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Items: 47


Persistence rate of cervical human papillomavirus infections and abnormal cytology in Rwanda.

Mukanyangezi MF, Rugwizangoga B, Manzi O, Rulisa S, Hellstrand K, Tobin G, Martner A, Bienvenu E, Giglio D.

HIV Med. 2019 Aug;20(7):485-495. doi: 10.1111/hiv.12782.


Immunotherapy with HDC/IL-2 may be clinically efficacious in acute myeloid leukemia of normal karyotype.

Nilsson MS, Hallner A, Brune M, Nilsson S, Thorén FB, Martner A, Hellstrand K.

Hum Vaccin Immunother. 2019 Jul 24:1-3. doi: 10.1080/21645515.2019.1636598. [Epub ahead of print]


Anthracycline-based consolidation may determine outcome of post-consolidation immunotherapy in AML.

Aurelius J, Möllgård L, Kiffin R, Ewald Sander F, Nilsson S, Bergh Thorén F, Hellstrand K, Martner A.

Leuk Lymphoma. 2019 Apr 17:1-8. doi: 10.1080/10428194.2019.1599110. [Epub ahead of print]


JAK-STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma.

Dolatabadi S, Jonasson E, Lindén M, Fereydouni B, Bäcksten K, Nilsson M, Martner A, Forootan A, Fagman H, Landberg G, Åman P, Ståhlberg A.

Int J Cancer. 2019 Jul 15;145(2):435-449. doi: 10.1002/ijc.32123. Epub 2019 Jan 29.


The HLA-B -21 dimorphism impacts on NK cell education and clinical outcome of immunotherapy in acute myeloid leukemia.

Hallner A, Bernson E, Hussein BA, Ewald Sander F, Brune M, Aurelius J, Martner A, Hellstrand K, Thorén FB.

Blood. 2019 Mar 28;133(13):1479-1488. doi: 10.1182/blood-2018-09-874990. Epub 2019 Jan 15.


Isolated Limb Perfusion With Melphalan Triggers Immune Activation in Melanoma Patients.

Johansson J, Kiffin R, Andersson A, Lindnér P, Naredi PL, Olofsson Bagge R, Martner A.

Front Oncol. 2018 Dec 3;8:570. doi: 10.3389/fonc.2018.00570. eCollection 2018.


NOX2 inhibition reduces oxidative stress and prolongs survival in murine KRAS-induced myeloproliferative disease.

Aydin E, Hallner A, Grauers Wiktorin H, Staffas A, Hellstrand K, Martner A.

Oncogene. 2019 Feb;38(9):1534-1543. doi: 10.1038/s41388-018-0528-1. Epub 2018 Oct 15.


Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade.

Grauers Wiktorin H, Nilsson MS, Kiffin R, Sander FE, Lenox B, Rydström A, Hellstrand K, Martner A.

Cancer Immunol Immunother. 2019 Feb;68(2):163-174. doi: 10.1007/s00262-018-2253-6. Epub 2018 Oct 12.


NOX2 in autoimmunity, tumor growth and metastasis.

Martner A, Aydin E, Hellstrand K.

J Pathol. 2019 Feb;247(2):151-154. doi: 10.1002/path.5175. Epub 2018 Nov 29.


Cytomegalovirus Serostatus Affects Autoreactive NK Cells and Outcomes of IL2-Based Immunotherapy in Acute Myeloid Leukemia.

Bernson E, Hallner A, Sander FE, Nicklasson M, Nilsson MS, Christenson K, Aydin E, Liljeqvist JÅ, Brune M, Foà R, Aurelius J, Martner A, Hellstrand K, Thorén FB.

Cancer Immunol Res. 2018 Sep;6(9):1110-1119. doi: 10.1158/2326-6066.CIR-17-0711. Epub 2018 Jul 6.


Anti-Leukemic Properties of Histamine in Monocytic Leukemia: The Role of NOX2.

Kiffin R, Grauers Wiktorin H, Nilsson MS, Aurelius J, Aydin E, Lenox B, Nilsson JA, Ståhlberg A, Thorén FB, Hellstrand K, Martner A.

Front Oncol. 2018 Jun 18;8:218. doi: 10.3389/fonc.2018.00218. eCollection 2018.


Redox control of cancer cell destruction.

