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Synthesis of ABBV-168, a 2'-Bromouridine for the Treatment of Hepatitis C.

Voight EA, Brown BS, Greszler SN, Halvorsen GT, Zhao G, Kruger AW, Hartung J, Lukin KA, Martinez SR, Moschetta EG, Tudesco MT, Ide ND.

J Org Chem. 2018 Nov 19. doi: 10.1021/acs.joc.8b02341. [Epub ahead of print]


Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells.

Woods-Burnham L, Cajigas-Du Ross CK, Love A, Basu A, Sanchez-Hernandez ES, Martinez SR, Ortiz-Hernández GL, Stiel L, Durán AM, Wilson C, Montgomery S, Roy S, Casiano CA.

Sci Rep. 2018 Oct 10;8(1):15063. doi: 10.1038/s41598-018-33150-2.


Asymmetric Synthesis of Remote Quaternary Centers by Copper-Catalyzed Desymmetrization: An Enantioselective Total Synthesis of (+)-Mesembrine.

Bokka A, Mao JX, Hartung J, Martinez SR, Simanis JA, Nam K, Jeon J, Shen X.

Org Lett. 2018 Sep 7;20(17):5158-5162. doi: 10.1021/acs.orglett.8b02084. Epub 2018 Aug 24.


RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance.

Cajigas-Du Ross CK, Martinez SR, Woods-Burnham L, Durán AM, Roy S, Basu A, Ramirez JA, Ortiz-Hernández GL, Ríos-Colón L, Chirshev E, Sanchez-Hernandez ES, Soto U, Greco C, Boucheix C, Chen X, Unternaehrer J, Wang C, Casiano CA.

Oncotarget. 2018 Jul 13;9(54):30363-30384. doi: 10.18632/oncotarget.25744. eCollection 2018 Jul 13.


MicroRNA-210 suppresses glucocorticoid receptor expression in response to hypoxia in fetal rat cardiomyocytes.

Martinez SR, Ma Q, Dasgupta C, Meng X, Zhang L.

Oncotarget. 2017 May 11;8(46):80249-80264. doi: 10.18632/oncotarget.17801. eCollection 2017 Oct 6.


Total small vessel disease burden and brain network efficiency in cerebral amyloid angiopathy.

Valenti R, Reijmer YD, Charidimou A, Boulouis G, Martinez SR, Xiong L, Fotiadis P, Jessel M, Ayres A, Riley G, Pantoni L, Edip Gurol M, Greenberg SM, Viswanathan A.

J Neurol Sci. 2017 Nov 15;382:10-12. doi: 10.1016/j.jns.2017.09.015. Epub 2017 Sep 12.


Age-based disparities in the use of total thyroidectomy for papillary thyroid carcinoma.

Shevchyk IV, Cobian BA, Martinez SR.

Clin Transl Oncol. 2017 Oct;19(10):1253-1259. doi: 10.1007/s12094-017-1663-9. Epub 2017 Apr 24.


meso-Acetoxymethyl BODIPY dyes for photodynamic therapy: improved photostability of singlet oxygen photosensitizers.

Lincoln R, Durantini AM, Greene LE, Martínez SR, Knox R, Becerra MC, Cosa G.

Photochem Photobiol Sci. 2017 Feb 15;16(2):178-184. doi: 10.1039/c6pp00166a.


TSLP or IL-7 provide an IL-7Rα signal that is critical for human B lymphopoiesis.

Milford TA, Su RJ, Francis OL, Baez I, Martinez SR, Coats JS, Weldon AJ, Calderon MN, Nwosu MC, Botimer AR, Suterwala BT, Zhang XB, Morris CL, Weldon DJ, Dovat S, Payne KJ.

Eur J Immunol. 2016 Sep;46(9):2155-61. doi: 10.1002/eji.201646307. Epub 2016 Jul 12.


Evaluation of Antibacterial Activity and Reactive Species Generation of N-Benzenesulfonyl Derivatives of Heterocycles.

Martínez SR, Miana GE, Albesa I, Mazzieri MR, Becerra MC.

Chem Pharm Bull (Tokyo). 2016;64(2):135-41. doi: 10.1248/cpb.c15-00682.


Reactive Oxygen Species Mediated Activation of a Dormant Singlet Oxygen Photosensitizer: From Autocatalytic Singlet Oxygen Amplification to Chemicontrolled Photodynamic Therapy.

Durantini AM, Greene LE, Lincoln R, Martínez SR, Cosa G.

