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Items: 13

1.

SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.

Santos-Barriopedro I, Bosch-Presegué L, Marazuela-Duque A, de la Torre C, Colomer C, Vazquez BN, Fuhrmann T, Martínez-Pastor B, Lu W, Braun T, Bober E, Jenuwein T, Serrano L, Esteller M, Chen Z, Barceló-Batllori S, Mostoslavsky R, Espinosa L, Vaquero A.

Nat Commun. 2018 Jan 9;9(1):101. doi: 10.1038/s41467-017-02586-x.

2.

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.

Lobbardi R, Pinder J, Martinez-Pastor B, Theodorou M, Blackburn JS, Abraham BJ, Namiki Y, Mansour M, Abdelfattah NS, Molodtsov A, Alexe G, Toiber D, de Waard M, Jain E, Boukhali M, Lion M, Bhere D, Shah K, Gutierrez A, Stegmaier K, Silverman LB, Sadreyev RI, Asara JM, Oettinger MA, Haas W, Look AT, Young RA, Mostoslavsky R, Dellaire G, Langenau DM.

Cancer Discov. 2017 Nov;7(11):1336-1353. doi: 10.1158/2159-8290.CD-17-0267. Epub 2017 Oct 3.

3.

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, Goren A, Rao A, Mostoslavsky R.

Nat Cell Biol. 2015 May;17(5):545-57. doi: 10.1038/ncb3147. Epub 2015 Apr 27.

4.

Assaying chromatin sirtuins.

Zhong L, Martinez-Pastor B, Silberman DM, Sebastian C, Mostoslavsky R.

Methods Mol Biol. 2013;1077:149-163. doi: 10.1007/978-1-62703-637-5_10.

5.

SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling.

Toiber D, Erdel F, Bouazoune K, Silberman DM, Zhong L, Mulligan P, Sebastian C, Cosentino C, Martinez-Pastor B, Giacosa S, D'Urso A, Näär AM, Kingston R, Rippe K, Mostoslavsky R.

Mol Cell. 2013 Aug 22;51(4):454-68. doi: 10.1016/j.molcel.2013.06.018. Epub 2013 Aug 1.

6.

A tale of metabolites: the cross-talk between chromatin and energy metabolism.

Martinez-Pastor B, Cosentino C, Mostoslavsky R.

Cancer Discov. 2013 May;3(5):497-501. doi: 10.1158/2159-8290.CD-13-0059.

7.

Sirtuins, metabolism, and cancer.

Martinez-Pastor B, Mostoslavsky R.

Front Pharmacol. 2012 Feb 21;3:22. doi: 10.3389/fphar.2012.00022. eCollection 2012.

8.

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

Herranz D, Muñoz-Martin M, Cañamero M, Mulero F, Martinez-Pastor B, Fernandez-Capetillo O, Serrano M.

Nat Commun. 2010 Apr 12;1:3. doi: 10.1038/ncomms1001.

9.

Overall Cdk activity modulates the DNA damage response in mammalian cells.

Cerqueira A, Santamaría D, Martínez-Pastor B, Cuadrado M, Fernández-Capetillo O, Barbacid M.

J Cell Biol. 2009 Dec 14;187(6):773-80. doi: 10.1083/jcb.200903033.

10.

Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.

Efeyan A, Murga M, Martinez-Pastor B, Ortega-Molina A, Soria R, Collado M, Fernandez-Capetillo O, Serrano M.

PLoS One. 2009;4(5):e5475. doi: 10.1371/journal.pone.0005475. Epub 2009 May 7.

11.

Global chromatin compaction limits the strength of the DNA damage response.

Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, Cuadrado M, Yang SM, Blasco MA, Skoultchi AI, Fernandez-Capetillo O.

J Cell Biol. 2007 Sep 24;178(7):1101-8.

12.

"ATR activation in response to ionizing radiation: still ATM territory".

Cuadrado M, Martinez-Pastor B, Fernandez-Capetillo O.

Cell Div. 2006 May 17;1(1):7.

13.

ATM regulates ATR chromatin loading in response to DNA double-strand breaks.

Cuadrado M, Martinez-Pastor B, Murga M, Toledo LI, Gutierrez-Martinez P, Lopez E, Fernandez-Capetillo O.

J Exp Med. 2006 Feb 20;203(2):297-303. Epub 2006 Feb 6.

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