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Items: 1 to 50 of 121

1.

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses.

Hayman TJ, Hsu AC, Kolesnik TB, Dagley LF, Willemsen J, Tate MD, Baker PJ, Kershaw NJ, Kedzierski L, Webb AI, Wark PA, Kedzierska K, Masters SL, Belz GT, Binder M, Hansbro PM, Nicola NA, Nicholson SE.

Immunol Cell Biol. 2019 Jul 23. doi: 10.1111/imcb.12284. [Epub ahead of print]

PMID:
31335993
2.

Direct Experimental Observation of in situ Dehydrogenation of an Amine-Borane System Using Gas Electron Diffraction.

Ja'o AM, Masters SL, Wann DA, Rankine CD, Nunes JPF, Guillemin JC.

J Phys Chem A. 2019 Aug 15;123(32):7104-7112. doi: 10.1021/acs.jpca.9b05522. Epub 2019 Jul 31.

PMID:
31314528
3.

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm.

Nguyen TA, Smith BRC, Elgass KD, Creed SJ, Cheung S, Tate MD, Belz GT, Wicks IP, Masters SL, Pang KC.

J Immunol. 2019 Jun 15;202(12):3483-3492. doi: 10.4049/jimmunol.1801369. Epub 2019 May 6.

PMID:
31061008
4.

Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes.

Skinner OP, Jurczyluk J, Baker PJ, Masters SL, Rios Wilks AG, Clearwater MS, Robertson AAB, Schroder K, Mehr S, Munoz MA, Rogers MJ.

J Allergy Clin Immunol. 2019 Jun;143(6):2315-2317.e3. doi: 10.1016/j.jaci.2019.02.013. Epub 2019 Feb 21. No abstract available.

5.

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.

Vince JE, De Nardo D, Gao W, Vince AJ, Hall C, McArthur K, Simpson D, Vijayaraj S, Lindqvist LM, Bouillet P, Rizzacasa MA, Man SM, Silke J, Masters SL, Lessene G, Huang DCS, Gray DHD, Kile BT, Shao F, Lawlor KE.

Cell Rep. 2018 Nov 27;25(9):2339-2353.e4. doi: 10.1016/j.celrep.2018.10.103.

6.

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses.

Bierschenk D, Monteleone M, Moghaddas F, Baker PJ, Masters SL, Boucher D, Schroder K.

J Leukoc Biol. 2019 Feb;105(2):401-410. doi: 10.1002/JLB.MA0318-112RR. Epub 2018 Oct 4.

PMID:
30368901
7.

Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.

Zhong FL, Robinson K, Teo DET, Tan KY, Lim C, Harapas CR, Yu CH, Xie WH, Sobota RM, Au VB, Hopkins R, D'Osualdo A, Reed JC, Connolly JE, Masters SL, Reversade B.

J Biol Chem. 2018 Dec 7;293(49):18864-18878. doi: 10.1074/jbc.RA118.004350. Epub 2018 Oct 5.

PMID:
30291141
8.

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.

Tye H, Yu CH, Simms LA, de Zoete MR, Kim ML, Zakrzewski M, Penington JS, Harapas CR, Souza-Fonseca-Guimaraes F, Wockner LF, Preaudet A, Mielke LA, Wilcox SA, Ogura Y, Corr SC, Kanojia K, Kouremenos KA, De Souza DP, McConville MJ, Flavell RA, Gerlic M, Kile BT, Papenfuss AT, Putoczki TL, Radford-Smith GL, Masters SL.

Nat Commun. 2018 Sep 13;9(1):3728. doi: 10.1038/s41467-018-06125-0.

9.

Ximmer: a system for improving accuracy and consistency of CNV calling from exome data.

Sadedin SP, Ellis JA, Masters SL, Oshlack A.

Gigascience. 2018 Oct 1;7(10). doi: 10.1093/gigascience/giy112.

10.

The classification, genetic diagnosis and modelling of monogenic autoinflammatory disorders.

Moghaddas F, Masters SL.

