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Items: 1 to 50 of 131

1.

Structural basis of α-scorpion toxin action on Nav channels.

Clairfeuille T, Cloake A, Infield DT, Llongueras JP, Arthur CP, Li ZR, Jian Y, Martin-Eauclaire MF, Bougis PE, Ciferri C, Ahern CA, Bosmans F, Hackos DH, Rohou A, Payandeh J.

Science. 2019 Mar 22;363(6433). pii: eaav8573. doi: 10.1126/science.aav8573. Epub 2019 Feb 7.

PMID:
30733386
2.

Serotherapy against Voltage-Gated Sodium Channel-Targeting αToxins from Androctonus Scorpion Venom.

Martin-Eauclaire MF, Adi-Bessalem S, Hammoudi-Triki D, Laraba-Djebari F, Bougis PE.

Toxins (Basel). 2019 Jan 23;11(2). pii: E63. doi: 10.3390/toxins11020063. Review.

3.

The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension.

Martin-Eauclaire MF, Salvatierra J, Mansuelle P, Bosmans F, Bougis PE.

FEBS Lett. 2018 Aug;592(15):2668. doi: 10.1002/1873-3468.13185. Epub 2018 Aug 3. No abstract available.

4.

Evaluation of neuroprotective effects of insulin on immuno-inflammatory and systemic disorders induced by kaliotoxin, a Kv1.3 channel blocker.

Taibi-Djennah Z, Martin-Eauclaire MF, Laraba-Djebari F.

Inflamm Res. 2018 Oct;67(10):863-877. doi: 10.1007/s00011-018-1177-0. Epub 2018 Aug 6.

PMID:
30083976
5.

Ts1 from the Brazilian scorpion Tityus serrulatus: A half-century of studies on a multifunctional beta like-toxin.

Martin-Eauclaire MF, Bougis PE, de Lima ME.

Toxicon. 2018 Sep 15;152:106-120. doi: 10.1016/j.toxicon.2018.07.024. Epub 2018 Jul 29. Review.

PMID:
30059695
6.

Comparative analyses and implications for antivenom serotherapy of four Moroccan scorpion Buthus occitanus venoms: Subspecies tunetanus, paris, malhommei, and mardochei.

Emerich BL, De Lima ME, Martin-Eauclaire MF, Bougis PE.

Toxicon. 2018 Jul;149:26-36. doi: 10.1016/j.toxicon.2017.07.010. Epub 2017 Jul 13.

7.

The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension.

Martin-Eauclaire MF, Salvatierra J, Mansuelle P, Bosmans F, Bougis PE.

FEBS Lett. 2016 Sep;590(18):3221-32. doi: 10.1002/1873-3468.12357. Epub 2016 Sep 1. Erratum in: FEBS Lett. 2018 Aug;592(15):2668.

8.

Involvement of Cholinergic and Adrenergic Receptors in Pathogenesis and Inflammatory Response Induced by Alpha-Neurotoxin Bot III of Scorpion Venom.

Nakib I, Martin-Eauclaire MF, Laraba-Djebari F.

Inflammation. 2016 Oct;39(5):1670-80. doi: 10.1007/s10753-016-0401-8.

PMID:
27395044
9.

Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus ().

Martin-Eauclaire MF, Pimenta AM, Bougis PE, De Lima ME.

Toxicon. 2016 Sep 1;119:253-65. doi: 10.1016/j.toxicon.2016.06.016. Epub 2016 Jun 25. Review.

PMID:
27349167
10.

Neuro-Modulation of Immuno-Endocrine Response Induced by Kaliotoxin of Androctonus Scorpion Venom.

Ladjel-Mendil A, Martin-Eauclaire MF, Laraba-Djebari F.

J Biochem Mol Toxicol. 2016 Dec;30(12):580-587. doi: 10.1002/jbt.21824. Epub 2016 Jun 7.

PMID:
27271987
11.

K(+) channel blocker-induced neuroinflammatory response and neurological disorders: immunomodulatory effects of astaxanthin.

Sifi N, Martin-Eauclaire MF, Laraba-Djebari F.

Inflamm Res. 2016 Aug;65(8):623-34. doi: 10.1007/s00011-016-0945-y. Epub 2016 Apr 6.

PMID:
27052008
12.

Involvement of Kallikrein-Kinin System on Cardiopulmonary Alterations and Inflammatory Response Induced by Purified Aah I Toxin from Scorpion Venom.

Medjadba W, Martin-Eauclaire MF, Laraba-Djebari F.

Inflammation. 2016 Feb;39(1):290-302. doi: 10.1007/s10753-015-0249-3.

