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Items: 1 to 50 of 179

1.

Are cell-based therapies for kidney disease safe? A systematic review of preclinical evidence.

Mihajlovic M, Wever KE, van der Made TK, de Vries RBM, Hilbrands LB, Masereeuw R.

Pharmacol Ther. 2019 Jan 22. pii: S0163-7258(19)30010-5. doi: 10.1016/j.pharmthera.2019.01.004. [Epub ahead of print] Review.

2.

Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells.

Vriend J, Hoogstraten CA, Venrooij KR, van den Berge BT, Govers LP, van Rooij A, Huigen MCDG, Schirris TJJ, Russel FGM, Masereeuw R, Wilmer MJ.

Biol Chem. 2019 Jan 29. pii: /j/bchm.ahead-of-print/hsz-2018-0446/hsz-2018-0446.xml. doi: 10.1515/hsz-2018-0446. [Epub ahead of print]

PMID:
30653465
3.

Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds.

Jansen K, Castilho M, Aarts S, Kaminski MM, Lienkamp SS, Pichler R, Malda J, Vermonden T, Jansen J, Masereeuw R.

Macromol Biosci. 2019 Feb;19(2):e1800412. doi: 10.1002/mabi.201800412. Epub 2018 Dec 13.

PMID:
30548802
4.

Renal Epithelial Monolayer Formation on Monomeric and Polymeric Catechol Functionalized Supramolecular Biomaterials.

van Gaal RC, Fedecostante M, Fransen PKH, Masereeuw R, Dankers PYW.

Macromol Biosci. 2019 Feb;19(2):e1800300. doi: 10.1002/mabi.201800300. Epub 2018 Nov 14.

PMID:
30430737
5.

Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease.

Groth C, van Groningen LFJ, Matos TR, Bremmers ME, Preijers FWMB, Dolstra H, Reicherts C, Schaap NPM, van Hooren EHG, IntHout J, Masereeuw R, Netea MG, Levine JE, Morales G, Ferrara JL, Blijlevens NMA, van Oosterhout YVJM, Stelljes M, van der Velden WJFM.

Biol Blood Marrow Transplant. 2018 Nov 3. pii: S1083-8791(18)30691-8. doi: 10.1016/j.bbmt.2018.10.020. [Epub ahead of print]

PMID:
30399420
6.

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review.

Zazuli Z, Vijverberg S, Slob E, Liu G, Carleton B, Veltman J, Baas P, Masereeuw R, Maitland-van der Zee AH.

Front Pharmacol. 2018 Sep 27;9:1111. doi: 10.3389/fphar.2018.01111. eCollection 2018.

7.

Bioengineering Organs for Blood Detoxification.

Legallais C, Kim D, Mihaila SM, Mihajlovic M, Figliuzzi M, Bonandrini B, Salerno S, Yousef Yengej FA, Rookmaaker MB, Sanchez Romero N, Sainz-Arnal P, Pereira U, Pasqua M, Gerritsen KGF, Verhaar MC, Remuzzi A, Baptista PM, De Bartolo L, Masereeuw R, Stamatialis D.

Adv Healthc Mater. 2018 Nov;7(21):e1800430. doi: 10.1002/adhm.201800430. Epub 2018 Sep 19. Review.

PMID:
30230709
8.

Adding the T to ADME: Predictive Toxicity in Renal Drug Development.

Lai RE, Masereeuw R.

AAPS J. 2018 Sep 5;20(6):98. doi: 10.1208/s12248-018-0258-x. No abstract available.

PMID:
30187254
9.

Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules.

Vormann MK, Gijzen L, Hutter S, Boot L, Nicolas A, van den Heuvel A, Vriend J, Ng CP, Nieskens TTG, van Duinen V, de Wagenaar B, Masereeuw R, Suter-Dick L, Trietsch SJ, Wilmer M, Joore J, Vulto P, Lanz HL.

