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Long-lasting microbial dysbiosis and altered enteric neurotransmitters in adult rats following adolescent binge ethanol exposure.

Vetreno RP, Massey V, Crews FT.

Addict Biol. 2019 Dec 27:e12869. doi: 10.1111/adb.12869. [Epub ahead of print]


Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R.

Nat Commun. 2019 Jul 16;10(1):3126. doi: 10.1038/s41467-019-11004-3.


TLR7-let-7 Signaling Contributes to Ethanol-Induced Hepatic Inflammatory Response in Mice and in Alcoholic Hepatitis.

Massey VL, Qin L, Cabezas J, Caballeria J, Sancho-Bru P, Bataller R, Crews FT.

Alcohol Clin Exp Res. 2018 Nov;42(11):2107-2122. doi: 10.1111/acer.13871. Epub 2018 Sep 10.


β-Hydroxybutyrate protects from alcohol-induced liver injury via a Hcar2-cAMP dependent pathway.

Chen Y, Ouyang X, Hoque R, Garcia-Martinez I, Yousaf MN, Tonack S, Offermanns S, Dubuquoy L, Louvet A, Mathurin P, Massey V, Schnabl B, Bataller RA, Mehal WZ.

J Hepatol. 2018 Sep;69(3):687-696. doi: 10.1016/j.jhep.2018.04.004. Epub 2018 Apr 27.


Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins.

Hudson SV, Dolin CE, Poole LG, Massey VL, Wilkey D, Beier JI, Merchant ML, Frieboes HB, Arteel GE.

Sci Rep. 2017 Sep 29;7(1):12444. doi: 10.1038/s41598-017-12691-y.


Epigenetics in Liver Fibrosis.

Massey V, Cabezas J, Bataller R.

Semin Liver Dis. 2017 Aug;37(3):219-230. doi: 10.1055/s-0037-1605371. Epub 2017 Aug 28. Review. No abstract available.


Plasminogen Activator Inhibitor-1 Is Critical in Alcohol-Enhanced Acute Lung Injury in Mice.

Poole LG, Massey VL, Siow DL, Torres-Gonzáles E, Warner NL, Luyendyk JP, Ritzenthaler JD, Roman J, Arteel GE.

Am J Respir Cell Mol Biol. 2017 Sep;57(3):315-323. doi: 10.1165/rcmb.2016-0184OC.


The hepatic "matrisome" responds dynamically to injury: Characterization of transitional changes to the extracellular matrix in mice.

Massey VL, Dolin CE, Poole LG, Hudson SV, Siow DL, Brock GN, Merchant ML, Wilkey DW, Arteel GE.

Hepatology. 2017 Mar;65(3):969-982. doi: 10.1002/hep.28918. Epub 2016 Dec 30.


Potential Role of the Gut/Liver/Lung Axis in Alcohol-Induced Tissue Pathology.

Massey VL, Beier JI, Ritzenthaler JD, Roman J, Arteel GE.

Biomolecules. 2015 Sep 30;5(4):2477-503. doi: 10.3390/biom5042477. Review.


Chronic Alcohol Exposure Enhances Lipopolysaccharide-Induced Lung Injury in Mice: Potential Role of Systemic Tumor Necrosis Factor-Alpha.

Massey VL, Poole LG, Siow DL, Torres E, Warner NL, Schmidt RH, Ritzenthaler JD, Roman J, Arteel GE.

Alcohol Clin Exp Res. 2015 Oct;39(10):1978-88. doi: 10.1111/acer.12855. Epub 2015 Sep 18.


Oligofructose protects against arsenic-induced liver injury in a model of environment/obesity interaction.

Massey VL, Stocke KS, Schmidt RH, Tan M, Ajami N, Neal RE, Petrosino JF, Barve S, Arteel GE.

Toxicol Appl Pharmacol. 2015 May 1;284(3):304-14. doi: 10.1016/j.taap.2015.02.022. Epub 2015 Mar 8.


Neuropsychological Impairments and Age-Related Differences in Children and Adolescents with Fetal Alcohol Spectrum Disorders.

Tamana S, Pei J, Massey D, Massey V, Rasmussen C.

