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Items: 1 to 50 of 302

1.

Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation.

Fitzpatrick AM, Bacharier LB, Guilbert TW, Jackson DJ, Szefler SJ, Beigelman A, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Zeiger RS, Mauger DT; NIH/NHLBI AsthmaNet.

J Allergy Clin Immunol Pract. 2018 Sep 26. pii: S2213-2198(18)30593-2. doi: 10.1016/j.jaip.2018.09.016. [Epub ahead of print]

PMID:
30267890
2.

Non-atopic rhinitis at age 6 is associated with subsequent development of asthma.

Carr TF, Stern DA, Halonen M, Wright AL, Martinez FD.

Clin Exp Allergy. 2018 Sep 16. doi: 10.1111/cea.13276. [Epub ahead of print]

PMID:
30220097
3.

Asthma: Upcoming Themed Issue.

Wedzicha JA, Martinez FD.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):549. doi: 10.1164/rccm.1985ed1. No abstract available.

PMID:
30168752
4.

Protective effect of breastfeeding on recurrent cough in adulthood.

Gerhart KD, Stern DA, Guerra S, Morgan WJ, Martinez FD, Wright AL.

Thorax. 2018 Sep;73(9):833-839. doi: 10.1136/thoraxjnl-2017-210841. Epub 2018 May 21.

PMID:
29786547
5.

Alternaria sensitisation at age 6 years is associated with subsequent airway hyper-responsiveness in non-asthmatics.

Hiranrattana A, Stern DA, Guerra S, Halonen M, Wright AL, Daines M, Martinez FD, Morgan WJ.

Thorax. 2018 Mar 21. pii: thoraxjnl-2017-210325. doi: 10.1136/thoraxjnl-2017-210325. [Epub ahead of print]

PMID:
29563159
6.

Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations.

Jackson DJ, Bacharier LB, Mauger DT, Boehmer S, Beigelman A, Chmiel JF, Fitzpatrick AM, Gaffin JM, Morgan WJ, Peters SP, Phipatanakul W, Sheehan WJ, Cabana MD, Holguin F, Martinez FD, Pongracic JA, Baxi SN, Benson M, Blake K, Covar R, Gentile DA, Israel E, Krishnan JA, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Long D, Ly N, Marbin J, Moy JN, Myers RE, Olin JT, Raissy HH, Robison RG, Ross K, Sorkness CA, Lemanske RF Jr; National Heart, Lung, and Blood Institute AsthmaNet.

N Engl J Med. 2018 Mar 8;378(10):891-901. doi: 10.1056/NEJMoa1710988. Epub 2018 Mar 3.

7.

Trajectories and Early Determinants of Circulating CC16 from Birth to Age 32 Years.

Zhai J, Stern DA, Sherrill DL, Spangenberg AL, Wright AL, Morgan WJ, Halonen M, Martinez FD, Guerra S.

Am J Respir Crit Care Med. 2018 Jul 15;198(2):267-270. doi: 10.1164/rccm.201712-2398LE. No abstract available.

PMID:
29485918
8.

Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.

Kothari PH, Qiu W, Croteau-Chonka DC, Martinez FD, Liu AH, Lemanske RF Jr, Ober C, Krishnan JA, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, White SR, Naureckas ET, Millstein J, Gauderman WJ, Gilliland FD, Carey VJ, Weiss ST, Raby BA; Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium.

J Allergy Clin Immunol. 2018 Jun;141(6):2282-2286.e6. doi: 10.1016/j.jaci.2017.11.057. Epub 2018 Jan 31. No abstract available.

PMID:
29374573
9.

Early life risk factors for chronic sinusitis: A longitudinal birth cohort study.

Chang EH, Stern DA, Willis AL, Guerra S, Wright AL, Martinez FD.

J Allergy Clin Immunol. 2018 Apr;141(4):1291-1297.e2. doi: 10.1016/j.jaci.2017.11.052. Epub 2018 Feb 21.

