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Items: 1 to 50 of 388

1.

Defining the relationship between arm and leg blood pressure readings: a systematic review and meta-analysis.

Sheppard JP, Albasri A, Franssen M, Fletcher B, Pealing L, Roberts N, Obeid A, Pucci M, McManus RJ, Martin U; British and Irish Hypertension Society.

J Hypertens. 2019 Apr;37(4):660-670. doi: 10.1097/HJH.0000000000001958.

PMID:
30817444
2.

GMP-compatible manufacturing of three iPS cell lines from human peripheral blood.

Haase A, Glienke W, Engels L, Göhring G, Esser R, Arseniev L, Martin U.

Stem Cell Res. 2019 Mar;35:101394. doi: 10.1016/j.scr.2019.101394. Epub 2019 Feb 11.

3.

Schedules for Self-monitoring Blood Pressure: A Systematic Review.

Hodgkinson JA, Stevens R, Grant S, Mant J, Bray EP, Hobbs FDR, Martin U, Schwartz C, McCartney D, O'Mahony R, Perera-Salazar R, Roberts N, Stevens S, Williams B, McManus RJ.

Am J Hypertens. 2019 Mar 16;32(4):350-364. doi: 10.1093/ajh/hpy185.

4.

[Social inequalities in health among the elderly population: review of indicators used in Spain].

Mosquera I, Machón M, Vergara I, Larrañaga I, Martín U; por el Grupo de Determinantes Sociales de la Salud de la Sociedad Española de Epidemiología.

Gac Sanit. 2019 Jan 18. pii: S0213-9111(18)30248-6. doi: 10.1016/j.gaceta.2018.11.002. [Epub ahead of print] Review. Spanish.

5.

Defining the relationship between arm and leg blood pressure readings: a systematic review and meta-analysis.

Sheppard JP, Albasri A, Franssen M, Fletcher B, Pealing L, Roberts N, Obeid A, Pucci M, McManus RJ, Martin U; British and Irish Hypertension Society.

J Hypertens. 2018 Dec 11. doi: 10.1097/HJH.0000000000001958. [Epub ahead of print]

PMID:
30585948
6.

Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.

Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, Held U, Witthuhn A, Haase A, Sarkadi B, Löwer J, Wolvetang EJ, Martin U, Ivics Z, Izsvák Z, Garcia-Perez JL, Faulkner GJ, Schumann GG.

Nat Commun. 2018 Dec 19;9(1):5398. doi: 10.1038/s41467-018-07917-0.

7.

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections.

Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin AR, Brinkert K, Schott JW, Haake K, Kühnel MP, Glage S, Figueiredo C, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A, Lachmann N.

Nat Commun. 2018 Nov 30;9(1):5088. doi: 10.1038/s41467-018-07570-7.

8.

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial.

Busse WW, Bleecker ER, FitzGerald JM, Ferguson GT, Barker P, Sproule S, Olsson RF, Martin UJ, Goldman M; BORA study investigators.

Lancet Respir Med. 2019 Jan;7(1):46-59. doi: 10.1016/S2213-2600(18)30406-5. Epub 2018 Nov 8. Erratum in: Lancet Respir Med. 2019 Jan;7(1):e1.

PMID:
30416083
9.

Corrigendum to "Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice" Journal of Molecular and Cellular Cardiology 122 (2018) 114-124.

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J.

J Mol Cell Cardiol. 2018 Dec;125:205. doi: 10.1016/j.yjmcc.2018.11.003. Epub 2018 Nov 7. No abstract available.

PMID:
30414408
10.

Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension.

Sheppard JP, Stevens S, Stevens R, Martin U, Mant J, Hobbs FDR, McManus RJ.

JAMA Intern Med. 2018 Dec 1;178(12):1626-1634. doi: 10.1001/jamainternmed.2018.4684.

PMID:
30383082
11.

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA.

Lipworth BJ, Collier DJ, Gon Y, Zhong N, Nishi K, Chen R, Arora S, Maes A, Siddiqui S, Reisner C, Martin UJ.

Int J Chron Obstruct Pulmon Dis. 2018 Sep 26;13:2969-2984. doi: 10.2147/COPD.S171835. eCollection 2018.

12.
13.

A randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD.

De Backer W, De Backer J, Vos W, Verlinden I, Van Holsbeke C, Clukers J, Hajian B, Siddiqui S, Jenkins M, Reisner C, Martin UJ.

Int J Chron Obstruct Pulmon Dis. 2018 Aug 30;13:2673-2684. doi: 10.2147/COPD.S171707. eCollection 2018.

14.
15.

Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice.

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J.

J Mol Cell Cardiol. 2018 Sep;122:114-124. doi: 10.1016/j.yjmcc.2018.08.011. Epub 2018 Aug 14. Erratum in: J Mol Cell Cardiol. 2018 Dec;125:205.

