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Items: 1 to 50 of 190

1.

Therapy with 2'-O-Me Phosphorothioate Antisense Oligonucleotides Causes Reversible Proteinuria by Inhibiting Renal Protein Reabsorption.

Janssen MJ, Nieskens TTG, Steevels TAM, Caetano-Pinto P, den Braanker D, Mulder M, Ponstein Y, Jones S, Masereeuw R, den Besten C, Wilmer MJ.

Mol Ther Nucleic Acids. 2019 Sep 6;18:298-307. doi: 10.1016/j.omtn.2019.08.025. [Epub ahead of print]

2.

In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes.

Abyar S, Khandar AA, Salehi R, Abolfazl Hosseini-Yazdi S, Alizadeh E, Mahkam M, Jamalpoor A, White JM, Shojaei M, Aizpurua-Olaizola O, Masereeuw R, Janssen MJ.

Sci Rep. 2019 Oct 11;9(1):14686. doi: 10.1038/s41598-019-51109-9.

3.

Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease.

van der Made TK, Fedecostante M, Scotcher D, Rostami-Hodjegan A, Sastre Toraño J, Middel I, Koster AS, Gerritsen KG, Jankowski V, Jankowski J, Hoenderop JGJ, Masereeuw R, Galetin A.

Mol Pharm. 2019 Sep 27. doi: 10.1021/acs.molpharmaceut.9b00681. [Epub ahead of print]

PMID:
31525064
4.

Safety evaluation of conditionally immortalized cells for renal replacement therapy.

Mihajlovic M, Hariri S, Westphal KCG, Janssen MJ, Oost MJ, Bongiovanni L, van den Heuvel LP, de Bruin A, Hilbrands LB, Masereeuw R.

Oncotarget. 2019 Sep 3;10(51):5332-5348. doi: 10.18632/oncotarget.27152. eCollection 2019 Sep 3.

5.

Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia.

Vriend J, Peters JGP, Nieskens TTG, Škovroňová R, Blaimschein N, Schmidts M, Roepman R, Schirris TJJ, Russel FGM, Masereeuw R, Wilmer MJ.

Biochim Biophys Acta Gen Subj. 2019 Sep 11:129433. doi: 10.1016/j.bbagen.2019.129433. [Epub ahead of print]

6.

A simple method for the isolation and detailed characterization of primary human proximal tubule cells for renal replacement therapy.

Sánchez-Romero N, Martínez-Gimeno L, Caetano-Pinto P, Saez B, Sánchez-Zalabardo JM, Masereeuw R, Giménez I.

Int J Artif Organs. 2019 Aug 6:391398819866458. doi: 10.1177/0391398819866458. [Epub ahead of print]

PMID:
31385550
7.

Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion.

Jansen J, Jansen K, Neven E, Poesen R, Othman A, van Mil A, Sluijter J, Sastre Torano J, Zaal EA, Berkers CR, Esser D, Wichers HJ, van Ede K, van Duursen M, Burtey S, Verhaar MC, Meijers B, Masereeuw R.

Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16105-16110. doi: 10.1073/pnas.1821809116. Epub 2019 Jul 24.

8.

Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes.

Deltombe O, Glorieux G, Marzouki S, Masereeuw R, Schneditz D, Eloot S.

Toxins (Basel). 2019 Jul 1;11(7). pii: E385. doi: 10.3390/toxins11070385.

9.

Outcome Definition Influences the Relationship Between Genetic Polymorphisms of ERCC1, ERCC2, SLC22A2 and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients.

Zazuli Z, Otten LS, Drögemöller BI, Medeiros M, Monzon JG, Wright GEB, Kollmannsberger CK, Bedard PL, Chen Z, Gelmon KA, McGoldrick N, Kitchlu A, Vijverberg SJH, Masereeuw R, Ross CJD, Liu G, Carleton BC, Maitland-van der Zee AH.

Genes (Basel). 2019 May 10;10(5). pii: E364. doi: 10.3390/genes10050364.

10.

Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients.

Jochems PGM, van Bergenhenegouwen J, van Genderen AM, Eis ST, Wilod Versprille LJF, Wichers HJ, Jeurink PV, Garssen J, Masereeuw R.

