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The relationship between heart rate and VO2 in moderate-to-severe asthmatics.

Rodrigues Mendes FA, Teixeira RN, Martins MA, Cukier A, Stelmach R, Medeiros WM, Carvalho CRF.

J Asthma. 2019 Jul 3:1-9. doi: 10.1080/02770903.2019.1606235. [Epub ahead of print]


Synthesis of N-Pyrrolyl(furanyl)-Substituted Piperazines, 1,4-Dizepanes, and 1,4-Diazocanes.

Mittersteiner M, Andrade VP, Zachow LL, Frizzo CP, Bonacorso HG, Martins MAP, Zanatta N.

J Org Chem. 2019 Jul 1. doi: 10.1021/acs.joc.9b00867. [Epub ahead of print]


A possible association between fructose consumption and pulmonary emphysema.

Suehiro CL, Toledo-Arruda AC, Vieira RP, Almeida FM, Olivo CR, Martins MA, Lin CJ.

Sci Rep. 2019 Jun 27;9(1):9344. doi: 10.1038/s41598-019-45594-1.


Combination of trace elements and salt stress in different cultivation modes improves the lipid productivity of Scenedesmus spp.

Rocha DN, Martins MA, Soares J, Vaz MGMV, de Oliveira Leite M, Covell L, Mendes LBB.

Bioresour Technol. 2019 Jun 12;289:121644. doi: 10.1016/j.biortech.2019.121644. [Epub ahead of print]


Comparison of photobiomodulation using either an intraoral or an extraoral laser on oral mucositis induced by chemotherapy in rats.

Thieme S, Ribeiro JT, Dos Santos BG, de Almeida Zieger R, Severo MLB, Martins MAT, Matté C, Martins MD.

Support Care Cancer. 2019 Jun 4. doi: 10.1007/s00520-019-04889-9. [Epub ahead of print]


Protocol of a clinical trial study involving educational intervention in patients treated with warfarin.

Costa JMD, Marcolino MS, Torres HC, Resende RE, Souza RP, Barbosa HC, Ribeiro DD, Martins MAP.

Medicine (Baltimore). 2019 May;98(22):e15829. doi: 10.1097/MD.0000000000015829.


Pneumopericardium: a rare case of cardiorespiratory arrest.

Tonial CT, Garcia PCR, Victora J, Costa CAD, Velasques JS, Martins MA.

Einstein (Sao Paulo). 2019 May 6;17(3):eAI4516. doi: 10.31744/einstein_journal/2019AI4516. English, Portuguese. No abstract available.


Glucagon reduces airway hyperreactivity, inflammation, and remodeling induced by ovalbumin.

Insuela DBR, Azevedo CT, Coutinho DS, Magalhães NS, Ferrero MR, Ferreira TPT, Cascabulho CM, Henriques-Pons A, Olsen PC, Diaz BL, Silva PMR, Cordeiro RSB, Martins MA, Carvalho VF.

Sci Rep. 2019 Apr 24;9(1):6478. doi: 10.1038/s41598-019-42981-6.


iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice.

Prado CM, Righetti RF, Lopes FDTQDS, Leick EA, Arantes-Costa FM, de Almeida FM, Saldiva PHN, Mauad T, Tibério IFLC, Martins MA.

Pulm Med. 2019 Mar 11;2019:4781528. doi: 10.1155/2019/4781528. eCollection 2019.


Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysema.

Kohler JB, Cervilha DAB, Riani Moreira A, Santana FR, Farias TM, Alonso Vale MIC, Martins MA, Prado CM, Tibério IC, Ito JT, Lopes FDTQDS.

Biol Open. 2019 Apr 26;8(4). pii: bio040808. doi: 10.1242/bio.040808.


Polystyrene nanoplastics alter the cytotoxicity of human pharmaceuticals on marine fish cell lines.

Almeida M, Martins MA, Soares AMV, Cuesta A, Oliveira M.

Environ Toxicol Pharmacol. 2019 Jul;69:57-65. doi: 10.1016/j.etap.2019.03.019. Epub 2019 Mar 29.


Study of morphological properties and rheological parameters of cellulose nanofibrils of cocoa shell (Theobroma cacao L.).