J Popul Ther Clin Pharmacol. 2014;21(2):e167-80. Epub 2014 May 10.


Olanzapine activates hepatic mammalian target of rapamycin: new mechanistic insight into metabolic dysregulation with atypical antipsychotic drugs.

Schmidt RH, Jokinen JD, Massey VL, Falkner KC, Shi X, Yin X, Zhang X, Beier JI, Arteel GE.

J Pharmacol Exp Ther. 2013 Oct;347(1):126-35. doi: 10.1124/jpet.113.207621. Epub 2013 Aug 7.


Acute alcohol-induced liver injury.

Massey VL, Arteel GE.

Front Physiol. 2012 Jun 12;3:193. doi: 10.3389/fphys.2012.00193. eCollection 2012.


BEACOPP chemotherapy is a highly effective regimen in children and adolescents with high-risk Hodgkin lymphoma: a report from the Children's Oncology Group.

Kelly KM, Sposto R, Hutchinson R, Massey V, McCarten K, Perkins S, Lones M, Villaluna D, Weiner M.

Blood. 2011 Mar 3;117(9):2596-603. doi: 10.1182/blood-2010-05-285379. Epub 2010 Nov 15.


Future of health care sobers many at AMA interim meeting.

Gale A, Huffaker W, Massey V, Murdock N, Murrell J, Redfern D, Ryall JE.

Mo Med. 2009 Jan-Feb;106(1):23-4. No abstract available.


Relationship between smoking status and body weight in a military population of young adults.

Sherrill-Mittleman D, Klesges RC, Massey V, Vander Weg MW, DeBon M.

Addict Behav. 2009 Apr;34(4):400-2. doi: 10.1016/j.addbeh.2008.11.015. Epub 2008 Nov 24. Review.


Memory patterns of acquisition and retention of verbal and nonverbal information in children with fetal alcohol spectrum disorders.

Pei JR, Rinaldi CM, Rasmussen C, Massey V, Massey D.

Can J Clin Pharmacol. 2008 Winter;15(1):e44-56. Epub 2008 Jan 9.


Conformational dynamics of the isoalloxazine in substrate-free p-hydroxybenzoate hydroxylase: single-molecule studies.

Brender JR, Dertouzos J, Ballou DP, Massey V, Palfey BA, Entsch B, Steel DG, Gafni A.

J Am Chem Soc. 2005 Dec 28;127(51):18171-8.


Use of 8-substituted-FAD analogues to investigate the hydroxylation mechanism of the flavoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase.

Chaiyen P, Sucharitakul J, Svasti J, Entsch B, Massey V, Ballou DP.

Biochemistry. 2004 Apr 6;43(13):3933-43.


Streptococcus equi subspecies equi (Lancefield group C) meningitis in a child.

Elsayed S, Hammerberg O, Massey V, Hussain Z.

Clin Microbiol Infect. 2003 Aug;9(8):869-72.


The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster.

Bauer H, Massey V, Arscott LD, Schirmer RH, Ballou DP, Williams CH Jr.

J Biol Chem. 2003 Aug 29;278(35):33020-8. Epub 2003 Jun 19.


Altered balance of half-reactions in p-hydroxybenzoate hydroxylase caused by substituting the 2'-carbon of FAD with fluorine.

Palfey BA, Murthy YV, Massey V.

J Biol Chem. 2003 Jun 20;278(25):22210-6. Epub 2003 Apr 8.


Studies of the mechanism of phenol hydroxylase: effect of mutation of proline 364 to serine.

Xu D, Enroth C, Lindqvist Y, Ballou DP, Massey V.

Biochemistry. 2002 Nov 19;41(46):13627-36.


Reaction of reduced flavins and flavoproteins with diphenyliodonium chloride.

Chakraborty S, Massey V.

J Biol Chem. 2002 Nov 1;277(44):41507-16. Epub 2002 Aug 16.


Preradiation chemotherapy in primary high-risk brainstem tumors: phase II study CCG-9941 of the Children's Cancer Group.

Jennings MT, Sposto R, Boyett JM, Vezina LG, Holmes E, Berger MS, Bruggers CS, Bruner JM, Chan KW, Dusenbery KE, Ettinger LJ, Fitz CR, Lafond D, Mandelbaum DE, Massey V, McGuire W, McNeely L, Moulton T, Pollack IF, Shen V.