Hegedűs C, Kovács K, Polgár Z, Regdon Z, Szabó É, Robaszkiewicz A, Forman HJ, Martner A, Virág L.

Redox Biol. 2018 Jun;16:59-74. doi: 10.1016/j.redox.2018.01.015. Epub 2018 Feb 3. Review.


Role of NOX2-Derived Reactive Oxygen Species in NK Cell-Mediated Control of Murine Melanoma Metastasis.

Aydin E, Johansson J, Nazir FH, Hellstrand K, Martner A.

Cancer Immunol Res. 2017 Sep;5(9):804-811. doi: 10.1158/2326-6066.CIR-16-0382. Epub 2017 Jul 31.


Role of regulatory T cells in acute myeloid leukemia patients undergoing relapse-preventive immunotherapy.

Sander FE, Nilsson M, Rydström A, Aurelius J, Riise RE, Movitz C, Bernson E, Kiffin R, Ståhlberg A, Brune M, Foà R, Hellstrand K, Thorén FB, Martner A.

Cancer Immunol Immunother. 2017 Nov;66(11):1473-1484. doi: 10.1007/s00262-017-2040-9. Epub 2017 Jul 18.


Role of NOX2 for leukaemic expansion in a murine model of BCR-ABL1+ leukaemia.

Grauers Wiktorin H, Nilsson T, Aydin E, Hellstrand K, Palmqvist L, Martner A.

Br J Haematol. 2018 Jul;182(2):290-294. doi: 10.1111/bjh.14772. Epub 2017 May 23. No abstract available.


Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia.

Bernson E, Hallner A, Sander FE, Wilsson O, Werlenius O, Rydström A, Kiffin R, Brune M, Foà R, Aurelius J, Martner A, Hellstrand K, Thorén FB.

Leukemia. 2017 Dec;31(12):2552-2559. doi: 10.1038/leu.2017.151. Epub 2017 May 22.


NOX2-dependent immunosuppression in chronic myelomonocytic leukemia.

Aurelius J, Hallner A, Werlenius O, Riise R, Möllgård L, Brune M, Hansson M, Martner A, Thorén FB, Hellstrand K.

J Leukoc Biol. 2017 Aug;102(2):459-466. doi: 10.1189/jlb.5VMA1116-454R. Epub 2017 Mar 14.


Dynamics of myeloid cell populations during relapse-preventive immunotherapy in acute myeloid leukemia.

Rydström A, Hallner A, Aurelius J, Sander FE, Bernson E, Kiffin R, Thoren FB, Hellstrand K, Martner A.

J Leukoc Biol. 2017 Aug;102(2):467-474. doi: 10.1189/jlb.5VMA1116-455R. Epub 2017 Feb 24.


Intact Pneumococci Trigger Transcription of Interferon-Related Genes in Human Monocytes, while Fragmented, Autolyzed Bacteria Subvert This Response.

Skovbjerg S, Nordén R, Martner A, Samuelsson E, Hynsjö L, Wold AE.

Infect Immun. 2017 Apr 21;85(5). pii: e00960-16. doi: 10.1128/IAI.00960-16. Print 2017 May.


Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells.

Werlenius O, Aurelius J, Hallner A, Akhiani AA, Simpanen M, Martner A, Andersson PO, Hellstrand K, Thorén FB.

Oncotarget. 2016 May 31;7(22):32046-53. doi: 10.18632/oncotarget.8769.


Role of natural killer cell subsets and natural cytotoxicity receptors for the outcome of immunotherapy in acute myeloid leukemia.

Martner A, Rydström A, Riise RE, Aurelius J, Anderson H, Brune M, Foà R, Hellstrand K, Thorén FB.

Oncoimmunology. 2015 May 5;5(1):e1041701. doi: 10.1080/2162402X.2015.1041701. eCollection 2016.


Dynamics of cytotoxic T cell subsets during immunotherapy predicts outcome in acute myeloid leukemia.

Sander FE, Rydström A, Bernson E, Kiffin R, Riise R, Aurelius J, Anderson H, Brune M, Foà R, Hellstrand K, Thorén FB, Martner A.

Oncotarget. 2016 Feb 16;7(7):7586-96. doi: 10.18632/oncotarget.7210.


Melphalan, Antimelanoma Immunity, and Inflammation--Letter.