Clin Sci (Lond). 2018 Sep 5;132(17):1901-1924. doi: 10.1042/CS20171498. Print 2018 Sep 14. Review.

11.

Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling.

De Nardo D, Balka KR, Cardona Gloria Y, Rao VR, Latz E, Masters SL.

J Biol Chem. 2018 Sep 28;293(39):15195-15207. doi: 10.1074/jbc.RA118.003314. Epub 2018 Aug 3.

12.

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy.

Saldanha RG, Balka KR, Davidson S, Wainstein BK, Wong M, Macintosh R, Loo CKC, Weber MA, Kamath V; CIRCA; AADRY, Moghaddas F, De Nardo D, Gray PE, Masters SL.

Front Immunol. 2018 Jul 6;9:1535. doi: 10.3389/fimmu.2018.01535. eCollection 2018.

13.

Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes.

Bitto NJ, Baker PJ, Dowling JK, Wray-McCann G, De Paoli A, Tran LS, Leung PL, Stacey KJ, Mansell A, Masters SL, Ferrero RL.

Immunol Cell Biol. 2018 Nov;96(10):1120-1130. doi: 10.1111/imcb.12190. Epub 2018 Aug 14.

PMID:
30003588
14.

An Update on Autoinflammatory Diseases: Relopathies.

Steiner A, Harapas CR, Masters SL, Davidson S.

Curr Rheumatol Rep. 2018 May 30;20(7):39. doi: 10.1007/s11926-018-0749-x. Review.

PMID:
29846841
15.

An Update on Autoinflammatory Diseases: Inflammasomopathies.

Harapas CR, Steiner A, Davidson S, Masters SL.

Curr Rheumatol Rep. 2018 May 30;20(7):40. doi: 10.1007/s11926-018-0750-4. Review.

PMID:
29846819
16.

An Update on Autoinflammatory Diseases: Interferonopathies.

Davidson S, Steiner A, Harapas CR, Masters SL.

Curr Rheumatol Rep. 2018 May 30;20(7):38. doi: 10.1007/s11926-018-0748-y. Review.

PMID:
29846818
17.

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.

Moghaddas F, Zeng P, Zhang Y, Schützle H, Brenner S, Hofmann SR, Berner R, Zhao Y, Lu B, Chen X, Zhang L, Cheng S, Winkler S, Lehmberg K, Canna SW, Czabotar PE, Wicks IP, De Nardo D, Hedrich CM, Zeng H, Masters SL.

J Allergy Clin Immunol. 2018 Dec;142(6):1956-1967.e6. doi: 10.1016/j.jaci.2018.04.033. Epub 2018 May 17.

18.

Caspase substrates won't be defined by a four-letter code.

Baker PJ, Masters SL.

J Biol Chem. 2018 May 4;293(18):7068-7069. doi: 10.1074/jbc.H118.002802.

19.

The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection.

Alhallaf R, Agha Z, Miller CM, Robertson AAB, Sotillo J, Croese J, Cooper MA, Masters SL, Kupz A, Smith NC, Loukas A, Giacomin PR.

Cell Rep. 2018 Apr 24;23(4):1085-1098. doi: 10.1016/j.celrep.2018.03.097.

20.

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

Lancaster GI, Langley KG, Berglund NA, Kammoun HL, Reibe S, Estevez E, Weir J, Mellett NA, Pernes G, Conway JRW, Lee MKS, Timpson P, Murphy AJ, Masters SL, Gerondakis S, Bartonicek N, Kaczorowski DC, Dinger ME, Meikle PJ, Bond PJ, Febbraio MA.

Cell Metab. 2018 May 1;27(5):1096-1110.e5. doi: 10.1016/j.cmet.2018.03.014. Epub 2018 Apr 19.

21.

Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment.

Nakamura K, Kassem S, Cleynen A, Chrétien ML, Guillerey C, Putz EM, Bald T, Förster I, Vuckovic S, Hill GR, Masters SL, Chesi M, Bergsagel PL, Avet-Loiseau H, Martinet L, Smyth MJ.

Cancer Cell. 2018 Apr 9;33(4):634-648.e5. doi: 10.1016/j.ccell.2018.02.007.