Toxicol In Vitro. 2019 Oct;60:1-11. doi: 10.1016/j.tiv.2019.04.019. Epub 2019 May 6.

11.

Tubuloids derived from human adult kidney and urine for personalized disease modeling.

Schutgens F, Rookmaaker MB, Margaritis T, Rios A, Ammerlaan C, Jansen J, Gijzen L, Vormann M, Vonk A, Viveen M, Yengej FY, Derakhshan S, de Winter-de Groot KM, Artegiani B, van Boxtel R, Cuppen E, Hendrickx APA, van den Heuvel-Eibrink MM, Heitzer E, Lanz H, Beekman J, Murk JL, Masereeuw R, Holstege F, Drost J, Verhaar MC, Clevers H.

Nat Biotechnol. 2019 Mar;37(3):303-313. doi: 10.1038/s41587-019-0048-8. Epub 2019 Mar 4.

PMID:
30833775
12.

Are cell-based therapies for kidney disease safe? A systematic review of preclinical evidence.

Mihajlovic M, Wever KE, van der Made TK, de Vries RBM, Hilbrands LB, Masereeuw R.

Pharmacol Ther. 2019 May;197:191-211. doi: 10.1016/j.pharmthera.2019.01.004. Epub 2019 Jan 22. Review.

13.

Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells.

Vriend J, Hoogstraten CA, Venrooij KR, van den Berge BT, Govers LP, van Rooij A, Huigen MCDG, Schirris TJJ, Russel FGM, Masereeuw R, Wilmer MJ.

Biol Chem. 2019 Sep 25;400(10):1347-1358. doi: 10.1515/hsz-2018-0446.

PMID:
30653465
14.

Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds.

Jansen K, Castilho M, Aarts S, Kaminski MM, Lienkamp SS, Pichler R, Malda J, Vermonden T, Jansen J, Masereeuw R.

Macromol Biosci. 2019 Feb;19(2):e1800412. doi: 10.1002/mabi.201800412. Epub 2018 Dec 13.

PMID:
30548802
15.

Renal Epithelial Monolayer Formation on Monomeric and Polymeric Catechol Functionalized Supramolecular Biomaterials.

van Gaal RC, Fedecostante M, Fransen PKH, Masereeuw R, Dankers PYW.

Macromol Biosci. 2019 Feb;19(2):e1800300. doi: 10.1002/mabi.201800300. Epub 2018 Nov 14.

PMID:
30430737
16.

Phase I/II Trial of a Combination of Anti-CD3/CD7 Immunotoxins for Steroid-Refractory Acute Graft-versus-Host Disease.

Groth C, van Groningen LFJ, Matos TR, Bremmers ME, Preijers FWMB, Dolstra H, Reicherts C, Schaap NPM, van Hooren EHG, IntHout J, Masereeuw R, Netea MG, Levine JE, Morales G, Ferrara JL, Blijlevens NMA, van Oosterhout YVJM, Stelljes M, van der Velden WJFM.

Biol Blood Marrow Transplant. 2019 Apr;25(4):712-719. doi: 10.1016/j.bbmt.2018.10.020. Epub 2018 Nov 3.

PMID:
30399420
17.

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review.

Zazuli Z, Vijverberg S, Slob E, Liu G, Carleton B, Veltman J, Baas P, Masereeuw R, Maitland-van der Zee AH.

Front Pharmacol. 2018 Sep 27;9:1111. doi: 10.3389/fphar.2018.01111. eCollection 2018.

18.

Bioengineering Organs for Blood Detoxification.

Legallais C, Kim D, Mihaila SM, Mihajlovic M, Figliuzzi M, Bonandrini B, Salerno S, Yousef Yengej FA, Rookmaaker MB, Sanchez Romero N, Sainz-Arnal P, Pereira U, Pasqua M, Gerritsen KGF, Verhaar MC, Remuzzi A, Baptista PM, De Bartolo L, Masereeuw R, Stamatialis D.