Souza LO, Lessa OA, Dias MC, Tonoli GHD, Rezende DVB, Martins MA, Neves ICO, de Resende JV, Carvalho EEN, de Barros Vilas Boas EV, de Oliveira JR, Franco M.

Carbohydr Polym. 2019 Jun 15;214:152-158. doi: 10.1016/j.carbpol.2019.03.037. Epub 2019 Mar 14.


Barriers to daily life physical activities for Brazilian children with asthma: a cross-sectional study.

Sousa AW, Cabral ALB, Martins MA, Carvalho CRF.

J Asthma. 2019 Mar 28:1-9. doi: 10.1080/02770903.2019.1594249. [Epub ahead of print]


Photobiomodulation therapy modulates epigenetic events and NF-κB expression in oral epithelial wound healing.

de Farias Gabriel A, Wagner VP, Correa C, Webber LP, Pilar EFS, Curra M, Carrard VC, Martins MAT, Martins MD.

Lasers Med Sci. 2019 Feb 28. doi: 10.1007/s10103-019-02745-0. [Epub ahead of print]


Relation between oral reading fluency and reading comprehension.

Martins MA, Capellini SA.

Codas. 2019 Feb 25;31(1):e20170244. doi: 10.1590/2317-1782/20182018244. Portuguese, English.


The Th17/Treg Cytokine Imbalance in Chronic Obstructive Pulmonary Disease Exacerbation in an Animal Model of Cigarette Smoke Exposure and Lipopolysaccharide Challenge Association.

Cervilha DAB, Ito JT, Lourenço JD, Olivo CR, Saraiva-Romanholo BM, Volpini RA, Oliveira-Junior MC, Mauad T, Martins MA, Tibério IFLC, Vieira RP, Lopes FDTQS.

Sci Rep. 2019 Feb 13;9(1):1921. doi: 10.1038/s41598-019-38600-z.


Development and physical-chemical properties of pectin film reinforced with spent coffee grounds by continuous casting.

Mendes JF, Martins JT, Manrich A, Sena Neto AR, Pinheiro ACM, Mattoso LHC, Martins MA.

Carbohydr Polym. 2019 Apr 15;210:92-99. doi: 10.1016/j.carbpol.2019.01.058. Epub 2019 Jan 18.


Capsaicin inhibits lipopolysaccharide-induced adrenal steroidogenesis by raising intracellular calcium levels.

Ferreira LGB, Prevatto JP, Freitas HR, Reis RAM, Silva PMR, Martins MA, Faria RX, Carvalho VF.

Endocrine. 2019 Apr;64(1):169-175. doi: 10.1007/s12020-019-01849-5. Epub 2019 Feb 7.


Chemo- and regioselective reactions of 5-bromo enones/enaminones with pyrazoles.

Moraes PA, Lobo MM, Marangoni MA, Meyer AR, Frizzo CP, Bonacorso HG, Martins MAP, Zanatta N.

Org Biomol Chem. 2019 Feb 27;17(9):2384-2392. doi: 10.1039/c9ob00234k.


Mucoadhesive formulation containing Curcuma longa L. reduces oral mucositis induced by 5-fluorouracil in hamsters.

Schmidt TR, Curra M, Wagner VP, Martins MAT, de Oliveira AC, Batista AC, Valadares MC, Marreto RN, Martins MD.

Phytother Res. 2019 Apr;33(4):881-890. doi: 10.1002/ptr.6279. Epub 2019 Jan 23.


Vaccine protection against SIVmac239 acquisition.

Martins MA, Bischof GF, Shin YC, Lauer WA, Gonzalez-Nieto L, Watkins DI, Rakasz EG, Lifson JD, Desrosiers RC.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1739-1744. doi: 10.1073/pnas.1814584116. Epub 2019 Jan 14.


Th17/Treg imbalance in COPD progression: A temporal analysis using a CS-induced model.

Ito JT, Cervilha DAB, Lourenço JD, Gonçalves NG, Volpini RA, Caldini EG, Landman G, Lin CJ, Velosa APP, Teodoro WPR, Tibério IFLC, Mauad T, Martins MA, Macchione M, Lopes FDTQDS.