AAPS J. 2018 Aug 14;20(5):90. doi: 10.1208/s12248-018-0248-z.

PMID:
30109442
10.

Renal Tubular- and Vascular Basement Membranes and their Mimicry in Engineering Vascularized Kidney Tubules.

van Genderen AM, Jansen J, Cheng C, Vermonden T, Masereeuw R.

Adv Healthc Mater. 2018 Oct;7(19):e1800529. doi: 10.1002/adhm.201800529. Epub 2018 Aug 9. Review.

PMID:
30091856
11.

Carbon Nanotube Reinforced Supramolecular Hydrogels for Bioapplications.

Mihajlovic M, Mihajlovic M, Dankers PYW, Masereeuw R, Sijbesma RP.

Macromol Biosci. 2019 Jan;19(1):e1800173. doi: 10.1002/mabi.201800173. Epub 2018 Aug 7.

PMID:
30085403
12.

Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip.

Vriend J, Nieskens TTG, Vormann MK, van den Berge BT, van den Heuvel A, Russel FGM, Suter-Dick L, Lanz HL, Vulto P, Masereeuw R, Wilmer MJ.

AAPS J. 2018 Jul 26;20(5):87. doi: 10.1208/s12248-018-0247-0.

PMID:
30051196
13.

Combining Extracellular miRNA Determination with Microfluidic 3D Cell Cultures for the Assessment of Nephrotoxicity: a Proof of Concept Study.

Suter-Dick L, Mauch L, Ramp D, Caj M, Vormann MK, Hutter S, Lanz HL, Vriend J, Masereeuw R, Wilmer MJ.

AAPS J. 2018 Jul 23;20(5):86. doi: 10.1208/s12248-018-0245-2.

PMID:
30039346
14.

Complex coacervation-based loading and tunable release of a cationic protein from monodisperse glycosaminoglycan microgels.

Schuurmans CCL, Abbadessa A, Bengtson MA, Pletikapic G, Eral HB, Koenderink G, Masereeuw R, Hennink WE, Vermonden T.

Soft Matter. 2018 Aug 1;14(30):6327-6341. doi: 10.1039/c8sm00686e.

PMID:
30024582
15.

Recellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity Screening.

Fedecostante M, Westphal KGC, Buono MF, Sanchez Romero N, Wilmer MJ, Kerkering J, Baptista PM, Hoenderop JG, Masereeuw R.

Drug Metab Dispos. 2018 Sep;46(9):1338-1350. doi: 10.1124/dmd.118.080721. Epub 2018 Jul 6.

PMID:
29980578
16.

Inhibition of Nrf2 alters cell stress induced by chronic iron exposure in human proximal tubular epithelial cells.

van Raaij SEG, Masereeuw R, Swinkels DW, van Swelm RPL.

Toxicol Lett. 2018 Oct 1;295:179-186. doi: 10.1016/j.toxlet.2018.06.1218. Epub 2018 Jun 28.

17.

Bioengineered bile ducts recapitulate key cholangiocyte functions.

Chen C, Jochems PGM, Salz L, Schneeberger K, Penning LC, van de Graaf SFJ, Beuers U, Clevers H, Geijsen N, Masereeuw R, Spee B.

Biofabrication. 2018 Jun 12;10(3):034103. doi: 10.1088/1758-5090/aac8fd.

PMID:
29848792
18.

A bioartificial kidney device with polarized secretion of immune modulators.

Chevtchik NV, Mihajlovic M, Fedecostante M, Bolhuis-Versteeg L, Sastre Toraño J, Masereeuw R, Stamatialis D.

J Tissue Eng Regen Med. 2018 Jul;12(7):1670-1678. doi: 10.1002/term.2694. Epub 2018 Jun 17.

PMID:
29764003
19.

From portable dialysis to a bioengineered kidney.

van Gelder MK, Mihaila SM, Jansen J, Wester M, Verhaar MC, Joles JA, Stamatialis D, Masereeuw R, Gerritsen KGF.