PMID:
26361946
13.

β/δ-PrIT1, a highly insecticidal toxin from the venom of the Brazilian spider Phoneutria reidyi (F.O. Pickard-Cambridge, 1897).

de Oliveira LC, Campos FV, Figueiredo SG, Cordeiro MN, Adaime BR, Richardson M, Pimenta AM, Martin-Eauclaire MF, Beirão PS, De Lima ME.

Toxicon. 2015 Sep 15;104:73-82. doi: 10.1016/j.toxicon.2015.07.010. Epub 2015 Jul 26.

14.

Shal-type (Kv4.x) potassium channel pore blockers from scorpion venoms.

Bougis PE, Martin-Eauclaire MF.

Sheng Li Xue Bao. 2015 Jun 25;67(3):248-54. Review.

15.

Complement system and immunological mediators: Their involvements in the induced inflammatory process by Androctonus australis hector venom and its toxic components.

Bekkari N, Martin-Eauclaire MF, Laraba-Djebari F.

Exp Toxicol Pathol. 2015 Jul-Aug;67(7-8):389-97. doi: 10.1016/j.etp.2015.04.002. Epub 2015 Apr 24.

PMID:
25921955
16.

A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif.

Martin-Eauclaire MF, Ferracci G, Bosmans F, Bougis PE.

J Gen Physiol. 2015 Feb;145(2):155-62. doi: 10.1085/jgp.201411268.

17.

Kv4 channels underlie A-currents with highly variable inactivation time courses but homogeneous other gating properties in the nucleus tractus solitarii.

Strube C, Saliba L, Moubarak E, Penalba V, Martin-Eauclaire MF, Tell F, Clerc N.

Pflugers Arch. 2015 Apr;467(4):789-803. doi: 10.1007/s00424-014-1533-z. Epub 2014 May 29.

PMID:
24872163
18.

A first exploration of the venom of the Buthus occitanus scorpion found in southern France.

Martin-Eauclaire MF, Bosmans F, Céard B, Diochot S, Bougis PE.

Toxicon. 2014 Mar;79:55-63. doi: 10.1016/j.toxicon.2014.01.002. Epub 2014 Jan 10.

19.

Special issue on «Toxins: from threats to benefits».

Martin-Eauclaire MF, Benoit E, Marchot P, Barbier J, Molgó J, Servent D.

Toxicon. 2013 Dec 1;75:1-2. doi: 10.1016/j.toxicon.2013.08.001. Epub 2013 Aug 6. No abstract available.

PMID:
23927926
20.

The scorpion toxin Amm VIII induces pain hypersensitivity through gain-of-function of TTX-sensitive Na⁺ channels.

Abbas N, Gaudioso-Tyzra C, Bonnet C, Gabriac M, Amsalem M, Lonigro A, Padilla F, Crest M, Martin-Eauclaire MF, Delmas P.

Pain. 2013 Aug;154(8):1204-15. doi: 10.1016/j.pain.2013.03.037. Epub 2013 Apr 6.

PMID:
23685008
21.

Characterization of the first K⁺ channel blockers from the venom of the Moroccan scorpion Buthus occitanus Paris.

Martin-Eauclaire MF, Céard B, Belghazi M, Lebrun R, Bougis PE.

Toxicon. 2013 Dec 1;75:168-76. doi: 10.1016/j.toxicon.2013.03.004. Epub 2013 Mar 21.

PMID:
23523531
22.

Achieving automated scorpion venom mass fingerprinting (VMF) in the nanogram range.

Martin-Eauclaire MF, Granjeaud S, Belghazi M, Bougis PE.

Toxicon. 2013 Jul;69:211-8. doi: 10.1016/j.toxicon.2013.03.001. Epub 2013 Mar 15.

PMID:
23500507
23.

Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels.

Maffie JK, Dvoretskova E, Bougis PE, Martin-Eauclaire MF, Rudy B.

J Physiol. 2013 May 15;591(10):2419-27. doi: 10.1113/jphysiol.2012.248831. Epub 2013 Feb 25.

24.

Neuropathophysiological effect and immuno-inflammatory response induced by kaliotoxin of androctonus scorpion venom.

Ladjel-Mendil A, Martin-Eauclaire MF, Laraba-Djebari F.

Neuroimmunomodulation. 2013;20(2):99-106. doi: 10.1159/000345706. Epub 2012 Dec 28.

PMID:
23295619
25.

Potassium Channels Blockers from the Venom of Androctonus mauretanicus mauretanicus.

Martin-Eauclaire MF, Bougis PE.

