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Items: 29

1.

SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.

Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, Belli R, Taverna S, Andreazzoli M, Zippo A, Broccoli V.

Neuron. 2019 Sep 9. pii: S0896-6273(19)30639-7. doi: 10.1016/j.neuron.2019.07.013. [Epub ahead of print]

PMID:
31515109
2.

mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn's Disease.

Ungaro F, Garlatti V, Massimino L, Spinelli A, Carvello M, Sacchi M, Spanò S, Colasante G, Valassina N, Vetrano S, Malesci A, Peyrin-Biroulet L, Danese S, D'Alessio S.

Cells. 2019 Aug 18;8(8). pii: E924. doi: 10.3390/cells8080924.

3.

Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer.

Tacconi C, Ungaro F, Correale C, Arena V, Massimino L, Detmar M, Spinelli A, Carvello M, Mazzone M, Oliveira AI, Rubbino F, Garlatti V, Spanò S, Lugli E, Colombo FS, Malesci A, Peyrin-Biroulet L, Vetrano S, Danese S, D'Alessio S.

Cancer Res. 2019 Aug 15;79(16):4196-4210. doi: 10.1158/0008-5472.CAN-18-3657. Epub 2019 Jun 25.

PMID:
31239267
4.

In Vivo Comparative Study on Acute and Sub-acute Biological Effects Induced by Ultrafine Particles of Different Anthropogenic Sources in BALB/c Mice.

Farina F, Lonati E, Milani C, Massimino L, Ballarini E, Donzelli E, Crippa L, Marmiroli P, Botto L, Corsetto PA, Sancini G, Bulbarelli A, Palestini P.

Int J Mol Sci. 2019 Jun 8;20(11). pii: E2805. doi: 10.3390/ijms20112805.

5.

Direct Neuronal Reprogramming Reveals Unknown Functions for Known Transcription Factors.

Colasante G, Rubio A, Massimino L, Broccoli V.

Front Neurosci. 2019 Mar 26;13:283. doi: 10.3389/fnins.2019.00283. eCollection 2019. Review.

6.

TNF-Stimulated Gene-6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells.

Romano B, Elangovan S, Erreni M, Sala E, Petti L, Kunderfranco P, Massimino L, Restelli S, Sinha S, Lucchetti D, Anselmo A, Colombo FS, Stravalaci M, Arena V, D'Alessio S, Ungaro F, Inforzato A, Izzo AA, Sgambato A, Day AJ, Vetrano S.

Stem Cells. 2019 Jul;37(7):973-987. doi: 10.1002/stem.3010. Epub 2019 May 14.

PMID:
30942926
7.

Lymphatic endothelium contributes to colorectal cancer growth via the soluble matrisome component GDF11.

Ungaro F, Colombo P, Massimino L, Ugolini GS, Correale C, Rasponi M, Garlatti V, Rubbino F, Tacconi C, Spaggiari P, Spinelli A, Carvello M, Sacchi M, Spanò S, Vetrano S, Malesci A, Peyrin-Biroulet L, Danese S, D'Alessio S.

Int J Cancer. 2019 Oct 1;145(7):1913-1920. doi: 10.1002/ijc.32286. Epub 2019 Apr 9.

PMID:
30889293
8.

De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways.

Magistroni V, Mauri M, D'Aliberti D, Mezzatesta C, Crespiatico I, Nava M, Fontana D, Sharma N, Parker W, Schreiber A, Yeung D, Pirola A, Readelli S, Massimino L, Wang P, Khandelwal P, Citterio S, Viltadi M, Bombelli S, Rigolio R, Perego R, Boultwood J, Morotti A, Saglio G, Kim DW, Branford S, Gambacorti-Passerini C, Piazza R.

Haematologica. 2019 Sep;104(9):1789-1797. doi: 10.3324/haematol.2017.179937. Epub 2019 Feb 28.

9.

Mitochondrial Hyperactivation and Enhanced ROS Production are Involved in Toxicity Induced by Oncogenic Kinases Over-Signaling.

Ceccon M, Mauri M, Massimino L, Giudici G, Piazza R, Gambacorti-Passerini C, Mologni L.

Cancers (Basel). 2018 Dec 12;10(12). pii: E509. doi: 10.3390/cancers10120509.