22.

Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury.

Mitra S, Exline M, Habyarimana F, Gavrilin MA, Baker PJ, Masters SL, Wewers MD, Sarkar A.

Am J Respir Cell Mol Biol. 2018 Jul;59(1):56-64. doi: 10.1165/rcmb.2017-0393OC.

23.

Identification of a second binding site on the TRIM25 B30.2 domain.

D'Cruz AA, Kershaw NJ, Hayman TJ, Linossi EM, Chiang JJ, Wang MK, Dagley LF, Kolesnik TB, Zhang JG, Masters SL, Griffin MDW, Gack MU, Murphy JM, Nicola NA, Babon JJ, Nicholson SE.

Biochem J. 2018 Jan 23;475(2):429-440. doi: 10.1042/BCJ20170427.

24.

Generation of Genetic Knockouts in Myeloid Cell Lines Using a Lentiviral CRISPR/Cas9 System.

Baker PJ, Masters SL.

Methods Mol Biol. 2018;1714:41-55. doi: 10.1007/978-1-4939-7519-8_3.

PMID:
29177854
25.

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.

Nguyen TA, Smith BRC, Tate MD, Belz GT, Barrios MH, Elgass KD, Weisman AS, Baker PJ, Preston SP, Whitehead L, Garnham A, Lundie RJ, Smyth GK, Pellegrini M, O'Keeffe M, Wicks IP, Masters SL, Hunter CP, Pang KC.

Immunity. 2017 Sep 19;47(3):498-509.e6. doi: 10.1016/j.immuni.2017.08.007. Epub 2017 Sep 12.

26.

Embracing chemical and structural diversity with UCONGA: A universal conformer generation and analysis program.

Gunby NR, Masters SL, Crittenden DL.

J Mol Graph Model. 2017 Oct;77:286-294. doi: 10.1016/j.jmgm.2017.09.007. Epub 2017 Sep 6.

PMID:
28915446
27.

A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.

Moghaddas F, Llamas R, De Nardo D, Martinez-Banaclocha H, Martinez-Garcia JJ, Mesa-Del-Castillo P, Baker PJ, Gargallo V, Mensa-Vilaro A, Canna S, Wicks IP, Pelegrin P, Arostegui JI, Masters SL.

Ann Rheum Dis. 2017 Dec;76(12):2085-2094. doi: 10.1136/annrheumdis-2017-211473. Epub 2017 Aug 23.

28.

Mechanisms of NLRP1-Mediated Autoinflammatory Disease in Humans and Mice.

Yu CH, Moecking J, Geyer M, Masters SL.

J Mol Biol. 2018 Jan 19;430(2):142-152. doi: 10.1016/j.jmb.2017.07.012. Epub 2017 Jul 19. Review.

PMID:
28733143
29.

A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization.

Hutton ML, D'Costa K, Rossiter AE, Wang L, Turner L, Steer DL, Masters SL, Croker BA, Kaparakis-Liaskos M, Ferrero RL.

Front Cell Infect Microbiol. 2017 Jun 6;7:219. doi: 10.3389/fcimb.2017.00219. eCollection 2017.

30.

Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.

Baker PJ, De Nardo D, Moghaddas F, Tran LS, Bachem A, Nguyen T, Hayman T, Tye H, Vince JE, Bedoui S, Ferrero RL, Masters SL.

Physiol Rev. 2017 Jul 1;97(3):1165-1209. doi: 10.1152/physrev.00026.2016. Review.

31.

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson JC, Tye H, Biette K, Jedlicka P, Brodsky KS, Gerich ME, Mack M, Robertson AAB, Cooper MA, Furuta GT, Dinarello CA, O'Neill LA, Eltzschig HK, Masters SL, McNamee EN.

J Exp Med. 2017 Jun 5;214(6):1737-1752. doi: 10.1084/jem.20160462. Epub 2017 May 9.

32.

The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome.

Haneklaus M, O'Neil JD, Clark AR, Masters SL, O'Neill LAJ.

