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Items: 1 to 50 of 369

1.

Effect of Cefiderocol, a Siderophore Cephalosporin, on QT/QTc Interval in Healthy Adult Subjects.

Sanabria C, Migoya E, Mason JW, Stanworth SH, Katsube T, Machida M, Narukawa Y, Den Nagata T.

Clin Ther. 2019 Sep;41(9):1724-1736.e4. doi: 10.1016/j.clinthera.2019.07.006. Epub 2019 Aug 1.

2.

Correction of the QRS duration for heart rate.

Mason JW, Strauss DG, Vaglio M, Badilini F.

J Electrocardiol. 2019 May - Jun;54:1-4. doi: 10.1016/j.jelectrocard.2019.02.005. Epub 2019 Feb 12.

PMID:
30782546
3.

Assessment of Multi-Ion Channel Block in a Phase I Randomized Study Design: Results of the CiPA Phase I ECG Biomarker Validation Study.

Vicente J, Zusterzeel R, Johannesen L, Ochoa-Jimenez R, Mason JW, Sanabria C, Kemp S, Sager PT, Patel V, Matta MK, Liu J, Florian J, Garnett C, Stockbridge N, Strauss DG.

Clin Pharmacol Ther. 2019 Apr;105(4):943-953. doi: 10.1002/cpt.1303. Epub 2019 Jan 18.

4.

Comparison of Electrocardiographic Biomarkers for Differentiating Drug-Induced Single vs. Multiple Cardiac Ion Channel Block.

Brockway M, Mason JW, Brockway BP.

Clin Transl Sci. 2019 May;12(3):257-266. doi: 10.1111/cts.12596. Epub 2019 Jan 28.

5.

Electrocardiographic Effects of a Supratherapeutic Dose of WCK 2349, a Benzoquinolizine Fluoroquinolone.

Mason JW, Chugh R, Patel A, Gutte R, Bhatia A.

Clin Transl Sci. 2019 Jan;12(1):47-52. doi: 10.1111/cts.12594. Epub 2018 Nov 27.

6.

Evaluation of the Cardiac Safety of Long-Acting Endectocide Moxidectin in a Randomized Concentration-QT Study.

Kinrade SA, Mason JW, Sanabria CR, Rayner CR, Bullock JM, Stanworth SH, Sullivan MT.

Clin Transl Sci. 2018 Nov;11(6):582-589. doi: 10.1111/cts.12583. Epub 2018 Sep 19.

7.

Salutary Effects of the PULVAD, a Novel Implantable Counterpulsation Assist Device, on Cardiac Mechanoenergetics.

Kontogiannis C, Aravantinos D, Nanas I, Kapelios CJ, Marinakis S, Vakrou S, Sarchosi S, Perrea DN, Mason JW, Nanas JN, Malliaras K.

ASAIO J. 2019 Jul;65(5):473-480. doi: 10.1097/MAT.0000000000000838.

PMID:
29877888
8.

Correction: Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.

Vicente J, Johannesen L, Hosseini M, Mason JW, Sager PT, Pueyo E, Strauss DG.

PLoS One. 2018 May 21;13(5):e0197952. doi: 10.1371/journal.pone.0197952. eCollection 2018.

9.

Comparison of Two Highly Automated ECG Algorithms for Detection of Drug-Induced Cardiac Ion Channel Block.

Brockway M, Fossa AA, Mason JW.

Clin Pharmacol Ther. 2018 Aug;104(2):356-363. doi: 10.1002/cpt.934. Epub 2017 Dec 8.

10.

Debatable issues in automated ECG reporting.

Macfarlane PW, Mason JW, Kligfield P, Sommargren CE, Drew B, van Dam P, Abächerli R, Albert DE, Hodges M.

J Electrocardiol. 2017 Nov - Dec;50(6):833-840. doi: 10.1016/j.jelectrocard.2017.08.027. Epub 2017 Sep 1.

PMID:
28985886
11.

Cardiologist's point of view: Novel ECG biomarkers and in silico models for proarrhythmic risk prediction: Are we ready?

Mason JW.

J Electrocardiol. 2017 Nov - Dec;50(6):825-827. doi: 10.1016/j.jelectrocard.2017.08.011. Epub 2017 Aug 15.

PMID:
28919218
12.

Stolonidiol: Synthesis, Target Identification, and Mechanism for Choline Acetyltransferase Activation.

Mason JW, Schmid CL, Bohn LM, Roush WR.

J Am Chem Soc. 2017 Apr 26;139(16):5865-5869. doi: 10.1021/jacs.7b01083. Epub 2017 Apr 17.

PMID:
28414442
13.

Common Genetic Variant Risk Score Is Associated With Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study.

