern highlands of Papua New Guinea.

Jorim RY, Korape S, Legu W, Koch M, Barrows LR, Matainaho TK, Rai PP.

J Ethnobiol Ethnomed. 2012 Dec 18;8:47. doi: 10.1186/1746-4269-8-47.

19.

Snake venomics of two poorly known Hydrophiinae: Comparative proteomics of the venoms of terrestrial Toxicocalamus longissimus and marine Hydrophis cyanocinctus.

Calvete JJ, Ghezellou P, Paiva O, Matainaho T, Ghassempour A, Goudarzi H, Kraus F, Sanz L, Williams DJ.

J Proteomics. 2012 Jul 16;75(13):4091-101. doi: 10.1016/j.jprot.2012.05.026. Epub 2012 May 27.

PMID:
22643073
20.

Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria.

Nunnery JK, Engene N, Byrum T, Cao Z, Jabba SV, Pereira AR, Matainaho T, Murray TF, Gerwick WH.

J Org Chem. 2012 May 4;77(9):4198-208. doi: 10.1021/jo300160e. Epub 2012 Apr 19.

21.

Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: role of neurotoxic and procoagulant effects in venom toxicity.

Herrera M, Fernández J, Vargas M, Villalta M, Segura Á, León G, Angulo Y, Paiva O, Matainaho T, Jensen SD, Winkel KD, Calvete JJ, Williams DJ, Gutiérrez JM.

J Proteomics. 2012 Apr 3;75(7):2128-40. doi: 10.1016/j.jprot.2012.01.006. Epub 2012 Jan 14.

PMID:
22266484
22.

Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov.

Malloy KL, Suyama TL, Engene N, Debonsi H, Cao Z, Matainaho T, Spadafora C, Murray TF, Gerwick WH.

J Nat Prod. 2012 Jan 27;75(1):60-6. doi: 10.1021/np200611f. Epub 2011 Dec 12.

23.

Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction.

Malloy KL, Choi H, Fiorilla C, Valeriote FA, Matainaho T, Gerwick WH.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):683-8. doi: 10.1016/j.bmcl.2011.10.054. Epub 2011 Oct 24.

24.

An ethnobotanical survey of medicinal plants used in the Siwai and Buin districts of the Autonomous Region of Bougainville.

Waruruai J, Sipana B, Koch M, Barrows LR, Matainaho TK, Rai PP.

J Ethnopharmacol. 2011 Nov 18;138(2):564-77. doi: 10.1016/j.jep.2011.09.052. Epub 2011 Oct 6.

25.

Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment.

Williams DE, Dalisay DS, Patrick BO, Matainaho T, Andrusiak K, Deshpande R, Myers CL, Piotrowski JS, Boone C, Yoshida M, Andersen RJ.

Org Lett. 2011 Aug 5;13(15):3936-9. doi: 10.1021/ol2014494. Epub 2011 Jul 12.

26.

Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea.

Vargas M, Segura A, Herrera M, Villalta M, Estrada R, Cerdas M, Paiva O, Matainaho T, Jensen SD, Winkel KD, León G, Gutiérrez JM, Williams DJ.

PLoS Negl Trop Dis. 2011 May;5(5):e1144. doi: 10.1371/journal.pntd.0001144. Epub 2011 May 17.

27.

New antimycobacterial triterpenoids from Rhus taitensis.

Jadulco RC, Koch M, Van Wagoner RM, Pond C, Gideon OG, Matainaho T, Piskaut P, Barrows LR.

Planta Med. 2011 Sep;77(14):1651-4. doi: 10.1055/s-0030-1271027. Epub 2011 May 3.

PMID:
21544777
28.

Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua New Guinea marine cyanobacterium.

Malloy KL, Villa FA, Engene N, Matainaho T, Gerwick L, Gerwick WH.

J Nat Prod. 2011 Jan 28;74(1):95-8. doi: 10.1021/np1005407. Epub 2010 Dec 14.

29.

The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria.

Choi H, Pereira AR, Cao Z, Shuman CF, Engene N, Byrum T, Matainaho T, Murray TF, Mangoni A, Gerwick WH.

J Nat Prod. 2010 Aug 27;73(8):1411-21. doi: 10.1021/np100468n.

30.

Making the most of Papua New Guinea's biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in "The Land of the Unexpected"

Barrows LR, Matainaho TK, Ireland CM, Miller S, Carter GT, Bugni T, Rai P, Gideon O, Manoka B, Piskaut P, Banka R, Kiapranis R, Noro JN, Pond CD, Andjelic CD, Koch M, Harper MK, Powan E, Pole AR, Jensen JB.

Pharm Biol. 2009 Aug 1;47(8):795-808.

31.

Alotaketals A and B, sesterterpenoids from the marine sponge Hamigera species that activate the cAMP cell signaling pathway.

Forestieri R, Merchant CE, de Voogd NJ, Matainaho T, Kieffer TJ, Andersen RJ.

Org Lett. 2009 Nov 19;11(22):5166-9. doi: 10.1021/ol902066e.