J Am Chem Soc. 2016 Feb 3;138(4):1215-25. doi: 10.1021/jacs.5b10288. Epub 2016 Jan 20.


Antenatal hypoxia induces epigenetic repression of glucocorticoid receptor and promotes ischemic-sensitive phenotype in the developing heart.

Xiong F, Lin T, Song M, Ma Q, Martinez SR, Lv J, MataGreenwood E, Xiao D, Xu Z, Zhang L.

J Mol Cell Cardiol. 2016 Feb;91:160-71. doi: 10.1016/j.yjmcc.2016.01.003. Epub 2016 Jan 9.


LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.

Basu A, Cajigas-Du Ross CK, Rios-Colon L, Mediavilla-Varela M, Daniels-Wells TR, Leoh LS, Rojas H, Banerjee H, Martinez SR, Acevedo-Martinez S, Casiano CA.

PLoS One. 2016 Jan 15;11(1):e0146549. doi: 10.1371/journal.pone.0146549. eCollection 2016.


A novel xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis.

Francis OL, Milford TA, Martinez SR, Baez I, Coats JS, Mayagoitia K, Concepcion KR, Ginelli E, Beldiman C, Benitez A, Weldon AJ, Arogyaswamy K, Shiraz P, Fisher R, Morris CL, Zhang XB, Filippov V, Van Handel B, Ge Z, Song C, Dovat S, Su RJ, Payne KJ.

Haematologica. 2016 Apr;101(4):417-26. doi: 10.3324/haematol.2015.125336. Epub 2015 Nov 26.


Epigenetic mechanisms in heart development and disease.

Martinez SR, Gay MS, Zhang L.

Drug Discov Today. 2015 Jul;20(7):799-811. doi: 10.1016/j.drudis.2014.12.018. Epub 2015 Jan 6. Review.


Metastatic melanoma - a review of current and future treatment options.

Maverakis E, Cornelius LA, Bowen GM, Phan T, Patel FB, Fitzmaurice S, He Y, Burrall B, Duong C, Kloxin AM, Sultani H, Wilken R, Martinez SR, Patel F.

Acta Derm Venereol. 2015 May;95(5):516-24. doi: 10.2340/00015555-2035. Review.


Relative value units poorly correlate with measures of surgical effort and complexity.

Shah DR, Bold RJ, Yang AD, Khatri VP, Martinez SR, Canter RJ.

J Surg Res. 2014 Aug;190(2):465-70. doi: 10.1016/j.jss.2014.05.052. Epub 2014 May 23.


Oxytocin and postpartum depression: delivering on what's known and what's not.

Kim S, Soeken TA, Cromer SJ, Martinez SR, Hardy LR, Strathearn L.

Brain Res. 2014 Sep 11;1580:219-32. doi: 10.1016/j.brainres.2013.11.009. Epub 2013 Nov 14. Review.


Text messaging among residents and faculty in a university general surgery residency program: prevalence, purpose, and patient care.

Shah DR, Galante JM, Bold RJ, Canter RJ, Martinez SR.

J Surg Educ. 2013 Nov-Dec;70(6):826-34. doi: 10.1016/j.jsurg.2012.05.003. Epub 2012 Jun 15.


Comparative morbidity and mortality from cervical or thoracic esophageal anastomoses.

Shah DR, Martinez SR, Canter RJ, Yang AD, Bold RJ, Khatri VP.

J Surg Oncol. 2013 Dec;108(7):472-6. doi: 10.1002/jso.23423. Epub 2013 Sep 21.


Extremity soft tissue tumor surgery by surgical specialty: a comparison of case volume among oncology and non-oncology-designated surgeons.

Canter RJ, Smith CA, Martinez SR, Goodnight JE Jr, Bold RJ, Wisner DH.

J Surg Oncol. 2013 Sep;108(3):142-7. doi: 10.1002/jso.23372. Epub 2013 Jul 3.


Age-related disparities in use of completion lymphadenectomy for melanoma sentinel lymph node metastasis.

Shah DR, Yang AD, Maverakis E, Martinez SR.

J Surg Res. 2013 Nov;185(1):240-4. doi: 10.1016/j.jss.2013.05.090. Epub 2013 Jun 19.


Parathyroid carcinoma survival: improvements in the era of intact parathyroid hormone monitoring?

Allen ME, Semrad A, Yang AD, Martinez SR.

