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Items: 1 to 50 of 69

1.

Ticagrelor with or without Aspirin in High-Risk Patients after PCI.

Mehran R, Baber U, Sharma SK, Cohen DJ, Angiolillo DJ, Briguori C, Cha JY, Collier T, Dangas G, Dudek D, Džavík V, Escaned J, Gil R, Gurbel P, Hamm CW, Henry T, Huber K, Kastrati A, Kaul U, Kornowski R, Krucoff M, Kunadian V, Marx SO, Mehta SR, Moliterno D, Ohman EM, Oldroyd K, Sardella G, Sartori S, Shlofmitz R, Steg PG, Weisz G, Witzenbichler B, Han YL, Pocock S, Gibson CM.

N Engl J Med. 2019 Nov 21;381(21):2032-2042. doi: 10.1056/NEJMoa1908419. Epub 2019 Sep 26.

PMID:
31556978
2.

Clinical Outcomes Before and After Complete Everolimus-Eluting Bioresorbable Scaffold Resorption: Five-Year Follow-Up From the ABSORB III Trial.

Kereiakes DJ, Ellis SG, Metzger DC, Caputo RP, Rizik DG, Teirstein PS, Litt MR, Kini A, Kabour A, Marx SO, Popma JJ, Tan SH, Ediebah DE, Simonton C, Stone GW; ABSORB III Investigators.

Circulation. 2019 Dec 3;140(23):1895-1903. doi: 10.1161/CIRCULATIONAHA.119.042584. Epub 2019 Sep 25.

PMID:
31553222
3.

Heterogeneity of the action potential duration is required for sustained atrial fibrillation.

Avula UMR, Abrams J, Katchman A, Zakharov S, Mironov S, Bayne J, Roybal D, Gorti A, Yang L, Iyer V, Waase M, Saluja D, Ciaccio EJ, Garan H, Marks AR, Marx SO, Wan EY.

JCI Insight. 2019 Apr 25;5. pii: 128765. doi: 10.1172/jci.insight.128765.

4.

Secretoneurin to the Rescue?

Morrow JP, Marx SO.

Circ Arrhythm Electrophysiol. 2019 Apr;12(4):e007298. doi: 10.1161/CIRCEP.119.007298. No abstract available.

PMID:
30943764
5.

Cardiac CaV1.2 channels require β subunits for β-adrenergic-mediated modulation but not trafficking.

Yang L, Katchman A, Kushner J, Kushnir A, Zakharov SI, Chen BX, Shuja Z, Subramanyam P, Liu G, Papa A, Roybal D, Pitt GS, Colecraft HM, Marx SO.

J Clin Invest. 2019 Feb 1;129(2):647-658. doi: 10.1172/JCI123878. Epub 2019 Jan 7.

6.

Transcatheter Mitral-Valve Repair in Patients with Heart Failure.

Stone GW, Lindenfeld J, Abraham WT, Kar S, Lim DS, Mishell JM, Whisenant B, Grayburn PA, Rinaldi M, Kapadia SR, Rajagopal V, Sarembock IJ, Brieke A, Marx SO, Cohen DJ, Weissman NJ, Mack MJ; COAPT Investigators.

N Engl J Med. 2018 Dec 13;379(24):2307-2318. doi: 10.1056/NEJMoa1806640. Epub 2018 Sep 23.

PMID:
30280640
7.

Blinded outcomes and angina assessment of coronary bioresorbable scaffolds: 30-day and 1-year results from the ABSORB IV randomised trial.

Stone GW, Ellis SG, Gori T, Metzger DC, Stein B, Erickson M, Torzewski J, Williams J Jr, Lawson W, Broderick TM, Kabour A, Piegari G, Cavendish J, Bertolet B, Choi JW, Marx SO, Généreux P, Kereiakes DJ; ABSORB IV Investigators.

Lancet. 2018 Oct 27;392(10157):1530-1540. doi: 10.1016/S0140-6736(18)32283-9. Epub 2018 Sep 25. Erratum in: Lancet. 2019 Oct 5;394(10205):1230.

PMID:
30266412
8.

3-Year Clinical Outcomes With Everolimus-Eluting Bioresorbable Coronary Scaffolds: The ABSORB III Trial.

