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Items: 36


Cell-autonomous programming of rat adipose tissue insulin signalling proteins by maternal nutrition.

Martin-Gronert MS, Fernandez-Twinn DS, Bushell M, Siddle K, Ozanne SE.

Diabetologia. 2016 Jun;59(6):1266-75. doi: 10.1007/s00125-016-3905-8. Epub 2016 Mar 10.


5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats.

Martin-Gronert MS, Stocker CJ, Wargent ET, Cripps RL, Garfield AS, Jovanovic Z, D'Agostino G, Yeo GS, Cawthorne MA, Arch JR, Heisler LK, Ozanne SE.

Dis Model Mech. 2016 Apr;9(4):401-12. doi: 10.1242/dmm.023903. Epub 2016 Jan 14.


Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth.

Tarry-Adkins JL, Fernandez-Twinn DS, Hargreaves IP, Neergheen V, Aiken CE, Martin-Gronert MS, McConnell JM, Ozanne SE.

Am J Clin Nutr. 2016 Feb;103(2):579-88. doi: 10.3945/ajcn.115.119834. Epub 2015 Dec 30.


Nutritional programming of coenzyme Q: potential for prevention and intervention?

Tarry-Adkins JL, Fernandez-Twinn DS, Chen JH, Hargreaves IP, Martin-Gronert MS, McConnell JM, Ozanne SE.

FASEB J. 2014 Dec;28(12):5398-405. doi: 10.1096/fj.14-259473. Epub 2014 Aug 29.


Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity.

Alfaradhi MZ, Fernandez-Twinn DS, Martin-Gronert MS, Musial B, Fowden A, Ozanne SE.

Am J Physiol Regul Integr Comp Physiol. 2014 Jul 1;307(1):R26-34. doi: 10.1152/ajpregu.00049.2014. Epub 2014 Apr 30.


Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms.

Fernandez-Twinn DS, Alfaradhi MZ, Martin-Gronert MS, Duque-Guimaraes DE, Piekarz A, Ferland-McCollough D, Bushell M, Ozanne SE.

Mol Metab. 2014 Jan 20;3(3):325-33. doi: 10.1016/j.molmet.2014.01.007. eCollection 2014 Jun.


Differential effects of exposure to maternal obesity or maternal weight loss during the periconceptional period in the sheep on insulin signalling molecules in skeletal muscle of the offspring at 4 months of age.

Nicholas LM, Morrison JL, Rattanatray L, Ozanne SE, Kleemann DO, Walker SK, MacLaughlin SM, Zhang S, Martin-Gronert MS, McMillen IC.

PLoS One. 2013 Dec 26;8(12):e84594. doi: 10.1371/journal.pone.0084594. eCollection 2013.


Coenzyme Q10 prevents accelerated cardiac aging in a rat model of poor maternal nutrition and accelerated postnatal growth.

Tarry-Adkins JL, Blackmore HL, Martin-Gronert MS, Fernandez-Twinn DS, McConnell JM, Hargreaves IP, Giussani DA, Ozanne SE.

Mol Metab. 2013 Sep 27;2(4):480-90. doi: 10.1016/j.molmet.2013.09.004. eCollection 2013.


Early life programming of obesity.

Martin-Gronert MS, Ozanne SE.

Med Wieku Rozwoj. 2013 Jan-Mar;17(1):7-12. Review.


Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring.

Nicholas LM, Rattanatray L, MacLaughlin SM, Ozanne SE, Kleemann DO, Walker SK, Morrison JL, Zhang S, Muhlhäusler BS, Martin-Gronert MS, McMillen IC.

FASEB J. 2013 Sep;27(9):3786-96. doi: 10.1096/fj.13-227918. Epub 2013 May 31.


Effects of cortisol and dexamethasone on insulin signalling pathways in skeletal muscle of the ovine fetus during late gestation.

Jellyman JK, Martin-Gronert MS, Cripps RL, Giussani DA, Ozanne SE, Shen QW, Du M, Fowden AL, Forhead AJ.