Rare Tumors. 2013 May 2;5(1):e12. doi: 10.4081/rt.2013.e12. Print 2013 Feb 11.


Assessing rural-urban disparities in the use of sentinel lymph node biopsy for melanoma.

Shah DR, Yang AD, Maverakis E, Martinez SR.

J Surg Res. 2013 Oct;184(2):1157-60. doi: 10.1016/j.jss.2013.04.091. Epub 2013 Jun 6.


Influence of physician specialty on treatment recommendations in the multidisciplinary management of soft tissue sarcoma of the extremities.

Wasif N, Smith CA, Tamurian RM, Christensen SD, Monjazeb AM, Martinez SR, Canter RJ.

JAMA Surg. 2013 Jul;148(7):632-9. doi: 10.1001/jamasurg.2013.113.


Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model.

Martinez SR, Shah DR, Yang AD, Canter RJ, Maverakis E.

ISRN Dermatol. 2013;2013:315609. doi: 10.1155/2013/315609. Epub 2013 Jan 10.


Negligible effect of perioperative epidural analgesia among patients undergoing elective gastric and pancreatic resections.

Shah DR, Brown E, Russo JE, Li CS, Martinez SR, Coates JM, Bold RJ, Canter RJ.

J Gastrointest Surg. 2013 Apr;17(4):660-7. doi: 10.1007/s11605-013-2142-4. Epub 2013 Jan 24.


Nomograms to predict risk of in-hospital and post-discharge venous thromboembolism after abdominal and thoracic surgery: an American College of Surgeons National Surgical Quality Improvement Program analysis.

Shah DR, Wang H, Bold RJ, Yang X, Martinez SR, Yang AD, Khatri VP, Wisner DH, Canter RJ.

J Surg Res. 2013 Jul;183(1):462-71. doi: 10.1016/j.jss.2012.12.016. Epub 2013 Jan 2.


Combined analysis of phase III trials evaluating [⁹⁹mTc]tilmanocept and vital blue dye for identification of sentinel lymph nodes in clinically node-negative cutaneous melanoma.

Sondak VK, King DW, Zager JS, Schneebaum S, Kim J, Leong SP, Faries MB, Averbook BJ, Martinez SR, Puleo CA, Messina JL, Christman L, Wallace AM.

Ann Surg Oncol. 2013 Feb;20(2):680-8. doi: 10.1245/s10434-012-2612-z. Epub 2012 Oct 3.


Utilization of sentinel lymph node biopsy in patients with ductal carcinoma in situ undergoing mastectomy.

Shah DR, Canter RJ, Khatri VP, Bold RJ, Yang AD, Martinez SR.

Ann Surg Oncol. 2013 Jan;20(1):24-30. doi: 10.1245/s10434-012-2539-4. Epub 2012 Sep 28.


Complete pathologic response to neoadjuvant radiotherapy is predictive of oncological outcome in patients with soft tissue sarcoma.

Shah D, Borys D, Martinez SR, Li CS, Tamurian RM, Bold RJ, Monjazeb A, Canter RJ.

Anticancer Res. 2012 Sep;32(9):3911-5.


Treatment options for metaplastic breast cancer.

Shah DR, Tseng WH, Martinez SR.

ISRN Oncol. 2012;2012:706162. doi: 10.5402/2012/706162. Epub 2012 Jun 21.


Rural-urban disparities in use of post-lumpectomy radiation.

Martinez SR, Shah DR, Tseng WH, Canter RJ, Bold RJ.

Med Oncol. 2012 Dec;29(5):3250-7. doi: 10.1007/s12032-012-0266-0. Epub 2012 Jun 9.


Geographic variation in utilization of sentinel lymph node biopsy for intermediate thickness cutaneous melanoma.

Martinez SR, Shah DR, Maverakis E, Yang AD.

J Surg Oncol. 2012 Dec;106(7):807-10. doi: 10.1002/jso.23169. Epub 2012 Jun 4.


P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapy.

Borys D, Canter RJ, Hoch B, Martinez SR, Tamurian RM, Murphy B, Bishop JW, Horvai A.

Hum Pathol. 2012 Nov;43(11):1948-54. doi: 10.1016/j.humpath.2012.02.003. Epub 2012 May 9.


Utilization of lymph node assessment in patients with ductal carcinoma in situ treated with lumpectomy.

Shah DR, Canter RJ, Khatri VP, Bold RJ, Martinez SR.

