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Items: 18

1.

Synthesis of Stable Cholesteryl-Polyethylene Glycol-Peptide Conjugates with Non-Disperse Polyethylene Glycol Lengths.

Cristóbal-Lecina E, Pulido D, Martin-Malpartida P, Macias MJ, Albericio F, Royo M.

ACS Omega. 2020 Mar 6;5(10):5508-5519. doi: 10.1021/acsomega.0c00130. eCollection 2020 Mar 17.

2.

Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4.

Iglesias-Bexiga M, Palencia A, Corbi-Verge C, Martin-Malpartida P, Blanco FJ, Macias MJ, Cobos ES, Luque I.

Sci Rep. 2019 Oct 21;9(1):15076. doi: 10.1038/s41598-019-50701-3.

3.

TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-β signaling.

Guca E, Suñol D, Ruiz L, Konkol A, Cordero J, Torner C, Aragon E, Martin-Malpartida P, Riera A, Macias MJ.

Nucleic Acids Res. 2018 Sep 28;46(17):9220-9235. doi: 10.1093/nar/gky680.

4.

Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.

Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ.

Nat Commun. 2017 Dec 12;8(1):2070. doi: 10.1038/s41467-017-02054-6.

5.

Peptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3',5'difluorophenyl)-alanine.

Martín-Gago P, Rol Á, Todorovski T, Aragón E, Martin-Malpartida P, Verdaguer X, Vallès Miret M, Fernández-Carneado J, Ponsati B, Macias MJ, Riera A.

Sci Rep. 2016 Jun 7;6:27285. doi: 10.1038/srep27285.

6.

Preventing fibril formation of a protein by selective mutation.

Maisuradze GG, Medina J, Kachlishvili K, Krupa P, Mozolewska MA, Martin-Malpartida P, Maisuradze L, Macias MJ, Scheraga HA.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13549-54. doi: 10.1073/pnas.1518298112. Epub 2015 Oct 19.

7.

Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation.

Schelhorn C, Martín-Malpartida P, Suñol D, Macias MJ.

Sci Rep. 2015 Oct 12;5:14990. doi: 10.1038/srep14990.

8.

Structural determinants of Smad function in TGF-β signaling.

Macias MJ, Martin-Malpartida P, Massagué J.

Trends Biochem Sci. 2015 Jun;40(6):296-308. doi: 10.1016/j.tibs.2015.03.012. Epub 2015 Apr 29. Review.

9.

Structural basis of the activation and degradation mechanisms of the E3 ubiquitin ligase Nedd4L.

Escobedo A, Gomes T, Aragón E, Martín-Malpartida P, Ruiz L, Macias MJ.

Structure. 2014 Oct 7;22(10):1446-57. doi: 10.1016/j.str.2014.08.016.

10.

A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity.

Martín-Gago P, Ramón R, Aragón E, Fernández-Carneado J, Martin-Malpartida P, Verdaguer X, López-Ruiz P, Colás B, Cortes MA, Ponsati B, Macias MJ, Riera A.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):103-7. doi: 10.1016/j.bmcl.2013.11.065. Epub 2013 Dec 3.

PMID:
24342240
11.

Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine.

Martín-Gago P, Aragón E, Gomez-Caminals M, Fernández-Carneado J, Ramón R, Martin-Malpartida P, Verdaguer X, López-Ruiz P, Colás B, Cortes MA, Ponsati B, Macias MJ, Riera A.

Molecules. 2013 Nov 25;18(12):14564-84. doi: 10.3390/molecules181214564.

12.

Fine-tuning the π-π aromatic interactions in peptides: somatostatin analogues containing mesityl alanine.

Martín-Gago P, Gomez-Caminals M, Ramón R, Verdaguer X, Martin-Malpartida P, Aragón E, Fernández-Carneado J, Ponsati B, López-Ruiz P, Cortes MA, Colás B, Macias MJ, Riera A.

Angew Chem Int Ed Engl. 2012 Feb 20;51(8):1820-5. doi: 10.1002/anie.201106406. Epub 2011 Dec 9. No abstract available.

PMID:
22162246
13.

SSTR1- and SSTR3-selective somatostatin analogues.

Ramón R, Martín-Gago P, Verdaguer X, Macias MJ, Martin-Malpartida P, Fernández-Carneado J, Gomez-Caminals M, Ponsati B, López-Ruiz P, Cortés MA, Colás B, Riera A.

Chembiochem. 2011 Mar 7;12(4):625-32. doi: 10.1002/cbic.201000597. Epub 2011 Jan 21.

PMID:
21259412
14.

NMR structural studies on human p190-A RhoGAPFF1 revealed that domain phosphorylation by the PDGF-receptor alpha requires its previous unfolding.

Bonet R, Ruiz L, Aragón E, Martín-Malpartida P, Macias MJ.

J Mol Biol. 2009 Jun 5;389(2):230-7. doi: 10.1016/j.jmb.2009.04.035. Epub 2009 Apr 22.

PMID:
19393245
15.

Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains.

Ramirez-Espain X, Ruiz L, Martin-Malpartida P, Oschkinat H, Macias MJ.

J Mol Biol. 2007 Nov 9;373(5):1255-68. Epub 2007 Aug 29.

PMID:
17915251
16.

NMR structural studies of the ItchWW3 domain reveal that phosphorylation at T30 inhibits the interaction with PPxY-containing ligands.

Morales B, Ramirez-Espain X, Shaw AZ, Martin-Malpartida P, Yraola F, Sánchez-Tilló E, Farrera C, Celada A, Royo M, Macias MJ.

Structure. 2007 Apr;15(4):473-83.

17.

The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.

Gasch A, Wiesner S, Martin-Malpartida P, Ramirez-Espain X, Ruiz L, Macias MJ.

J Biol Chem. 2006 Jan 6;281(1):356-64. Epub 2005 Oct 27.

18.

Phosphorylation of either Ser16 or Thr30 does not disrupt the structure of the Itch E3 ubiquitin ligase third WW domain.

Shaw AZ, Martin-Malpartida P, Morales B, Yraola F, Royo M, Macias MJ.

Proteins. 2005 Aug 15;60(3):558-60. No abstract available.

PMID:
15971201

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