Martner A, Johansson J, Ben-Shabat I, Bagge RO.

Cancer Res. 2015 Dec 15;75(24):5398-9. doi: 10.1158/0008-5472.CAN-15-1184. Epub 2015 Dec 1. No abstract available.


NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance.

Martner A, Rydström A, Riise RE, Aurelius J, Brune M, Foà R, Hellstrand K, Thorén FB.

Oncotarget. 2015 Dec 15;6(40):42569-74. doi: 10.18632/oncotarget.5559.


TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses.

Riise RE, Bernson E, Aurelius J, Martner A, Pesce S, Della Chiesa M, Marcenaro E, Bylund J, Hellstrand K, Moretta L, Moretta A, Thorén FB.

J Immunol. 2015 Aug 1;195(3):1121-8. doi: 10.4049/jimmunol.1500709. Epub 2015 Jun 17.


Histamine promotes the development of monocyte-derived dendritic cells and reduces tumor growth by targeting the myeloid NADPH oxidase.

Martner A, Wiktorin HG, Lenox B, Ewald Sander F, Aydin E, Aurelius J, Thorén FB, Ståhlberg A, Hermodsson S, Hellstrand K.

J Immunol. 2015 May 15;194(10):5014-21. doi: 10.4049/jimmunol.1402991. Epub 2015 Apr 13.


Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells.

Ortiz ML, Kumar V, Martner A, Mony S, Donthireddy L, Condamine T, Seykora J, Knight SC, Malietzis G, Lee GH, Moorghen M, Lenox B, Luetteke N, Celis E, Gabrilovich D.

J Exp Med. 2015 Mar 9;212(3):351-67. doi: 10.1084/jem.20140835. Epub 2015 Feb 9.


Mutated NPM1 in combination with overexpression of Meis1 or Hoxa9 is not sufficient to induce acute myeloid leukemia.

Wiktorin HG, Nilsson T, Jansson A, Palmqvist L, Martner A.

Exp Hematol Oncol. 2016 Aug 11;5:25. doi: 10.1186/s40164-016-0053-2. eCollection 2015.


Immunotherapy with histamine dihydrochloride and low-dose interleukin-2 favors sustained lymphocyte recovery in acute myeloid leukemia.

Hallner A, Aurelius J, Thorén FB, Sander FE, Brune M, Hellstrand K, Martner A.

Eur J Haematol. 2015 Mar;94(3):279-80. doi: 10.1111/ejh.12454. Epub 2014 Nov 21. No abstract available. Erratum in: Eur J Haematol. 2019 Jan;102(1):99.


Reply: To PMID 24519039.

Lagging M, Rembeck K, Waldenström J, Nilsson S, Nyström K, Martner A, Lindh M, Norkrans G, Westin J, Pedersen C, Färkkilä M, Langeland N, Buhl MR, Mørch K, Christensen PB, Hellstrand K.

Hepatology. 2014 Dec;60(6):2130-1. doi: 10.1002/hep.27108. Epub 2014 Sep 24. No abstract available.


Role of the ERK pathway for oxidant-induced parthanatos in human lymphocytes.

Akhiani AA, Werlenius O, Aurelius J, Movitz C, Martner A, Hellstrand K, Thorén FB.

PLoS One. 2014 Feb 21;9(2):e89646. doi: 10.1371/journal.pone.0089646. eCollection 2014.


Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.

Rembeck K, Waldenström J, Hellstrand K, Nilsson S, Nyström K, Martner A, Lindh M, Norkrans G, Westin J, Pedersen C, Färkkilä M, Langeland N, Buhl MR, Mørch K, Christensen PB, Lagging M.

Hepatology. 2014 Jun;59(6):2131-9. doi: 10.1002/hep.27009. Epub 2014 Apr 25.


Valganciclovir in patients with glioblastoma.

Hellstrand K, Martner A, Bergström T.

N Engl J Med. 2013 Nov 21;369(21):2066. doi: 10.1056/NEJMc1312413. No abstract available.


Immunotherapeutic strategies for relapse control in acute myeloid leukemia.

Martner A, Thorén FB, Aurelius J, Hellstrand K.

Blood Rev. 2013 Sep;27(5):209-16. doi: 10.1016/j.blre.2013.06.006. Epub 2013 Jul 18. Review.


