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Items: 1 to 50 of 77

1.
2.

NMDA NR2B subtype-selective receptor antagonists fail to antagonize electrically-precipitated seizures and elicit popping in mice.

Burket JA, Mastropaolo J, Rosse RB, Katz EU, Deutsch SI.

Eur Neuropsychopharmacol. 2010 Mar;20(3):207-10. doi: 10.1016/j.euroneuro.2009.11.008. Epub 2009 Dec 21.

PMID:
20022475
3.

Genetically inbred Balb/C mice are more sensitive to an effect of flurazepam and more resistant to an effect of stress than a genetically outbred mouse strain.

Burket JA, Mastropaolo J, Rosse RB, Deutsch SI.

Epilepsy Behav. 2009 Nov;16(3):415-7. doi: 10.1016/j.yebeh.2009.08.013. Epub 2009 Sep 16.

PMID:
19762285
4.

An epigenetic intervention interacts with genetic strain differences to modulate the stress-induced reduction of flurazepam's antiseizure efficacy in the mouse.

Deutsch SI, Mastropaolo J, Burket JA, Rosse RB.

Eur Neuropsychopharmacol. 2009 Jun;19(6):398-401. doi: 10.1016/j.euroneuro.2008.12.011. Epub 2009 Feb 1.

PMID:
19189880
5.

Expression of NR1, NR2A and NR2B NMDA receptor subunits is not altered in the genetically-inbred Balb/c mouse strain with heightened behavioral sensitivity to MK-801, a noncompetitive NMDA receptor antagonist.

Perera PY, Lichy JH, Mastropaolo J, Rosse RB, Deutsch SI.

Eur Neuropsychopharmacol. 2008 Nov;18(11):814-9. doi: 10.1016/j.euroneuro.2008.06.004. Epub 2008 Jul 31.

PMID:
18674888
6.

Epigenetic therapeutic strategies for the treatment of neuropsychiatric disorders: ready for prime time?

Deutsch SI, Rosse RB, Mastropaolo J, Long KD, Gaskins BL.

Clin Neuropharmacol. 2008 Mar-Apr;31(2):104-19. doi: 10.1097/WNF.0b013e318067e255. Review.

PMID:
18382183
7.

First administration of cytidine diphosphocholine and galantamine in schizophrenia: a sustained alpha7 nicotinic agonist strategy.

Deutsch SI, Schwartz BL, Schooler NR, Rosse RB, Mastropaolo J, Gaskins B.

Clin Neuropharmacol. 2008 Jan-Feb;31(1):34-9. doi: 10.1097/wnf.0b013e31806462ba.

PMID:
18303489
8.

Sodium butyrate, an epigenetic interventional strategy, attenuates a stress-induced alteration of MK-801's pharmacologic action.

Deutsch SI, Rosse RB, Long KD, Gaskins BL, Burket JA, Mastropaolo J.

Eur Neuropsychopharmacol. 2008 Aug;18(8):565-8. doi: 10.1016/j.euroneuro.2007.11.004. Epub 2008 Mar 4.

PMID:
18164185
9.

Guanosine possesses specific modulatory effects on NMDA receptor-mediated neurotransmission in intact mice.

Deutsch SI, Rosse RB, Long KD, Gaskins BL, Mastropaolo J.

Eur Neuropsychopharmacol. 2008 Apr;18(4):299-302. Epub 2007 Sep 4.

PMID:
17804205
10.

Effects of CDP-choline and the combination of CDP-choline and galantamine differ in an animal model of schizophrenia: development of a selective alpha7 nicotinic acetylcholine receptor agonist strategy.

Deutsch SI, Rosse RB, Schwartz BL, Schooler NR, Gaskins BL, Long KD, Mastropaolo J.

Eur Neuropsychopharmacol. 2008 Feb;18(2):147-51. Epub 2007 Jul 26.

PMID:
17656074
11.

Phencyclidine and dizocilpine induced behaviors reduced by N-acetylaspartylglutamate peptidase inhibition via metabotropic glutamate receptors.

Olszewski RT, Wegorzewska MM, Monteiro AC, Krolikowski KA, Zhou J, Kozikowski AP, Long K, Mastropaolo J, Deutsch SI, Neale JH.

Biol Psychiatry. 2008 Jan 1;63(1):86-91. Epub 2007 Jun 27.

12.

Rare neurodevelopmental abnormalities of sarcosinemia may involve glycinergic stimulation of a primed N-methyl-d-aspartate receptor.

Deutsch SI, Rosse RB, Long KD, Gaskins B, Mastropaolo J.

Clin Neuropharmacol. 2006 Nov-Dec;29(6):361-3. Review.

PMID:
17095900
13.

Imitation of facial expressions in schizophrenia.

Schwartz BL, Mastropaolo J, Rosse RB, Mathis G, Deutsch SI.

Psychiatry Res. 2006 Dec 7;145(2-3):87-94. Epub 2006 Oct 30.

PMID:
17074400
14.

Modulatory effects of d-serine and sarcosine on NMDA receptor-mediated neurotransmission are apparent after stress in the genetically inbred BALB/c mouse strain.

