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Items: 3

1.

Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis.

Tripathi SK, Xu T, Feng Q, Avula B, Shi X, Pan X, Mask MM, Baerson SR, Jacob MR, Ravu RR, Khan SI, Li XC, Khan IA, Clark AM, Agarwal AK.

J Biol Chem. 2017 Oct 6;292(40):16578-16593. doi: 10.1074/jbc.M117.781773. Epub 2017 Aug 18.

2.

A potent plant-derived antifungal acetylenic acid mediates its activity by interfering with fatty acid homeostasis.

Xu T, Tripathi SK, Feng Q, Lorenz MC, Wright MA, Jacob MR, Mask MM, Baerson SR, Li XC, Clark AM, Agarwal AK.

Antimicrob Agents Chemother. 2012 Jun;56(6):2894-907. doi: 10.1128/AAC.05663-11. Epub 2012 Mar 19.

3.

The marine sponge-derived polyketide endoperoxide plakortide F acid mediates its antifungal activity by interfering with calcium homeostasis.

Xu T, Feng Q, Jacob MR, Avula B, Mask MM, Baerson SR, Tripathi SK, Mohammed R, Hamann MT, Khan IA, Walker LA, Clark AM, Agarwal AK.

Antimicrob Agents Chemother. 2011 Apr;55(4):1611-21. doi: 10.1128/AAC.01022-10. Epub 2011 Feb 7.

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