PMID:
29355680
10.

Overweight/obesity status in preschool children associates with worse asthma but robust improvement on inhaled corticosteroids.

Lang JE, Fitzpatrick AM, Mauger DT, Guilbert TW, Jackson DJ, Lemanske RF Jr, Martinez FD, Strunk RC, Zeiger RS, Phipatanakul W, Bacharier LB, Pongracic JA, Holguin F, Cabana MD, Covar RA, Raissy HH, Tang M, Szefler SJ; National Institutes of Health/National Heart, Lung and Blood Institute AsthmaNet.

J Allergy Clin Immunol. 2018 Apr;141(4):1459-1467.e2. doi: 10.1016/j.jaci.2017.09.043. Epub 2017 Dec 19.

PMID:
29273557
11.

Early Origins of Asthma. Role of Microbial Dysbiosis and Metabolic Dysfunction.

Martinez FD, Guerra S.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):573-579. doi: 10.1164/rccm.201706-1091PP. No abstract available.

PMID:
29048927
12.

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations.

Gardeux V, Berghout J, Achour I, Schissler AG, Li Q, Kenost C, Li J, Shang Y, Bosco A, Saner D, Halonen MJ, Jackson DJ, Li H, Martinez FD, Lussier YA.

J Am Med Inform Assoc. 2017 Nov 1;24(6):1116-1126. doi: 10.1093/jamia/ocx069.

13.

Reply to Bush: Low Lung Function in Young Adult Life Is Associated with Early Mortality.

Vasquez MM, Zhou M, Hu C, Martinez FD, Guerra S.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):539. doi: 10.1164/rccm.201708-1647LE. No abstract available.

PMID:
28925717
14.

After asthma: redefining airways diseases.

Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A.

Lancet. 2018 Jan 27;391(10118):350-400. doi: 10.1016/S0140-6736(17)30879-6. Epub 2017 Sep 11. Review. No abstract available.

15.

Mechanism of Particle Formation in Silver/Epoxy Nanocomposites Obtained through a Visible-Light-Assisted in Situ Synthesis.

dell'Erba IE, Martínez FD, Hoppe CE, Eliçabe GE, Ceolín M, Zucchi IA, Schroeder WF.

Langmuir. 2017 Oct 3;33(39):10248-10258. doi: 10.1021/acs.langmuir.7b01936. Epub 2017 Sep 20.

PMID:
28874051
16.

American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report.

Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, Punturieri A, Freemer MM, Wise RA.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):375-381. doi: 10.1164/rccm.201705-0973WS.

17.

Low Lung Function in Young Adult Life Is Associated with Early Mortality.

Vasquez MM, Zhou M, Hu C, Martinez FD, Guerra S.

Am J Respir Crit Care Med. 2017 May 15;195(10):1399-1401. doi: 10.1164/rccm.201608-1561LE. No abstract available.

18.

AJRCCM: 100-Year Anniversary. The Long View and the Fast Lane.

Wedzicha JA, Brochard LJ, Martinez FD, Martinez FJ, Donaldson G.

Am J Respir Crit Care Med. 2017 May 1;195(9):1081-1085. doi: 10.1164/rccm.201703-0525ED. No abstract available.

19.

AJRCCM: 100-Year Anniversary. Focus on Asthma in Children and Adults.

Martinez FD, Kraft M.

Am J Respir Crit Care Med. 2017 May 1;195(9):1085-1088. doi: 10.1164/rccm.201702-0301ED. No abstract available.

20.

Effects of Retinoids on Augmentation of Club Cell Secretory Protein.

Chen Y, Vasquez MM, Zhu L, Lizarraga RE, Krutzsch M, Einspahr J, Alberts DS, Di PYP, Martinez FD, Guerra S.

Am J Respir Crit Care Med. 2017 Oct 1;196(7):928-931. doi: 10.1164/rccm.201608-1611LE. No abstract available.