10.

Lorlatinib Treatment Elicits Multiple On- and Off-Target Mechanisms of Resistance in ALK-Driven Cancer.

Redaelli S, Ceccon M, Zappa M, Sharma GG, Mastini C, Mauri M, Nigoghossian M, Massimino L, Cordani N, Farina F, Piazza R, Gambacorti-Passerini C, Mologni L.

Cancer Res. 2018 Dec 15;78(24):6866-6880. doi: 10.1158/0008-5472.CAN-18-1867. Epub 2018 Oct 15.

PMID:
30322862
11.

Metagenomic analysis of intestinal mucosa revealed a specific eukaryotic gut virome signature in early-diagnosed inflammatory bowel disease.

Ungaro F, Massimino L, Furfaro F, Rimoldi V, Peyrin-Biroulet L, D'Alessio S, Danese S.

Gut Microbes. 2019;10(2):149-158. doi: 10.1080/19490976.2018.1511664. Epub 2018 Sep 25.

PMID:
30252582
12.

Early evidence of stress in immortalized neurons exposed to diesel particles: the role of lipid reshaping behind oxidative stress and inflammation.

Milani C, Corsetto PA, Farina F, Botto L, Lonati E, Massimino L, Rizzo AM, Bulbarelli A, Palestini P.

Toxicology. 2018 Nov 1;409:63-72. doi: 10.1016/j.tox.2018.07.017. Epub 2018 Jul 25.

PMID:
30055298
13.

SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub.

Piazza R, Magistroni V, Redaelli S, Mauri M, Massimino L, Sessa A, Peronaci M, Lalowski M, Soliymani R, Mezzatesta C, Pirola A, Banfi F, Rubio A, Rea D, Stagno F, Usala E, Martino B, Campiotti L, Merli M, Passamonti F, Onida F, Morotti A, Pavesi F, Bregni M, Broccoli V, Baumann M, Gambacorti-Passerini C.

Nat Commun. 2018 Jun 6;9(1):2192. doi: 10.1038/s41467-018-04462-8.

14.

Concomitant BCORL1 and BRAF Mutations in Vemurafenib-Resistant Melanoma Cells.

Mologni L, Costanza M, Sharma GG, Viltadi M, Massimino L, Citterio S, Purgante S, Raman H, Pirola A, Zucchetti M, Piazza R, Gambacorti-Passerini C.

Neoplasia. 2018 May;20(5):467-477. doi: 10.1016/j.neo.2018.02.009. Epub 2018 Mar 30.

15.

Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models.

Iannielli A, Bido S, Folladori L, Segnali A, Cancellieri C, Maresca A, Massimino L, Rubio A, Morabito G, Caporali L, Tagliavini F, Musumeci O, Gregato G, Bezard E, Carelli V, Tiranti V, Broccoli V.

Cell Rep. 2018 Feb 20;22(8):2066-2079. doi: 10.1016/j.celrep.2018.01.089.

16.

TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis.

Massimino L, Flores-Garcia L, Di Stefano B, Colasante G, Icoresi-Mazzeo C, Zaghi M, Hamilton BA, Sessa A.

Dev Biol. 2018 Feb 15;434(2):231-248. doi: 10.1016/j.ydbio.2017.12.020. Epub 2018 Jan 2.

17.

Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery.

Giannelli SG, Luoni M, Castoldi V, Massimino L, Cabassi T, Angeloni D, Demontis GC, Leocani L, Andreazzoli M, Broccoli V.

Hum Mol Genet. 2018 Mar 1;27(5):761-779. doi: 10.1093/hmg/ddx438.

PMID:
29281027
18.

The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.

Sessa A, Ciabatti E, Drechsel D, Massimino L, Colasante G, Giannelli S, Satoh T, Akira S, Guillemot F, Broccoli V.

Cereb Cortex. 2017 Dec 1;27(12):5715. doi: 10.1093/cercor/bhx209. No abstract available.

PMID:
28968796
19.

MFSD2A Promotes Endothelial Generation of Inflammation-Resolving Lipid Mediators and Reduces Colitis in Mice.