Stronger T cell immunogenicity of ovalbumin expressed intracellularly in Gram-negative than in Gram-positive bacteria.

Martner A, Ostman S, Lundin S, Rask C, Björnsson V, Telemo E, Collins LV, Axelsson L, Wold AE.

PLoS One. 2013 May 31;8(5):e65124. doi: 10.1371/journal.pone.0065124. Print 2013.


Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow.

Ramachandran IR, Martner A, Pisklakova A, Condamine T, Chase T, Vogl T, Roth J, Gabrilovich D, Nefedova Y.

J Immunol. 2013 Apr 1;190(7):3815-23. doi: 10.4049/jimmunol.1203373. Epub 2013 Mar 4.


Chronic myeloid leukemic cells trigger poly(ADP-ribose) polymerase-dependent inactivation and cell death in lymphocytes.

Aurelius J, Martner A, Riise RE, Romero AI, Palmqvist L, Brune M, Hellstrand K, Thorén FB.

J Leukoc Biol. 2013 Jan;93(1):155-60. doi: 10.1189/jlb.0512257. Epub 2012 Oct 16.


Remission maintenance in acute myeloid leukemia: impact of functional histamine H2 receptors expressed by leukemic cells.

Aurelius J, Martner A, Brune M, Palmqvist L, Hansson M, Hellstrand K, Thoren FB.

Haematologica. 2012 Dec;97(12):1904-8. doi: 10.3324/haematol.2012.066399. Epub 2012 Jun 11.


Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis.

Aurelius J, Thorén FB, Akhiani AA, Brune M, Palmqvist L, Hansson M, Hellstrand K, Martner A.

Blood. 2012 Jun 14;119(24):5832-7. doi: 10.1182/blood-2011-11-391722. Epub 2012 May 1.


Redox remodeling by dendritic cells protects antigen-specific T cells against oxidative stress.

Martner A, Aurelius J, Rydström A, Hellstrand K, Thorén FB.

J Immunol. 2011 Dec 15;187(12):6243-8. doi: 10.4049/jimmunol.1102138. Epub 2011 Nov 16.


Antitumor properties of histamine in vivo.

Thoren FB, Aurelius J, Martner A.

Nat Med. 2011 May;17(5):537; author reply 537-8. doi: 10.1038/nm0511-537a. No abstract available.


Immunotherapy with histamine dihydrochloride for the prevention of relapse in acute myeloid leukemia.

Martner A, Thorén FB, Aurelius J, Söderholm J, Brune M, Hellstrand K.

Expert Rev Hematol. 2010 Aug;3(4):381-91. doi: 10.1586/ehm.10.30. Review.


Gram-positive and gram-negative bacteria induce different patterns of cytokine production in human mononuclear cells irrespective of taxonomic relatedness.

Skovbjerg S, Martner A, Hynsjö L, Hessle C, Olsen I, Dewhirst FE, Tham W, Wold AE.

J Interferon Cytokine Res. 2010 Jan;30(1):23-32. doi: 10.1089/jir.2009.0033.


Streptococcus pneumoniae autolysis prevents phagocytosis and production of phagocyte-activating cytokines.

Martner A, Skovbjerg S, Paton JC, Wold AE.

Infect Immun. 2009 Sep;77(9):3826-37. doi: 10.1128/IAI.00290-09. Epub 2009 Jun 15.


Soluble bacterial constituents down-regulate secretion of IL-12 in response to intact Gram-positive bacteria.

Barkman C, Martner A, Hessle C, Wold AE.

Microbes Infect. 2008 Nov-Dec;10(14-15):1484-93. doi: 10.1016/j.micinf.2008.08.011. Epub 2008 Sep 12.


Pneumolysin released during Streptococcus pneumoniae autolysis is a potent activator of intracellular oxygen radical production in neutrophils.

Martner A, Dahlgren C, Paton JC, Wold AE.

Infect Immun. 2008 Sep;76(9):4079-87. doi: 10.1128/IAI.01747-07. Epub 2008 Jun 16.


Transfer of an ampicillin resistance gene between two Escherichia coli strains in the bowel microbiota of an infant treated with antibiotics.

Karami N, Martner A, Enne VI, Swerkersson S, Adlerberth I, Wold AE.

J Antimicrob Chemother. 2007 Nov;60(5):1142-5. Epub 2007 Sep 3.


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