Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 33

1.

Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response.

Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ.

Pain. 2019 Aug;160(8):1740-1753. doi: 10.1097/j.pain.0000000000001571.

PMID:
31335644
2.

Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development.

Racine JJ, Stewart I, Ratiu J, Christianson G, Lowell E, Helm K, Allocco J, Maser RS, Chen YG, Lutz CM, Roopenian D, Schloss J, DiLorenzo TP, Serreze DV.

Diabetes. 2018 May;67(5):923-935. doi: 10.2337/db17-1467. Epub 2018 Feb 22.

3.

Generating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing.

Qin W, Kutny PM, Maser RS, Dion SL, Lamont JD, Zhang Y, Perry GA, Wang H.

Curr Protoc Mouse Biol. 2016 Mar 1;6(1):39-66. doi: 10.1002/9780470942390.mo150178.

4.

Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.

Hosur V, Johnson KR, Burzenski LM, Stearns TM, Maser RS, Shultz LD.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2200-9. doi: 10.1073/pnas.1323908111. Epub 2014 May 13.

5.

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.

Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732.

6.

Telomere dysfunction induces metabolic and mitochondrial compromise.

Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA.

Nature. 2011 Feb 17;470(7334):359-65. doi: 10.1038/nature09787. Epub 2011 Feb 9. Erratum in: Nature. 2011 Jul 14;475(7355):254.

7.

Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.

Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel AF, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, Wong KK.

Carcinogenesis. 2008 Apr;29(4):747-53. doi: 10.1093/carcin/bgn050. Epub 2008 Feb 17.

PMID:
18283039
8.

Alu elements mediate MYB gene tandem duplication in human T-ALL.

O'Neil J, Tchinda J, Gutierrez A, Moreau L, Maser RS, Wong KK, Li W, McKenna K, Liu XS, Feng B, Neuberg D, Silverman L, DeAngelo DJ, Kutok JL, Rothstein R, DePinho RA, Chin L, Lee C, Look AT.

J Exp Med. 2007 Dec 24;204(13):3059-66. Epub 2007 Dec 10.

9.

A detailed examination of cytokine abnormalities in Major Depressive Disorder.

Simon NM, McNamara K, Chow CW, Maser RS, Papakostas GI, Pollack MH, Nierenberg AA, Fava M, Wong KK.

Eur Neuropsychopharmacol. 2008 Mar;18(3):230-3. Epub 2007 Aug 3.

10.

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.

Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, Edkins S, Stevens C, Brennan C, Martin ES, Wiedemeyer R, Kabbarah O, Nogueira C, Histen G, Aster J, Mansour M, Duke V, Foroni L, Fielding AK, Goldstone AH, Rowe JM, Wang YA, Look AT, Stratton MR, Chin L, Futreal PA, DePinho RA.

Nature. 2007 Jun 21;447(7147):966-71. Epub 2007 May 21.

11.

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.

Maser RS, Wong KK, Sahin E, Xia H, Naylor M, Hedberg HM, Artandi SE, DePinho RA.

Mol Cell Biol. 2007 Mar;27(6):2253-65. Epub 2006 Dec 4.

12.

Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres.

Wong KK, Maser RS, Sahin E, Bailey ST, Xia H, Ji H, McNamara K, Naylor M, Bronson RT, Ghosh S, Welsh R, DePinho RA.

Oncogene. 2007 May 3;26(20):2815-21. Epub 2006 Oct 30.

PMID:
17072335
13.

Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging.

Simon NM, Smoller JW, McNamara KL, Maser RS, Zalta AK, Pollack MH, Nierenberg AA, Fava M, Wong KK.

Biol Psychiatry. 2006 Sep 1;60(5):432-5. Epub 2006 Apr 11.

PMID:
16581033
14.

K-ras activation generates an inflammatory response in lung tumors.

Ji H, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Marconcini LA, Hezel A, El-Bardeesy N, Bronson RT, Sugarbaker D, Maser RS, Shapiro SD, Wong KK.