J Toxicol. 2012;2012:103608. doi: 10.1155/2012/103608. Epub 2012 May 17.

26.

Diabody mixture providing full protection against experimental scorpion envenoming with crude Androctonus australis venom.

di Tommaso A, Juste MO, Martin-Eauclaire MF, Dimier-Poisson I, Billiald P, Aubrey N.

J Biol Chem. 2012 Apr 20;287(17):14149-56. doi: 10.1074/jbc.M112.348912. Epub 2012 Feb 28.

27.

Structural insights into antibody sequestering and neutralizing of Na+ channel α-type modulator from old world scorpion venom.

Fabrichny IP, Mondielli G, Conrod S, Martin-Eauclaire MF, Bourne Y, Marchot P.

J Biol Chem. 2012 Apr 20;287(17):14136-48. doi: 10.1074/jbc.M111.315382. Epub 2012 Feb 27.

28.

Ca²⁺/cAMP-sensitive covariation of I(A) and I(H) voltage dependences tunes rebound firing in dopaminergic neurons.

Amendola J, Woodhouse A, Martin-Eauclaire MF, Goaillard JM.

J Neurosci. 2012 Feb 8;32(6):2166-81. doi: 10.1523/JNEUROSCI.5297-11.2012.

29.

Immunomodulation of the inflammatory response induced by Androctonus australis hector neurotoxins: biomarker interactions.

Raouraoua-Boukari R, Sami-Merah S, Hammoudi-Triki D, Martin-Eauclaire MF, Laraba-Djebari F.

Neuroimmunomodulation. 2012;19(2):103-10. doi: 10.1159/000330241. Epub 2012 Jan 11.

PMID:
22248726
30.

Menthol pain relief through cumulative inactivation of voltage-gated sodium channels.

Gaudioso C, Hao J, Martin-Eauclaire MF, Gabriac M, Delmas P.

Pain. 2012 Feb;153(2):473-84. doi: 10.1016/j.pain.2011.11.014. Epub 2011 Dec 14.

PMID:
22172548
31.

Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors.

Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ.

J Gen Physiol. 2011 Jul;138(1):59-72. doi: 10.1085/jgp.201110614. Epub 2011 Jun 13.

32.

Characterization of three "Birtoxin-like" toxins from the Androctonus amoreuxi scorpion venom.

Abbas N, Rosso JP, Céard B, Belghazi M, Lebrun R, Bougis PE, Martin-Eauclaire MF.

Peptides. 2011 May;32(5):911-9. doi: 10.1016/j.peptides.2011.02.004. Epub 2011 Feb 16.

PMID:
21335045
33.

Involvement of endogenous opioid system in scorpion toxin-induced antinociception in mice.

Martin-Eauclaire MF, Abbas N, Sauze N, Mercier L, Berge-Lefranc JL, Condo J, Bougis PE, Guieu R.

Neurosci Lett. 2010 Sep 20;482(1):45-50. doi: 10.1016/j.neulet.2010.06.090. Epub 2010 Jul 7.

PMID:
20619318
34.

MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity.

Zhu S, Gao B, Aumelas A, del Carmen Rodríguez M, Lanz-Mendoza H, Peigneur S, Diego-Garcia E, Martin-Eauclaire MF, Tytgat J, Possani LD.

Biochim Biophys Acta. 2010 Apr;1804(4):872-83. doi: 10.1016/j.bbapap.2009.12.017. Epub 2010 Jan 4.

PMID:
20045493
35.

Design of antibody-reactive peptides from discontinuous parts of scorpion toxins.

Alvarenga L, Moreau V, Felicori L, Nguyen C, Duarte C, Chavez-Olortegui C, Molina F, Martin-Eauclaire MF, Granier C.

Vaccine. 2010 Jan 22;28(4):970-80. doi: 10.1016/j.vaccine.2009.10.135. Epub 2009 Dec 3.

PMID:
19962461
36.

Full characterization of three toxins from the Androctonus amoreuxi scorpion venom.

Abbas N, Legros C, Ceard B, Belghazi M, Hamon A, Bougis PE, Martin-Eauclaire MF.

Toxicon. 2009 Sep 15;54(4):460-70. doi: 10.1016/j.toxicon.2009.05.020. Epub 2009 May 30.

PMID:
19486908
37.

Affinity capture using chimeric membrane proteins bound to magnetic beads for rapid ligand screening by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Legros C, Guette C, Martin-Eauclaire MF, Goyffon M, Tortajada J.

Rapid Commun Mass Spectrom. 2009 Mar;23(6):745-55. doi: 10.1002/rcm.3939.

PMID:
19204930
38.

