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Items: 1 to 50 of 85

1.

Telomere length in the colon is related to colorectal adenoma prevalence.

Peacock SD, Massey TE, Vanner SJ, King WD.

PLoS One. 2018 Oct 17;13(10):e0205697. doi: 10.1371/journal.pone.0205697. eCollection 2018.

2.

Bulky DNA adduct levels in normal-appearing colon mucosa, and the prevalence of colorectal adenomas.

Ho V, Peacock S, Massey TE, Godschalk RW, van Schooten FJ, Ashbury JE, Vanner SJ, King WD.

Biomarkers. 2018 Dec;23(8):735-741. doi: 10.1080/1354750X.2018.1485055. Epub 2018 Jul 23.

PMID:
29871536
3.

Exposure to meat-derived carcinogens and bulky DNA adduct levels in normal-appearing colon mucosa.

Ho V, Brunetti V, Peacock S, Massey TE, Godschalk RWL, van Schooten FJ, Ashbury JE, Vanner SJ, King WD.

Mutat Res. 2017 Sep;821:5-12. doi: 10.1016/j.mrgentox.2017.06.005. Epub 2017 Jul 4.

PMID:
28735743
4.

The Influence of Alcohol Consumption, Cigarette Smoking, and Physical Activity on Leukocyte Telomere Length.

Latifovic L, Peacock SD, Massey TE, King WD.

Cancer Epidemiol Biomarkers Prev. 2016 Feb;25(2):374-80. doi: 10.1158/1055-9965.EPI-14-1364. Epub 2015 Dec 9.

5.

Gene-diet interactions in exposure to heterocyclic aromatic amines and bulky DNA adduct levels in blood leukocytes.

Ho V, Peacock S, Massey TE, Godschalk RW, van Schooten FJ, Chen J, King WD.

Environ Mol Mutagen. 2015 Aug;56(7):609-20. doi: 10.1002/em.21950. Epub 2015 May 22.

PMID:
26010176
6.

The impact of chronic Aflatoxin B1 exposure and p53 genotype on base excision repair in mouse lung and liver.

Mulder JE, Bondy GS, Mehta R, Massey TE.

Mutat Res. 2015 Mar;773:63-8. doi: 10.1016/j.mrfmmm.2015.01.015. Epub 2015 Jan 30.

PMID:
25847422
7.

Effect of 8-oxoguanine glycosylase deficiency on aflatoxin B1 tumourigenicity in mice.

Mulder JE, Turner PV, Massey TE.

Mutagenesis. 2015 May;30(3):401-9. doi: 10.1093/mutage/geu087. Epub 2015 Jan 11.

8.

Meat-derived carcinogens, genetic susceptibility and colorectal adenoma risk.

Ho V, Peacock S, Massey TE, Ashbury JE, Vanner SJ, King WD.

Genes Nutr. 2014 Nov;9(6):430. doi: 10.1007/s12263-014-0430-6. Epub 2014 Sep 18.

9.

In vivo treatment with aflatoxin B1 increases DNA oxidation, base excision repair activity and 8-oxoguanine DNA glycosylase 1 levels in mouse lung.

Guindon-Kezis KA, Mulder JE, Massey TE.

Toxicology. 2014 Jul 3;321:21-6. doi: 10.1016/j.tox.2014.03.004. Epub 2014 Mar 24.

PMID:
24675474
10.

Up-regulation of nucleotide excision repair in mouse lung and liver following chronic exposure to aflatoxin B₁ and its dependence on p53 genotype.

Mulder JE, Bondy GS, Mehta R, Massey TE.

Toxicol Appl Pharmacol. 2014 Mar 1;275(2):96-103. doi: 10.1016/j.taap.2013.12.016. Epub 2013 Dec 29.

PMID:
24380836
11.

Acute in vivo treatment with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone does not alter base excision repair activities in murine lung and liver.

Gupta N, Curtis RM, Mulder JE, Massey TE.

DNA Repair (Amst). 2013 Dec;12(12):1031-6. doi: 10.1016/j.dnarep.2013.09.009. Epub 2013 Oct 29.

PMID:
24182517
12.

Effects of methionine synthase and methylenetetrahydrofolate reductase gene polymorphisms on markers of one-carbon metabolism.

Ho V, Massey TE, King WD.

Genes Nutr. 2013 Nov;8(6):571-80. doi: 10.1007/s12263-013-0358-2. Epub 2013 Oct 8.

13.

Cytotoxic interaction between amiodarone and desethylamiodarone in human peripheral lung epithelial cells.

Roth FC, Mulder JE, Brien JF, Takahashi T, Massey TE.

Chem Biol Interact. 2013 Aug 25;204(3):135-9. doi: 10.1016/j.cbi.2013.05.006. Epub 2013 May 23.