21.

Bending the Twig Does the Tree Incline: Lung Function after Lower Respiratory Tract Illness in Infancy.

Martinez FD.

Am J Respir Crit Care Med. 2017 Jan 15;195(2):154-155. doi: 10.1164/rccm.201611-2325ED. No abstract available.

22.

Association between the CDHR3 rs6967330 risk allele and chronic rhinosinusitis.

Chang EH, Willis AL, McCrary HC, Noutsios GT, Le CH, Chiu AG, Mansfield CJ, Reed DR, Brooks SG, Adappa ND, Palmer JN, Cohen NG, Stern DA, Guerra S, Martinez FD.

J Allergy Clin Immunol. 2017 Jun;139(6):1990-1992.e2. doi: 10.1016/j.jaci.2016.10.027. Epub 2016 Dec 3. No abstract available.

23.

Self-Reported Stressful Life Events During Adolescence and Subsequent Asthma: A Longitudinal Study.

Oren E, Gerald L, Stern DA, Martinez FD, Wright AL.

J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2):427-434.e2. doi: 10.1016/j.jaip.2016.09.019. Epub 2016 Nov 1.

24.

Response to García-Nieto et al. Comments on Beamer et al. Association of Children's Urinary CC16 Levels with Arsenic Concentrations in Multiple Environmental Media. Int. J. Environ. Res. Public Health 2016, 13, 521.

Beamer PI, Klimecki WT, Loh M, Van Horne YO, Sugeng AJ, Lothrop N, Billheimer D, Guerra S, Lantz RC, Canales RA, Martinez FD.

Int J Environ Res Public Health. 2016 Oct 4;13(10). pii: E978.

25.

Individualized therapy for persistent asthma in young children.

Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ; NIH/NHLBI AsthmaNet.

J Allergy Clin Immunol. 2016 Dec;138(6):1608-1618.e12. doi: 10.1016/j.jaci.2016.09.028. Epub 2016 Oct 21.

26.

A Distinct Low Lung Function Trajectory from Childhood to the Fourth Decade of Life.

Berry CE, Billheimer D, Jenkins IC, Lu ZJ, Stern DA, Gerald LB, Carr TF, Guerra S, Morgan WJ, Wright AL, Martinez FD.

Am J Respir Crit Care Med. 2016 Sep 1;194(5):607-12. doi: 10.1164/rccm.201604-0753OC.

27.

Early-Life Origins of Chronic Obstructive Pulmonary Disease.

Martinez FD.

N Engl J Med. 2016 Sep 1;375(9):871-8. doi: 10.1056/NEJMra1603287. Review. No abstract available.

PMID:
27579637
28.

Prevalence of Asthma in School Children on the Arizona-Sonora Border.

Carr TF, Beamer PI, Rothers J, Stern DA, Gerald LB, Rosales CB, Van Horne YO, Pivniouk ON, Vercelli D, Halonen M, Gameros M, Martinez FD, Wright AL.

J Allergy Clin Immunol Pract. 2017 Jan - Feb;5(1):114-120.e2. doi: 10.1016/j.jaip.2016.07.001. Epub 2016 Aug 17.

29.

Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.

Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W; NIH/NHLBI AsthmaNet.

N Engl J Med. 2016 Aug 18;375(7):619-30. doi: 10.1056/NEJMoa1515990.

30.

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.

Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, Martinez FD, von Mutius E, Vercelli D, Ober C, Sperling AI.

N Engl J Med. 2016 Aug 4;375(5):411-421. doi: 10.1056/NEJMoa1508749.

31.

Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control.

Croteau-Chonka DC, Qiu W, Martinez FD, Strunk RC, Lemanske RF Jr, Liu AH, Gilliland FD, Millstein J, Gauderman WJ, Ober C, Krishnan JA, White SR, Naureckas ET, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, Carey VJ, Weiss ST, Raby BA; Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium.

