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Items: 1 to 50 of 136


Biomarkers for aging identified in cross-sectional studies tend to be non-causative.

Nelson PG, Promislow DEL, Masel J.

J Gerontol A Biol Sci Med Sci. 2019 Jul 29. pii: glz174. doi: 10.1093/gerona/glz174. [Epub ahead of print]


Feed-forward regulation adaptively evolves via dynamics rather than topology when there is intrinsic noise.

Xiong K, Lancaster AK, Siegal ML, Masel J.

Nat Commun. 2019 Jun 3;10(1):2418. doi: 10.1038/s41467-019-10388-6.


Different mechanisms drive the maintenance of polymorphism at loci subject to strong versus weak fluctuating selection.

Bertram J, Masel J.

Evolution. 2019 May;73(5):883-896. doi: 10.1111/evo.13719. Epub 2019 Mar 20.


A Shift in Aggregation Avoidance Strategy Marks a Long-Term Direction to Protein Evolution.

Foy SG, Wilson BA, Bertram J, Cordes MHJ, Masel J.

Genetics. 2019 Apr;211(4):1345-1355. doi: 10.1534/genetics.118.301719. Epub 2019 Jan 28.


Does prior dengue virus exposure worsen clinical outcomes of Zika virus infection? A systematic review, pooled analysis and lessons learned.

Masel J, McCracken MK, Gleeson T, Morrison B, Rutherford G, Imrie A, Jarman RG, Koren M, Pollett S.

PLoS Negl Trop Dis. 2019 Jan 25;13(1):e0007060. doi: 10.1371/journal.pntd.0007060. eCollection 2019 Jan.


Density-dependent selection and the limits of relative fitness.

Bertram J, Masel J.

Theor Popul Biol. 2019 Oct;129:81-92. doi: 10.1016/j.tpb.2018.11.006. Epub 2019 Jan 18.


Directional Selection Rather Than Functional Constraints Can Shape the G Matrix in Rapidly Adapting Asexuals.

Gomez K, Bertram J, Masel J.

Genetics. 2019 Feb;211(2):715-729. doi: 10.1534/genetics.118.301685. Epub 2018 Dec 17.


Evolutionary Capacitance Emerges Spontaneously during Adaptation to Environmental Changes.

Nelson P, Masel J.

Cell Rep. 2018 Oct 2;25(1):249-258. doi: 10.1016/j.celrep.2018.09.008.


Gene Birth Contributes to Structural Disorder Encoded by Overlapping Genes.

Willis S, Masel J.

Genetics. 2018 Sep;210(1):303-313. doi: 10.1534/genetics.118.301249. Epub 2018 Jul 19.


Reply to Cheong et al.: Unicellular survival precludes Parrondo's paradox.

Nelson P, Masel J.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5260. doi: 10.1073/pnas.1806709115. Epub 2018 May 11. No abstract available.


Reply to Mitteldorf and Fahy: Aging is still inevitable.

Nelson P, Masel J.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E559. doi: 10.1073/pnas.1720890115. Epub 2018 Jan 8. No abstract available.


Contextual factors and clinical reasoning: differences in diagnostic and therapeutic reasoning in board certified versus resident physicians.

McBee E, Ratcliffe T, Picho K, Schuwirth L, Artino AR Jr, Yepes-Rios AM, Masel J, van der Vleuten C, Durning SJ.

BMC Med Educ. 2017 Nov 15;17(1):211. doi: 10.1186/s12909-017-1041-x.


Intercellular competition and the inevitability of multicellular aging.

Nelson P, Masel J.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):12982-12987. doi: 10.1073/pnas.1618854114. Epub 2017 Oct 30.


Foldability of a Natural De Novo Evolved Protein.

Bungard D, Copple JS, Yan J, Chhun JJ, Kumirov VK, Foy SG, Masel J, Wysocki VH, Cordes MHJ.

Structure. 2017 Nov 7;25(11):1687-1696.e4. doi: 10.1016/j.str.2017.09.006. Epub 2017 Oct 12.


Guidelines for the prevention of travel-associated illness in older adults.

Lee TK, Hutter JN, Masel J, Joya C, Whitman TJ.

Trop Dis Travel Med Vaccines. 2017 Jun 13;3:10. doi: 10.1186/s40794-017-0054-0. eCollection 2017. Review.


Young Genes are Highly Disordered as Predicted by the Preadaptation Hypothesis of De Novo Gene Birth.

Wilson BA, Foy SG, Neme R, Masel J.