Oncogene. 2006 Mar 30;25(14):2105-12.

PMID:
16288213
15.

Telomere induced senescence: end game signaling.

Hezel AF, Bardeesy N, Maser RS.

Curr Mol Med. 2005 Mar;5(2):145-52. Review.

PMID:
15974867
16.

Telomeres and the DNA damage response: why the fox is guarding the henhouse.

Maser RS, DePinho RA.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):979-88. Review.

PMID:
15279784
17.

Take care of your chromosomes lest cancer take care of you.

Maser RS, DePinho RA.

Cancer Cell. 2003 Jan;3(1):4-6. Review.

18.

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing.

Wong KK, Maser RS, Bachoo RM, Menon J, Carrasco DR, Gu Y, Alt FW, DePinho RA.

Nature. 2003 Feb 6;421(6923):643-8. Epub 2003 Jan 22.

PMID:
12540856
19.

Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression.

Chang S, Khoo CM, Naylor ML, Maser RS, DePinho RA.

Genes Dev. 2003 Jan 1;17(1):88-100. Erratum in: Genes Dev. 2003 Feb 15;17(4):541..

20.

Keeping telomerase in its place.

Maser RS, DePinho RA.

Nat Med. 2002 Sep;8(9):934-6. No abstract available.

PMID:
12205452
21.

Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

O'Hagan RC, Chang S, Maser RS, Mohan R, Artandi SE, Chin L, DePinho RA.

Cancer Cell. 2002 Aug;2(2):149-55.

22.

Connecting chromosomes, crisis, and cancer.

Maser RS, DePinho RA.

Science. 2002 Jul 26;297(5581):565-9. Review.

PMID:
12142527
23.

Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein.

Antoku K, Maser RS, Scully WJ Jr, Delach SM, Johnson DE.

Biochem Biophys Res Commun. 2001 Sep 7;286(5):1003-10.

PMID:
11527400
24.

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis.

Maser RS, Mirzoeva OK, Wells J, Olivares H, Williams BR, Zinkel RA, Farnham PJ, Petrini JH.

Mol Cell Biol. 2001 Sep;21(17):6006-16.

25.
26.

Analysis of the role of conserved cysteine residues in the bcl-2 oncoprotein.

Maser RS, Antoku K, Scully WJ Jr, Cho RL, Johnson DE.

Biochem Biophys Res Commun. 2000 Oct 14;277(1):171-8.

PMID:
11027659
27.

Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects.

Girard PM, Foray N, Stumm M, Waugh A, Riballo E, Maser RS, Phillips WP, Petrini J, Arlett CF, Jeggo PA.

Cancer Res. 2000 Sep 1;60(17):4881-8.

28.

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.

Lim DS, Kim ST, Xu B, Maser RS, Lin J, Petrini JH, Kastan MB.

Nature. 2000 Apr 6;404(6778):613-7.

PMID:
10766245
29.

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder.

Stewart GS, Maser RS, Stankovic T, Bressan DA, Kaplan MI, Jaspers NG, Raams A, Byrd PJ, Petrini JH, Taylor AM.

Cell. 1999 Dec 10;99(6):577-87.

30.

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.

Carney JP, Maser RS, Olivares H, Davis EM, Le Beau M, Yates JR 3rd, Hays L, Morgan WF, Petrini JH.

Cell. 1998 May 1;93(3):477-86.

31.

In situ visualization of DNA double-strand break repair in human fibroblasts.

Nelms BE, Maser RS, MacKay JF, Lagally MG, Petrini JH.

Science. 1998 Apr 24;280(5363):590-2.

32.

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.

Maser RS, Monsen KJ, Nelms BE, Petrini JH.

Mol Cell Biol. 1997 Oct;17(10):6087-96.

33.

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.

Dolganov GM, Maser RS, Novikov A, Tosto L, Chong S, Bressan DA, Petrini JH.

Mol Cell Biol. 1996 Sep;16(9):4832-41.

Supplemental Content

Loading ...
Support Center