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Items: 6


Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy Are Identified in Ovarian Tumors by Bivalent Chromatin Domains at Initial Diagnosis.

Curry E, Zeller C, Masrour N, Patten DK, Gallon J, Wilhelm-Benartzi CS, Ghaem-Maghami S, Bowtell DD, Brown R.

Cancer Res. 2018 Mar 15;78(6):1383-1391. doi: 10.1158/0008-5472.CAN-17-1650. Epub 2018 Jan 16.


Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer.

Flanagan JM, Wilson A, Koo C, Masrour N, Gallon J, Loomis E, Flower K, Wilhelm-Benartzi C, Hergovich A, Cunnea P, Gabra H, Braicu EI, Sehouli J, Darb-Esfahani S, Vanderstichele A, Vergote I, Kreuzinger C, Castillo-Tong DC, Wisman GBA, Berns EM, Siddiqui N, Paul J, Brown R.

Clin Cancer Res. 2017 May 1;23(9):2213-2222. doi: 10.1158/1078-0432.CCR-16-1754. Epub 2016 Sep 23.


Promoter CpG island methylation of genes in key cancer pathways associates with clinical outcome in high-grade serous ovarian cancer.

Dai W, Zeller C, Masrour N, Siddiqui N, Paul J, Brown R.

Clin Cancer Res. 2013 Oct 15;19(20):5788-5797. doi: 10.1158/1078-0432.CCR-13-1217. Epub 2013 Aug 21.


The DNA methylomes of serous borderline tumors reveal subgroups with malignant- or benign-like profiles.

Zeller C, Dai W, Curry E, Siddiq A, Walley A, Masrour N, Kitsou-Mylona I, Anderson G, Ghaem-Maghami S, Brown R, El-Bahrawy M.

Am J Pathol. 2013 Mar;182(3):668-77. doi: 10.1016/j.ajpath.2012.11.040. Epub 2013 Jan 25.


Loss of O⁶-methylguanine-DNA methyltransferase confers collateral sensitivity to carmustine in topoisomerase II-mediated doxorubicin resistant triple negative breast cancer cells.

Raguz S, Adams C, Masrour N, Rasul S, Papoutsoglou P, Hu Y, Cazzanelli G, Zhou Y, Patel N, Coombes C, Yagüe E.

Biochem Pharmacol. 2013 Jan 15;85(2):186-96. doi: 10.1016/j.bcp.2012.10.020. Epub 2012 Oct 30.


Cleft lip with cleft palate, ankyloglossia, and hypodontia are associated with TBX22 mutations.

Kantaputra PN, Paramee M, Kaewkhampa A, Hoshino A, Lees M, McEntagart M, Masrour N, Moore GE, Pauws E, Stanier P.

J Dent Res. 2011 Apr;90(4):450-5. doi: 10.1177/0022034510391052. Epub 2011 Jan 19.


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