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Items: 43


A platform for extracellular interactome discovery identifies novel functional binding partners for the immune receptors B7-H3/CD276 and PVR/CD155.

Husain B, Ramani SR, Chiang E, Lehoux I, Paduchuri S, Arena TA, Patel A, Wilson B, Chan P, Franke Y, Wong AW, Lill JR, Turley SJ, Gonzalez LC, Grogan JL, Martinez-Martin N.

Mol Cell Proteomics. 2019 Jul 15. pii: mcp.TIR119.001433. doi: 10.1074/mcp.TIR119.001433. [Epub ahead of print]


Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy.

Chang JC, Durinck S, Chen MZ, Martinez-Martin N, Zhang JA, Lehoux I, Li H, Lin M, Wu J, Bainbridge TW, Ernst JA, Ramani SR, Paduchuri S, Kates L, Solon M, Buechler MB, Castiglioni A, Thai M, Breart B, Modrusan Z, Peterson AS, Turley SJ, Sonoda J.

Sci Rep. 2019 Jun 20;9(1):8833. doi: 10.1038/s41598-019-45354-1.


The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion.

Fearnley GW, Young KA, Edgar JR, Antrobus R, Hay IM, Liang WC, Martinez-Martin N, Lin W, Deane JE, Sharpe HJ.

Elife. 2019 Mar 29;8. pii: e44597. doi: 10.7554/eLife.44597.


What Are Important Ethical Implications of Using Facial Recognition Technology in Health Care?

Martinez-Martin N.

AMA J Ethics. 2019 Feb 1;21(2):E180-187. doi: 10.1001/amajethics.2019.180.


Cutting Edge: IL-17B Uses IL-17RA and IL-17RB to Induce Type 2 Inflammation from Human Lymphocytes.

Ramirez-Carrozzi V, Ota N, Sambandam A, Wong K, Hackney J, Martinez-Martin N, Ouyang W, Pappu R.

J Immunol. 2019 Apr 1;202(7):1935-1941. doi: 10.4049/jimmunol.1800696. Epub 2019 Feb 15.


Extracellular Protein Microarray Technology for High Throughput Detection of Low Affinity Receptor-Ligand Interactions.

Husain B, Paduchuri S, Ramani SR, Martinez-Martin N.

J Vis Exp. 2019 Jan 7;(143). doi: 10.3791/58451.


Dynamic reorganisation of intermediate filaments coordinates early B-cell activation.

Tsui C, Maldonado P, Montaner B, Borroto A, Alarcon B, Bruckbauer A, Martinez-Martin N, Batista FD.

Life Sci Alliance. 2018 Aug 20;1(5):e201800060. doi: 10.26508/lsa.201800060. eCollection 2018 Oct.


Is It Ethical to Use Prognostic Estimates from Machine Learning to Treat Psychosis?

Martinez-Martin N, Dunn LB, Roberts LW.

AMA J Ethics. 2018 Sep 1;20(9):E804-811. doi: 10.1001/amajethics.2018.804.


Surveillance and Digital Health.

Martinez-Martin N, Char D.

Am J Bioeth. 2018 Sep;18(9):67-68. doi: 10.1080/15265161.2018.1498954. No abstract available.


An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor.

Martinez-Martin N, Marcandalli J, Huang CS, Arthur CP, Perotti M, Foglierini M, Ho H, Dosey AM, Shriver S, Payandeh J, Leitner A, Lanzavecchia A, Perez L, Ciferri C.

Cell. 2018 Aug 23;174(5):1158-1171.e19. doi: 10.1016/j.cell.2018.06.028. Epub 2018 Jul 26.


Antigen phagocytosis by B cells is required for a potent humoral response.

Martínez-Riaño A, Bovolenta ER, Mendoza P, Oeste CL, Martín-Bermejo MJ, Bovolenta P, Turner M, Martínez-Martín N, Alarcón B.

EMBO Rep. 2018 Sep;19(9). pii: e46016. doi: 10.15252/embr.201846016. Epub 2018 Jul 9.


Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis.

Tsui C, Martinez-Martin N, Gaya M, Maldonado P, Llorian M, Legrave NM, Rossi M, MacRae JI, Cameron AJ, Parker PJ, Leitges M, Bruckbauer A, Batista FD.

Immunity. 2018 Jun 19;48(6):1144-1159.e5. doi: 10.1016/j.immuni.2018.04.031. Epub 2018 Jun 5.


R-Ras2 is required for germinal center formation to aid B cells during energetically demanding processes.

Mendoza P, Martínez-Martín N, Bovolenta ER, Reyes-Garau D, Hernansanz-Agustín P, Delgado P, Diaz-Muñoz MD, Oeste CL, Fernández-Pisonero I, Castellano E, Martínez-Ruiz A, Alonso-Lopez D, Santos E, Bustelo XR, Kurosaki T, Alarcón B.