Long KD, Mastropaolo J, Rosse RB, Manaye KF, Deutsch SI.

Brain Res Bull. 2006 May 31;69(6):626-30. Epub 2006 Mar 30.

PMID:
16716829
15.

Exogenously administered D-serine failed to potentiate the ability of MK-801 to antagonize electrically precipitated seizures in nonhandled control and stressed mice.

Long KD, Mastropaolo J, Rosse RB, Deutsch SI.

Eur Neuropsychopharmacol. 2007 Jan;17(1):53-7. Epub 2006 Mar 6.

PMID:
16616833
16.

Therapeutic implications of a selective alpha7 nicotinic receptor abnormality in schizophrenia.

Deutsch SI, Rosse RB, Schwartz BL, Weizman A, Chilton M, Arnold DS, Mastropaolo J.

Isr J Psychiatry Relat Sci. 2005;42(1):33-44. Review.

17.

Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome.

Deutsch SI, Long KD, Rosse RB, Mastropaolo J, Eller J.

Clin Neuropharmacol. 2005 Jan-Feb;28(1):28-37. Review.

PMID:
15711436
18.
19.

Behavioral consequences of methyllycaconitine in mice: a model of alpha7 nicotinic acetylcholine receptor deficiency.

Chilton M, Mastropaolo J, Rosse RB, Bellack AS, Deutsch SI.

Life Sci. 2004 May 7;74(25):3133-9.

PMID:
15081578
21.

Modulation of MK-801-elicited mouse popping behavior by galantamine is complex and dose-dependent.

Deutsch SI, Rosse RB, Billingslea EN, Bellack AS, Mastropaolo J.

Life Sci. 2003 Sep 19;73(18):2355-61.

PMID:
12941437
22.

Adjuvant topiramate administration: a pharmacologic strategy for addressing NMDA receptor hypofunction in schizophrenia.

Deutsch SI, Schwartz BL, Rosse RB, Mastropaolo J, Marvel CL, Drapalski AL.

Clin Neuropharmacol. 2003 Jul-Aug;26(4):199-206.

PMID:
12897641
23.

Fluoxetine's effects on cognitive performance in patients with traumatic brain injury.

Horsfield SA, Rosse RB, Tomasino V, Schwartz BL, Mastropaolo J, Deutsch SI.

Int J Psychiatry Med. 2002;32(4):337-44.

PMID:
12779183
24.

Methyllycaconitine fails to inhibit electrically precipitated tonic hindlimb extension in mice.

Deutsch SI, Rosse RB, Bellack AS, Billingslea EN, Mastropaolo J.

Clin Neuropharmacol. 2003 Mar-Apr;26(2):62-4.

PMID:
12671524
25.

Interaction of stress and strain on glutamatergic neurotransmission: relevance to schizophrenia.

Billingslea EN, Mastropaolo J, Rosse RB, Bellack AS, Deutsch SI.

Pharmacol Biochem Behav. 2003 Jan;74(2):351-6.

PMID:
12479954
26.

Topiramate antagonizes MK-801 in an animal model of schizophrenia.

Deutsch SI, Rosse RB, Billingslea EN, Bellack AS, Mastropaolo J.

Eur J Pharmacol. 2002 Aug 2;449(1-2):121-5.

PMID:
12163115
27.

A revised excitotoxic hypothesis of schizophrenia: therapeutic implications.

Deutsch SI, Rosse RB, Schwartz BL, Mastropaolo J.

Clin Neuropharmacol. 2001 Jan-Feb;24(1):43-9. Review.

PMID:
11290881
28.

Stress and a glycinergic intervention interact in the modulation of MK-801-elicited mouse popping behavior.

Deutsch SI, Rosse RB, Schwartz BL, Powell DG, Mastropaolo J.

Pharmacol Biochem Behav. 1999 Feb;62(2):395-8.

PMID:
9972709
29.

Both nicotine and mecamylamine block dizocilpine-induced explosive jumping behavior in mice: psychiatric implications.

Tizabi Y, Mastropaolo J, Park CH, Riggs RL, Powell D, Rosse RB, Deutsch SI.

Psychopharmacology (Berl). 1998 Nov;140(2):202-5.

PMID:
9860111
30.

Neurodevelopmental consequences of early exposure to phencyclidine and related drugs.

Deutsch SI, Mastropaolo J, Rosse RB.

Clin Neuropharmacol. 1998 Nov-Dec;21(6):320-32. Review.

PMID:
9844787
31.

Inbred mouse strains differ in their sensitivity to an antiseizure effect of MK-801.

Deutsch SI, Mastropaolo J, Powell DG, Rosse RB, Bachus SE.

Clin Neuropharmacol. 1998 Jul-Aug;21(4):255-7.

PMID:
9704168
32.

Current status of NMDA antagonist interventions in the treatment of nonketotic hyperglycinemia.

Deutsch SI, Rosse RB, Mastropaolo J.

Clin Neuropharmacol. 1998 Mar-Apr;21(2):71-9. Review.

PMID:
9579291
33.