J Biol Chem. 2017 Apr 28;292(17):6869-6881. doi: 10.1074/jbc.M116.772947. Epub 2017 Mar 16.

33.

Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin.

Speir M, Vogrin A, Seidi A, Abraham G, Hunot S, Han Q, Dorn GW 2nd, Masters SL, Flavell RA, Vince JE, Naderer T.

Front Cell Infect Microbiol. 2017 Feb 16;7:35. doi: 10.3389/fcimb.2017.00035. eCollection 2017.

34.

Erratum: EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.

Pearson JS, Giogha C, Mühlen S, Nachbur U, Pham CL, Zhang Y, Hildebrand JM, Oates CV, Lung TW, Ingle D, Dagley LF, Bankovacki A, Petrie EJ, Schroeder GN, Crepin VF, Frankel G, Masters SL, Vince J, Murphy JM, Sunde M, Webb AI, Silke J, Hartland EL.

Nat Microbiol. 2017 Feb 13;2:17024. doi: 10.1038/nmicrobiol.2017.24. No abstract available.

35.

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.

Mridha AR, Wree A, Robertson AAB, Yeh MM, Johnson CD, Van Rooyen DM, Haczeyni F, Teoh NC, Savard C, Ioannou GN, Masters SL, Schroder K, Cooper MA, Feldstein AE, Farrell GC.

J Hepatol. 2017 May;66(5):1037-1046. doi: 10.1016/j.jhep.2017.01.022. Epub 2017 Feb 3.

36.

Homeostasis-altering molecular processes as mechanisms of inflammasome activation.

Liston A, Masters SL.

Nat Rev Immunol. 2017 Mar;17(3):208-214. doi: 10.1038/nri.2016.151. Epub 2017 Feb 6. Review.

PMID:
28163301
37.

Inflammasome Priming in Sterile Inflammatory Disease.

Patel MN, Carroll RG, Galván-Peña S, Mills EL, Olden R, Triantafilou M, Wolf AI, Bryant CE, Triantafilou K, Masters SL.

Trends Mol Med. 2017 Feb;23(2):165-180. doi: 10.1016/j.molmed.2016.12.007. Epub 2017 Jan 18. Review.

PMID:
28109721
38.

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

Conos SA, Chen KW, De Nardo D, Hara H, Whitehead L, Núñez G, Masters SL, Murphy JM, Schroder K, Vaux DL, Lawlor KE, Lindqvist LM, Vince JE.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969. doi: 10.1073/pnas.1613305114. Epub 2017 Jan 17. Erratum in: Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5762-E5763.

39.

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.

Pearson JS, Giogha C, Mühlen S, Nachbur U, Pham CL, Zhang Y, Hildebrand JM, Oates CV, Lung TW, Ingle D, Dagley LF, Bankovacki A, Petrie EJ, Schroeder GN, Crepin VF, Frankel G, Masters SL, Vince J, Murphy JM, Sunde M, Webb AI, Silke J, Hartland EL.

Nat Microbiol. 2017 Jan 13;2:16258. doi: 10.1038/nmicrobiol.2016.258. Erratum in: Nat Microbiol. 2017 Feb 13;2:17024.

40.

Intercellular communication for innate immunity.

Nguyen TA, Pang KC, Masters SL.

Mol Immunol. 2017 Jun;86:16-22. doi: 10.1016/j.molimm.2016.10.002. Epub 2016 Oct 18. Review.

PMID:
27769523
41.

The modern interleukin-1 superfamily: Divergent roles in obesity.

Lee MK, Yvan-Charvet L, Masters SL, Murphy AJ.

Semin Immunol. 2016 Oct;28(5):441-449. doi: 10.1016/j.smim.2016.10.001. Epub 2016 Oct 7. Review.

PMID:
27726910
42.

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation.

Zhong FL, Mamaï O, Sborgi L, Boussofara L, Hopkins R, Robinson K, Szeverényi I, Takeichi T, Balaji R, Lau A, Tye H, Roy K, Bonnard C, Ahl PJ, Jones LA, Baker PJ, Lacina L, Otsuka A, Fournie PR, Malecaze F, Lane EB, Akiyama M, Kabashima K, Connolly JE, Masters SL, Soler VJ, Omar SS, McGrath JA, Nedelcu R, Gribaa M, Denguezli M, Saad A, Hiller S, Reversade B.