Am J Respir Crit Care Med. 2017 Jan 15;195(2):179-188. doi: 10.1164/rccm.201601-0107OC.

32.

Association of Children's Urinary CC16 Levels with Arsenic Concentrations in Multiple Environmental Media.

Beamer PI, Klimecki WT, Loh M, Van Horne YO, Sugeng AJ, Lothrop N, Billheimer D, Guerra S, Lantz RC, Canales RA, Martinez FD.

Int J Environ Res Public Health. 2016 May 23;13(5). pii: E521. doi: 10.3390/ijerph13050521.

33.

Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children--Reply.

Bacharier LB, Guilbert TW, Martinez FD.

JAMA. 2016 May 17;315(19):2122-3. doi: 10.1001/jama.2016.0921. No abstract available.

PMID:
27187309
34.

The dilemma of systemic steroids in preschool children with recurrent wheezing exacerbations.

Deshpande DR, Martinez FD.

Pediatr Pulmonol. 2016 Aug;51(8):775-7. doi: 10.1002/ppul.23465. Epub 2016 May 9. No abstract available.

PMID:
27158816
35.

Amish and Hutterite Environmental Farm Products Have Opposite Effects on Experimental Models of Asthma.

Gozdz J, Holbreich M, Metwali N, Thorne PS, Sperling AI, Martinez FD, Ober C, von Mutius E, Vercelli D.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S99. doi: 10.1513/AnnalsATS.201509-581MG. No abstract available.

36.

Beyond the Paradigm of Asthma as an Inflammatory Disease. A Summary of the 2015 Aspen Lung Conference.

Martinez FD.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S91-4. doi: 10.1513/AnnalsATS.201510-677MG. Review. No abstract available.

PMID:
27027960
37.

Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma.

Yan X, Chu JH, Gomez J, Koenigs M, Holm C, He X, Perez MF, Zhao H, Mane S, Martinez FD, Ober C, Nicolae DL, Barnes KC, London SJ, Gilliland F, Weiss ST, Raby BA, Cohn L, Chupp GL.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S104-5. doi: 10.1513/AnnalsATS.201510-681MG.

38.

Safety of Fluticasone plus Salmeterol in Asthma--Reassuring Data, but No Final Answer.

Martinez FD.

N Engl J Med. 2016 May 12;374(19):1887-8. doi: 10.1056/NEJMe1601040. Epub 2016 Mar 6. No abstract available.

PMID:
26946980
39.

Inconclusive Results of Randomized Trials of Prenatal Vitamin D for Asthma Prevention in Offspring: Curbing the Enthusiasm.

von Mutius E, Martinez FD.

JAMA. 2016 Jan 26;315(4):347-8. doi: 10.1001/jama.2015.18963. No abstract available.

PMID:
26813205
40.

Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial.

Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD.

JAMA. 2015 Nov 17;314(19):2034-2044. doi: 10.1001/jama.2015.13896. Erratum in: JAMA. 2016 Jan 26;315(4):419. JAMA. 2016 Jan 12;315(2):204.

41.

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs.

Li H, Pouladi N, Achour I, Gardeux V, Li J, Li Q, Zhang HH, Martinez FD, 'Skip' Garcia JGN, Lussier YA.

J Biomed Inform. 2015 Dec;58:226-234. doi: 10.1016/j.jbi.2015.10.010. Epub 2015 Oct 30.

42.

Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation.

Croteau-Chonka DC, Rogers AJ, Raj T, McGeachie MJ, Qiu W, Ziniti JP, Stubbs BJ, Liang L, Martinez FD, Strunk RC, Lemanske RF Jr, Liu AH, Stranger BE, Carey VJ, Raby BA.

PLoS One. 2015 Oct 16;10(10):e0140758. doi: 10.1371/journal.pone.0140758. eCollection 2015. Review.

43.