Adv Healthc Mater. 2018 Nov;7(21):e1800430. doi: 10.1002/adhm.201800430. Epub 2018 Sep 19. Review.

PMID:
30230709
19.

Adding the T to ADME: Predictive Toxicity in Renal Drug Development.

Lai RE, Masereeuw R.

AAPS J. 2018 Sep 5;20(6):98. doi: 10.1208/s12248-018-0258-x. No abstract available.

PMID:
30187254
20.

Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules.

Vormann MK, Gijzen L, Hutter S, Boot L, Nicolas A, van den Heuvel A, Vriend J, Ng CP, Nieskens TTG, van Duinen V, de Wagenaar B, Masereeuw R, Suter-Dick L, Trietsch SJ, Wilmer M, Joore J, Vulto P, Lanz HL.

AAPS J. 2018 Aug 14;20(5):90. doi: 10.1208/s12248-018-0248-z.

PMID:
30109442
21.

Renal Tubular- and Vascular Basement Membranes and their Mimicry in Engineering Vascularized Kidney Tubules.

van Genderen AM, Jansen J, Cheng C, Vermonden T, Masereeuw R.

Adv Healthc Mater. 2018 Oct;7(19):e1800529. doi: 10.1002/adhm.201800529. Epub 2018 Aug 9. Review.

PMID:
30091856
22.

Carbon Nanotube Reinforced Supramolecular Hydrogels for Bioapplications.

Mihajlovic M, Mihajlovic M, Dankers PYW, Masereeuw R, Sijbesma RP.

Macromol Biosci. 2019 Jan;19(1):e1800173. doi: 10.1002/mabi.201800173. Epub 2018 Aug 7.

PMID:
30085403
23.

Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip.

Vriend J, Nieskens TTG, Vormann MK, van den Berge BT, van den Heuvel A, Russel FGM, Suter-Dick L, Lanz HL, Vulto P, Masereeuw R, Wilmer MJ.

AAPS J. 2018 Jul 26;20(5):87. doi: 10.1208/s12248-018-0247-0.

PMID:
30051196
24.

Combining Extracellular miRNA Determination with Microfluidic 3D Cell Cultures for the Assessment of Nephrotoxicity: a Proof of Concept Study.

Suter-Dick L, Mauch L, Ramp D, Caj M, Vormann MK, Hutter S, Lanz HL, Vriend J, Masereeuw R, Wilmer MJ.

AAPS J. 2018 Jul 23;20(5):86. doi: 10.1208/s12248-018-0245-2.

PMID:
30039346
25.

Complex coacervation-based loading and tunable release of a cationic protein from monodisperse glycosaminoglycan microgels.

Schuurmans CCL, Abbadessa A, Bengtson MA, Pletikapic G, Eral HB, Koenderink G, Masereeuw R, Hennink WE, Vermonden T.

Soft Matter. 2018 Aug 1;14(30):6327-6341. doi: 10.1039/c8sm00686e.

PMID:
30024582
26.

Recellularized Native Kidney Scaffolds as a Novel Tool in Nephrotoxicity Screening.

Fedecostante M, Westphal KGC, Buono MF, Sanchez Romero N, Wilmer MJ, Kerkering J, Baptista PM, Hoenderop JG, Masereeuw R.

Drug Metab Dispos. 2018 Sep;46(9):1338-1350. doi: 10.1124/dmd.118.080721. Epub 2018 Jul 6.

PMID:
29980578
27.

Inhibition of Nrf2 alters cell stress induced by chronic iron exposure in human proximal tubular epithelial cells.

van Raaij SEG, Masereeuw R, Swinkels DW, van Swelm RPL.

Toxicol Lett. 2018 Oct 1;295:179-186. doi: 10.1016/j.toxlet.2018.06.1218. Epub 2018 Jun 28.

28.

Bioengineered bile ducts recapitulate key cholangiocyte functions.

Chen C, Jochems PGM, Salz L, Schneeberger K, Penning LC, van de Graaf SFJ, Beuers U, Clevers H, Geijsen N, Masereeuw R, Spee B.

Biofabrication. 2018 Jun 12;10(3):034103. doi: 10.1088/1758-5090/aac8fd.