J Surg Res. 2012 Sep;177(1):e21-6. doi: 10.1016/j.jss.2012.03.015. Epub 2012 Mar 30.


The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.

Leoh LS, van Heertum B, De Rijck J, Filippova M, Rios-Colon L, Basu A, Martinez SR, Tungteakkhun SS, Filippov V, Christ F, De Leon M, Debyser Z, Casiano CA.

Mol Cancer Res. 2012 Mar;10(3):378-91. doi: 10.1158/1541-7786.MCR-11-0314. Epub 2012 Jan 24.


Urban and non-urban disparities in the use of post-mastectomy radiation for breast cancer.

Martinez SR, Tseng WH, Shah DR, Canter RJ, Bold RJ.

Med Oncol. 2012 Sep;29(3):1523-8. doi: 10.1007/s12032-011-0077-8. Epub 2011 Oct 8.


Turnover of nonessential fatty acids in cardiolipin from the rat heart.

Wahjudi PN, K Yee J, Martinez SR, Zhang J, Teitell M, Nikolaenko L, Swerdloff R, Wang C, Lee WN.

J Lipid Res. 2011 Dec;52(12):2226-33. doi: 10.1194/jlr.M015966. Epub 2011 Sep 27.


Rare tumors through the looking glass: an examination of malignant cutaneous adnexal tumors.

Martinez SR, Barr KL, Canter RJ.

Arch Dermatol. 2011 Sep;147(9):1058-62. doi: 10.1001/archdermatol.2011.229.


Predicting survival for well-differentiated liposarcoma: the importance of tumor location.

Smith CA, Martinez SR, Tseng WH, Tamurian RM, Bold RJ, Borys D, Canter RJ.

J Surg Res. 2012 Jun 1;175(1):12-7. doi: 10.1016/j.jss.2011.07.024. Epub 2011 Aug 10.


Influence of specialty and clinical experience on treatment sequencing in the multimodal management of soft tissue extremity sarcoma.

Wasif N, Tamurian RM, Christensen S, Do L, Martinez SR, Chen SL, Canter RJ.

Ann Surg Oncol. 2012 Feb;19(2):504-10. doi: 10.1245/s10434-011-1923-9. Epub 2011 Jul 16.


Do radiation use disparities influence survival in patients with advanced breast cancer?

Martinez SR, Tseng WH, Canter RJ, Chen AM, Chen SL, Bold RJ.

Cancer. 2012 Jan 1;118(1):196-204. doi: 10.1002/cncr.26231. Epub 2011 Jun 20.


A concise asymmetric total synthesis of (+)-brevisamide.

Herrmann AT, Martinez SR, Zakarian A.

Org Lett. 2011 Jul 15;13(14):3636-9. doi: 10.1021/ol201283n. Epub 2011 Jun 16.


Nomogram to predict risk of 30-day morbidity and mortality for patients with disseminated malignancy undergoing surgical intervention.

Tseng WH, Yang X, Wang H, Martinez SR, Chen SL, Meyers FJ, Bold RJ, Canter RJ.

Ann Surg. 2011 Aug;254(2):333-8. doi: 10.1097/SLA.0b013e31822513ed.


Outcomes for lymph node-positive cutaneous melanoma over two decades.

Martinez SR, Tseng WH, Young SE.

World J Surg. 2011 Jul;35(7):1567-72. doi: 10.1007/s00268-010-0903-8.


Surgical resident involvement is safe for common elective general surgery procedures.

Tseng WH, Jin L, Canter RJ, Martinez SR, Khatri VP, Gauvin J, Bold RJ, Wisner D, Taylor S, Chen SL.

J Am Coll Surg. 2011 Jul;213(1):19-26; discussion 26-8. doi: 10.1016/j.jamcollsurg.2011.03.014. Epub 2011 Apr 13.


Lack of survival benefit following adjuvant radiation in patients with retroperitoneal sarcoma: a SEER analysis.

Tseng WH, Martinez SR, Do L, Tamurian RM, Borys D, Canter RJ.

J Surg Res. 2011 Jun 15;168(2):e173-80. doi: 10.1016/j.jss.2011.02.004. Epub 2011 Mar 6.


Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in combination with topical imiquimod and retinoid cream.

Garcia MS, Ono Y, Martinez SR, Chen SL, Goodarzi H, Phan T, Wehrli LN, Miyamura Y, Fung MA, Maverakis E.

Melanoma Res. 2011 Jun;21(3):235-43. doi: 10.1097/CMR.0b013e328345e95e.


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