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Items: 1 to 50 of 72


Life-threatening bronchiolitis related to electronic cigarette use in a Canadian youth.

Landman ST, Dhaliwal I, Mackenzie CA, Martinu T, Steele A, Bosma KJ.

CMAJ. 2019 Dec 2;191(48):E1321-E1331. doi: 10.1503/cmaj.191402. Epub 2019 Nov 20.


DNAse to the Rescue! Clearing Mitochondrial DNA May Have NET Benefits in Lung Transplantation.

Juvet S, Martinu T.

Am J Respir Cell Mol Biol. 2019 Nov 14. doi: 10.1165/rcmb.2019-0390ED. [Epub ahead of print] No abstract available.


Microbiota analysis optimization for human bronchoalveolar lavage fluid.

Schneeberger PHH, Prescod J, Levy L, Hwang D, Martinu T, Coburn B.

Microbiome. 2019 Oct 29;7(1):141. doi: 10.1186/s40168-019-0755-x.


IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease.

Martinu T, McManigle WC, Kelly FL, Nelson ME, Sun J, Zhang HL, Kolls JK, Gowdy KM, Palmer SM.

Transplantation. 2019 Nov;103(11):2264-2274. doi: 10.1097/TP.0000000000002837.


Prevention of viral transmission during lung transplantation with hepatitis C-viraemic donors: an open-label, single-centre, pilot trial.

Cypel M, Feld JJ, Galasso M, Pinto Ribeiro RV, Marks N, Kuczynski M, Kumar D, Bahinskaya I, Bagnato VS, Kurachi C, Slutsky AS, Yeung JC, Donahoe L, de Perrot M, Yasufuku K, Pierre A, Binnie M, Chaparro C, Martinu T, Chen M, Tikkanen J, Chow CW, Sidhu A, Waddell TK, Keshavjee S, Singer LG, Humar A.

Lancet Respir Med. 2020 Feb;8(2):192-201. doi: 10.1016/S2213-2600(19)30268-1. Epub 2019 Oct 9.


Long-term Outcomes of Lung Transplant With Ex Vivo Lung Perfusion.

Divithotawela C, Cypel M, Martinu T, Singer LG, Binnie M, Chow CW, Chaparro C, Waddell TK, de Perrot M, Pierre A, Yasufuku K, Yeung JC, Donahoe L, Keshavjee S, Tikkanen JM.

JAMA Surg. 2019 Oct 9. doi: 10.1001/jamasurg.2019.4079. [Epub ahead of print]


Drug-resistant cytomegalovirus infection after lung transplantation: Incidence, characteristics, and clinical outcomes.

Heliövaara E, Husain S, Martinu T, Singer LG, Cypel M, Humar A, Keshavjee S, Tikkanen J.

J Heart Lung Transplant. 2019 Dec;38(12):1268-1274. doi: 10.1016/j.healun.2019.09.005. Epub 2019 Sep 10.


Mesenchymal stromal cell therapy during ex vivo lung perfusion ameliorates ischemia-reperfusion injury in lung transplantation.

Nakajima D, Watanabe Y, Ohsumi A, Pipkin M, Chen M, Mordant P, Kanou T, Saito T, Lam R, Coutinho R, Caldarone L, Juvet S, Martinu T, Iyer RK, Davies JE, Hwang DM, Waddell TK, Cypel M, Liu M, Keshavjee S.

J Heart Lung Transplant. 2019 Nov;38(11):1214-1223. doi: 10.1016/j.healun.2019.07.006. Epub 2019 Jul 26.


The impact of first untreated subclinical minimal acute rejection on risk for chronic lung allograft dysfunction or death after lung transplantation.

Levy L, Huszti E, Tikkanen J, Ghany R, Klement W, Ahmed M, Husain S, Fiset PO, Hwang D, Keshavjee S, Singer LG, Juvet S, Martinu T.

Am J Transplant. 2020 Jan;20(1):241-249. doi: 10.1111/ajt.15561. Epub 2019 Sep 6.