Sci Signal. 2018 May 29;11(532). pii: eaal1506. doi: 10.1126/scisignal.aal1506.


Ethical Issues for Direct-to-Consumer Digital Psychotherapy Apps: Addressing Accountability, Data Protection, and Consent.

Martinez-Martin N, Kreitmair K.

JMIR Ment Health. 2018 Apr 23;5(2):e32. doi: 10.2196/mental.9423.


Data mining for health: staking out the ethical territory of digital phenotyping.

Martinez-Martin N, Insel TR, Dagum P, Greely HT, Cho MK.

NPJ Digit Med. 2018;1. pii: 68. doi: 10.1038/s41746-018-0075-8. Epub 2018 Dec 19.


Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.

Yau RG, Doerner K, Castellanos ER, Haakonsen DL, Werner A, Wang N, Yang XW, Martinez-Martin N, Matsumoto ML, Dixit VM, Rape M.

Cell. 2017 Nov 2;171(4):918-933.e20. doi: 10.1016/j.cell.2017.09.040. Epub 2017 Oct 12.


Corrigendum: The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation.

Martinez-Martin N, Ramani SR, Hackney JA, Tom I, Wranik BJ, Chan M, Wu J, Paluch MT, Takeda K, Hass PE, Clark H, Gonzalez LC.

Nat Commun. 2017 Aug 21;8:16150. doi: 10.1038/ncomms16150.


Psychiatric Genetics in a Risk Society.

Martinez-Martin N.

Am J Bioeth. 2017 Apr;17(4):1-2. doi: 10.1080/15265161.2017.1300485. No abstract available.


Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions.

Martinez-Martin N.

J Immunol Res. 2017;2017:2197615. doi: 10.1155/2017/2197615. Epub 2017 Feb 22. Review.


A switch from canonical to noncanonical autophagy shapes B cell responses.

Martinez-Martin N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, Tsui C, Burbage M, Keppler SJ, Montaner B, Jefferies HB, Nair U, Zhao YG, Domart MC, Collinson L, Bruckbauer A, Tooze SA, Batista FD.

Science. 2017 Feb 10;355(6325):641-647. doi: 10.1126/science.aal3908.


Herpes simplex virus particles interact with chemokines and enhance cell migration.

Martínez-Martín N, Viejo-Borbolla A, Alcami A.

J Gen Virol. 2016 Nov;97(11):3007-3016. doi: 10.1099/jgv.0.000616. Epub 2016 Sep 27.


The Analysis of Cell Cycle, Proliferation, and Asymmetric Cell Division by Imaging Flow Cytometry.

Filby A, Day W, Purewal S, Martinez-Martin N.

Methods Mol Biol. 2016;1389:71-95. doi: 10.1007/978-1-4939-3302-0_5.


The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation.

Martinez-Martin N, Ramani SR, Hackney JA, Tom I, Wranik BJ, Chan M, Wu J, Paluch MT, Takeda K, Hass PE, Clark H, Gonzalez LC.

Nat Commun. 2016 May 5;7:11473. doi: 10.1038/ncomms11473. Erratum in: Nat Commun. 2017 Aug 21;8:16150.


Association between maltreatment and polydrug use among adolescents.

Alvarez-Alonso MJ, Jurado-Barba R, Martinez-Martin N, Espin-Jaime JC, Bolaños-Porrero C, Ordoñez-Franco A, Rodriguez-Lopez JA, Lora-Pablos D, de la Cruz-Bértolo J, Jimenez-Arriero MA, Manzanares J, Rubio G.

Child Abuse Negl. 2016 Jan;51:379-89. doi: 10.1016/j.chiabu.2015.07.014. Epub 2015 Aug 25.


Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization.

Martinez-Martin N, Viejo-Borbolla A, Martín R, Blanco S, Benovic JL, Thelen M, Alcamí A.

Nat Commun. 2015 Jan 27;6:6163. doi: 10.1038/ncomms7163.


Secreted herpes simplex virus-2 glycoprotein G modifies NGF-TrkA signaling to attract free nerve endings to the site of infection.

Cabrera JR, Viejo-Borbolla A, Martinez-Martín N, Blanco S, Wandosell F, Alcamí A.

PLoS Pathog. 2015 Jan 22;11(1):e1004571. doi: 10.1371/journal.ppat.1004571. eCollection 2015 Jan.


Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.

Burbage M, Keppler SJ, Gasparrini F, Martínez-Martín N, Gaya M, Feest C, Domart MC, Brakebusch C, Collinson L, Bruckbauer A, Batista FD.

J Exp Med. 2015 Jan 12;212(1):53-72. doi: 10.1084/jem.20141143. Epub 2014 Dec 29.


β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism.

Fernández-Arenas E, Calleja E, Martínez-Martín N, Gharbi SI, Navajas R, García-Medel N, Penela P, Alcamí A, Mayor F Jr, Albar JP, Alarcón B.