PMID:
30118791
16.

A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers in HYpertension program-AIM-HY INFORM trial.

Mukhtar O, Cheriyan J, Cockcroft JR, Collier D, Coulson JM, Dasgupta I, Faconti L, Glover M, Heagerty AM, Khong TK, Lip GYH, Mander AP, Marchong MN, Martin U, McDonnell BJ, McEniery CM, Padmanabhan S, Saxena M, Sever PJ, Shiel JI, Wych J, Chowienczyk PJ, Wilkinson IB.

Am Heart J. 2018 Oct;204:102-108. doi: 10.1016/j.ahj.2018.05.006. Epub 2018 May 20.

17.

Assessment of the effect of addition of 24 hours of oral tranexamic acid post-operatively to a single intraoperative intravenous dose of tranexamic acid on calculated blood loss following primary hip and knee arthroplasty (TRAC-24): a study protocol for a randomised controlled trial.

Hill J, Magill P, Dorman A, Hogg R, Eggleton A, Benson G, McFarland M, Murphy L, Gardner E, Bryce L, Martin U, Adams C, Bell J, Campbell C, Agus A, Phair G, Molloy D, Mockford B, O'Hagan S, Beverland D.

Trials. 2018 Jul 31;19(1):413. doi: 10.1186/s13063-018-2784-3.

18.

Inhaler usability of a pressurized metered dose inhaler and a soft mist inhaler in patients with COPD: A simulated-use study.

Ding B, Siddiqui S, DePietro M, Petersson G, Martin UJ.

Chron Respir Dis. 2019 Jan-Dec;16:1479972318787914. doi: 10.1177/1479972318787914. Epub 2018 Jul 17.

19.

Prospective external validation of the Predicting Out-of-OFfice Blood Pressure (PROOF-BP) strategy for triaging ambulatory monitoring in the diagnosis and management of hypertension: observational cohort study.

Sheppard JP, Martin U, Gill P, Stevens R, Hobbs FR, Mant J, Godwin M, Hanley J, McKinstry B, Myers M, Nunan D, McManus RJ; PROOF-BP investigators.

BMJ. 2018 Jun 27;361:k2478. doi: 10.1136/bmj.k2478.

20.

A gene therapeutic approach to inhibit calcium and integrin binding protein 1 ameliorates maladaptive remodelling in pressure overload.

Grund A, Szaroszyk M, Döppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Müller OJ, Bauersachs J, Heineke J.

Cardiovasc Res. 2019 Jan 1;115(1):71-82. doi: 10.1093/cvr/cvy154.

PMID:
29931050
21.

Solubilization and renaturation of biologically active human bone morphogenetic protein-4 from inclusion bodies.

Gieseler GM, Ekramzadeh K, Nölle V, Malysheva S, Kempf H, Beutel S, Zweigerdt R, Martin U, Rinas U, Scheper T, Pepelanova I.

Biotechnol Rep (Amst). 2018 Apr 4;18:e00249. doi: 10.1016/j.btre.2018.e00249. eCollection 2018 Jun.

22.

Generation of a human CDX2 knock-in reporter iPSC line (MHHi007-A-1) to model human trophoblast differentiation.

Malysheva SV, Wunderlich S, Haase A, Göhring G, Martin U, Merkert S.

Stem Cell Res. 2018 Jul;30:117-121. doi: 10.1016/j.scr.2018.05.015. Epub 2018 May 19.

23.

Randomized study of the effects of Aerochamber Plus® Flow-Vu® on the efficacy, pharmacokinetics and safety of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler in patients with chronic obstructive pulmonary disease.

Fakih F, Spangenthal S, Sigal B, Darken P, Maes A, Siddiqui S, Gillen M, Reisner C, Martin UJ.

Respir Med. 2018 May;138:74-80. doi: 10.1016/j.rmed.2018.03.033. Epub 2018 Mar 30.

24.

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems.

Pamies D, Bal-Price A, Chesné C, Coecke S, Dinnyes A, Eskes C, Grillari R, Gstraunthaler G, Hartung T, Jennings P, Leist M, Martin U, Passier R, Schwamborn JC, Stacey GN, Ellinger-Ziegelbauer H, Daneshian M.

ALTEX. 2018;35(3):353-378. doi: 10.14573/altex.1710081. Epub 2018 Apr 13.

25.

Microstructure and Deformation Response of TRIP-Steel Syntactic Foams to Quasi-Static and Dynamic Compressive Loads.

Ehinger D, Weise J, Baumeister J, Funk A, Waske A, Krüger L, Martin U.

Materials (Basel). 2018 Apr 24;11(5). pii: E656. doi: 10.3390/ma11050656.

26.

Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture.

Olmer R, Engels L, Usman A, Menke S, Malik MNH, Pessler F, Göhring G, Bornhorst D, Bolten S, Abdelilah-Seyfried S, Scheper T, Kempf H, Zweigerdt R, Martin U.

Stem Cell Reports. 2018 May 8;10(5):1657-1672. doi: 10.1016/j.stemcr.2018.03.017. Epub 2018 Apr 19.

27.

Pharmacokinetics of glycopyrronium/formoterol fumarate dihydrate delivered via metered dose inhaler using co-suspension delivery technology in patients with moderate-to-very severe COPD.

Ferguson GT, Rodriguez-Roisin R, Reisner C, Maes A, Siddiqui S, Martin UJ.

Int J Chron Obstruct Pulmon Dis. 2018 Mar 21;13:945-953. doi: 10.2147/COPD.S154988. eCollection 2018.

28.

Cardiovascular safety profile of a fixed-dose combination of glycopyrrolate and formoterol fumarate delivered via metered dose inhaler using co-suspension delivery technology.

Ferguson GT, Reisner C, Pearle J, DePetrillo P, Maes A, Martin UJ.

Pulm Pharmacol Ther. 2018 Apr;49:67-74. doi: 10.1016/j.pupt.2018.01.007. Epub 2018 Feb 4.

29.

Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.

McManus RJ, Mant J, Franssen M, Nickless A, Schwartz C, Hodgkinson J, Bradburn P, Farmer A, Grant S, Greenfield SM, Heneghan C, Jowett S, Martin U, Milner S, Monahan M, Mort S, Ogburn E, Perera-Salazar R, Shah SA, Yu LM, Tarassenko L, Hobbs FDR; TASMINH4 investigators.

Lancet. 2018 Mar 10;391(10124):949-959. doi: 10.1016/S0140-6736(18)30309-X. Epub 2018 Feb 27.

30.

Inpatient falls in older adults: a cohort study of antihypertensive prescribing pre- and post-fall.

Omer HMRB, Hodson J, Pontefract SK, Martin U.

BMC Geriatr. 2018 Feb 23;18(1):58. doi: 10.1186/s12877-018-0749-8.

31.

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms.

Iorga B, Schwanke K, Weber N, Wendland M, Greten S, Piep B, Dos Remedios CG, Martin U, Zweigerdt R, Kraft T, Brenner B.

Front Physiol. 2018 Jan 19;8:1111. doi: 10.3389/fphys.2017.01111. eCollection 2017.

32.

Human stem cells express pannexins.

Hainz N, Beckmann A, Schubert M, Haase A, Martin U, Tschernig T, Meier C.

BMC Res Notes. 2018 Jan 22;11(1):54. doi: 10.1186/s13104-018-3125-z.

33.

Therapeutic Application of Pluripotent Stem Cells: Challenges and Risks.

Martin U.

Front Med (Lausanne). 2017 Dec 14;4:229. doi: 10.3389/fmed.2017.00229. eCollection 2017. Review.

34.

[Social inequalities in health in the older population: an insight into the debate on delayed retirement age in Spain from a public health perspective].

Martín U, Domínguez-Rodríguez A, Bacigalupe A.

Gac Sanit. 2019 Jan - Feb;33(1):82-84. doi: 10.1016/j.gaceta.2017.10.010. Epub 2017 Dec 30. Spanish.

35.

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages.

Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N.

Stem Cell Reports. 2018 Jan 9;10(1):7-16. doi: 10.1016/j.stemcr.2017.11.011. Epub 2017 Dec 14.

36.

[Health and determinants of health in second generations of international immigrants: Social inequalities in health since childhood?]

González-Rábago Y, Martín U.

Gac Sanit. 2019 Mar - Apr;33(2):156-161. doi: 10.1016/j.gaceta.2017.10.007. Epub 2017 Dec 11. Spanish.

37.

Inequalities in Health Services Usage in a National Health System Scheme: The Case of a Southern Social European Region.

Morteruel M, Rodriguez-Alvarez E, Martin U, Bacigalupe A.

Nurs Res. 2018 Jan/Feb;67(1):26-34. doi: 10.1097/NNR.0000000000000256.

PMID:
29240657
38.

Gene editing & stem cells.

Harrison PT, Hoppe N, Martin U.

J Cyst Fibros. 2018 Jan;17(1):10-16. doi: 10.1016/j.jcf.2017.11.018. Epub 2017 Dec 9. Review. No abstract available.

PMID:
29233638
39.

Differential Expression of Cholinergic System Components in Human Induced Pluripotent Stem Cells, Bone Marrow-Derived Multipotent Stromal Cells, and Induced Pluripotent Stem Cell-Derived Multipotent Stromal Cells.