PLoS One. 2019 Jan 10;14(1):e0209351. doi: 10.1371/journal.pone.0209351. eCollection 2019.


Human Mesenchymal Stem Cell Therapy Reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice.

Alencar AKN, Pimentel-Coelho PM, Montes GC, da Silva MMC, Mendes LVP, Montagnoli TL, Silva AMS, Vasques JF, Rosado-de-Castro PH, Gutfilen B, Cunha VDMN, Fraga AGM, Silva PMRE, Martins MA, Ferreira TPT, Mendes-Otero R, Trachez MM, Sudo RT, Zapata-Sudo G.

Front Pharmacol. 2018 Dec 6;9:1395. doi: 10.3389/fphar.2018.01395. eCollection 2018.


The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in Mamu-B*08+ Rhesus Macaques.

Martins MA, Gonzalez-Nieto L, Shin YC, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Pedreño-Lopez N, Bailey VK, Altman JD, Parks CL, Allison DB, Ejima K, Rakasz EG, Capuano S 3rd, Desrosiers RC, Lifson JD, Watkins DI.

J Virol. 2019 Feb 19;93(5). pii: e01626-18. doi: 10.1128/JVI.01626-18. Print 2019 Mar 1.


Author Correction: Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice.

de Genaro IS, de Almeida FM, Hizume-Kunzler DC, Moriya HT, Silva RA, Cruz JCG, Lopes RB, Righetti RF, de Paula Vieira R, Saiki M, Martins MA, Tibério IFLC, Arantes-Costa FM, Saraiva-Romanholo BM.

Sci Rep. 2018 Dec 12;8(1):17899. doi: 10.1038/s41598-018-36667-8.


Gender differences in the perception of quality of life during internal medicine training: a qualitative and quantitative analysis.

Kobayasi R, Tempski PZ, Arantes-Costa FM, Martins MA.

BMC Med Educ. 2018 Nov 26;18(1):281. doi: 10.1186/s12909-018-1378-9.


Suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups.

Castro JCDSXE, Botelho SF, Machado TRL, Martins MAP, Vieira LB, Reis AMM.

Einstein (Sao Paulo). 2018 Nov 8;16(4):eAO4354. doi: 10.31744/einstein_journal/2018AO4354. English, Portuguese.


A plant proteinase inhibitor from Enterolobium contortisiliquum attenuates airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma.

Rodrigues APD, Bortolozzo ASS, Arantes-Costa FM, Saraiva-Romanholo BM, de Souza FCR, Brüggemann TR, Santana FPR, de Brito MV, Bonturi CR, Nunes NNDS, Prado CM, Leick EA, Oliva MLV, Martins MA, Righetti RF, Tibério IFLC.

Histol Histopathol. 2019 May;34(5):537-552. doi: 10.14670/HH-18-059. Epub 2018 Nov 8.


Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative.

Bastos ITS, Pinheiro PSM, Costa FN, Rocha MD, Sant'Anna CMR, Braz D, Souza ET, Martins MA, Barreiro EJ, Ferreira FF, Barroso RC, Fraga CAM.

Pharmaceuticals (Basel). 2018 Nov 1;11(4). pii: E119. doi: 10.3390/ph11040119.


Vesicular acetylcholine transport deficiency potentiates some inflammatory responses induced by diesel exhaust particles.

Santana FPR, Pinheiro NM, Bittencourt-Mernak MI, Perini A, Yoshizaki K, Macchione M, Saldiva PHN, Martins MA, Tibério IFLC, Prado MAM, Prado VF, Prado CM.

Ecotoxicol Environ Saf. 2019 Jan 15;167:494-504. doi: 10.1016/j.ecoenv.2018.10.005. Epub 2018 Oct 25.


The Plant Proteinase Inhibitor CrataBL Plays a Role in Controlling Asthma Response in Mice.

Bortolozzo ASS, Rodrigues APD, Arantes-Costa FM, Saraiva-Romanholo BM, de Souza FCR, Brüggemann TR, de Brito MV, Ferreira RDS, Correia MTDS, Paiva PMG, Prado CM, Leick EA, Oliva MLV, Martins MA, Ruiz-Schutz VC, Righetti RF, Tibério IFLC.