PLoS One. 2012;7(12):e52363. doi: 10.1371/journal.pone.0052363. Epub 2012 Dec 26.


Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue.

Berends LM, Fernandez-Twinn DS, Martin-Gronert MS, Cripps RL, Ozanne SE.

Int J Obes (Lond). 2013 Aug;37(8):1051-7. doi: 10.1038/ijo.2012.196. Epub 2012 Dec 11.


Poor maternal nutrition followed by accelerated postnatal growth leads to alterations in DNA damage and repair, oxidative and nitrosative stress, and oxidative defense capacity in rat heart.

Tarry-Adkins JL, Martin-Gronert MS, Fernandez-Twinn DS, Hargreaves I, Alfaradhi MZ, Land JM, Aiken CE, Ozanne SE.

FASEB J. 2013 Jan;27(1):379-90. doi: 10.1096/fj.12-218685. Epub 2012 Sep 27.


Analysis of the rat hypothalamus proteome by data-independent label-free LC-MS/MS.

Stelzhammer V, Amess B, Martins-de-Souza D, Levin Y, Ozanne SE, Martin-Gronert MS, Urday S, Bahn S, Guest PC.

Proteomics. 2012 Nov;12(22):3386-92. doi: 10.1002/pmic.201100642. Epub 2012 Oct 19.


Metabolic programming of insulin action and secretion.

Martin-Gronert MS, Ozanne SE.

Diabetes Obes Metab. 2012 Oct;14 Suppl 3:29-39. doi: 10.1111/j.1463-1326.2012.01653.x. Review.


Mechanisms underlying the developmental origins of disease.

Martin-Gronert MS, Ozanne SE.

Rev Endocr Metab Disord. 2012 Jun;13(2):85-92. doi: 10.1007/s11154-012-9210-z. Review.


Leanness in postnatally nutritionally programmed rats is associated with increased sensitivity to leptin and a melanocortin receptor agonist and decreased sensitivity to neuropeptide Y.

Stocker CJ, Wargent ET, Martin-Gronert MS, Cripps RL, O'Dowd JF, Zaibi MS, Cottrell EC, Mercer JG, Duncan JS, Cawthorne MA, Ozanne SE, Arch JR.

Int J Obes (Lond). 2012 Aug;36(8):1040-6. doi: 10.1038/ijo.2011.226. Epub 2011 Nov 29.


Leptin-independent programming of adult body weight and adiposity in mice.

Cottrell EC, Martin-Gronert MS, Fernandez-Twinn DS, Luan J, Berends LM, Ozanne SE.

Endocrinology. 2011 Feb;152(2):476-82. doi: 10.1210/en.2010-0911. Epub 2011 Jan 5.


Prenatal hypoxia independent of undernutrition promotes molecular markers of insulin resistance in adult offspring.

Camm EJ, Martin-Gronert MS, Wright NL, Hansell JA, Ozanne SE, Giussani DA.

FASEB J. 2011 Jan;25(1):420-7. doi: 10.1096/fj.10-158188. Epub 2010 Oct 5.


Altered hepatic insulin signalling in male offspring of obese mice.

Martin-Gronert MS, Fernandez-Twinn DS, Poston L, Ozanne SE.

J Dev Orig Health Dis. 2010 Jun;1(3):184-91. doi: 10.1017/S2040174410000231.


Poor early growth and excessive adult calorie intake independently and additively affect mitogenic signaling and increase mammary tumor susceptibility.

Fernandez-Twinn DS, Ekizoglou S, Martin-Gronert MS, Tarry-Adkins J, Wayman AP, Warner MJ, Luan JA, Gusterson BA, Ozanne SE.

Carcinogenesis. 2010 Oct;31(10):1873-81. doi: 10.1093/carcin/bgq095. Epub 2010 May 11.


Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice.

Oben JA, Mouralidarane A, Samuelsson AM, Matthews PJ, Morgan ML, McKee C, Soeda J, Fernandez-Twinn DS, Martin-Gronert MS, Ozanne SE, Sigala B, Novelli M, Poston L, Taylor PD.