Nat Ecol Evol. 2017 Jun;1(6):0146-146. doi: 10.1038/s41559-017-0146. Epub 2017 Apr 24.


The Association between Sexually Transmitted Infections, Length of Service and Other Demographic Factors in the U.S. Military.

Deiss R, Bower RJ, Co E, Mesner O, Sanchez JL, Masel J, Ganesan A, Macalino GE, Agan BK.

PLoS One. 2016 Dec 9;11(12):e0167892. doi: 10.1371/journal.pone.0167892. eCollection 2016.


Predicting patterns of long-term adaptation and extinction with population genetics.

Bertram J, Gomez K, Masel J.

Evolution. 2017 Feb;71(2):204-214. doi: 10.1111/evo.13116. Epub 2016 Dec 9.


Drift Barriers to Quality Control When Genes Are Expressed at Different Levels.

Xiong K, McEntee JP, Porfirio DJ, Masel J.

Genetics. 2017 Jan;205(1):397-407. doi: 10.1534/genetics.116.192567. Epub 2016 Nov 11.


Nodular Skin Lesions in an Immunocompromised Patient.

Masel JH, Martell DW, Logemann NF, Wilson KE.

Clin Infect Dis. 2016 Oct 15;63(8):1140-1. doi: 10.1093/cid/ciw434. No abstract available.


Answering evolutionary questions: A guide for mechanistic biologists.

Masel J, Promislow DE.

Bioessays. 2016 Jul;38(7):704-11. doi: 10.1002/bies.201600029. Epub 2016 May 6. Review.


Transurethral Use of Evicel(®) Fibrin Sealant.

Masel JL.

Urol Case Rep. 2015 Nov 27;4:5-7. doi: 10.1016/j.eucr.2015.10.006. eCollection 2016 Jan.


Clinical Reasoning Tasks and Resident Physicians: What Do They Reason About?

McBee E, Ratcliffe T, Goldszmidt M, Schuwirth L, Picho K, Artino AR Jr, Masel J, Durning SJ.

Acad Med. 2016 Jul;91(7):1022-8. doi: 10.1097/ACM.0000000000001024.


Evidence-Based Medicine as a Tool for Undergraduate Probability and Statistics Education.

Masel J, Humphrey PT, Blackburn B, Levine JA.

CBE Life Sci Educ. 2015 Winter;14(4):ar42. doi: 10.1187/cbe.15-04-0079.


What Fraction of Duplicates Observed in Recently Sequenced Genomes Is Segregating and Destined to Fail to Fix?

Teufel AI, Masel J, Liberles DA.

Genome Biol Evol. 2015 Jul 27;7(8):2258-64. doi: 10.1093/gbe/evv139.


The Recent De Novo Origin of Protein C-Termini.

Andreatta ME, Levine JA, Foy SG, Guzman LD, Kosinski LJ, Cordes MH, Masel J.

Genome Biol Evol. 2015 May 21;7(6):1686-701. doi: 10.1093/gbe/evv098.


Seroprevalence and seroincidence of herpes simplex virus (2006-2010), syphilis (2006-2010), and vaccine-preventable human papillomavirus subtypes (2000-2010) among US military personnel.

Masel J, Deiss RG, Wang X, Sanchez JL, Ganesan A, Macalino GE, Gaydos JC, Kortepeter MG, Agan BK.

Sex Transm Dis. 2015 May;42(5):253-8. doi: 10.1097/OLQ.0000000000000277.


Consequences of contextual factors on clinical reasoning in resident physicians.

McBee E, Ratcliffe T, Picho K, Artino AR Jr, Schuwirth L, Kelly W, Masel J, van der Vleuten C, Durning SJ.

Adv Health Sci Educ Theory Pract. 2015 Dec;20(5):1225-36. doi: 10.1007/s10459-015-9597-x. Epub 2015 Mar 10.


Constraints on the evolution of phenotypic plasticity: limits and costs of phenotype and plasticity.

Murren CJ, Auld JR, Callahan H, Ghalambor CK, Handelsman CA, Heskel MA, Kingsolver JG, Maclean HJ, Masel J, Maughan H, Pfennig DW, Relyea RA, Seiter S, Snell-Rood E, Steiner UK, Schlichting CD.

Heredity (Edinb). 2015 Oct;115(4):293-301. doi: 10.1038/hdy.2015.8. Epub 2015 Feb 18. Review.


Cryptic genetic variation can make "irreducible complexity" a common mode of adaptation in sexual populations.

Trotter MV, Weissman DB, Peterson GI, Peck KM, Masel J.