J Clin Oncol. 2002 Aug 15;20(16):3431-7.


Feasibility of upfront dose-intensive chemotherapy in children with advanced-stage Hodgkin's lymphoma: preliminary results from the Children's Cancer Group Study CCG-59704.

Kelly KM, Hutchinson RJ, Sposto R, Weiner MA, Lones MA, Perkins SL, Massey V; Children's Oncology Group.

Ann Oncol. 2002;13 Suppl 1:107-11.


Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase.

Wang J, Ortiz-Maldonado M, Entsch B, Massey V, Ballou D, Gatti DL.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):608-13.


The role of glutamine 114 in old yellow enzyme.

Brown BJ, Hyun JW, Duvvuri S, Karplus PA, Massey V.

J Biol Chem. 2002 Jan 18;277(3):2138-45. Epub 2001 Oct 19.


An optomechanical transducer in the blue light receptor phototropin from Avena sativa.

Salomon M, Eisenreich W, Dürr H, Schleicher E, Knieb E, Massey V, Rüdiger W, Müller F, Bacher A, Richter G.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12357-61. Epub 2001 Oct 16.


Studies of the mechanism of phenol hydroxylase: mutants Tyr289Phe, Asp54Asn, and Arg281Met.

Xu D, Ballou DP, Massey V.

Biochemistry. 2001 Oct 16;40(41):12369-78.


Mechanistic studies of cyclohexanone monooxygenase: chemical properties of intermediates involved in catalysis.

Sheng D, Ballou DP, Massey V.

Biochemistry. 2001 Sep 18;40(37):11156-67.


Old yellow enzyme: reduction of nitrate esters, glycerin trinitrate, and propylene 1,2-dinitrate.

Meah Y, Brown BJ, Chakraborty S, Massey V.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8560-5. Epub 2001 Jul 3.


Hydrogen peroxide-forming NADH oxidase belonging to the peroxiredoxin oxidoreductase family: existence and physiological role in bacteria.

Nishiyama Y, Massey V, Takeda K, Kawasaki S, Sato J, Watanabe T, Niimura Y.

J Bacteriol. 2001 Apr;183(8):2431-8.


Evaluation of the Candigen enzyme-linked immunosorbent assay for quantitative detection of Candida species antigen.

Elsayed S, Fitzgerald V, Massey V, Hussain Z.

Arch Pathol Lab Med. 2001 Mar;125(3):344-6.


The thermodynamics of xanthine oxidoreductase catalysis.

Sanders SA, Massey V.

Antioxid Redox Signal. 1999 Fall;1(3):371-9. Review.


Interaction of two arginine residues in lactate oxidase with the enzyme flavin: conversion of FMN to 8-formyl-FMN.

Yorita K, Matsuoka T, Misaki H, Massey V.

Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13039-44.


The chemical and biological versatility of riboflavin.

Massey V.

Biochem Soc Trans. 2000;28(4):283-96. Review.


A hydrogen peroxide-forming NADH oxidase that functions as an alkyl hydroperoxide reductase in Amphibacillus xylanus.

Niimura Y, Nishiyama Y, Saito D, Tsuji H, Hidaka M, Miyaji T, Watanabe T, Massey V.

J Bacteriol. 2000 Sep;182(18):5046-51.


Design and properties of human D-amino acid oxidase with covalently attached flavin.

Raibekas AA, Fukui K, Massey V.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3089-93.


On the interpretation of quantitative structure-function activity relationship data for lactate oxidase.

Yorita K, Misaki H, Palfey BA, Massey V.

Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2480-5.


Thermodynamic properties of L-lactate oxidase reconstituted with modified flavins.

Aki K, Yorita K, Massey V.

Biofactors. 2000;11(1-2):115-6. No abstract available.


Correlation of oxacillin MIC with mecA gene carriage in coagulase-negative staphylococci.

Hussain Z, Stoakes L, Massey V, Diagre D, Fitzgerald V, El Sayed S, Lannigan R.

J Clin Microbiol. 2000 Feb;38(2):752-4.


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