J Hepatol. 2010 Jun;52(6):913-20. doi: 10.1016/j.jhep.2009.12.042. Epub 2010 Apr 1.


Mechanisms linking suboptimal early nutrition and increased risk of type 2 diabetes and obesity.

Martin-Gronert MS, Ozanne SE.

J Nutr. 2010 Mar;140(3):662-6. doi: 10.3945/jn.109.111237. Epub 2010 Jan 27.


Altered skeletal muscle insulin signaling and mitochondrial complex II-III linked activity in adult offspring of obese mice.

Shelley P, Martin-Gronert MS, Rowlerson A, Poston L, Heales SJ, Hargreaves IP, McConnell JM, Ozanne SE, Fernandez-Twinn DS.

Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R675-81. doi: 10.1152/ajpregu.00146.2009. Epub 2009 Jun 17.


Maternal protein restriction affects postnatal growth and the expression of key proteins involved in lifespan regulation in mice.

Chen JH, Martin-Gronert MS, Tarry-Adkins J, Ozanne SE.

PLoS One. 2009;4(3):e4950. doi: 10.1371/journal.pone.0004950. Epub 2009 Mar 24.


Programming of hypothalamic neuropeptide gene expression in rats by maternal dietary protein content during pregnancy and lactation.

Cripps RL, Martin-Gronert MS, Archer ZA, Hales CN, Mercer JG, Ozanne SE.

Clin Sci (Lond). 2009 Jun 15;117(2):85-93. doi: 10.1042/CS20080393.


Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.

Jensen CB, Martin-Gronert MS, Storgaard H, Madsbad S, Vaag A, Ozanne SE.

PLoS One. 2008;3(11):e3738. doi: 10.1371/journal.pone.0003738. Epub 2008 Nov 17.


The effect of maternal body condition score before and during pregnancy on the glucose tolerance of adult sheep offspring.

Cripps RL, Green LR, Thompson J, Martin-Gronert MS, Monk M, Sheldon IM, Hanson MA, Hales CN, Ozanne SE.

Reprod Sci. 2008 May;15(5):448-56. doi: 10.1177/1933719107312161. Epub 2008 Mar 10.


Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats.

Tarry-Adkins JL, Martin-Gronert MS, Chen JH, Cripps RL, Ozanne SE.

FASEB J. 2008 Jun;22(6):2037-44. doi: 10.1096/fj.07-099523. Epub 2008 Jan 29.


Maternal protein restriction leads to early life alterations in the expression of key molecules involved in the aging process in rat offspring.

Martin-Gronert MS, Tarry-Adkins JL, Cripps RL, Chen JH, Ozanne SE.

Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R494-500. Epub 2007 Dec 19.


Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expression.

Tarry-Adkins JL, Joles JA, Chen JH, Martin-Gronert MS, van der Giezen DM, Goldschmeding R, Hales CN, Ozanne SE.

Am J Physiol Regul Integr Comp Physiol. 2007 Sep;293(3):R1259-66. Epub 2007 Jun 20.


Experimental IUGR and later diabetes.

Martin-Gronert MS, Ozanne SE.

J Intern Med. 2007 May;261(5):437-52. Review.


Decreased protein levels of key insulin signalling molecules in adipose tissue from young men with a low birthweight: potential link to increased risk of diabetes?

Ozanne SE, Jensen CB, Tingey KJ, Martin-Gronert MS, Grunnet L, Brons C, Storgaard H, Vaag AA.

Diabetologia. 2006 Dec;49(12):2993-9. Epub 2006 Oct 25.


Maternal nutrition during pregnancy and health of the offspring.

Martin-Gronert MS, Ozanne SE.

Biochem Soc Trans. 2006 Nov;34(Pt 5):779-82.


Programming of appetite and type 2 diabetes.

Martin-Gronert MS, Ozanne SE.

Early Hum Dev. 2005 Dec;81(12):981-8. Epub 2005 Oct 27. Review.


Fetal and perinatal programming of appetite.

Cripps RL, Martin-Gronert MS, Ozanne SE.

Clin Sci (Lond). 2005 Jul;109(1):1-11. Review.


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