Kereiakes DJ, Ellis SG, Metzger C, Caputo RP, Rizik DG, Teirstein PS, Litt MR, Kini A, Kabour A, Marx SO, Popma JJ, McGreevy R, Zhang Z, Simonton C, Stone GW; ABSORB III Investigators.

J Am Coll Cardiol. 2017 Dec 12;70(23):2852-2862. doi: 10.1016/j.jacc.2017.10.010. Epub 2017 Oct 31.

9.

Proteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart.

Katchman A, Yang L, Zakharov SI, Kushner J, Abrams J, Chen BX, Liu G, Pitt GS, Colecraft HM, Marx SO.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9194-9199. doi: 10.1073/pnas.1706054114. Epub 2017 Aug 7.

10.

Calmodulin limits pathogenic Na+ channel persistent current.

Yan H, Wang C, Marx SO, Pitt GS.

J Gen Physiol. 2017 Feb;149(2):277-293. doi: 10.1085/jgp.201611721. Epub 2017 Jan 13.

11.

Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice.

Wan E, Abrams J, Weinberg RL, Katchman AN, Bayne J, Zakharov SI, Yang L, Morrow JP, Garan H, Marx SO.

J Clin Invest. 2016 Jan;126(1):112-22. doi: 10.1172/JCI84669. Epub 2015 Nov 23.

12.

Everolimus-Eluting Bioresorbable Scaffolds for Coronary Artery Disease.

Ellis SG, Kereiakes DJ, Metzger DC, Caputo RP, Rizik DG, Teirstein PS, Litt MR, Kini A, Kabour A, Marx SO, Popma JJ, McGreevy R, Zhang Z, Simonton C, Stone GW; ABSORB III Investigators.

N Engl J Med. 2015 Nov 12;373(20):1905-15. doi: 10.1056/NEJMoa1509038. Epub 2015 Oct 12.

13.
14.

Positions of the cytoplasmic end of BK α S0 helix relative to S1-S6 and of β1 TM1 and TM2 relative to S0-S6.

Liu G, Zakharov SI, Yao Y, Marx SO, Karlin A.

J Gen Physiol. 2015 Mar;145(3):185-99. doi: 10.1085/jgp.201411337. Epub 2015 Feb 9.

15.

The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.

Yang L, Katchman A, Weinberg RL, Abrams J, Samad T, Wan E, Pitt GS, Marx SO.

J Biol Chem. 2015 Jan 23;290(4):2166-74. doi: 10.1074/jbc.M114.602508. Epub 2014 Dec 11.

16.

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.

Santulli G, Wronska A, Uryu K, Diacovo TG, Gao M, Marx SO, Kitajewski J, Chilton JM, Akat KM, Tuschl T, Marks AR, Totary-Jain H.

J Clin Invest. 2014 Sep;124(9):4102-14. doi: 10.1172/JCI76069. Epub 2014 Aug 18.

17.

Treatment of experimental asthma using a single small molecule with anti-inflammatory and BK channel-activating properties.

Goldklang MP, Perez-Zoghbi JF, Trischler J, Nkyimbeng T, Zakharov SI, Shiomi T, Zelonina T, Marks AR, D'Armiento JM, Marx SO.

FASEB J. 2013 Dec;27(12):4975-86. doi: 10.1096/fj.13-235176. Epub 2013 Aug 30.

18.

β-adrenergic regulation of the L-type Ca2+ channel does not require phosphorylation of α1C Ser1700.

Yang L, Katchman A, Samad T, Morrow J, Weinberg R, Marx SO.

Circ Res. 2013 Sep 13;113(7):871-80. doi: 10.1161/CIRCRESAHA.113.301926. Epub 2013 Jul 3.

19.

Dysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseases.

Marx SO, Marks AR.

J Mol Cell Cardiol. 2013 May;58:225-31. doi: 10.1016/j.yjmcc.2013.03.005. Epub 2013 Mar 16. Review.

20.

Orientations and proximities of the extracellular ends of transmembrane helices S0 and S4 in open and closed BK potassium channels.

Niu X, Liu G, Wu RS, Chudasama N, Zakharov SI, Karlin A, Marx SO.

PLoS One. 2013;8(3):e58335. doi: 10.1371/journal.pone.0058335. Epub 2013 Mar 5.

21.

Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice.