PMID:
23707191
14.

Folate intake, alcohol consumption, and the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism: influence on prostate cancer risk and interactions.

Kobayashi LC, Limburg H, Miao Q, Woolcott C, Bedard LL, Massey TE, Aronson KJ.

Front Oncol. 2012 Aug 14;2:100. doi: 10.3389/fonc.2012.00100. eCollection 2012.

15.

Relationships among biomarkers of one-carbon metabolism.

King WD, Ho V, Dodds L, Perkins SL, Casson RI, Massey TE.

Mol Biol Rep. 2012 Jul;39(7):7805-12. doi: 10.1007/s11033-012-1623-y. Epub 2012 Apr 24.

PMID:
22528334
16.

Thymidylate synthase gene polymorphisms and markers of DNA methylation capacity.

Ho V, Massey TE, King WD.

Mol Genet Metab. 2011 Apr;102(4):481-7. doi: 10.1016/j.ymgme.2010.12.015. Epub 2010 Dec 31.

PMID:
21269855
17.

Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.

Mulder JE, Brien JF, Racz WJ, Takahashi T, Massey TE.

J Pharmacol Exp Ther. 2011 Feb;336(2):551-9. doi: 10.1124/jpet.110.173120. Epub 2010 Nov 15.

PMID:
21078785
18.

Influence of thymidylate synthase gene polymorphisms on total plasma homocysteine concentrations.

Ho V, Massey TE, King WD.

Mol Genet Metab. 2010 Sep;101(1):18-24. doi: 10.1016/j.ymgme.2010.05.010. Epub 2010 Jun 9.

PMID:
20580582
19.

In vivo treatment with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces organ-specific alterations in in vitro repair of DNA pyridyloxobutylation.

Brown PJ, Massey TE.

Mutat Res. 2009 Apr 26;663(1-2):15-21. doi: 10.1016/j.mrfmmm.2008.12.008. Epub 2008 Dec 31.

PMID:
19152800
20.

Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells.

Nicolescu AC, Ji Y, Comeau JL, Hill BC, Takahashi T, Brien JF, Racz WJ, Massey TE.

Toxicol Appl Pharmacol. 2008 Mar 15;227(3):370-9. doi: 10.1016/j.taap.2007.12.009. Epub 2007 Dec 15.

PMID:
18191165
21.

Failure of catalase to protect against aflatoxin B1-induced mouse lung tumorigenicity.

Guindon KA, Foley JF, Maronpot RR, Massey TE.

Toxicol Appl Pharmacol. 2008 Mar 1;227(2):179-83. Epub 2007 Oct 24.

PMID:
18155117
22.

Repair of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA pyridyloxobutylation by nucleotide excision repair.

Brown PJ, Bedard LL, Massey TE.

Cancer Lett. 2008 Feb 18;260(1-2):48-55. Epub 2007 Nov 26.

PMID:
18037231
23.

Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes.

Brown PJ, Bedard LL, Reid KR, Petsikas D, Massey TE.

Drug Metab Dispos. 2007 Nov;35(11):2086-94. Epub 2007 Aug 23.

PMID:
17717079
24.

Elevation of 8-hydroxydeoxyguanosine in DNA from isolated mouse lung cells following in vivo treatment with aflatoxin B(1).

Guindon KA, Bedard LL, Massey TE.

Toxicol Sci. 2007 Jul;98(1):57-62. Epub 2007 Mar 30.

PMID:
17400578
25.

Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones.

Nicolescu AC, Comeau JL, Hill BC, Bedard LL, Takahashi T, Brien JF, Racz WJ, Massey TE.

Toxicol Appl Pharmacol. 2007 Apr 1;220(1):60-71. Epub 2007 Jan 9.

PMID:
17316728
26.

Aflatoxin B1-induced DNA damage and its repair.

Bedard LL, Massey TE.

Cancer Lett. 2006 Sep 28;241(2):174-83. Epub 2006 Feb 3. Review.

PMID:
16458422
27.
28.

Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression.

Herzog CR, Bodon N, Pittman B, Maronpot RR, Massey TE, Anderson MW, You M, Devereux TR.

Oncogene. 2004 Apr 15;23(17):3033-9.

PMID:
14755239
29.

Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes.

Smith GB, Bend JR, Bedard LL, Reid KR, Petsikas D, Massey TE.

Drug Metab Dispos. 2003 Sep;31(9):1134-41.

PMID:
12920169
30.

Differential effects of pirfenidone on acute pulmonary injury and ensuing fibrosis in the hamster model of amiodarone-induced pulmonary toxicity.

Card JW, Racz WJ, Brien JF, Margolin SB, Massey TE.