PMID:
29848792
29.

A bioartificial kidney device with polarized secretion of immune modulators.

Chevtchik NV, Mihajlovic M, Fedecostante M, Bolhuis-Versteeg L, Sastre Toraño J, Masereeuw R, Stamatialis D.

J Tissue Eng Regen Med. 2018 Jul;12(7):1670-1678. doi: 10.1002/term.2694. Epub 2018 Jun 17.

PMID:
29764003
30.

From portable dialysis to a bioengineered kidney.

van Gelder MK, Mihaila SM, Jansen J, Wester M, Verhaar MC, Joles JA, Stamatialis D, Masereeuw R, Gerritsen KGF.

Expert Rev Med Devices. 2018 May;15(5):323-336. doi: 10.1080/17434440.2018.1462697. Epub 2018 Apr 20. Review.

PMID:
29633900
31.

Advances in predictive in vitro models of drug-induced nephrotoxicity.

Soo JY, Jansen J, Masereeuw R, Little MH.

Nat Rev Nephrol. 2018 Jun;14(6):378-393. doi: 10.1038/s41581-018-0003-9. Review.

32.

Evaluating Human Intestinal Cell Lines for Studying Dietary Protein Absorption.

Jochems PGM, Garssen J, van Keulen AM, Masereeuw R, Jeurink PV.

Nutrients. 2018 Mar 7;10(3). pii: E322. doi: 10.3390/nu10030322. Review.

33.

Quantification of cystine in human renal proximal tubule cells using liquid chromatography-tandem mass spectrometry.

Jamalpoor A, Sparidans RW, Pou Casellas C, Rood JJM, Joshi M, Masereeuw R, Janssen MJ.

Biomed Chromatogr. 2018 Aug;32(8):e4238. doi: 10.1002/bmc.4238. Epub 2018 Apr 15.

34.

Expression of Organic Anion Transporter 1 or 3 in Human Kidney Proximal Tubule Cells Reduces Cisplatin Sensitivity.

Nieskens TTG, Peters JGP, Dabaghie D, Korte D, Jansen K, Van Asbeck AH, Tavraz NN, Friedrich T, Russel FGM, Masereeuw R, Wilmer MJ.

Drug Metab Dispos. 2018 May;46(5):592-599. doi: 10.1124/dmd.117.079384. Epub 2018 Mar 7.

PMID:
29514829
35.

Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling.

Santana Machado T, Poitevin S, Paul P, McKay N, Jourde-Chiche N, Legris T, Mouly-Bandini A, Dignat-George F, Brunet P, Masereeuw R, Burtey S, Cerini C.

J Am Soc Nephrol. 2018 Mar;29(3):906-918. doi: 10.1681/ASN.2017030361. Epub 2017 Dec 8.

36.

Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions.

Mihajlovic M, Fedecostante M, Oost MJ, Steenhuis SKP, Lentjes EGWM, Maitimu-Smeele I, Janssen MJ, Hilbrands LB, Masereeuw R.

Int J Mol Sci. 2017 Nov 26;18(12). pii: E2531. doi: 10.3390/ijms18122531.

37.

A Human Proximal Tubular Epithelial Cell Model to Explore a Knowledge Gap on Neonatal Drug Disposition.

Reda A, Raaijmakers A, Dorst SV, Pauwels CGGM, Allegaert K, Elmonem MA, Masereeuw R, den Heuvel LV, Levtchenko E, Arcolino FO.

Curr Pharm Des. 2017;23(38):5911-5918. doi: 10.2174/1381612823666171009143146.

PMID:
28990525
38.

Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model.

Schirris TJJ, Jansen J, Mihajlovic M, van den Heuvel LP, Masereeuw R, Russel FGM.

Sci Rep. 2017 Sep 6;7(1):10623. doi: 10.1038/s41598-017-10483-y.

39.

Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application.

Mihajlovic M, van den Heuvel LP, Hoenderop JG, Jansen J, Wilmer MJ, Westheim AJF, Allebes WA, Stamatialis D, Hilbrands LB, Masereeuw R.

