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Items: 1 to 50 of 63

1.

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity.

Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K.

Sci Adv. 2019 Sep 11;5(9):eaax8352. doi: 10.1126/sciadv.aax8352. eCollection 2019 Sep.

2.

The Underpinnings of PNPLA3-Mediated Fatty Liver Emerge.

Shang L, Mashek DG.

Hepatology. 2019 Aug 5. doi: 10.1002/hep.30888. [Epub ahead of print] No abstract available.

PMID:
31378994
3.

Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner.

Josephrajan A, Hertzel AV, Bohm EK, McBurney MW, Imai SI, Mashek DG, Kim DH, Bernlohr DA.

Diabetes. 2019 Sep;68(9):1767-1777. doi: 10.2337/db18-1367. Epub 2019 Jun 6.

PMID:
31171562
4.

Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes.

Wu H, Ploeger JM, Kamarajugadda S, Mashek DG, Mashek MT, Manivel JC, Shekels LL, Lapiro JL, Albrecht JH.

Hepatol Commun. 2019 Jan 30;3(3):406-422. doi: 10.1002/hep4.1316. eCollection 2019 Mar.

5.

DXA-Determined Regional Adiposity Relates to Insulin Resistance in a Young Adult Population with Overweight andObesity.

Bantle AE, Bosch TA, Dengel DR, Wang Q, Mashek DG, Chow LS.

J Clin Densitom. 2019 Apr - Jun;22(2):287-292. doi: 10.1016/j.jocd.2018.06.001. Epub 2018 Jun 7.

PMID:
30064815
6.

Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis.

Muratore KA, Najt CP, Livezey NM, Marti J, Mashek DG, Arriaga EA.

Anal Bioanal Chem. 2018 Jun;410(16):3629-3638. doi: 10.1007/s00216-018-1016-8. Epub 2018 Apr 17.

7.

Caloric Restriction Prevents Carcinogen-Initiated Liver Tumorigenesis in Mice.

Ploeger JM, Manivel JC, Boatner LN, Mashek DG.

Cancer Prev Res (Phila). 2017 Nov;10(11):660-670. doi: 10.1158/1940-6207.CAPR-17-0174. Epub 2017 Aug 28.

8.

Breaking fat: The regulation and mechanisms of lipophagy.

Schulze RJ, Sathyanarayan A, Mashek DG.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1178-1187. doi: 10.1016/j.bbalip.2017.06.008. Epub 2017 Jun 20. Review.

9.

Acyl-CoA Thioesterase 1 (ACOT1) Regulates PPARα to Couple Fatty Acid Flux With Oxidative Capacity During Fasting.

Franklin MP, Sathyanarayan A, Mashek DG.

Diabetes. 2017 Aug;66(8):2112-2123. doi: 10.2337/db16-1519. Epub 2017 Jun 12.

10.

Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure.

Shepherd SO, Strauss JA, Wang Q, Dube JJ, Goodpaster B, Mashek DG, Chow LS.

J Physiol. 2017 Aug 15;595(16):5587-5601. doi: 10.1113/JP274374. Epub 2017 Jun 27.

11.

Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation.

Chow LS, Mashek DG, Wang Q, Shepherd SO, Goodpaster BH, Dubé JJ.

J Appl Physiol (1985). 2017 Jul 1;123(1):71-78. doi: 10.1152/japplphysiol.00209.2017. Epub 2017 Apr 27.

12.

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism.

Sathyanarayan A, Mashek MT, Mashek DG.

Cell Rep. 2017 Apr 4;19(1):1-9. doi: 10.1016/j.celrep.2017.03.026.

13.

Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation.

Kamarajugadda S, Becker JR, Hanse EA, Mashek DG, Mashek MT, Hendrickson AM, Mullany LK, Albrecht JH.

Oncotarget. 2016 Jul 26;7(30):47674-47686. doi: 10.18632/oncotarget.10274.

14.

Regulation of Glucose Metabolism - A Perspective From Cell Bioprocessing.

Mulukutla BC, Yongky A, Le T, Mashek DG, Hu WS.

Trends Biotechnol. 2016 Aug;34(8):638-651. doi: 10.1016/j.tibtech.2016.04.012. Epub 2016 Jun 2. Review.

PMID:
27265890
15.

Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.

Zhang W, Bu SY, Mashek MT, O-Sullivan I, Sibai Z, Khan SA, Ilkayeva O, Newgard CB, Mashek DG, Unterman TG.

Cell Rep. 2016 Apr 12;15(2):349-59. doi: 10.1016/j.celrep.2016.03.021. Epub 2016 Mar 31.

16.

Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption.

Bowman TA, O'Keeffe KR, D'Aquila T, Yan QW, Griffin JD, Killion EA, Salter DM, Mashek DG, Buhman KK, Greenberg AS.