Toxicol Sci. 2003 Sep;75(1):169-80. Epub 2003 Jun 27.

PMID:
12832656
31.

Perturbations of the Ink4a/Arf gene locus in aflatoxin B1-induced mouse lung tumors.

Tam AS, Devereux TR, Patel AC, Foley JF, Maronpot RR, Massey TE.

Carcinogenesis. 2003 Jan;24(1):121-32.

PMID:
12538357
33.

Investigation of the role of lipoxygenase in bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung.

Bedard LL, Smith GB, Reid KR, Petsikas D, Massey TE.

Chem Res Toxicol. 2002 Oct;15(10):1267-73.

PMID:
12387624
34.

Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis.

Chung WH, Bennett BM, Racz WJ, Brien JF, Massey TE.

Am J Physiol Lung Cell Mol Physiol. 2001 Nov;281(5):L1180-8.

35.

Effects of vitamin E on cytotoxicity of amiodarone and N-desethylamiodarone in isolated hamster lung cells.

Bolt MW, Racz WJ, Brien JF, Massey TE.

Toxicology. 2001 Sep 25;166(3):109-18.

PMID:
11543907
36.
37.

Human lung microsomal cytochrome P4501A1 (CYP1A1) activities: impact of smoking status and CYP1A1, aryl hydrocarbon receptor, and glutathione S-transferase M1 genetic polymorphisms.

Smith GB, Harper PA, Wong JM, Lam MS, Reid KR, Petsikas D, Massey TE.

Cancer Epidemiol Biomarkers Prev. 2001 Aug;10(8):839-53.

38.

Mechanisms of aflatoxin B1 lung tumorigenesis.

Massey TE, Smith GB, Tam AS.

Exp Lung Res. 2000 Dec;26(8):673-83. Review.

PMID:
11195464
39.
40.
41.

Biotransformation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in freshly isolated human lung cells.

Smith GB, Castonguay A, Donnelly PJ, Reid KR, Petsikas D, Massey TE.

Carcinogenesis. 1999 Sep;20(9):1809-18. Erratum in: Carcinogenesis 2000 Jun;21(6):1267.

PMID:
10469628
42.

High frequency and heterogeneous distribution of p53 mutations in aflatoxin B1-induced mouse lung tumors.

Tam AS, Foley JF, Devereux TR, Maronpot RR, Massey TE.

Cancer Res. 1999 Aug 1;59(15):3634-40.

43.

Effects of dietary vitamin E supplementation on pulmonary morphology and collagen deposition in amiodarone- and vehicle-treated hamsters.

Card JW, Leeder RG, Racz WJ, Brien JF, Bray TM, Massey TE.

Toxicology. 1999 Apr 15;133(2-3):75-84.

PMID:
10378474
44.

Differential susceptibilities of isolated hamster lung cell types to amiodarone toxicity.

Bolt MW, Racz WJ, Brien JF, Bray TM, Massey TE.

Can J Physiol Pharmacol. 1998 Jul-Aug;76(7-8):721-7.

PMID:
10030452
45.

Amiodarone-induced disruption of hamster lung and liver mitochondrial function: lack of association with thiobarbituric acid-reactive substance production.

Card JW, Lalonde BR, Rafeiro E, Tam AS, Racz WJ, Brien JF, Bray TM, Massey TE.

Toxicol Lett. 1998 Sep 1;98(1-2):41-50.

PMID:
9776560
46.

Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution.

Watson MA, Stewart RK, Smith GB, Massey TE, Bell DA.

Carcinogenesis. 1998 Feb;19(2):275-80.

PMID:
9498276
47.

ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene.

Loe DW, Stewart RK, Massey TE, Deeley RG, Cole SP.

Mol Pharmacol. 1997 Jun;51(6):1034-41.

PMID:
9187270
48.

Biotransformation of aflatoxin B1 in human lung.

Donnelly PJ, Stewart RK, Ali SL, Conlan AA, Reid KR, Petsikas D, Massey TE.

Carcinogenesis. 1996 Nov;17(11):2487-94.

PMID:
8968067
49.

Glutathione S-transferase-catalyzed conjugation of bioactivated aflatoxin B1 in rabbit lung and liver.

Stewart RK, Serabjit-Singh CJ, Massey TE.

Toxicol Appl Pharmacol. 1996 Oct;140(2):499-507.

PMID:
8887467
50.

Activation of K-ras in aflatoxin B1-induced lung tumors from AC3F1 (A/J x C3H/HeJ) mice.

Donnelly PJ, Devereux TR, Foley JF, Maronpot RR, Anderson MW, Massey TE.

Carcinogenesis. 1996 Aug;17(8):1735-40.

PMID:
8761434

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