Deconstructing voltage sensor function and pharmacology in sodium channels.

Bosmans F, Martin-Eauclaire MF, Swartz KJ.

Nature. 2008 Nov 13;456(7219):202-8. doi: 10.1038/nature07473.

39.

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes.

Abbas N, Belghazi M, Abdel-Mottaleb Y, Tytgat J, Bougis PE, Martin-Eauclaire MF.

Biochem Biophys Res Commun. 2008 Nov 21;376(3):525-30. doi: 10.1016/j.bbrc.2008.09.033. Epub 2008 Sep 18.

PMID:
18804453
40.

A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels.

Abdel-Mottaleb Y, Corzo G, Martin-Eauclaire MF, Satake H, Céard B, Peigneur S, Nambaru P, Bougis PE, Possani LD, Tytgat J.

Biochem Pharmacol. 2008 Sep 15;76(6):805-15. doi: 10.1016/j.bcp.2008.07.008. Epub 2008 Jul 18.

PMID:
18687312
41.

Combination of two antibody fragments F(ab')(2)/Fab: an alternative for scorpion envenoming treatment.

Sami-Merah S, Hammoudi-Triki D, Martin-Eauclaire MF, Laraba-Djebari F.

Int Immunopharmacol. 2008 Oct;8(10):1386-94. doi: 10.1016/j.intimp.2008.05.011. Epub 2008 Jun 17.

PMID:
18687300
42.

A structural link between inactivation and block of a K+ channel.

Ader C, Schneider R, Hornig S, Velisetty P, Wilson EM, Lange A, Giller K, Ohmert I, Martin-Eauclaire MF, Trauner D, Becker S, Pongs O, Baldus M.

Nat Struct Mol Biol. 2008 Jun;15(6):605-12. doi: 10.1038/nsmb.1430. Epub 2008 May 18.

PMID:
18488040
43.

Tityus serrulatus Hypotensins: a new family of peptides from scorpion venom.

Verano-Braga T, Rocha-Resende C, Silva DM, Ianzer D, Martin-Eauclaire MF, Bougis PE, de Lima ME, Santos RA, Pimenta AM.

Biochem Biophys Res Commun. 2008 Jul 4;371(3):515-20. doi: 10.1016/j.bbrc.2008.04.104. Epub 2008 Apr 28.

PMID:
18445483
44.

New analysis of the toxic compounds from the Androctonus mauretanicus mauretanicus scorpion venom.

Oukkache N, Rosso JP, Alami M, Ghalim N, Saïle R, Hassar M, Bougis PE, Martin-Eauclaire MF.

Toxicon. 2008 Apr;51(5):835-52. doi: 10.1016/j.toxicon.2007.12.012. Epub 2007 Dec 17.

PMID:
18243273
45.

Role of Asn(2) and Glu(7) residues in the oxidative folding and on the conformation of the N-terminal loop of apamin.

Le-Nguyen D, Chiche L, Hoh F, Martin-Eauclaire MF, Dumas C, Nishi Y, Kobayashi Y, Aumelas A.

Biopolymers. 2007 Aug 5-15;86(5-6):447-62.

PMID:
17486576
46.

Toxin binding to chimeric K+ channels immobilised on a solid nitrocellulose support.

Legros C, Martin-Eauclaire MF, Pongs O, Bougis PE.

Biochem Biophys Res Commun. 2007 Feb 23;353(4):1086-90. Epub 2006 Dec 28.

PMID:
17198678
47.

Using a recombinant bispecific antibody to block Na+ -channel toxins protects against experimental scorpion envenoming.

Juste M, Martin-Eauclaire MF, Devaux C, Billiald P, Aubrey N.

Cell Mol Life Sci. 2007 Jan;64(2):206-18.

PMID:
17187174
48.

Differential effects of five 'classical' scorpion beta-toxins on rNav1.2a and DmNav1 provide clues on species-selectivity.

Bosmans F, Martin-Eauclaire MF, Tytgat J.

Toxicol Appl Pharmacol. 2007 Jan 1;218(1):45-51. Epub 2006 Oct 14.

49.

Kv4 channels sensitive to BmTX3 in rat nervous system: autoradiographic analysis of their distribution during brain ontogenesis.

Vacher H, Diochot S, Bougis PE, Martin-Eauclaire MF, Mourre C.

Eur J Neurosci. 2006 Sep;24(5):1325-40.

PMID:
16987219
50.

Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR.

Lange A, Giller K, Hornig S, Martin-Eauclaire MF, Pongs O, Becker S, Baldus M.

Nature. 2006 Apr 13;440(7086):959-62.

PMID:
16612389

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