Expert Rev Med Devices. 2018 May;15(5):323-336. doi: 10.1080/17434440.2018.1462697. Epub 2018 Apr 20. Review.

PMID:
29633900
20.

Advances in predictive in vitro models of drug-induced nephrotoxicity.

Soo JY, Jansen J, Masereeuw R, Little MH.

Nat Rev Nephrol. 2018 Jun;14(6):378-393. doi: 10.1038/s41581-018-0003-9. Review.

21.

Evaluating Human Intestinal Cell Lines for Studying Dietary Protein Absorption.

Jochems PGM, Garssen J, van Keulen AM, Masereeuw R, Jeurink PV.

Nutrients. 2018 Mar 7;10(3). pii: E322. doi: 10.3390/nu10030322. Review.

22.

Quantification of cystine in human renal proximal tubule cells using liquid chromatography-tandem mass spectrometry.

Jamalpoor A, Sparidans RW, Pou Casellas C, Rood JJM, Joshi M, Masereeuw R, Janssen MJ.

Biomed Chromatogr. 2018 Aug;32(8):e4238. doi: 10.1002/bmc.4238. Epub 2018 Apr 15.

23.

Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity.

Nieskens TTG, Peters JGP, Dabaghie D, Korte D, Jansen K, Van Asbeck AH, Tavraz NN, Friedrich T, Russel FGM, Masereeuw R, Wilmer MJ.

Drug Metab Dispos. 2018 May;46(5):592-599. doi: 10.1124/dmd.117.079384. Epub 2018 Mar 7.

PMID:
29514829
24.

Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling.

Santana Machado T, Poitevin S, Paul P, McKay N, Jourde-Chiche N, Legris T, Mouly-Bandini A, Dignat-George F, Brunet P, Masereeuw R, Burtey S, Cerini C.

J Am Soc Nephrol. 2018 Mar;29(3):906-918. doi: 10.1681/ASN.2017030361. Epub 2017 Dec 8.

PMID:
29222397
25.

Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions.

Mihajlovic M, Fedecostante M, Oost MJ, Steenhuis SKP, Lentjes EGWM, Maitimu-Smeele I, Janssen MJ, Hilbrands LB, Masereeuw R.

Int J Mol Sci. 2017 Nov 26;18(12). pii: E2531. doi: 10.3390/ijms18122531.

26.

A Human Proximal Tubular Epithelial Cell Model to Explore a Knowledge Gap on Neonatal Drug Disposition.

Reda A, Raaijmakers A, Dorst SV, Pauwels CGGM, Allegaert K, Elmonem MA, Masereeuw R, den Heuvel LV, Levtchenko E, Arcolino FO.

Curr Pharm Des. 2017;23(38):5911-5918. doi: 10.2174/1381612823666171009143146.

PMID:
28990525
27.

Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model.

Schirris TJJ, Jansen J, Mihajlovic M, van den Heuvel LP, Masereeuw R, Russel FGM.

Sci Rep. 2017 Sep 6;7(1):10623. doi: 10.1038/s41598-017-10483-y.

28.

Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application.

Mihajlovic M, van den Heuvel LP, Hoenderop JG, Jansen J, Wilmer MJ, Westheim AJF, Allebes WA, Stamatialis D, Hilbrands LB, Masereeuw R.

Sci Rep. 2017 Aug 2;7(1):7103. doi: 10.1038/s41598-017-07582-1.

29.

Hydrogel-Based Cell Therapies for Kidney Regeneration: Current Trends in Biofabrication and In Vivo Repair.

Jansen K, Schuurmans CCL, Jansen J, Masereeuw R, Vermonden T.

Curr Pharm Des. 2017;23(26):3845-3857. doi: 10.2174/1381612823666170710155726. Review.

30.

Disposition and clinical implications of protein-bound uremic toxins.