Mol Metab. 2016 Jan 11;5(3):210-220. doi: 10.1016/j.molmet.2016.01.001. eCollection 2016 Mar.

17.

Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis.

Khan SA, Wollaston-Hayden EE, Markowski TW, Higgins L, Mashek DG.

J Lipid Res. 2015 Dec;56(12):2260-72. doi: 10.1194/jlr.M056812. Epub 2015 Sep 28.

18.

MUFAs.

Mashek DG, Wu C.

Adv Nutr. 2015 May 15;6(3):276-7. doi: 10.3945/an.114.005926. Print 2015 May. No abstract available.

19.

Hepatic lipid droplet biology: Getting to the root of fatty liver.

Mashek DG, Khan SA, Sathyanarayan A, Ploeger JM, Franklin MP.

Hepatology. 2015 Sep;62(3):964-7. doi: 10.1002/hep.27839. Epub 2015 May 9. Review.

20.

ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling.

Khan SA, Sathyanarayan A, Mashek MT, Ong KT, Wollaston-Hayden EE, Mashek DG.

Diabetes. 2015 Feb;64(2):418-26. doi: 10.2337/db14-0325.

21.

Lipocalin 2 regulates brown fat activation via a nonadrenergic activation mechanism.

Zhang Y, Guo H, Deis JA, Mashek MG, Zhao M, Ariyakumar D, Armien AG, Bernlohr DA, Mashek DG, Chen X.

J Biol Chem. 2014 Aug 8;289(32):22063-77. doi: 10.1074/jbc.M114.559104. Epub 2014 Jun 10.

22.

Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation.

Chow LS, Mashek DG, Austin E, Eberly LE, Persson XM, Mashek MT, Seaquist ER, Jensen MD.

Am J Physiol Endocrinol Metab. 2014 Jul 1;307(1):E124-31. doi: 10.1152/ajpendo.00166.2014. Epub 2014 May 20.

23.

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism.

Ong KT, Mashek MT, Davidson NO, Mashek DG.

J Lipid Res. 2014 May;55(5):808-15. doi: 10.1194/jlr.M039867. Epub 2014 Mar 8.

24.

Serum TAG analysis differentiates between genetic and obesity-associated NAFLD.

Mashek DG, Greenberg AS.

Diabetes. 2014 Jan;63(1):42-4. doi: 10.2337/db13-1500. No abstract available.

25.

Hepatic fatty acid trafficking: multiple forks in the road.

Mashek DG.

Adv Nutr. 2013 Nov 6;4(6):697-710. doi: 10.3945/an.113.004648. eCollection 2013 Nov. Review.

26.

Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells.

Mamedova LK, Yuan K, Laudick AN, Fleming SD, Mashek DG, Bradford BJ.

J Nutr Biochem. 2013 Aug;24(8):1499-507. doi: 10.1016/j.jnutbio.2012.12.009. Epub 2013 Mar 1.

27.

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation.

Ong KT, Mashek MT, Bu SY, Mashek DG.

FASEB J. 2013 Jan;27(1):313-21. doi: 10.1096/fj.12-213454. Epub 2012 Sep 19.

28.

Algal swimming velocities signal fatty acid accumulation.

Hansen TJ, Hondzo M, Mashek MT, Mashek DG, Lefebvre PA.

Biotechnol Bioeng. 2013 Jan;110(1):143-52. doi: 10.1002/bit.24619. Epub 2012 Aug 10.

PMID:
22833390
29.

AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity.

Zhang W, Zhang X, Wang H, Guo X, Li H, Wang Y, Xu X, Tan L, Mashek MT, Zhang C, Chen Y, Mashek DG, Foretz M, Zhu C, Zhou H, Liu X, Viollet B, Wu C, Huo Y.

Diabetes. 2012 Dec;61(12):3114-25. doi: 10.2337/db11-1373. Epub 2012 Jul 24. Retraction in: Diabetes. 2013 Mar;62(3):998.

30.

Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice.

Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Ong KT, Woo SL, Walzem RL, Mashek DG, Dong H, Lu F, Wei L, Huo Y, Wu C.

PLoS One. 2012;7(6):e39286. doi: 10.1371/journal.pone.0039286. Epub 2012 Jun 29.

31.

Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α.

Hanse EA, Mashek DG, Becker JR, Solmonson AD, Mullany LK, Mashek MT, Towle HC, Chau AT, Albrecht JH.

Cell Cycle. 2012 Jul 15;11(14):2681-90. doi: 10.4161/cc.21019. Epub 2012 Jul 15.

32.

Acute free fatty acid elevation eliminates endurance training effect on insulin sensitivity.