A B cell-dependent pathway drives chronic lung allograft rejection after ischemia-reperfusion injury in mice.

Watanabe T, Martinu T, Chruscinski A, Boonstra K, Joe B, Horie M, Guan Z, Bei KF, Hwang DM, Liu M, Keshavjee S, Juvet SC.

Am J Transplant. 2019 Dec;19(12):3377-3389. doi: 10.1111/ajt.15550. Epub 2019 Aug 26.


Lung Density Analysis Using Quantitative Chest CT for Early Prediction of Chronic Lung Allograft Dysfunction.

Horie M, Levy L, Houbois C, Salazar P, Saito T, Pakkal M, OʼBrien C, Sajja S, Brock K, Yasufuku K, Keshavjee S, Paul N, Martinu T.

Transplantation. 2019 Dec;103(12):2645-2653. doi: 10.1097/TP.0000000000002771.


Donor human leukocyte antigen-G single nucleotide polymorphisms are associated with post-lung transplant mortality.

Lazarte J, Ma J, Martinu T, Levy L, Klement W, White M, Pelling J, Guan Z, Azad S, Tikkanen J, Rao V, Tomlinson G, Delgado D, Keshavjee S, Juvet SC.

Eur Respir J. 2019 Aug 15;54(2). pii: 1802126. doi: 10.1183/13993003.02126-2018. Print 2019 Aug.


Epithelial cell death markers in bronchoalveolar lavage correlate with chronic lung allograft dysfunction subtypes and survival in lung transplant recipients-a single-center retrospective cohort study.

Levy L, Tigert A, Huszti E, Saito T, Mitsakakis N, Moshkelgosha S, Joe B, Boonstra KM, Tikkanen JM, Keshavjee S, Juvet SC, Martinu T.

Transpl Int. 2019 Sep;32(9):965-973. doi: 10.1111/tri.13444. Epub 2019 May 15.


Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment-A consensus report from the Pulmonary Council of the ISHLT.

Verleden GM, Glanville AR, Lease ED, Fisher AJ, Calabrese F, Corris PA, Ensor CR, Gottlieb J, Hachem RR, Lama V, Martinu T, Neil DAH, Singer LG, Snell G, Vos R.

J Heart Lung Transplant. 2019 May;38(5):493-503. doi: 10.1016/j.healun.2019.03.009. Epub 2019 Apr 3. No abstract available.


Cytokine profile in lung transplant recipients with Aspergillus spp colonization.

Herrera S, Gohir W, Foroutan F, Aguilar C, Juvet S, Martinu T, Kumar D, Humar A, Rotstein C, Keshavjee S, Singer LG, Husain S.

Transpl Infect Dis. 2019 Jun;21(3):e13060. doi: 10.1111/tid.13060. Epub 2019 Mar 21.


Lentiviral interleukin-10 gene therapy: Safety and questions.

Liu M, Juvet SC, Medin JA, Martinu T, Oishi H, Keshavjee S.

J Thorac Cardiovasc Surg. 2019 Feb;157(2):818-819. doi: 10.1016/j.jtcvs.2018.10.082. No abstract available.


Neutrophil extracellular traps in ex vivo lung perfusion perfusate predict the clinical outcome of lung transplant recipients.

Caldarone L, Mariscal A, Sage A, Khan M, Juvet S, Martinu T, Zamel R, Cypel M, Liu M, Palaniyar N, Keshavjee S.

Eur Respir J. 2019 Apr 4;53(4). pii: 1801736. doi: 10.1183/13993003.01736-2018. Print 2019 Apr. No abstract available.


Spectrum of chronic lung allograft pathology in a mouse minor-mismatched orthotopic lung transplant model.

Martinu T, Oishi H, Juvet SC, Cypel M, Liu M, Berry GJ, Hwang DM, Keshavjee S.

Am J Transplant. 2019 Jan;19(1):247-258. doi: 10.1111/ajt.15167. Epub 2018 Nov 29.


A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice.

Oishi H, Juvet SC, Martinu T, Sato M, Medin JA, Liu M, Keshavjee S.