Wan E, Kushner JS, Zakharov S, Nui XW, Chudasama N, Kelly C, Waase M, Doshi D, Liu G, Iwata S, Shiomi T, Katchman A, D'Armiento J, Homma S, Marx SO.

FASEB J. 2013 May;27(5):1859-67. doi: 10.1096/fj.12-223511. Epub 2013 Jan 16.

22.

Reprogramming of the microRNA transcriptome mediates resistance to rapamycin.

Totary-Jain H, Sanoudou D, Ben-Dov IZ, Dautriche CN, Guarnieri P, Marx SO, Tuschl T, Marks AR.

J Biol Chem. 2013 Mar 1;288(9):6034-44. doi: 10.1074/jbc.M112.416446. Epub 2013 Jan 8.

23.

Positions of β2 and β3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel.

Wu RS, Liu G, Zakharov SI, Chudasama N, Motoike H, Karlin A, Marx SO.

J Gen Physiol. 2013 Jan;141(1):105-17. doi: 10.1085/jgp.201210891.

24.

Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1.

Chan PJ, Osteen JD, Xiong D, Bohnen MS, Doshi D, Sampson KJ, Marx SO, Karlin A, Kass RS.

J Gen Physiol. 2012 Feb;139(2):135-44. doi: 10.1085/jgp.201110672. Epub 2012 Jan 16.

25.

Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias.

Morrow JP, Katchman A, Son NH, Trent CM, Khan R, Shiomi T, Huang H, Amin V, Lader JM, Vasquez C, Morley GE, D'Armiento J, Homma S, Goldberg IJ, Marx SO.

Circulation. 2011 Dec 20;124(25):2812-21. doi: 10.1161/CIRCULATIONAHA.111.056309. Epub 2011 Nov 28.

26.

Vascular smooth muscle cell proliferation in restenosis.

Marx SO, Totary-Jain H, Marks AR.

Circ Cardiovasc Interv. 2011 Feb 1;4(1):104-11. doi: 10.1161/CIRCINTERVENTIONS.110.957332. Review. No abstract available.

27.

Cardiac L-type calcium channel (Cav1.2) associates with gamma subunits.

Yang L, Katchman A, Morrow JP, Doshi D, Marx SO.

FASEB J. 2011 Mar;25(3):928-36. doi: 10.1096/fj.10-172353. Epub 2010 Dec 2.

28.

The BK potassium channel in the vascular smooth muscle and kidney: α- and β-subunits.

Wu RS, Marx SO.

Kidney Int. 2010 Nov;78(10):963-74. doi: 10.1038/ki.2010.325. Epub 2010 Sep 22. Review.

29.

Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart.

Xu X, Marx SO, Colecraft HM.

Circ Res. 2010 Sep 3;107(5):620-30. doi: 10.1161/CIRCRESAHA.110.224717. Epub 2010 Jul 8.

30.

Location of modulatory beta subunits in BK potassium channels.

Liu G, Niu X, Wu RS, Chudasama N, Yao Y, Jin X, Weinberg R, Zakharov SI, Motoike H, Marx SO, Karlin A.

J Gen Physiol. 2010 May;135(5):449-59. doi: 10.1085/jgp.201010417. Epub 2010 Apr 12.

31.

Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.

Moss SC, Lightell DJ Jr, Marx SO, Marks AR, Woods TC.

J Biol Chem. 2010 Apr 16;285(16):11991-7. doi: 10.1074/jbc.M109.066621. Epub 2010 Jan 22.

32.

Location of the beta 4 transmembrane helices in the BK potassium channel.

Wu RS, Chudasama N, Zakharov SI, Doshi D, Motoike H, Liu G, Yao Y, Niu X, Deng SX, Landry DW, Karlin A, Marx SO.

J Neurosci. 2009 Jul 1;29(26):8321-8. doi: 10.1523/JNEUROSCI.6191-08.2009.

33.

Protein kinase C isoforms differentially phosphorylate Ca(v)1.2 alpha(1c).

Yang L, Doshi D, Morrow J, Katchman A, Chen X, Marx SO.

Biochemistry. 2009 Jul 21;48(28):6674-83. doi: 10.1021/bi900322a. Erratum in: Biochemistry. 2009 Sep 15;48(36):8764.

34.

Ion channels, transporters, and pumps as targets for heart failure therapy.

Doshi D, Marx SO.

