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Items: 38

1.

Live cell optical assay for precise characterization of receptors coupling to Gα12.

Masuho I, Skamangas NK, Martemyanov KA.

Basic Clin Pharmacol Toxicol. 2019 Mar 27. doi: 10.1111/bcpt.13228. [Epub ahead of print]

PMID:
30916867
2.

Author Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.

Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y.

Sci Rep. 2019 Mar 9;9(1):4523. doi: 10.1038/s41598-018-37932-6.

3.

Molecular Deconvolution Platform to Establish Disease Mechanisms by Surveying GPCR Signaling.

Masuho I, Chavali S, Muntean BS, Skamangas NK, Simonyan K, Patil DN, Kramer GM, Ozelius L, Babu MM, Martemyanov KA.

Cell Rep. 2018 Jul 17;24(3):557-568.e5. doi: 10.1016/j.celrep.2018.06.080.

4.

PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.

Desbois M, Crawley O, Evans PR, Baker ST, Masuho I, Yasuda R, Grill B.

J Biol Chem. 2018 Sep 7;293(36):13897-13909. doi: 10.1074/jbc.RA118.002176. Epub 2018 Jul 11.

PMID:
29997255
5.

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.

Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K.

Nat Commun. 2018 May 18;9(1):1996. doi: 10.1038/s41467-018-04432-0.

6.

RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.

Qutob N, Masuho I, Alon M, Emmanuel R, Cohen I, Di Pizio A, Madore J, Elkahloun A, Ziv T, Levy R, Gartner JJ, Hill VK, Lin JC, Hevroni Y, Greenberg P, Brodezki A, Rosenberg SA, Kosloff M, Hayward NK, Admon A, Niv MY, Scolyer RA, Martemyanov KA, Samuels Y.

Sci Rep. 2018 Jan 12;8(1):653. doi: 10.1038/s41598-017-18851-4. Erratum in: Sci Rep. 2019 Mar 9;9(1):4523.

7.

Pharmacogenomics of GPCR Drug Targets.

Hauser AS, Chavali S, Masuho I, Jahn LJ, Martemyanov KA, Gloriam DE, Babu MM.

Cell. 2018 Jan 11;172(1-2):41-54.e19. doi: 10.1016/j.cell.2017.11.033. Epub 2017 Dec 14.

8.

Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila.

Himmelreich S, Masuho I, Berry JA, MacMullen C, Skamangas NK, Martemyanov KA, Davis RL.

Cell Rep. 2017 Nov 21;21(8):2074-2081. doi: 10.1016/j.celrep.2017.10.108.

9.

LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.

Carmon KS, Gong X, Yi J, Wu L, Thomas A, Moore CM, Masuho I, Timson DJ, Martemyanov KA, Liu QJ.

J Biol Chem. 2017 Sep 8;292(36):14989-15001. doi: 10.1074/jbc.M117.786798. Epub 2017 Jul 24.

10.

Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans.

Lohmann K, Masuho I, Patil DN, Baumann H, Hebert E, Steinrücke S, Trujillano D, Skamangas NK, Dobricic V, Hüning I, Gillessen-Kaesbach G, Westenberger A, Savic-Pavicevic D, Münchau A, Oprea G, Klein C, Rolfs A, Martemyanov KA.

Hum Mol Genet. 2017 Mar 15;26(6):1078-1086. doi: 10.1093/hmg/ddx018.

11.

GNB5 mutation causes a novel neuropsychiatric disorder featuring attention deficit hyperactivity disorder, severely impaired language development and normal cognition.

Shamseldin HE, Masuho I, Alenizi A, Alyamani S, Patil DN, Ibrahim N, Martemyanov KA, Alkuraya FS.

Genome Biol. 2016 Sep 27;17(1):195.

12.

Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.

Chen Y, Palczewska G, Masuho I, Gao S, Jin H, Dong Z, Gieser L, Brooks MJ, Kiser PD, Kern TS, Martemyanov KA, Swaroop A, Palczewski K.