Strauss DG, Vicente J, Johannesen L, Blinova K, Mason JW, Weeke P, Behr ER, Roden DM, Woosley R, Kosova G, Rosenberg MA, Newton-Cheh C.

Circulation. 2017 Apr 4;135(14):1300-1310. doi: 10.1161/CIRCULATIONAHA.116.023980. Epub 2017 Feb 17.

14.

Moxifloxacin Increases Heart Rate in Humans.

Mason JW, Moon TE.

Antibiotics (Basel). 2017 Feb 5;6(1). pii: E5. doi: 10.3390/antibiotics6010005.

15.

Antimicrobials and QT prolongation.

Mason JW.

J Antimicrob Chemother. 2017 May 1;72(5):1272-1274. doi: 10.1093/jac/dkw591.

PMID:
28160473
16.

Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.

Vicente J, Johannesen L, Hosseini M, Mason JW, Sager PT, Pueyo E, Strauss DG.

PLoS One. 2016 Dec 30;11(12):e0163619. doi: 10.1371/journal.pone.0163619. eCollection 2016. Erratum in: PLoS One. 2018 May 21;13(5):e0197952.

17.

Electrocardiographic Effects of a Supratherapeutic Dose of Oritavancin.

Mason JW, Bellibas SE, Huang NY, Sanabria CR, Darpo B.

Clin Pharmacol Drug Dev. 2016 Nov;5(6):502-508. doi: 10.1002/cpdd.268. Epub 2016 Jul 18.

PMID:
27138652
18.

A fundamental relationship between intraventricular conduction and heart rate.

Mason JW, Badilini F, Vaglio M, Lux RL, Aysin B, Moon TE, Heinz B, Strachan I.

J Electrocardiol. 2016 May-Jun;49(3):362-70. doi: 10.1016/j.jelectrocard.2016.03.008. Epub 2016 Mar 5.

PMID:
27034123
19.

Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure.

Kontogiannis CD, Malliaras K, Kapelios CJ, Mason JW, Nanas JN.

World J Transplant. 2016 Mar 24;6(1):115-24. doi: 10.5500/wjt.v6.i1.115. Review.

20.

Sex differences in drug-induced changes in ventricular repolarization.

Vicente J, Johannesen L, Mason JW, Pueyo E, Stockbridge N, Strauss DG.

J Electrocardiol. 2015 Nov-Dec;48(6):1081-7. doi: 10.1016/j.jelectrocard.2015.08.004. Epub 2015 Aug 4.

PMID:
26324176
21.

Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.

Johannesen L, Vicente J, Mason JW, Erato C, Sanabria C, Waite-Labott K, Hong M, Lin J, Guo P, Mutlib A, Wang J, Crumb WJ, Blinova K, Chan D, Stohlman J, Florian J, Ugander M, Stockbridge N, Strauss DG.

Clin Pharmacol Ther. 2016 Feb;99(2):214-23. doi: 10.1002/cpt.205. Epub 2015 Nov 28.

22.

Lacosamide cardiac safety: clinical trials in patients with partial-onset seizures.

Rudd GD, Haverkamp W, Mason JW, Wenger T, Jay G, Hebert D, Doty P, Horstmann R.

Acta Neurol Scand. 2015 Nov;132(5):355-63. doi: 10.1111/ane.12414. Epub 2015 Apr 30.

PMID:
25933358
23.

Comprehensive T wave morphology assessment in a randomized clinical study of dofetilide, quinidine, ranolazine, and verapamil.

Vicente J, Johannesen L, Mason JW, Crumb WJ, Pueyo E, Stockbridge N, Strauss DG.

J Am Heart Assoc. 2015 Apr 13;4(4). pii: e001615. doi: 10.1161/JAHA.114.001615.

24.

Corrigendum to "New age- and sex-specific criteria for QT prolongation based on rate correction formulas that minimize bias at the upper normal limits" (Internat J Cardiol 2014, IJCA 174/3 [535-540]).

Rautaharju PM, Mason JW, Akiyama T.

Int J Cardiol. 2015 Jan 15;178:299. doi: 10.1016/j.ijcard.2014.11.073. Epub 2014 Nov 14. No abstract available.

PMID:
25639760
25.

Automated measurements for individualized heart rate correction of the QT interval.

Mason JW, Moon TE.

Clin Trials. 2015 Apr;12(2):149-55. doi: 10.1177/1740774514566332. Epub 2015 Jan 9.

PMID:
25576068
26.

Timing of pre-dose baseline electrocardiograms in clinical trials: increased sampling over a prolonged baseline period worsens variance of QTc.

Mason JW.