Jansen J, Jankowski J, Gajjala PR, Wetzels JFM, Masereeuw R.

Clin Sci (Lond). 2017 Jun 30;131(14):1631-1647. doi: 10.1042/CS20160191. Print 2017 Jul 15. Review.

PMID:
28667064
31.

Creating a bioartificial kidney.

Masereeuw R, Stamatialis D.

Int J Artif Organs. 2017 Jul 5;40(7):323-327. doi: 10.5301/IJAO.5000581. Epub 2017 Jun 14. No abstract available.

PMID:
28623640
32.

Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters.

Caetano-Pinto P, Jamalpoor A, Ham J, Goumenou A, Mommersteeg M, Pijnenburg D, Ruijtenbeek R, Sanchez-Romero N, van Zelst B, Heil SG, Jansen J, Wilmer MJ, van Herpen CML, Masereeuw R.

Mol Pharm. 2017 Jun 5;14(6):2147-2157. doi: 10.1021/acs.molpharmaceut.7b00308. Epub 2017 May 24.

33.

Towards a bioengineered kidney: recellularization strategies for decellularized native kidney scaffolds.

Fedecostante M, Onciu OG, Westphal KGC, Masereeuw R.

Int J Artif Organs. 2017 May 9;40(4):150-158. doi: 10.5301/ijao.5000564. Epub 2017 May 8. Review.

PMID:
28430301
34.

The importance of breast cancer resistance protein to the kidneys excretory function and chemotherapeutic resistance.

Caetano-Pinto P, Jansen J, Assaraf YG, Masereeuw R.

Drug Resist Updat. 2017 Jan;30:15-27. doi: 10.1016/j.drup.2017.01.002. Epub 2017 Jan 11. Review.

PMID:
28363332
35.

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.

Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB.

PLoS One. 2017 Feb 24;12(2):e0168981. doi: 10.1371/journal.pone.0168981. eCollection 2017.

36.

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

van den Brand JA, Mutsaers HA, van Zuilen AD, Blankestijn PJ, van den Broek PH, Russel FG, Masereeuw R, Wetzels JF.

PLoS One. 2016 Dec 29;11(12):e0168117. doi: 10.1371/journal.pone.0168117. eCollection 2016.

37.

Effects of a human recombinant alkaline phosphatase during impaired mitochondrial function in human renal proximal tubule epithelial cells.

Peters E, Schirris T, van Asbeck AH, Gerretsen J, Eymael J, Ashikov A, Adjobo-Hermans MJ, Russel F, Pickkers P, Masereeuw R.

Eur J Pharmacol. 2017 Feb 5;796:149-157. doi: 10.1016/j.ejphar.2016.12.034. Epub 2016 Dec 22.

PMID:
28012971
38.

New insights into the effects of biomaterial chemistry and topography on the morphology of kidney epithelial cells.

Hulshof F, Schophuizen C, Mihajlovic M, van Blitterswijk C, Masereeuw R, de Boer J, Stamatialis D.

J Tissue Eng Regen Med. 2018 Feb;12(2):e817-e827. doi: 10.1002/term.2387. Epub 2017 Jun 20.

PMID:
27977906
39.

Effects of a human recombinant alkaline phosphatase on renal hemodynamics, oxygenation and inflammation in two models of acute kidney injury.

Peters E, Ergin B, Kandil A, Gurel-Gurevin E, van Elsas A, Masereeuw R, Pickkers P, Ince C.

Toxicol Appl Pharmacol. 2016 Dec 15;313:88-96. doi: 10.1016/j.taap.2016.10.015. Epub 2016 Oct 17.

PMID:
27760303
40.

Cardiac Hepcidin Expression Associates with Injury Independent of Iron.

van Breda GF, Bongartz LG, Zhuang W, van Swelm RP, Pertijs J, Braam B, Cramer MJ, Swinkels DW, Doevendans PA, Verhaar MC, Masereeuw R, Joles JA, Gaillard CA.