Sci Signal. 2016 Jul 26;9(438):ra74. doi: 10.1126/scisignal.aag0245.

13.

Homozygous GNAL mutation associated with familial childhood-onset generalized dystonia.

Masuho I, Fang M, Geng C, Zhang J, Jiang H, Özgul RK, Yılmaz DY, Yalnızoğlu D, Yüksel D, Yarrow A, Myers A, Burn SC, Crotwell PL, Padilla-Lopez S, Dursun A, Martemyanov KA, Kruer MC.

Neurol Genet. 2016 May 12;2(3):e78. doi: 10.1212/NXG.0000000000000078. eCollection 2016 Jun. No abstract available.

14.

Screening of GNAL variants in Brazilian patients with isolated dystonia reveals a novel mutation with partial loss of function.

Dos Santos CO, Masuho I, da Silva-Júnior FP, Barbosa ER, Silva SM, Borges V, Ferraz HB, Rocha MS, Limongi JC, Martemyanov KA, de Carvalho Aguiar P.

J Neurol. 2016 Apr;263(4):665-8. doi: 10.1007/s00415-016-8026-2. Epub 2016 Jan 25.

15.

Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.

Masuho I, Ostrovskaya O, Kramer GM, Jones CD, Xie K, Martemyanov KA.

Sci Signal. 2015 Dec 1;8(405):ra123. doi: 10.1126/scisignal.aab4068.

16.

Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling.

Xie K, Masuho I, Shih CC, Cao Y, Sasaki K, Lai CW, Han PL, Ueda H, Dessauer CW, Ehrlich ME, Xu B, Willardson BM, Martemyanov KA.

Elife. 2015 Nov 27;4. pii: e10451. doi: 10.7554/eLife.10451.

17.

Monitoring G Protein Activation in Cells with BRET.

Masuho I, Martemyanov KA, Lambert NA.

Methods Mol Biol. 2015;1335:107-13. doi: 10.1007/978-1-4939-2914-6_8.

18.

Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain.

Orlandi C, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Martemyanov KA.

J Biol Chem. 2015 May 29;290(22):13622-39. doi: 10.1074/jbc.M115.645374. Epub 2015 Mar 19.

19.

G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization.

Octeau JC, Schrader JM, Masuho I, Sharma M, Aiudi C, Chen CK, Kovoor A, Celver J.

PLoS One. 2014 Aug 27;9(8):e105791. doi: 10.1371/journal.pone.0105791. eCollection 2014.

20.

RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.

Ostrovskaya O, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Wickman K, Martemyanov KA.

Elife. 2014 Apr 22;3:e02053. doi: 10.7554/eLife.02053.

21.

Mutations in GNAL: a novel cause of craniocervical dystonia.

Kumar KR, Lohmann K, Masuho I, Miyamoto R, Ferbert A, Lohnau T, Kasten M, Hagenah J, Brüggemann N, Graf J, Münchau A, Kostic VS, Sue CM, Domingo AR, Rosales RL, Lee LV, Freimann K, Westenberger A, Mukai Y, Kawarai T, Kaji R, Klein C, Martemyanov KA, Schmidt A.

JAMA Neurol. 2014 Apr;71(4):490-4. doi: 10.1001/jamaneurol.2013.4677.

22.

Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability.

Posokhova E, Ng D, Opel A, Masuho I, Tinker A, Biesecker LG, Wickman K, Martemyanov KA.

PLoS One. 2013 Oct 29;8(10):e76973. doi: 10.1371/journal.pone.0076973. eCollection 2013.

23.

Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells.

Masuho I, Xie K, Martemyanov KA.

J Biol Chem. 2013 Aug 30;288(35):25129-42. doi: 10.1074/jbc.M113.462283. Epub 2013 Jul 15.

24.

Mutations in GNAL cause primary torsion dystonia.