PMID:
19873990
32.

The aignopsanes, a new class of sesquiterpenes from selected chemotypes of the sponge Cacospongia mycofijiensis.

Johnson TA, Amagata T, Sashidhara KV, Oliver AG, Tenney K, Matainaho T, Ang KK, McKerrow JH, Crews P.

Org Lett. 2009 May 7;11(9):1975-8. doi: 10.1021/ol900446d.

33.

Consumption of guava (Psidium guajava L) and noni (Morinda citrifolia L) may protect betel quid-chewing Papua New Guineans against diabetes.

Owen PL, Martineau LC, Caves D, Haddad PS, Matainaho T, Johns T.

Asia Pac J Clin Nutr. 2008;17(4):635-43.

34.

Scalarane-based metabolites isolated from the antimitotic extract of the marine sponge Hyrtios erectus.

Díaz-Marrero AR, Matainaho T, van Soest R, Roberge M, Andersen RJ.

Nat Prod Res. 2008;22(15):1304-9. doi: 10.1080/14786410701824023.

PMID:
19023786
35.

Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis.

Noro JC, Barrows LR, Gideon OG, Ireland CM, Koch M, Matainaho T, Piskaut P, Pond CD, Bugni TS.

J Nat Prod. 2008 Sep;71(9):1623-4. doi: 10.1021/np800082e. Epub 2008 Aug 19.

36.

Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum.

Clark BR, Engene N, Teasdale ME, Rowley DC, Matainaho T, Valeriote FA, Gerwick WH.

J Nat Prod. 2008 Sep;71(9):1530-7. doi: 10.1021/np800088a. Epub 2008 Aug 13.

37.

Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida.

Gutiérrez M, Suyama TL, Engene N, Wingerd JS, Matainaho T, Gerwick WH.

J Nat Prod. 2008 Jun;71(6):1099-103. doi: 10.1021/np800121a. Epub 2008 Apr 30.

PMID:
18444683
38.

Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.

Linington RG, Edwards DJ, Shuman CF, McPhail KL, Matainaho T, Gerwick WH.

J Nat Prod. 2008 Jan;71(1):22-7. doi: 10.1021/np070280x. Epub 2007 Dec 29.

39.

Tauramamide, a lipopeptide antibiotic produced in culture by Brevibacillus laterosporus isolated from a marine habitat: structure elucidation and synthesis.

Desjardine K, Pereira A, Wright H, Matainaho T, Kelly M, Andersen RJ.

J Nat Prod. 2007 Dec;70(12):1850-3. Epub 2007 Nov 29.

PMID:
18044840
40.

Protein phosphatase inhibitors isolated from Spongia irregularis collected in Papua New Guinea.

Carr G, Raszek M, Van Soest R, Matainaho T, Shopik M, Holmes CF, Andersen RJ.

J Nat Prod. 2007 Nov;70(11):1812-5. Epub 2007 Nov 3.

PMID:
17979246
41.
42.

Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus.

Nun TK, Kroll DJ, Oberlies NH, Soejarto DD, Case RJ, Piskaut P, Matainaho T, Hilscher C, Wang L, Dittmer DP, Gao SJ, Damania B.

Mol Cancer Ther. 2007 Aug;6(8):2360-70.

43.

Anti-TB activity of Evodia elleryana bark extract.

Barrows LR, Powan E, Pond CD, Matainaho T.

Fitoterapia. 2007 Apr;78(3):250-2. Epub 2007 Feb 3.

44.

A serendipitous discovery of isomotuporin-containing sponge populations of Theonella swinhoei.

Wegerski CJ, Hammond J, Tenney K, Matainaho T, Crews P.

J Nat Prod. 2007 Jan;70(1):89-94.

45.

Exiguamine A, an indoleamine-2,3-dioxygenase (IDO) inhibitor isolated from the marine sponge Neopetrosia exigua.

Brastianos HC, Vottero E, Patrick BO, Van Soest R, Matainaho T, Mauk AG, Andersen RJ.

J Am Chem Soc. 2006 Dec 20;128(50):16046-7.

PMID:
17165752
46.

Avinosol, a meroterpenoid-nucleoside conjugate with antiinvasion activity isolated from the marine sponge Dysidea sp.

Diaz-Marrero AR, Austin P, Van Soest R, Matainaho T, Roskelley CD, Roberge M, Andersen RJ.

Org Lett. 2006 Aug 17;8(17):3749-52.

PMID:
16898808
47.

Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells.

Williams DE, Austin P, Diaz-Marrero AR, Soest RV, Matainaho T, Roskelley CD, Roberge M, Andersen RJ.

Org Lett. 2005 Sep 15;7(19):4173-6.

PMID:
16146380
48.

Bidirectional ion transport in thyroid: secretion of anions by monolayer cultures that absorb sodium.

Armstrong J, Matainaho T, Cragoe EJ Jr, Huxham GJ, Bourke JR, Manley SW.

Am J Physiol. 1992 Jan;262(1 Pt 1):E40-5.

PMID:
1733249
49.
50.

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