Evolution. 2014 Dec;68(12):3357-67. doi: 10.1111/evo.12517. Epub 2014 Sep 29.


Campylobacter fetus bacteremia in an immunocompetent traveler.

Mikals K, Masel J, Gleeson T.

Am J Trop Med Hyg. 2014 Oct;91(4):766. doi: 10.4269/ajtmh.14-0085. Epub 2014 Jul 28.


Chance, purpose, and progress in evolution and christianity.

Mix LJ, Masel J.

Evolution. 2014 Aug;68(8):2441-51. doi: 10.1111/evo.12434. Epub 2014 May 22.


Q&A: Evolutionary capacitance.

Masel J.

BMC Biol. 2013 Sep 30;11:103. doi: 10.1186/1741-7007-11-103. No abstract available.


Compensatory evolution and the origins of innovations.

Rajon E, Masel J.

Genetics. 2013 Apr;193(4):1209-20. doi: 10.1534/genetics.112.148627. Epub 2013 Jan 18.


Rethinking Hardy-Weinberg and genetic drift in undergraduate biology.

Masel J.

Bioessays. 2012 Aug;34(8):701-10. doi: 10.1002/bies.201100178. Epub 2012 May 10.


Hsp90 depletion goes wild.

Siegal ML, Masel J.

BMC Biol. 2012 Feb 27;10:14. doi: 10.1186/1741-7007-10-14.


Genetic drift.

Masel J.

Curr Biol. 2011 Oct 25;21(20):R837-8. doi: 10.1016/j.cub.2011.08.007. Review. No abstract available.


Putatively noncoding transcripts show extensive association with ribosomes.

Wilson BA, Masel J.

Genome Biol Evol. 2011;3:1245-52. doi: 10.1093/gbe/evr099. Epub 2011 Sep 26.


The consequences of rare sexual reproduction by means of selfing in an otherwise clonally reproducing species.

Masel J, Lyttle DN.

Theor Popul Biol. 2011 Dec;80(4):317-22. doi: 10.1016/j.tpb.2011.08.004. Epub 2011 Aug 24.


Evolution of molecular error rates and the consequences for evolvability.

Rajon E, Masel J.

Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1082-7. doi: 10.1073/pnas.1012918108. Epub 2011 Jan 3.


Bronchoarterial ratio on high-resolution CT scan of the chest in children without pulmonary pathology: need to redefine bronchial dilatation.

Kapur N, Masel JP, Watson D, Masters IB, Chang AB.

Chest. 2011 Jun;139(6):1445-1450. doi: 10.1378/chest.10-1763. Epub 2010 Sep 23.


Robustness and evolvability.

Masel J, Trotter MV.

Trends Genet. 2010 Sep;26(9):406-14. doi: 10.1016/j.tig.2010.06.002. Epub 2010 Jul 1. Review.


The spontaneous appearance rate of the yeast prion [PSI+] and its implications for the evolution of the evolvability properties of the [PSI+] system.

Lancaster AK, Bardill JP, True HL, Masel J.

Genetics. 2010 Feb;184(2):393-400. doi: 10.1534/genetics.109.110213. Epub 2009 Nov 16.


Robustness: mechanisms and consequences.

Masel J, Siegal ML.

Trends Genet. 2009 Sep;25(9):395-403. doi: 10.1016/j.tig.2009.07.005. Epub 2009 Aug 28. Review.


Quantitative prediction of molecular clock and ka/ks at short timescales.

Peterson GI, Masel J.

Mol Biol Evol. 2009 Nov;26(11):2595-603. doi: 10.1093/molbev/msp175. Epub 2009 Aug 6.


Complex adaptations can drive the evolution of the capacitor [PSI], even with realistic rates of yeast sex.

Griswold CK, Masel J.

PLoS Genet. 2009 Jun;5(6):e1000517. doi: 10.1371/journal.pgen.1000517. Epub 2009 Jun 12.


The evolution of reversible switches in the presence of irreversible mimics.

Lancaster AK, Masel J.

Evolution. 2009 Sep;63(9):2350-62. doi: 10.1111/j.1558-5646.2009.00729.x. Epub 2009 May 21.


The strength of selection against the yeast prion [PSI+].

Masel J, Griswold CK.

Genetics. 2009 Mar;181(3):1057-63. doi: 10.1534/genetics.108.100297. Epub 2009 Jan 19.


The evolution of bet-hedging adaptations to rare scenarios.

King OD, Masel J.

Theor Popul Biol. 2007 Dec;72(4):560-75. Epub 2007 Aug 31.

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