Fuchs T, Saunders-Pullman R, Masuho I, Luciano MS, Raymond D, Factor S, Lang AE, Liang TW, Trosch RM, White S, Ainehsazan E, Hervé D, Sharma N, Ehrlich ME, Martemyanov KA, Bressman SB, Ozelius LJ.

Nat Genet. 2013 Jan;45(1):88-92. doi: 10.1038/ng.2496. Epub 2012 Dec 9.

25.

The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum.

Xie K, Masuho I, Brand C, Dessauer CW, Martemyanov KA.

Sci Signal. 2012 Aug 28;5(239):ra63. doi: 10.1126/scisignal.2002922.

26.

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.

Orlandi C, Posokhova E, Masuho I, Ray TA, Hasan N, Gregg RG, Martemyanov KA.

J Cell Biol. 2012 Jun 11;197(6):711-9. doi: 10.1083/jcb.201202123.

27.

Interaction of transducin with uncoordinated 119 protein (UNC119): implications for the model of transducin trafficking in rod photoreceptors.

Gopalakrishna KN, Doddapuneni K, Boyd KK, Masuho I, Martemyanov KA, Artemyev NO.

J Biol Chem. 2011 Aug 19;286(33):28954-62. doi: 10.1074/jbc.M111.268821. Epub 2011 Jun 28.

28.

Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors.

Masuho I, Wakasugi-Masuho H, Posokhova EN, Patton JR, Martemyanov KA.

J Biol Chem. 2011 Jun 17;286(24):21806-13. doi: 10.1074/jbc.M111.241513. Epub 2011 Apr 21.

29.

Establishment of clonal cell lines of taste buds from a p53(-/-) mouse tongue.

Sako H, Hori M, Masuho I, Saitoh O, Okada A, Tomooka Y.

In Vitro Cell Dev Biol Anim. 2011 Apr;47(4):333-40. doi: 10.1007/s11626-011-9398-3. Epub 2011 Mar 25.

PMID:
21437573
30.

Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons.

Cao Y, Kolesnikov AV, Masuho I, Kefalov VJ, Martemyanov KA.

J Neurosci. 2010 Oct 13;30(41):13784-93. doi: 10.1523/JNEUROSCI.1191-10.2010.

31.

Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling.

Masuho I, Celver J, Kovoor A, Martemyanov KA.

J Biol Chem. 2010 Feb 12;285(7):4781-7. doi: 10.1074/jbc.M109.058511. Epub 2009 Dec 11.

32.

Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons.

Cao Y, Masuho I, Okawa H, Xie K, Asami J, Kammermeier PJ, Maddox DM, Furukawa T, Inoue T, Sampath AP, Martemyanov KA.

J Neurosci. 2009 Jul 22;29(29):9301-13. doi: 10.1523/JNEUROSCI.1367-09.2009.

33.
34.

Characterization of bitter taste responses of intestinal STC-1 cells.

Masuho I, Tateyama M, Saitoh O.

Chem Senses. 2005 May;30(4):281-90. Epub 2005 Mar 1.

PMID:
15741596
35.
36.

Distribution of regulator of G protein signaling 8 (RGS8) protein in the cerebellum.

Saitoh O, Masuho I, Itoh M, Abe H, Komori K, Odagiri M.

Cerebellum. 2003;2(2):154-60.

PMID:
12880183
37.

Regulator of G protein signaling 8 (RGS8) requires its NH2 terminus for subcellular localization and acute desensitization of G protein-gated K+ channels.

Saitoh O, Masuho I, Terakawa I, Nomoto S, Asano T, Kubo Y.

J Biol Chem. 2001 Feb 16;276(7):5052-8. Epub 2000 Nov 21.

38.

Molecular cloning and characterization of Xenopus RGS5.

Saitoh O, Odagiri M, Masuho I, Nomoto S, Kinoshita N.

Biochem Biophys Res Commun. 2000 Apr 2;270(1):34-9.

PMID:
10733901

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