Am J Nephrol. 2016;44(5):368-378. Epub 2016 Oct 22.

41.

Fluorescently Labeled Cyclodextrin Derivatives as Exogenous Markers for Real-Time Transcutaneous Measurement of Renal Function.

Huang J, Weinfurter S, Pinto PC, Pretze M, Kränzlin B, Pill J, Federica R, Perciaccante R, Ciana LD, Masereeuw R, Gretz N.

Bioconjug Chem. 2016 Oct 19;27(10):2513-2526. Epub 2016 Sep 22.

PMID:
27611623
42.

Upscaling of a living membrane for bioartificial kidney device.

Chevtchik NV, Fedecostante M, Jansen J, Mihajlovic M, Wilmer M, Rüth M, Masereeuw R, Stamatialis D.

Eur J Pharmacol. 2016 Nov 5;790:28-35. doi: 10.1016/j.ejphar.2016.07.009. Epub 2016 Jul 6.

PMID:
27395800
43.

In vitro systems to study nephropharmacology: 2D versus 3D models.

Sánchez-Romero N, Schophuizen CM, Giménez I, Masereeuw R.

Eur J Pharmacol. 2016 Nov 5;790:36-45. doi: 10.1016/j.ejphar.2016.07.010. Epub 2016 Jul 7. Review.

PMID:
27395797
44.

An introduction to the pharmacology of kidney regeneration.

Janssen MJ, Masereeuw R.

Eur J Pharmacol. 2016 Nov 5;790:1-2. doi: 10.1016/j.ejphar.2016.06.055. Epub 2016 Jun 30. No abstract available.

PMID:
27375079
45.

Bioengineered kidney tubules efficiently excrete uremic toxins.

Jansen J, Fedecostante M, Wilmer MJ, Peters JG, Kreuser UM, van den Broek PH, Mensink RA, Boltje TJ, Stamatialis D, Wetzels JF, van den Heuvel LP, Hoenderop JG, Masereeuw R.

Sci Rep. 2016 May 31;6:26715. doi: 10.1038/srep26715.

46.

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers.

Peters E, Heuberger JAAC, Tiessen R, van Elsas A, Masereeuw R, Arend J, Stevens J, Pickkers P.

Clin Pharmacokinet. 2016 Oct;55(10):1227-1237. doi: 10.1007/s40262-016-0399-y.

47.

Fluorescence-Based Transport Assays Revisited in a Human Renal Proximal Tubule Cell Line.

Caetano-Pinto P, Janssen MJ, Gijzen L, Verscheijden L, Wilmer MJ, Masereeuw R.

Mol Pharm. 2016 Mar 7;13(3):933-44. doi: 10.1021/acs.molpharmaceut.5b00821. Epub 2016 Feb 23.

PMID:
26871298
48.

Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury.

van Swelm RP, Wetzels JF, Verweij VG, Laarakkers CM, Pertijs JC, van der Wijst J, Thévenod F, Masereeuw R, Swinkels DW.

J Am Soc Nephrol. 2016 Sep;27(9):2720-32. doi: 10.1681/ASN.2015040461. Epub 2016 Jan 29.

49.

A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity.

Nieskens TT, Peters JG, Schreurs MJ, Smits N, Woestenenk R, Jansen K, van der Made TK, Röring M, Hilgendorf C, Wilmer MJ, Masereeuw R.

AAPS J. 2016 Mar;18(2):465-75. doi: 10.1208/s12248-016-9871-8. Epub 2016 Jan 28.

50.

Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening.

Wilmer MJ, Ng CP, Lanz HL, Vulto P, Suter-Dick L, Masereeuw R.

Trends Biotechnol. 2016 Feb;34(2):156-170. doi: 10.1016/j.tibtech.2015.11.001. Epub 2015 Dec 18. Review.

PMID:
26708346

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