J Thorac Cardiovasc Surg. 2018 Sep;156(3):1305-1315. doi: 10.1016/j.jtcvs.2018.05.003. Epub 2018 May 29.


Sequential broncho-alveolar lavages reflect distinct pulmonary compartments: clinical and research implications in lung transplantation.

Levy L, Juvet SC, Boonstra K, Singer LG, Azad S, Joe B, Cypel M, Keshavjee S, Martinu T.

Respir Res. 2018 May 25;19(1):102. doi: 10.1186/s12931-018-0786-z.


Comprehensive outcomes after lung retransplantation: A single-center review.

Halloran K, Aversa M, Tinckam K, Martinu T, Binnie M, Chaparro C, Chow CW, Waddell T, McRae K, Pierre A, de Perrot M, Yasufuku K, Cypel M, Keshavjee S, Singer LG.

Clin Transplant. 2018 Jun;32(6):e13281. doi: 10.1111/ctr.13281. Epub 2018 Jun 3.


Quantitative chest CT for subtyping chronic lung allograft dysfunction and its association with survival.

Horie M, Salazar P, Saito T, Binnie M, Brock K, Yasufuku K, Azad S, Keshavjee S, Martinu T, Paul N.

Clin Transplant. 2018 May;32(5):e13233. doi: 10.1111/ctr.13233. Epub 2018 Apr 10.


Acute Cellular Rejection: Is It Still Relevant?

Koutsokera A, Levy L, Pal P, Orchanian-Cheff A, Martinu T.

Semin Respir Crit Care Med. 2018 Apr;39(2):181-198. doi: 10.1055/s-0037-1617424. Epub 2018 Mar 26. Review.


Upregulation of alveolar neutrophil enzymes and long pentraxin-3 in human chronic lung allograft dysfunction subtypes.

Saito T, Liu M, Binnie M, Martinu T, Sato M, Keshavjee S.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2774-2776.e2. doi: 10.1016/j.jtcvs.2018.02.039. Epub 2018 Feb 23. No abstract available.


Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model.

Yoshida M, Oishi H, Martinu T, Hwang DM, Takizawa H, Sugihara J, McKee TD, Bai X, Guana Z, Lua C, Cho HR, Juvet S, Cypel M, Keshavjee S, Liu M.

Oncotarget. 2018 Jan 3;9(9):8489-8501. doi: 10.18632/oncotarget.23902. eCollection 2018 Feb 2.


Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion.

Iskender I, Cypel M, Martinu T, Chen M, Sakamoto J, Kim H, Yu K, Lin H, Guan Z, Hashimoto K, Waddell TK, Liu M, Keshavjee S.

Transplantation. 2018 May;102(5):760-768. doi: 10.1097/TP.0000000000002140.


Introduction to the 59th Annual Thomas L. Petty Aspen Lung Conference. Lung Transplantation: Opportunities for Repair and Regeneration.

Zamora MR, Martinu T, Nicolls MR.

Ann Am Thorac Soc. 2017 Sep;14(Suppl_3):S209. doi: 10.1513/AnnalsATS.201705-393MG. No abstract available.


Donor bronchial wash bile acid and suitability of donor lungs for transplantation.

Nakajima D, Cypel M, Martinu T, Liu M, Keshavjee S.

J Heart Lung Transplant. 2017 Aug 12. pii: S1053-2498(17)31950-2. doi: 10.1016/j.healun.2017.08.005. [Epub ahead of print] No abstract available.


Human Leukocyte Antigen Sensitization in Solid Organ Transplantation: A Primer on Terminology, Testing, and Clinical Significance for the Apheresis Practitioner.

Abbes S, Metjian A, Gray A, Martinu T, Snyder L, Chen DF, Ellis M, Arepally GM, Onwuemene O.

Ther Apher Dial. 2017 Oct;21(5):441-450. doi: 10.1111/1744-9987.12570. Epub 2017 Sep 7. Review.


Chronic Airway Fibrosis in Orthotopic Mouse Lung Transplantation Models-An Experimental Reappraisal.