Ungaro F, Tacconi C, Massimino L, Corsetto PA, Correale C, Fonteyne P, Piontini A, Garzarelli V, Calcaterra F, Della Bella S, Spinelli A, Carvello M, Rizzo AM, Vetrano S, Petti L, Fiorino G, Furfaro F, Mavilio D, Maddipati KR, Malesci A, Peyrin-Biroulet L, D'Alessio S, Danese S.

Gastroenterology. 2017 Nov;153(5):1363-1377.e6. doi: 10.1053/j.gastro.2017.07.048. Epub 2017 Aug 4.

20.

In silico discovery of terpenoid metabolism in Cannabis sativa.

Massimino L.

F1000Res. 2017 Feb 6;6:107. doi: 10.12688/f1000research.10778.1. eCollection 2017.

21.

In silico gene expression profiling in Cannabis sativa.

Massimino L.

F1000Res. 2017 Jan 23;6:69. doi: 10.12688/f1000research.10631.1. eCollection 2017.

22.

Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells.

Mazzara PG, Massimino L, Pellegatta M, Ronchi G, Ricca A, Iannielli A, Giannelli SG, Cursi M, Cancellieri C, Sessa A, Del Carro U, Quattrini A, Geuna S, Gritti A, Taveggia C, Broccoli V.

Nat Commun. 2017 Feb 7;8:14088. doi: 10.1038/ncomms14088.

23.

The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.

Sessa A, Ciabatti E, Drechsel D, Massimino L, Colasante G, Giannelli S, Satoh T, Akira S, Guillemot F, Broccoli V.

Cereb Cortex. 2017 Jun 1;27(6):3378-3396. doi: 10.1093/cercor/bhw270. Erratum in: Cereb Cortex. 2017 Dec 1;27(12):5715.

PMID:
27600842
24.

Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming.

Colasante G, Lignani G, Rubio A, Medrihan L, Yekhlef L, Sessa A, Massimino L, Giannelli SG, Sacchetti S, Caiazzo M, Leo D, Alexopoulou D, Dell'Anno MT, Ciabatti E, Orlando M, Studer M, Dahl A, Gainetdinov RR, Taverna S, Benfenati F, Broccoli V.

Cell Stem Cell. 2015 Dec 3;17(6):719-734. doi: 10.1016/j.stem.2015.09.002. Epub 2015 Oct 29.

25.

Altered expression of neuropeptides in FoxG1-null heterozygous mutant mice.

Frullanti E, Amabile S, Lolli MG, Bartolini A, Livide G, Landucci E, Mari F, Vaccarino FM, Ariani F, Massimino L, Renieri A, Meloni I.

Eur J Hum Genet. 2016 Feb;24(2):252-7. doi: 10.1038/ejhg.2015.79. Epub 2015 May 13.

26.

Direct conversion of fibroblasts into functional astrocytes by defined transcription factors.

Caiazzo M, Giannelli S, Valente P, Lignani G, Carissimo A, Sessa A, Colasante G, Bartolomeo R, Massimino L, Ferroni S, Settembre C, Benfenati F, Broccoli V.

Stem Cell Reports. 2015 Jan 13;4(1):25-36. doi: 10.1016/j.stemcr.2014.12.002. Epub 2014 Dec 31.

27.

Recombinant disintegrin targets α(v) β(3) integrin and leads to mediator production.

Ribeiro LC, Massimino LC, Durante AC, Tansini A, Urbaczek AC, Selistre-de-Araújo HS, Carlos IZ.

Cell Adh Migr. 2014;8(1):60-5. doi: 10.4161/cam.27698. Epub 2013 Jan 1.

28.

Donepezil is ineffective in promoting motor and cognitive benefits after controlled cortical impact injury in male rats.

Shaw KE, Bondi CO, Light SH, Massimino LA, McAloon RL, Monaco CM, Kline AE.

J Neurotrauma. 2013 Apr 1;30(7):557-64. doi: 10.1089/neu.2012.2782. Epub 2013 Mar 26.

29.

Local insulin-like growth factor I expression is essential for Purkinje neuron survival at birth.

Croci L, Barili V, Chia D, Massimino L, van Vugt R, Masserdotti G, Longhi R, Rotwein P, Consalez GG.

Cell Death Differ. 2011 Jan;18(1):48-59. doi: 10.1038/cdd.2010.78. Epub 2010 Jul 2.

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