Chow LS, Seaquist ER, Eberly LE, Mashek MT, Schimke JM, Nair KS, Mashek DG.

J Clin Endocrinol Metab. 2012 Aug;97(8):2890-7. doi: 10.1210/jc.2012-1515. Epub 2012 May 25.

33.

Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.

Huo Y, Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Fan YY, Ong KT, Woo SL, Chapkin RS, Mashek DG, Chen Y, Dong H, Lu F, Wei L, Wu C.

J Biol Chem. 2012 Jun 15;287(25):21492-500. doi: 10.1074/jbc.M112.370379. Epub 2012 May 3.

34.

The role of lipid droplets in metabolic disease in rodents and humans.

Greenberg AS, Coleman RA, Kraemer FB, McManaman JL, Obin MS, Puri V, Yan QW, Miyoshi H, Mashek DG.

J Clin Invest. 2011 Jun;121(6):2102-10. doi: 10.1172/JCI46069. Epub 2011 Jun 1. Review.

35.

Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling.

Coleman RA, Mashek DG.

Chem Rev. 2011 Oct 12;111(10):6359-86. doi: 10.1021/cr100404w. Epub 2011 Jun 1. Review. No abstract available.

36.

Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1.

Stapleton CM, Mashek DG, Wang S, Nagle CA, Cline GW, Thuillier P, Leesnitzer LM, Li LO, Stimmel JB, Shulman GI, Coleman RA.

PLoS One. 2011 Apr 20;6(4):e18932. doi: 10.1371/journal.pone.0018932.

37.

Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditure.

Jin D, Guo H, Bu SY, Zhang Y, Hannaford J, Mashek DG, Chen X.

FASEB J. 2011 Feb;25(2):754-64. doi: 10.1096/fj.10-165175. Epub 2010 Oct 25.

38.

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning.

Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG.

Hepatology. 2011 Jan;53(1):116-26. doi: 10.1002/hep.24006. Epub 2010 Oct 21.

39.

Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways.

Bu SY, Mashek DG.

J Lipid Res. 2010 Nov;51(11):3270-80. doi: 10.1194/jlr.M009407. Epub 2010 Aug 26.

40.

Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism.

Schwinkendorf DR, Tsatsos NG, Gosnell BA, Mashek DG.

Int J Obes (Lond). 2011 Mar;35(3):336-44. doi: 10.1038/ijo.2010.159. Epub 2010 Aug 17.

PMID:
20714328
41.

Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis.

Aipoalani DL, O'Callaghan BL, Mashek DG, Mariash CN, Towle HC.

Endocrinology. 2010 May;151(5):2071-7. doi: 10.1210/en.2009-1058. Epub 2010 Mar 16.

42.

Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity.

Bu SY, Mashek MT, Mashek DG.

J Biol Chem. 2009 Oct 30;284(44):30474-83. doi: 10.1074/jbc.M109.036665. Epub 2009 Sep 8.

43.

Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity.

Sapiro JM, Mashek MT, Greenberg AS, Mashek DG.

J Lipid Res. 2009 Aug;50(8):1621-9. doi: 10.1194/jlr.M800614-JLR200. Epub 2009 Mar 21.

44.

Trans fats: foods, facts, and biology.

Bu SY, Mashek DG.

Minn Med. 2008 Oct;91(10):41-4.

PMID:
18991014
45.

Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2).

Wang S, Lee DP, Gong N, Schwerbrock NM, Mashek DG, Gonzalez-Baró MR, Stapleton C, Li LO, Lewin TM, Coleman RA.

Arch Biochem Biophys. 2007 Sep 15;465(2):347-58. Epub 2007 Jul 23.

46.

Long-chain acyl-CoA synthetases and fatty acid channeling.

Mashek DG, Li LO, Coleman RA.

Future Lipidol. 2007 Aug;2(4):465-476.

47.

Effects of intravenous triacylglycerol emulsions on lymphocyte responses to mitogens in fasted dairy cows undergoing intense lipomobilization.

Lacetera N, Scalia D, Mashek DG, Bernabucci U, Grummer RR.

J Dairy Res. 2007 Aug;74(3):323-8. Epub 2007 Apr 30.

PMID:
17466120
48.

Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes.

Li LO, Mashek DG, An J, Doughman SD, Newgard CB, Coleman RA.

J Biol Chem. 2006 Dec 1;281(48):37246-55. Epub 2006 Oct 6.

49.

Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet.

Mashek DG, Li LO, Coleman RA.

J Lipid Res. 2006 Sep;47(9):2004-10. Epub 2006 Jun 13.

50.

Cellular fatty acid uptake: the contribution of metabolism.

Mashek DG, Coleman RA.

Curr Opin Lipidol. 2006 Jun;17(3):274-8. Review.

PMID:
16680032

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