Yamada Y, Windirsch K, Dubs L, Kenkel D, Jang JH, Inci I, Boss A, Martinu T, Vanaudenaerde B, Weder W, Jungraithmayr W.

Transplantation. 2018 Feb;102(2):e49-e58. doi: 10.1097/TP.0000000000001917.


Lung Lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury.

Nakajima D, Liu M, Ohsumi A, Kalaf R, Iskender I, Hsin M, Kanou T, Chen M, Baer B, Coutinho R, Maahs L, Behrens P, Azad S, Martinu T, Waddell TK, Lewis JF, Post M, Veldhuizen RAW, Cypel M, Keshavjee S.

J Heart Lung Transplant. 2017 May;36(5):577-585. doi: 10.1016/j.healun.2016.11.010. Epub 2016 Dec 1.


Successful Lung Transplantation From Hepatitis C Positive Donor to Seronegative Recipient.

Khan B, Singer LG, Lilly LB, Chaparro C, Martinu T, Juvet S, Pipkin M, Waddell TK, Keshavjee S, Humar A, Cypel M.

Am J Transplant. 2017 Apr;17(4):1129-1131. doi: 10.1111/ajt.14137. Epub 2017 Jan 16.


Radical and Nitrenoid Reactivity of 3-Halo-3-phenyldiazirines.

Navrátil R, Tarábek J, Linhart I, Martinů T.

Org Lett. 2016 Aug 5;18(15):3734-7. doi: 10.1021/acs.orglett.6b01753. Epub 2016 Jul 20.


De Novo DQ Donor-Specific Antibodies Are Associated with Chronic Lung Allograft Dysfunction after Lung Transplantation.

Tikkanen JM, Singer LG, Kim SJ, Li Y, Binnie M, Chaparro C, Chow CW, Martinu T, Azad S, Keshavjee S, Tinckam K.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):596-606. doi: 10.1164/rccm.201509-1857OC.


Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model.

Oishi H, Martinu T, Sato M, Matsuda Y, Hirayama S, Juvet SC, Guan Z, Saito T, Cypel M, Hwang DM, Keller TL, Whitman MR, Liu M, Keshavjee S.

J Heart Lung Transplant. 2016 Apr;35(4):518-27. doi: 10.1016/j.healun.2015.12.003. Epub 2015 Dec 10.


Biobehavioral Prognostic Factors in Chronic Obstructive Pulmonary Disease: Results From the INSPIRE-II Trial.

Blumenthal JA, Smith PJ, Durheim M, Mabe S, Emery CF, Martinu T, Diaz PT, Babyak M, Welty-Wolf K, Palmer S.

Psychosom Med. 2016 Feb-Mar;78(2):153-62. doi: 10.1097/PSY.0000000000000260.


Ex Vivo Perfusion Treatment of Infection in Human Donor Lungs.

Nakajima D, Cypel M, Bonato R, Machuca TN, Iskender I, Hashimoto K, Linacre V, Chen M, Coutinho R, Azad S, Martinu T, Waddell TK, Hwang DM, Husain S, Liu M, Keshavjee S.

Am J Transplant. 2016 Apr;16(4):1229-37. doi: 10.1111/ajt.13562. Epub 2016 Jan 5.


Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study.

Verleden SE, Todd JL, Sato M, Palmer SM, Martinu T, Pavlisko EN, Vos R, Neyrinck A, Van Raemdonck D, Saito T, Oishi H, Keshavjee S, Greer M, Warnecke G, Gottlieb J, Haverich A.

Am J Transplant. 2015 Aug;15(8):2223-30. doi: 10.1111/ajt.13281. Epub 2015 Apr 30.


Six-minute-walk distance and accelerometry predict outcomes in chronic obstructive pulmonary disease independent of Global Initiative for Chronic Obstructive Lung Disease 2011 Group.

Durheim MT, Smith PJ, Babyak MA, Mabe SK, Martinu T, Welty-Wolf KE, Emery CF, Palmer SM, Blumenthal JA.