Cell. 2016 Sep 22;167(1):187-202.e17. doi: 10.1016/j.cell.2016.09.001.

43.

Granzyme M has a critical role in providing innate immune protection in ulcerative colitis.

Souza-Fonseca-Guimaraes F, Krasnova Y, Putoczki T, Miles K, MacDonald KP, Town L, Shi W, Gobe GC, McDade L, Mielke LA, Tye H, Masters SL, Belz GT, Huntington ND, Radford-Smith G, Smyth MJ.

Cell Death Dis. 2016 Jul 21;7:e2302. doi: 10.1038/cddis.2016.215.

44.

Avenues to autoimmune arthritis triggered by diverse remote inflammatory challenges.

Chevalier N, Tan JK, Mason LJ, Robert R, McKenzie CI, Lim F, Wong CH, Macia L, Thorburn AN, Russ BE, Masters SL, Mackay CR.

J Autoimmun. 2016 Sep;73:120-9. doi: 10.1016/j.jaut.2016.06.018. Epub 2016 Jul 12.

PMID:
27427404
45.

The efficacy of behavioural activation treatment for co-occurring depression and substance use disorder (the activate study): a randomized controlled trial.

Ross J, Teesson M, Lejuez C, Mills K, Kaye S, Brady K, Dore G, Prior K, Larkin X, Cassar J, Ewer P, Memedovic S, Kihas I, Masters SL.

BMC Psychiatry. 2016 Jul 8;16:221. doi: 10.1186/s12888-016-0943-1.

46.

Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan.

Zhan Y, Chow KV, Soo P, Xu Z, Brady JL, Lawlor KE, Masters SL, O'keeffe M, Shortman K, Zhang JG, Lew AM.

Sci Rep. 2016 Apr 26;6:25060. doi: 10.1038/srep25060.

47.

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.

Masters SL, Lagou V, Jéru I, Baker PJ, Van Eyck L, Parry DA, Lawless D, De Nardo D, Garcia-Perez JE, Dagley LF, Holley CL, Dooley J, Moghaddas F, Pasciuto E, Jeandel PY, Sciot R, Lyras D, Webb AI, Nicholson SE, De Somer L, van Nieuwenhove E, Ruuth-Praz J, Copin B, Cochet E, Medlej-Hashim M, Megarbane A, Schroder K, Savic S, Goris A, Amselem S, Wouters C, Liston A.

Sci Transl Med. 2016 Mar 30;8(332):332ra45. doi: 10.1126/scitranslmed.aaf1471.

48.

Gas-Phase Structures of Ketene and Acetic Acid from Acetic Anhydride Using Very-High-Temperature Gas Electron Diffraction.

Atkinson SJ, Noble-Eddy R, Masters SL.

J Phys Chem A. 2016 Mar 31;120(12):2041-8. doi: 10.1021/acs.jpca.6b00704. Epub 2016 Mar 22.

PMID:
26916368
49.

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.

Uboldi AD, McCoy JM, Blume M, Gerlic M, Ferguson DJ, Dagley LF, Beahan CT, Stapleton DI, Gooley PR, Bacic A, Masters SL, Webb AI, McConville MJ, Tonkin CJ.

Cell Host Microbe. 2015 Dec 9;18(6):670-81. doi: 10.1016/j.chom.2015.11.004.

50.

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

Murphy AJ, Kraakman MJ, Kammoun HL, Dragoljevic D, Lee MK, Lawlor KE, Wentworth JM, Vasanthakumar A, Gerlic M, Whitehead LW, DiRago L, Cengia L, Lane RM, Metcalf D, Vince JE, Harrison LC, Kallies A, Kile BT, Croker BA, Febbraio MA, Masters SL.

Cell Metab. 2016 Jan 12;23(1):155-64. doi: 10.1016/j.cmet.2015.09.024. Epub 2015 Oct 22.

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