Weist R, Flörkemeier T, Roger Y, Franke A, Schwanke K, Zweigerdt R, Martin U, Willbold E, Hoffmann A.

Stem Cells Dev. 2018 Feb 1;27(3):166-183. doi: 10.1089/scd.2017.0162. Epub 2018 Jan 3. Erratum in: Stem Cells Dev. 2019 Mar 1;28(5):356.

PMID:
29205106
40.

Predicting Out-of-Office Blood Pressure in the Clinic for the Diagnosis of Hypertension in Primary Care: An Economic Evaluation.

Monahan M, Jowett S, Lovibond K, Gill P, Godwin M, Greenfield S, Hanley J, Hobbs FDR, Martin U, Mant J, McKinstry B, Williams B, Sheppard JP, McManus RJ; PROOF-BP investigators.

Hypertension. 2018 Feb;71(2):250-261. doi: 10.1161/HYPERTENSIONAHA.117.10244. Epub 2017 Dec 4.

PMID:
29203628
41.

Relationship of Blood Eosinophil Count to Exacerbations in Chronic Obstructive Pulmonary Disease.

Zeiger RS, Tran TN, Butler RK, Schatz M, Li Q, Khatry DB, Martin U, Kawatkar AA, Chen W.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):944-954.e5. doi: 10.1016/j.jaip.2017.10.004. Epub 2017 Nov 15.

PMID:
29153881
42.

Targeted Gene Editing in Human Pluripotent Stem Cells Using Site-Specific Nucleases.

Merkert S, Martin U.

Adv Biochem Eng Biotechnol. 2018;163:169-186. doi: 10.1007/10_2017_25. Review.

PMID:
29124278
43.

Gamma scintigraphic pulmonary deposition study of glycopyrronium/formoterol metered dose inhaler formulated using co-suspension delivery technology.

Taylor G, Warren S, Dwivedi S, Sommerville M, Mello L, Orevillo C, Maes A, Martin UJ, Usmani OS.

Eur J Pharm Sci. 2018 Jan 1;111:450-457. doi: 10.1016/j.ejps.2017.10.026. Epub 2017 Oct 18.

44.

Antisepsis of the skin before spinal surgery with povidone iodine-alcohol followed by chlorhexidine gluconate-alcohol versus povidone iodine-alcohol applied twice for the prevention of contamination of the wound by bacteria: a randomised controlled trial.

Patrick S, McDowell A, Lee A, Frau A, Martin U, Gardner E, McLorinan G, Eames N.

Bone Joint J. 2017 Oct;99-B(10):1354-1365. doi: 10.1302/0301-620X.99B10.BJJ-2017-0291.R1.

PMID:
28963158
45.

Generation of a gene-corrected isogenic control iPSC line from cystic fibrosis patient-specific iPSCs homozygous for p.Phe508del mutation mediated by TALENs and ssODN.

Merkert S, Bednarski C, Göhring G, Cathomen T, Martin U.

Stem Cell Res. 2017 Aug;23:95-97. doi: 10.1016/j.scr.2017.07.010. Epub 2017 Jul 11.

46.

Genome stability of programmed stem cell products.

Martin U.

Adv Drug Deliv Rev. 2017 Oct 1;120:108-117. doi: 10.1016/j.addr.2017.09.004. Epub 2017 Sep 13. Review.

PMID:
28917518
47.

Age-Related Anabolic Resistance of Myofibrillar Protein Synthesis Is Exacerbated in Obese Inactive Individuals.

Smeuninx B, Mckendry J, Wilson D, Martin U, Breen L.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3535-3545. doi: 10.1210/jc.2017-00869.

48.

24-h bronchodilation and inspiratory capacity improvements with glycopyrrolate/formoterol fumarate via co-suspension delivery technology in COPD.

Reisner C, Gottschlich G, Fakih F, Koser A, Krainson J, Delacruz L, Arora S, Feldman G, Pudi K, Siddiqui S, Orevillo C, Maes A, St Rose E, Martin U.

Respir Res. 2017 Aug 18;18(1):157. doi: 10.1186/s12931-017-0636-4.

49.

Baseline Symptom Score Impact on Benefits of Glycopyrrolate/Formoterol Metered Dose Inhaler in COPD.

Martinez FJ, Fabbri LM, Ferguson GT, Orevillo C, Darken P, Martin UJ, Reisner C.

Chest. 2017 Dec;152(6):1169-1178. doi: 10.1016/j.chest.2017.07.007. Epub 2017 Jul 16.

50.

Generation of non-transgenic iPS cells from human cord blood CD34+ cells under animal component-free conditions.

Haase A, Göhring G, Martin U.

Stem Cell Res. 2017 May;21:71-73. doi: 10.1016/j.scr.2017.03.022. Epub 2017 Mar 31.

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