Ann Am Thorac Soc. 2015 Mar;12(3):349-56. doi: 10.1513/AnnalsATS.201408-365OC.


Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection.

Gowdy KM, Martinu T, Nugent JL, Manzo ND, Zhang HL, Kelly FL, Holtzman MJ, Palmer SM.

Transpl Immunol. 2015 Jan;32(1):51-60. doi: 10.1016/j.trim.2014.10.005. Epub 2014 Nov 5.


Evidence for the cyclic CN2 carbene in the gas phase.

Hanzlová E, Váňa J, Shaffer CJ, Roithová J, Martinů T.

Org Lett. 2014 Oct 17;16(20):5482-5. doi: 10.1021/ol5027602. Epub 2014 Oct 8.


The effects of a telehealth coping skills intervention on outcomes in chronic obstructive pulmonary disease: primary results from the INSPIRE-II study.

Blumenthal JA, Emery CF, Smith PJ, Keefe FJ, Welty-Wolf K, Mabe S, Martinu T, Johnson JJ, Babyak MA, O'Hayer VF, Diaz PT, Durheim M, Baucom D, Palmer SM.

Psychosom Med. 2014 Oct;76(8):581-92. doi: 10.1097/PSY.0000000000000101.


Role of C-C motif ligand 2 and C-C motif receptor 2 in murine pulmonary graft-versus-host disease after lipopolysaccharide inhalations.

Martinu T, Gowdy KM, Nugent JL, Sun J, Kinnier CV, Nelson ME, Lyes MA, Kelly FL, Foster WM, Gunn MD, Palmer SM.

Am J Respir Cell Mol Biol. 2014 Dec;51(6):810-21. doi: 10.1165/rcmb.2013-0451OC.


Allogeneic splenocyte transfer and lipopolysaccharide inhalations induce differential T cell expansion and lung injury: a novel model of pulmonary graft-versus-host disease.

Martinu T, Kinnier CV, Sun J, Kelly FL, Nelson ME, Garantziotis S, Foster WM, Palmer SM.

PLoS One. 2014 May 20;9(5):e97951. doi: 10.1371/journal.pone.0097951. eCollection 2014.


Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans.

Kelly FL, Sun J, Fischer BM, Voynow JA, Kummarapurugu AB, Zhang HL, Nugent JL, Beasley RF, Martinu T, Gwinn WM, Morgan DL, Palmer SM.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):568-74. doi: 10.1165/rcmb.2013-0339OC.


Evidence for the cyclic CN2 carbene in solution.

Hanzlová E, Navrátil R, Čejka J, Böhm S, Martinů T.

Org Lett. 2014 Feb 7;16(3):852-5. doi: 10.1021/ol4036243. Epub 2014 Jan 17.


Neurobehavioral functioning and survival following lung transplantation.

Smith PJ, Blumenthal JA, Carney RM, Freedland KE, O'Hayer CVF, Trulock EP, Martinu T, Schwartz TA, Hoffman BM, Koch GG, Davis RD, Palmer SM.

Chest. 2014 Mar 1;145(3):604-611. doi: 10.1378/chest.12-2127.


Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease.

Doyle T, Palmer S, Johnson J, Babyak MA, Smith P, Mabe S, Welty-Wolf K, Martinu T, Blumenthal JA.

Int J Psychiatry Med. 2013;45(2):189-202.


Acute cellular and antibody-mediated allograft rejection.

McManigle W, Pavlisko EN, Martinu T.

Semin Respir Crit Care Med. 2013 Jun;34(3):320-35. doi: 10.1055/s-0033-1348471. Epub 2013 Jul 2. Review.


Changes in neurocognitive functioning following lung transplantation.

Hoffman BM, Blumenthal JA, Carney RC, O'Hayer CV, Freedland K, Smith PJ, Babyak MA, Davis RD, Mathew JP, Martinu T, Palmer S.

Am J Transplant. 2012 Sep;12(9):2519-25. doi: 10.1111/j.1600-6143.2012.04072.x. Epub 2012 Apr 30.

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