EMBO J. 2014 Mar 18;33(6):559-77. doi: 10.1002/embj.201386022. Epub 2014 Feb 6.


Ethical, Legal and Social Issues Surrounding Research on Genetic Contributions to Anti-Social Behavior.

Berryessa CM, Martinez-Martin NA, Allyse MA.

Aggress Violent Behav. 2013 Nov;18(6). doi: 10.1016/j.avb.2013.07.011.


Stimulant and atypical antipsychotic medications for children placed in foster homes.

Linares LO, Martinez-Martin N, Castellanos FX.

PLoS One. 2013;8(1):e54152. doi: 10.1371/journal.pone.0054152. Epub 2013 Jan 9.


RRas2, RhoG and T-cell phagocytosis.

Alarcón B, Martínez-Martín N.

Small GTPases. 2012 Apr-Jun;3(2):97-101. doi: 10.4161/sgtp.19138.


Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses.

Viejo-Borbolla A, Martinez-Martín N, Nel HJ, Rueda P, Martín R, Blanco S, Arenzana-Seisdedos F, Thelen M, Fallon PG, Alcamí A.

PLoS Pathog. 2012 Feb;8(2):e1002497. doi: 10.1371/journal.ppat.1002497. Epub 2012 Feb 2.


Asymmetric segregation of polarized antigen on B cell division shapes presentation capacity.

Thaunat O, Granja AG, Barral P, Filby A, Montaner B, Collinson L, Martinez-Martin N, Harwood NE, Bruckbauer A, Batista FD.

Science. 2012 Jan 27;335(6067):475-9. doi: 10.1126/science.1214100.


Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells.

Martínez-Martín N, Blas-García A, Morales JM, Marti-Cabrera M, Monleón D, Apostolova N.

Int J Mol Med. 2012 Jan;29(1):88-94. doi: 10.3892/ijmm.2011.802. Epub 2011 Sep 28.


Self-perceived needs are related to violent behavior among schizophrenia outpatients.

Martínez-Martín N, Fraguas D, García-Portilla MP, Sáiz PA, Bascarán MT, Arango C, Bobes J.

J Nerv Ment Dis. 2011 Sep;199(9):666-71. doi: 10.1097/NMD.0b013e318229d0d5.


T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis.

Martínez-Martín N, Fernández-Arenas E, Cemerski S, Delgado P, Turner M, Heuser J, Irvine DJ, Huang B, Bustelo XR, Shaw A, Alarcón B.

Immunity. 2011 Aug 26;35(2):208-22. doi: 10.1016/j.immuni.2011.06.003. Epub 2011 Aug 4.


The immunological synapse: a cause or consequence of T-cell receptor triggering?

Alarcón B, Mestre D, Martínez-Martín N.

Immunology. 2011 Aug;133(4):420-5. doi: 10.1111/j.1365-2567.2011.03458.x. Epub 2011 Jun 2. Review.


Cytotoxic T cells. Handing over the baton.

Alarcón B, Martínez-Martin N.

Immunol Cell Biol. 2010 Jul;88(5):505-6. doi: 10.1038/icb.2010.50. Epub 2010 Apr 13. No abstract available.


Toll-like receptor-mediated recognition of herpes simplex virus.

Martinez-Martin N, Viejo-Borbolla A.

Front Biosci (Schol Ed). 2010 Jan 1;2:718-29. Review.


Cooperativity between T cell receptor complexes revealed by conformational mutants of CD3epsilon.

Martínez-Martín N, Risueño RM, Morreale A, Zaldívar I, Fernández-Arenas E, Herranz F, Ortiz AR, Alarcón B.

Sci Signal. 2009 Aug 11;2(83):ra43. doi: 10.1126/scisignal.2000402.


Essential function for the GTPase TC21 in homeostatic antigen receptor signaling.

Delgado P, Cubelos B, Calleja E, Martínez-Martín N, Ciprés A, Mérida I, Bellas C, Bustelo XR, Alarcón B.

Nat Immunol. 2009 Aug;10(8):880-8. doi: 10.1038/ni.1749. Epub 2009 Jun 28.


The neglected intrinsic resistome of bacterial pathogens.

Fajardo A, Martínez-Martín N, Mercadillo M, Galán JC, Ghysels B, Matthijs S, Cornelis P, Wiehlmann L, Tümmler B, Baquero F, Martínez JL.

PLoS One. 2008 Feb 20;3(2):e1619. doi: 10.1371/journal.pone.0001619.


[Prevalence of vitamin D deficiency in populations at risk for osteoporosis: impact on bone integrity].

Mezquita Raya P, Muñoz Torres M, López Rodríguez F, Martínez Martín N, Conde Valero A, Ortego Centeno N, González Calvín J, Raya Alvarez E, Luna Jd Jde D, Escobar Jiménez F.

Med Clin (Barc). 2002 Jun 22;119(3):85-9. Spanish.


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