Biomed Res Int. 2018 Oct 1;2018:9274817. doi: 10.1155/2018/9274817. eCollection 2018.


Predictive ability of scores for bleeding risk in heart disease outpatients on warfarin in Brazil.

Oliveira JAQ, Pinho Ribeiro AL, Ribeiro DD, Nobre V, Rocha MODC, Martins MAP.

PLoS One. 2018 Oct 19;13(10):e0205970. doi: 10.1371/journal.pone.0205970. eCollection 2018.


Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice.

Righetti RF, Dos Santos TM, Camargo LDN, Aristóteles LRCRB, Fukuzaki S, de Souza FCR, Santana FPR, de Agrela MVR, Cruz MM, Alonso-Vale MIC, Genaro IS, Saraiva-Romanholo BM, Leick EA, Martins MA, Prado CM, Tibério IFLC.

Front Pharmacol. 2018 Oct 4;9:1021. doi: 10.3389/fphar.2018.01021. eCollection 2018.


Effects of polymethylmethacrylate nanoplastics on Dicentrarchus labrax.

Brandts I, Teles M, Tvarijonaviciute A, Pereira ML, Martins MA, Tort L, Oliveira M.

Genomics. 2018 Nov;110(6):435-441. doi: 10.1016/j.ygeno.2018.10.006. Epub 2018 Oct 11.


Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma.

Dos Santos TM, Righetti RF, Camargo LDN, Saraiva-Romanholo BM, Aristoteles LRCRB, de Souza FCR, Fukuzaki S, Alonso-Vale MIC, Cruz MM, Prado CM, Leick EA, Martins MA, Tibério IFLC.

Front Physiol. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183. eCollection 2018.


Efficacy of diode-emitting diode (LED) photobiomodulation in pain management, facial edema, trismus, and quality of life after extraction of retained lower third molars: A randomized, double-blind, placebo-controlled clinical trial.

Tenis CA, Martins MD, Gonçalves MLL, Silva DFTD, Cunha Filho JJD, Martins MAT, Mesquita-Ferrari RA, Bussadori SK, Fernandes KPS.

Medicine (Baltimore). 2018 Sep;97(37):e12264. doi: 10.1097/MD.0000000000012264. Erratum in: Medicine (Baltimore). 2018 Oct;97(41):e12882.


Glucocorticoids decrease the numbers and activation of mast cells by inducing the transactivation receptors of AGEs.

Santoro T, Azevedo CT, E Silva PMR, Martins MA, Carvalho VF.

J Leukoc Biol. 2019 Jan;105(1):131-142. doi: 10.1002/JLB.3A0917-364RR. Epub 2018 Sep 10.


Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice.

de Genaro IS, de Almeida FM, Hizume-Kunzler DC, Moriya HT, Silva RA, Cruz JCG, Lopes RB, Righetti RF, de Paula Vieira R, Saiki M, Martins MA, Tibério IFLC, Arantes-Costa FM, Saraiva-Romanholo BM.

Sci Rep. 2018 Aug 22;8(1):12636. doi: 10.1038/s41598-018-30851-6. Erratum in: Sci Rep. 2018 Dec 12;8(1):17899.


Drug therapy and other factors associated with the development of acute kidney injury in critically ill patients: a cross-sectional study.

Soares DB, Mambrini JVM, Botelho GR, Girundi FF, Botoni FA, Martins MAP.

PeerJ. 2018 Aug 14;6:e5405. doi: 10.7717/peerj.5405. eCollection 2018.


Effect of slight structural changes on the gelation properties of N-phenylstearamide supramolecular gels.

Meyer AR, Bender CR, Dos Santos DM, Ziembowicz FI, Frizzo CP, Villetti MA, Reichert JM, Zanatta N, Bonacorso HG, Martins MAP.

Soft Matter. 2018 Aug 15;14(32):6716-6727. doi: 10.1039/c8sm00961a.


Impact of Anions on the Partition Constant, Self-Diffusion, Thermal Stability, and Toxicity of Dicationic Ionic Liquids.