J Electrocardiol. 2014 Sep-Oct;47(5):716-20. doi: 10.1016/j.jelectrocard.2014.07.006. Epub 2014 Jul 8.

PMID:
25060126
27.

Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.

Johannesen L, Vicente J, Mason JW, Sanabria C, Waite-Labott K, Hong M, Guo P, Lin J, Sørensen JS, Galeotti L, Florian J, Ugander M, Stockbridge N, Strauss DG.

Clin Pharmacol Ther. 2014 Nov;96(5):549-58. doi: 10.1038/clpt.2014.155. Epub 2014 Jul 23.

PMID:
25054430
28.

New age- and sex-specific criteria for QT prolongation based on rate correction formulas that minimize bias at the upper normal limits.

Rautaharju PM, Mason JW, Akiyama T.

Int J Cardiol. 2014 Jul 1;174(3):535-40. doi: 10.1016/j.ijcard.2014.04.133. Epub 2014 Apr 21. Erratum in: Int J Cardiol. 2015 Jan 15;178:299.

PMID:
24825030
29.
30.

Electrocardiographic and cardiovascular diagnostic characteristics of patients receiving long-term opioid therapy for pain.

Mason JW, Schwertschlag US, Klutzaritz V, Canafax DM.

J Opioid Manag. 2014 Mar-Apr;10(2):103-9. doi: 10.5055/jom.2014.0199.

PMID:
24715665
31.

Use and cardiovascular safety of transdermal and other granisetron preparations in cancer management.

Mason JW, Moon TE.

Cancer Manag Res. 2013 Jul 29;5:179-85. doi: 10.2147/CMAR.S34352. Print 2013.

32.

Editorial commentary: the methadone menace.

Mason JW.

Clin Infect Dis. 2013 Oct;57(8):1195-6. doi: 10.1093/cid/cit469. Epub 2013 Jul 29. No abstract available.

PMID:
23899680
33.

Basic research on myocarditis: superb but unrequited.

Mason JW.

J Am Coll Cardiol. 2013 Nov 5;62(19):1746-7. doi: 10.1016/j.jacc.2013.06.030. Epub 2013 Jul 17. No abstract available.

34.

Cardiac imaging approaches to evaluate drug-induced myocardial dysfunction.

Christian JB, Finkle JK, Ky B, Douglas PS, Gutstein DE, Hockings PD, Lainee P, Lenihan DJ, Mason JW, Sager PT, Todaro TG, Hicks KA, Kane RC, Ko HS, Lindenfeld J, Michelson EL, Milligan J, Munley JY, Raichlen JS, Shahlaee A, Strnadova C, Ye B, Turner JR.

Am Heart J. 2012 Dec;164(6):846-55. doi: 10.1016/j.ahj.2012.09.001. Epub 2012 Oct 26. Review.

35.

Xanthates as synthetic equivalents of oxyacyl radicals: access to lactones under tin-free conditions.

Davy JA, Mason JW, Moreau B, Wulff JE.

J Org Chem. 2012 Jul 20;77(14):6332-9. doi: 10.1021/jo300939f. Epub 2012 Jul 5.

PMID:
22708663
36.

Pharmacokinetics and repolarization effects of intravenous and transdermal granisetron.

Mason JW, Selness DS, Moon TE, O'Mahony B, Donachie P, Howell J.

Clin Cancer Res. 2012 May 15;18(10):2913-21. doi: 10.1158/1078-0432.CCR-11-2785. Epub 2012 Mar 27.

37.

The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.

Bromba CM, Mason JW, Brant MG, Chan T, Lunke MD, Petric M, Boulanger MJ, Wulff JE.

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7137-41. doi: 10.1016/j.bmcl.2011.09.076. Epub 2011 Sep 24.

PMID:
22001088
38.

Structural characterization and epitope mapping of the glutamic acid/alanine-rich protein from Trypanosoma congolense: defining assembly on the parasite cell surface.

Loveless BC, Mason JW, Sakurai T, Inoue N, Razavi M, Pearson TW, Boulanger MJ.

J Biol Chem. 2011 Jun 10;286(23):20658-65. doi: 10.1074/jbc.M111.218941. Epub 2011 Apr 6.

39.

Oritavancin, a new lipoglycopeptide antibiotic: results from a thorough QT study.

Darpo B, Lee SK, Moon TE, Sills N, Mason JW.

J Clin Pharmacol. 2010 Aug;50(8):895-903. doi: 10.1177/0091270009355449. Epub 2010 May 19.

PMID:
20484618
40.

Evaluation of ventricular arrhythmias in early clinical pharmacology trials and potential consequences for later development.