Spatial clusters of child lower respiratory illnesses associated with community-level risk factors.

Beamer PI, Lothrop N, Lu Z, Ascher R, Ernst K, Stern DA, Billheimer D, Wright AL, Martinez FD.

Pediatr Pulmonol. 2016 Jun;51(6):633-42. doi: 10.1002/ppul.23332. Epub 2015 Oct 5.

44.

The metabolomics of asthma control: a promising link between genetics and disease.

McGeachie MJ, Dahlin A, Qiu W, Croteau-Chonka DC, Savage J, Wu AC, Wan ES, Sordillo JE, Al-Garawi A, Martinez FD, Strunk RC, Lemanske RF Jr, Liu AH, Raby BA, Weiss S, Clish CB, Lasky-Su JA.

Immun Inflamm Dis. 2015 Sep;3(3):224-38. doi: 10.1002/iid3.61. Epub 2015 May 7.

45.

Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study.

Guerra S, Halonen M, Vasquez MM, Spangenberg A, Stern DA, Morgan WJ, Wright AL, Lavi I, Tarès L, Carsin AE, Dobaño C, Barreiro E, Zock JP, Martínez-Moratalla J, Urrutia I, Sunyer J, Keidel D, Imboden M, Probst-Hensch N, Hallberg J, Melén E, Wickman M, Bousquet J, Belgrave DC, Simpson A, Custovic A, Antó JM, Martinez FD.

Lancet Respir Med. 2015 Aug;3(8):613-20. doi: 10.1016/S2213-2600(15)00196-4. Epub 2015 Jul 6.

46.

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.

Lange P, Celli B, Agustí A, Boje Jensen G, Divo M, Faner R, Guerra S, Marott JL, Martinez FD, Martinez-Camblor P, Meek P, Owen CA, Petersen H, Pinto-Plata V, Schnohr P, Sood A, Soriano JB, Tesfaigzi Y, Vestbo J.

N Engl J Med. 2015 Jul 9;373(2):111-22. doi: 10.1056/NEJMoa1411532.

47.

CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies.

McGeachie MJ, Wu AC, Tse SM, Clemmer GL, Sordillo J, Himes BE, Lasky-Su J, Chase RP, Martinez FD, Weeke P, Shaffer CM, Xu H, Denny JC, Roden DM, Panettieri RA Jr, Raby BA, Weiss ST, Tantisira KG.

J Allergy Clin Immunol. 2015 Dec;136(6):1503-1510. doi: 10.1016/j.jaci.2015.04.039. Epub 2015 Jun 12.

48.

Stress and Bronchodilator Response in Children with Asthma.

Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, Colón-Semidey A, Alvarez M, Acosta-Pérez E, Spear ML, Martinez FD, Avila L, Weiss ST, Soto-Quiros M, Ober C, Nicolae DL, Barnes KC, Lemanske RF Jr, Strunk RC, Liu A, London SJ, Gilliland F, Sleiman P, March M, Hakonarson H, Duan QL, Kolls JK, Fritz GK, Hu D, Fani N, Stevens JS, Almli LM, Burchard EG, Shin J, McQuaid EL, Ressler K, Canino G, Celedón JC.

Am J Respir Crit Care Med. 2015 Jul 1;192(1):47-56. doi: 10.1164/rccm.201501-0037OC.

49.

Increased wheezing risk with diesel exposure among children of younger mothers.

Beamer PI, Lothrop N, Stern DA, Billheimer D, Wright AL, Martinez FD.

Eur Respir J. 2015 Sep;46(3):853-5. doi: 10.1183/09031936.00227214. Epub 2015 Apr 16. No abstract available.

50.

Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes.

Gardeux V, Bosco A, Li J, Halonen MJ, Jackson D, Martinez FD, Lussier YA.

J Biomed Inform. 2015 Jun;55:94-103. doi: 10.1016/j.jbi.2015.03.003. Epub 2015 Mar 19.

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