Frizzo CP, Bender CR, Salbego PRS, Farias CAA, da Silva TC, Stefanello ST, da Silveira TL, Soares FAA, Villetti MA, Martins MAP.

ACS Omega. 2018 Jan 31;3(1):734-743. doi: 10.1021/acsomega.7b01873. Epub 2018 Jan 22.


Sustainable hydrophobic terpene-based eutectic solvents for the extraction and separation of metals.

Schaeffer N, Martins MAR, Neves CMSS, Pinho SP, Coutinho JAP.

Chem Commun (Camb). 2018 Jul 17;54(58):8104-8107. doi: 10.1039/c8cc04152k.


Seasonal changes influence the improvement in asthma symptoms by exercise training in subjects with asthma*.

Mendes FAR, França-Pinto A, Martins MA, Cukier A, Stelmach R, Giavina-Bianchi P, Carvalho CRF.

J Asthma. 2019 Jun;56(6):674-679. doi: 10.1080/02770903.2018.1484131. Epub 2018 Oct 5.


Effects of nanoplastics on Mytilus galloprovincialis after individual and combined exposure with carbamazepine.

Brandts I, Teles M, Gonçalves AP, Barreto A, Franco-Martinez L, Tvarijonaviciute A, Martins MA, Soares AMVM, Tort L, Oliveira M.

Sci Total Environ. 2018 Dec 1;643:775-784. doi: 10.1016/j.scitotenv.2018.06.257. Epub 2018 Jun 27.


Repeated Allergen Exposure in A/J Mice Causes Steroid-Insensitive Asthma via a Defect in Glucocorticoid Receptor Bioavailability.

Serra MF, Cotias AC, Pão CRR, Daleprane JB, Jurgilas PB, Couto GC, Anjos-Valotta EA, Cordeiro RSB, Carvalho VF, Silva PMR, Martins MA.

J Immunol. 2018 Aug 1;201(3):851-860. doi: 10.4049/jimmunol.1700933. Epub 2018 Jun 18.


A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products.

Shin YC, Bischof GF, Lauer WA, Gonzalez-Nieto L, Rakasz EG, Hendricks GM, Watkins DI, Martins MA, Desrosiers RC.

PLoS Pathog. 2018 Jun 18;14(6):e1007143. doi: 10.1371/journal.ppat.1007143. eCollection 2018 Jun.


Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.

Martins MA, Tully DC, Pedreño-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, Bailey VK, Altman JD, Burton DR, Ejima K, Allison DB, Evans DT, Rakasz EG, Parks CL, Bonaldo MC, Capuano S 3rd, Lifson JD, Desrosiers RC, Allen TM, Watkins DI.

J Virol. 2018 Jul 31;92(16). pii: e00690-18. doi: 10.1128/JVI.00690-18. Print 2018 Aug 15.


Evaluation of accuracy of IHI Trigger Tool in identifying adverse drug events: a prospective observational study.

Silva MDDG, Martins MAP, Viana LG, Passaglia LG, de Menezes RR, Oliveira JAQ, da Silva JLP, Ribeiro ALP.

Br J Clin Pharmacol. 2018 Oct;84(10):2252-2259. doi: 10.1111/bcp.13665. Epub 2018 Jul 8.


Capybara Oil Improves Hepatic Mitochondrial Dysfunction, Steatosis, and Inflammation in a Murine Model of Nonalcoholic Fatty Liver Disease.

Marinho PC, Vieira AB, Pereira PG, Rabelo K, Ciambarella BT, Nascimento ALR, Cortez E, Moura AS, Guimarães FV, Martins MA, Barquero G, Ferreira RN, de Carvalho JJ.

Evid Based Complement Alternat Med. 2018 Apr 29;2018:4956079. doi: 10.1155/2018/4956079. eCollection 2018.


Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice.

Carvalho VF, Barreto EO, Arantes ACS, Serra MF, Ferreira TPT, Jannini-Sá YAP, Hogaboam CM, Martins MA, Silva PMR.

Mediators Inflamm. 2018 Apr 15;2018:6150843. doi: 10.1155/2018/6150843. eCollection 2018.

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