The antiseizure efficacies of MK-801, phencyclidine, ketamine, and memantine are altered selectively by stress.

Deutsch SI, Mastropaolo J, Riggs RL, Rosse RB.

Pharmacol Biochem Behav. 1997 Nov;58(3):709-12.

PMID:
9329063
34.

Behavioral approaches to the functional assessment of NMDA-mediated neural transmission in intact mice.

Deutsch SI, Rosse RB, Mastropaolo J.

Clin Neuropharmacol. 1997 Oct;20(5):375-84. Review.

PMID:
9331513
35.

Inbred mouse strains differ in sensitivity to "popping" behavior elicited by MK-801.

Deutsch SI, Rosse RB, Paul SM, Riggs RL, Mastropaolo J.

Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):315-7.

PMID:
9164588
36.

Selective effects of MAO inhibition on peripheral benzodiazepine receptor binding in the mouse.

Park CH, Lukacs LG, Mastropaolo J, Deutsch SI.

Isr J Psychiatry Relat Sci. 1997;34(4):300-7.

PMID:
9409087
37.

Evaluation of in vivo interactions in mice between flurazepam and two neuroactive steroids.

Deutsch SI, Rosse RB, Steinberg K, Morn C, Koetzner L, Riggs R, Mastropaolo J.

Pharmacol Biochem Behav. 1996 Nov;55(3):323-6.

PMID:
8951972
38.

The competitive NMDA antagonist CPP blocks MK-801-elicited popping behavior in mice.

Deutsch SI, Rosse RB, Riggs RL, Koetzner L, Mastropaolo J.

Neuropsychopharmacology. 1996 Oct;15(4):329-31.

39.

7-Nitroindazole and methylene blue, inhibitors of neuronal nitric oxide synthase and NO-stimulated guanylate cyclase, block MK-801-elicited behaviors in mice.

Deutsch SI, Rosse RB, Paul SM, Tomasino V, Koetzner L, Morn CB, Mastropaolo J.

Neuropsychopharmacology. 1996 Jul;15(1):37-43.

40.

Selective cyclodextrin inhibition of alfaxolone-induced ataxia.

Koetzner L, Riggs RL, Mastropaolo J, Deutsch SI.

J Pharm Pharmacol. 1996 May;48(5):529-31.

PMID:
8799881
41.

Facilitating role of m-chlorophenylbiguanide in a cocaine discrimination.

Koetzner L, Mastropaolo J, Deutsch SI.

Pharmacol Biochem Behav. 1995 Dec;52(4):815-8.

PMID:
8587924
42.

Computerized measurement of MK-801-elicited popping and hyperactivity in mice.

Rosse RB, Mastropaolo J, Sussman DM, Koetzner L, Morn CB, Deutsch SI.

Clin Neuropharmacol. 1995 Oct;18(5):448-57.

PMID:
8665559
43.

MK-801 alters the GABAA receptor complex and potentiates flurazepam's antiseizure efficacy.

Deutsch SI, Park CH, Lukacs LG, Morn C, Koetzner L, Mastropaolo J.

Pharmacol Biochem Behav. 1995 Aug;51(4):909-15.

PMID:
7675876
44.

Interference with nitric oxide production and action potentiates the antiseizure efficacy of flurazepam.

Deutsch SI, Rosse RB, Morn C, Koetzner L, Mastropaolo J.

Pharmacol Biochem Behav. 1995 May;51(1):133-7.

PMID:
7617724
45.

The effects of adenosine A3 receptor stimulation on seizures in mice.

Von Lubitz DK, Carter MF, Deutsch SI, Lin RC, Mastropaolo J, Meshulam Y, Jacobson KA.

Eur J Pharmacol. 1995 Feb 24;275(1):23-9.

PMID:
7774659
46.

Environmental stress-induced functional modification of the central benzodiazepine binding site.

Deutsch SI, Rosse RB, Mastropaolo J.

Clin Neuropharmacol. 1994 Jun;17(3):205-28. Review.

PMID:
9316667
47.

A glycinergic intervention potentiates the antiseizure efficacies of MK-801, flurazepam, and carbamazepine.

Norris DO, Mastropaolo J, O'Connor DA, Cohen JM, Deutsch SI.

Neurochem Res. 1994 Feb;19(2):161-5.

PMID:
8183425
48.

Discriminative stimulus properties of midazolam are shared by a GABA-receptor positive steroid.

Deutsch SI, Mastropaolo J.

Pharmacol Biochem Behav. 1993 Dec;46(4):963-5.

PMID:
8309977
49.

Glycinergic interventions potentiate the ability of MK 801 to raise the threshold voltage for tonic hindlimb extension in mice.

Norris DO, Mastropaolo J, O'Connor DA, Novitzki MR, Deutsch SI.

Pharmacol Biochem Behav. 1992 Oct;43(2):609-12.

PMID:
1438497
50.

GABA-active steroids: endogenous modulators of GABA-gated chloride ion conductance.

Deutsch SI, Mastropaolo J, Hitri A.

Clin Neuropharmacol. 1992 Oct;15(5):352-64. Review.

PMID:
1330306

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