Min SS, Turner JR, Nada A, DiMino TL, Hynie I, Kleiman R, Kowey P, Krucoff MW, Mason JW, Phipps A, Newton-Cheh C, Pordy R, Strnadova C, Targum S, Uhl K, Finkle J.

Am Heart J. 2010 May;159(5):716-29. doi: 10.1016/j.ahj.2010.02.004. Review.

PMID:
20435178
41.

Pharmacokinetics and pharmacodynamics of three moxifloxacin dosage forms: implications for blinding in active-controlled cardiac repolarization studies.

Mason JW, Florian JA Jr, Garnett CE, Moon TE, Selness DS, Spaulding RR.

J Clin Pharmacol. 2010 Nov;50(11):1249-59. doi: 10.1177/0091270009356298. Epub 2010 Feb 9.

PMID:
20145260
42.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part VI: acute ischemia/infarction: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology.

Wagner GS, Macfarlane P, Wellens H, Josephson M, Gorgels A, Mirvis DM, Pahlm O, Surawicz B, Kligfield P, Childers R, Gettes LS, Bailey JJ, Deal BJ, Gorgels A, Hancock EW, Kors JA, Mason JW, Okin P, Rautaharju PM, van Herpen G; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

J Am Coll Cardiol. 2009 Mar 17;53(11):1003-11. doi: 10.1016/j.jacc.2008.12.016. Review. No abstract available.

43.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part V: electrocardiogram changes associated with cardiac chamber hypertrophy: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology.

Hancock EW, Deal BJ, Mirvis DM, Okin P, Kligfield P, Gettes LS, Bailey JJ, Childers R, Gorgels A, Josephson M, Kors JA, Macfarlane P, Mason JW, Pahlm O, Rautaharju PM, Surawicz B, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

J Am Coll Cardiol. 2009 Mar 17;53(11):992-1002. doi: 10.1016/j.jacc.2008.12.015. Review. No abstract available.

44.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology.

Rautaharju PM, Surawicz B, Gettes LS, Bailey JJ, Childers R, Deal BJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

J Am Coll Cardiol. 2009 Mar 17;53(11):982-91. doi: 10.1016/j.jacc.2008.12.014. Review. No abstract available.

45.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology.

Surawicz B, Childers R, Deal BJ, Gettes LS, Bailey JJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, Rautaharju PM, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

J Am Coll Cardiol. 2009 Mar 17;53(11):976-81. doi: 10.1016/j.jacc.2008.12.013. Review. No abstract available.

46.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology.

Surawicz B, Childers R, Deal BJ, Gettes LS, Bailey JJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, Rautaharju PM, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

Circulation. 2009 Mar 17;119(10):e235-40. doi: 10.1161/CIRCULATIONAHA.108.191095. Epub 2009 Feb 19. Review. No abstract available.

PMID:
19228822
47.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology.

Rautaharju PM, Surawicz B, Gettes LS, Bailey JJ, Childers R, Deal BJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

Circulation. 2009 Mar 17;119(10):e241-50. doi: 10.1161/CIRCULATIONAHA.108.191096. Epub 2009 Feb 19. Review. No abstract available.

PMID:
19228821
48.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part V: electrocardiogram changes associated with cardiac chamber hypertrophy: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology.

Hancock EW, Deal BJ, Mirvis DM, Okin P, Kligfield P, Gettes LS, Bailey JJ, Childers R, Gorgels A, Josephson M, Kors JA, Macfarlane P, Mason JW, Pahlm O, Rautaharju PM, Surawicz B, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

Circulation. 2009 Mar 17;119(10):e251-61. doi: 10.1161/CIRCULATIONAHA.108.191097. Epub 2009 Feb 19. Review. No abstract available.

PMID:
19228820
49.

AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part VI: acute ischemia/infarction: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology.

Wagner GS, Macfarlane P, Wellens H, Josephson M, Gorgels A, Mirvis DM, Pahlm O, Surawicz B, Kligfield P, Childers R, Gettes LS, Bailey JJ, Deal BJ, Gorgels A, Hancock EW, Kors JA, Mason JW, Okin P, Rautaharju PM, van Herpen G; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society.

Circulation. 2009 Mar 17;119(10):e262-70. doi: 10.1161/CIRCULATIONAHA.108.191098. Epub 2009 Feb 19. Review. No abstract available.

PMID:
19228819
50.

Automated QT analysis that learns from cardiologist annotations.

Strachan IG, Hughes NP, Poonawala MH, Mason JW, Tarassenko L.

Ann Noninvasive Electrocardiol. 2009 Jan;14 Suppl 1:S9-21. doi: 10.1111/j.1542-474X.2008.00259.x.

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