J Cardiovasc Pharmacol. 2009 Oct;54(4):273-8. doi: 10.1097/FJC.0b013e3181a1b9c7. Review.

35.

Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines.

Chung DY, Chan PJ, Bankston JR, Yang L, Liu G, Marx SO, Karlin A, Kass RS.

Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):743-8. doi: 10.1073/pnas.0811897106. Epub 2009 Jan 8.

36.

Leptin-enhanced neointimal hyperplasia is reduced by mTOR and PI3K inhibitors.

Shan J, Nguyen TB, Totary-Jain H, Dansky H, Marx SO, Marks AR.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):19006-11. doi: 10.1073/pnas.0809743105. Epub 2008 Nov 19.

37.

Locations of the beta1 transmembrane helices in the BK potassium channel.

Liu G, Zakharov SI, Yang L, Wu RS, Deng SX, Landry DW, Karlin A, Marx SO.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10727-32. doi: 10.1073/pnas.0805212105. Epub 2008 Jul 31.

38.

Scaffolding proteins in cardiac myocytes.

Chudasama NL, Marx SO, Steinberg SF.

Handb Exp Pharmacol. 2008;(186):301-25. doi: 10.1007/978-3-540-72843-6_13. Review.

PMID:
18491058
39.

Position and role of the BK channel alpha subunit S0 helix inferred from disulfide crosslinking.

Liu G, Zakharov SI, Yang L, Deng SX, Landry DW, Karlin A, Marx SO.

J Gen Physiol. 2008 Jun;131(6):537-48. doi: 10.1085/jgp.200809968. Epub 2008 May 12.

40.

Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits.

Yang L, Liu G, Zakharov SI, Bellinger AM, Mongillo M, Marx SO.

Circ Res. 2007 Aug 31;101(5):465-74. Epub 2007 Jul 12.

PMID:
17626895
41.

AKAPs as antiarrhythmic targets?

Marx SO, Kurokawa J.

Handb Exp Pharmacol. 2006;(171):221-33. Review.

PMID:
16610346
42.

Defining the BK channel domains required for beta1-subunit modulation.

Morrow JP, Zakharov SI, Liu G, Yang L, Sok AJ, Marx SO.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5096-101. Epub 2006 Mar 20.

43.

Activation of the BK (SLO1) potassium channel by mallotoxin.

Zakharov SI, Morrow JP, Liu G, Yang L, Marx SO.

J Biol Chem. 2005 Sep 2;280(35):30882-7. Epub 2005 Jul 5.

44.

Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms.

Yang L, Liu G, Zakharov SI, Morrow JP, Rybin VO, Steinberg SF, Marx SO.

J Biol Chem. 2005 Jan 7;280(1):207-14. Epub 2004 Oct 27.

45.

Direct interaction between BKCa potassium channel and microtubule-associated protein 1A.

Park SM, Liu G, Kubal A, Fury M, Cao L, Marx SO.

FEBS Lett. 2004 Jul 16;570(1-3):143-8.

46.

Assembly of a Ca2+-dependent BK channel signaling complex by binding to beta2 adrenergic receptor.

Liu G, Shi J, Yang L, Cao L, Park SM, Cui J, Marx SO.

EMBO J. 2004 Jun 2;23(11):2196-205. Epub 2004 May 13.

47.

Immunophilins and coupled gating of ryanodine receptors.

Lehnart SE, Huang F, Marx SO, Marks AR.

Curr Top Med Chem. 2003;3(12):1383-91. Review.

PMID:
12871170
48.

Leucine/isoleucine zipper coordination of ion channel macromolecular signaling complexes in the heart. Roles in inherited arrhythmias.

Kass RS, Kurokawa J, Marx SO, Marks AR.

Trends Cardiovasc Med. 2003 Feb;13(2):52-6. Review.

PMID:
12586439
49.

Regulation of the ryanodine receptor in heart failure.

Marx SO, Marks AR.

Basic Res Cardiol. 2002;97 Suppl 1:I49-51. Review.

PMID:
12479234
50.

Regulation of ryanodine receptors via macromolecular complexes: a novel role for leucine/isoleucine zippers.

Marks AR, Marx SO, Reiken S.

Trends Cardiovasc Med. 2002 May;12(4):166-70. Review.

PMID:
12069756

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