Sci Rep. 2017 Aug 2;7(1):7103. doi: 10.1038/s41598-017-07582-1.

40.

Hydrogel-Based Cell Therapies for Kidney Regeneration: Current Trends in Biofabrication and In Vivo Repair.

Jansen K, Schuurmans CCL, Jansen J, Masereeuw R, Vermonden T.

Curr Pharm Des. 2017;23(26):3845-3857. doi: 10.2174/1381612823666170710155726. Review.

41.

Disposition and clinical implications of protein-bound uremic toxins.

Jansen J, Jankowski J, Gajjala PR, Wetzels JFM, Masereeuw R.

Clin Sci (Lond). 2017 Jun 30;131(14):1631-1647. doi: 10.1042/CS20160191. Print 2017 Jul 15. Review.

PMID:
28667064
42.

Creating a bioartificial kidney.

Masereeuw R, Stamatialis D.

Int J Artif Organs. 2017 Jul 5;40(7):323-327. doi: 10.5301/IJAO.5000581. Epub 2017 Jun 14. No abstract available.

PMID:
28623640
43.

Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters.

Caetano-Pinto P, Jamalpoor A, Ham J, Goumenou A, Mommersteeg M, Pijnenburg D, Ruijtenbeek R, Sanchez-Romero N, van Zelst B, Heil SG, Jansen J, Wilmer MJ, van Herpen CML, Masereeuw R.

Mol Pharm. 2017 Jun 5;14(6):2147-2157. doi: 10.1021/acs.molpharmaceut.7b00308. Epub 2017 May 24.

44.

Towards a bioengineered kidney: recellularization strategies for decellularized native kidney scaffolds.

Fedecostante M, Onciu OG, Westphal KGC, Masereeuw R.

Int J Artif Organs. 2017 May 9;40(4):150-158. doi: 10.5301/ijao.5000564. Epub 2017 May 8. Review.

PMID:
28430301
45.

The importance of breast cancer resistance protein to the kidneys excretory function and chemotherapeutic resistance.

Caetano-Pinto P, Jansen J, Assaraf YG, Masereeuw R.

Drug Resist Updat. 2017 Jan;30:15-27. doi: 10.1016/j.drup.2017.01.002. Epub 2017 Jan 11. Review.

PMID:
28363332
46.

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.

Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB.

PLoS One. 2017 Feb 24;12(2):e0168981. doi: 10.1371/journal.pone.0168981. eCollection 2017.

47.

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression.

van den Brand JA, Mutsaers HA, van Zuilen AD, Blankestijn PJ, van den Broek PH, Russel FG, Masereeuw R, Wetzels JF.

PLoS One. 2016 Dec 29;11(12):e0168117. doi: 10.1371/journal.pone.0168117. eCollection 2016.

48.

Effects of a human recombinant alkaline phosphatase during impaired mitochondrial function in human renal proximal tubule epithelial cells.

Peters E, Schirris T, van Asbeck AH, Gerretsen J, Eymael J, Ashikov A, Adjobo-Hermans MJ, Russel F, Pickkers P, Masereeuw R.

Eur J Pharmacol. 2017 Feb 5;796:149-157. doi: 10.1016/j.ejphar.2016.12.034. Epub 2016 Dec 22.

PMID:
28012971
49.

New insights into the effects of biomaterial chemistry and topography on the morphology of kidney epithelial cells.

Hulshof F, Schophuizen C, Mihajlovic M, van Blitterswijk C, Masereeuw R, de Boer J, Stamatialis D.

J Tissue Eng Regen Med. 2018 Feb;12(2):e817-e827. doi: 10.1002/term.2387. Epub 2017 Jun 20.

PMID:
27977906
50.

Effects of a human recombinant alkaline phosphatase on renal hemodynamics, oxygenation and inflammation in two models of acute kidney injury.

Peters E, Ergin B, Kandil A, Gurel-Gurevin E, van Elsas A, Masereeuw R, Pickkers P, Ince C.

Toxicol Appl Pharmacol. 2016 Dec 15;313:88-96. doi: 10.1016/j.taap.2016.10.015. Epub 2016 Oct 17.

PMID:
27760303

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