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Items: 1 to 50 of 400

1.

Generation of a CFTR knock-in reporter cell line (MHHi006-A-1) from a human induced pluripotent stem cell line.

Engels L, Olmer R, de la Roche J, Göhring G, Ulrich S, Haller R, Martin U, Merkert S.

Stem Cell Res. 2019 Aug 20;40:101542. doi: 10.1016/j.scr.2019.101542. [Epub ahead of print]

2.

Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture.

Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N, Osten F, de la Roche J, Polten F, Christoph Wollert K, Kraft T, Fischer M, Martin U, Gruh I, Kempf H, Zweigerdt R.

Stem Cell Reports. 2019 Aug 13;13(2):366-379. doi: 10.1016/j.stemcr.2019.06.004. Epub 2019 Jul 25.

3.

Generation of a NKX2.1 knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-2).

Olmer R, Dahlmann J, Merkert S, Baus S, Göhring G, Martin U.

Stem Cell Res. 2019 Aug;39:101492. doi: 10.1016/j.scr.2019.101492. Epub 2019 Jun 28.

4.

A Randomized, Double-Blind, Double-Dummy Study of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Relative to Umeclidinium/Vilanterol Dry Powder Inhaler in COPD.

Maltais F, Ferguson GT, Feldman GJ, Deslee G, Bourdin A, Fjällbrant H, Siwek-Posłuszna A, Jenkins MA, Martin UJ.

Adv Ther. 2019 Sep;36(9):2434-2449. doi: 10.1007/s12325-019-01015-3. Epub 2019 Jul 2.

PMID:
31267366
5.

Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab.

George L, Wright A, Mistry V, Sutcliffe A, Chachi L, Haldar K, Ramsheh MY, Richardson M, van der Merwe R, Martin U, Newbold P, Brightling CE.

Int J Chron Obstruct Pulmon Dis. 2019 Jun 5;14:1177-1185. doi: 10.2147/COPD.S198302. eCollection 2019.

6.

[Erratum to: Study protocol on the effect of the economic crisis on mortality and reproductive health and health inequalities in Spain].

Pérez G, Gotsens M, Palència L, Marí-Dell'Olmo M, Domínguez-Berjón MF, Rodríguez-Sanz M, Puig V, Bartoll X, Gandarillas A, Martín U, Bacigalupe A, Díez E, Ruiz M, Esnaola S, Calvo M, Sánchez P, Luque Fernández MÁ, Borrell C.

Gac Sanit. 2019 Sep - Oct;33(5):496. doi: 10.1016/j.gaceta.2019.05.001. Epub 2019 Jun 5. Spanish. No abstract available.

7.

[Corrigendum to: Contextual indicators to assess social determinants of health and the Spanish economic recession].

Cabrera-León A, Daponte-Codina A, Mateo I, Arroyo-Borrell E, Bartoll X, Bravo MJ, Domínguez-Berjón MF, Renart G, Álvarez-Dardet C, Marí-Dell'Olmo M, Bolívar-Muñoz J, Saez M, Escribà-Agüir V, Palència L, López MJ, Saurina C, Puig V, Martín U, Gotsens M, Borrell C, Serra-Saurina L, Sordo L, Bacigalupe A, Rodríguez-Sanz M, Pérez G, Espelt A, Ruiz M, Bernal M.

Gac Sanit. 2019 Sep - Oct;33(5):497. doi: 10.1016/j.gaceta.2019.04.001. Epub 2019 May 20. Spanish. No abstract available.

8.

Benralizumab for the Prevention of COPD Exacerbations.

Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA and TERRANOVA Study Investigators; GALATHEA Study Investigators; TERRANOVA Study Investigators.

N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20.

PMID:
31112385
9.

High-Throughput Screening for Modulators of CFTR Activity Based on Genetically Engineered Cystic Fibrosis Disease-Specific iPSCs.

Merkert S, Schubert M, Olmer R, Engels L, Radetzki S, Veltman M, Scholte BJ, Zöllner J, Pedemonte N, Galietta LJV, von Kries JP, Martin U.

Stem Cell Reports. 2019 Jun 11;12(6):1389-1403. doi: 10.1016/j.stemcr.2019.04.014. Epub 2019 May 9.

10.

Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization.

Leung WH, Gay J, Martin U, Garrett TE, Horton HM, Certo MT, Blazar BR, Morgan RA, Gregory PD, Jarjour J, Astrakhan A.

JCI Insight. 2019 Apr 30;5. pii: 124430. doi: 10.1172/jci.insight.124430.

11.

Development of a methotrexate educational guide/information/monitoring booklet for inflammatory arthritis.

Martin U, O'Gradaig D, Nolan DF, Sheehy C.

Musculoskeletal Care. 2019 Jun;17(2):234-241. doi: 10.1002/msc.1398. Epub 2019 Apr 17.

PMID:
30993834
12.

Explanation in mathematical conversations: an empirical investigation.

Pease A, Aberdein A, Martin U.

Philos Trans A Math Phys Eng Sci. 2019 Mar 11;377(2140):20180159. doi: 10.1098/rsta.2018.0159.

PMID:
30966975
13.

Defining the relationship between arm and leg blood pressure readings: a systematic review and meta-analysis.

Sheppard JP, Albasri A, Franssen M, Fletcher B, Pealing L, Roberts N, Obeid A, Pucci M, McManus RJ, Martin U; British and Irish Hypertension Society.

J Hypertens. 2019 Apr;37(4):660-670. doi: 10.1097/HJH.0000000000001958.

PMID:
30817444
14.

GMP-compatible manufacturing of three iPS cell lines from human peripheral blood.

Haase A, Glienke W, Engels L, Göhring G, Esser R, Arseniev L, Martin U.

Stem Cell Res. 2019 Mar;35:101394. doi: 10.1016/j.scr.2019.101394. Epub 2019 Feb 11.

15.

Schedules for Self-monitoring Blood Pressure: A Systematic Review.

Hodgkinson JA, Stevens R, Grant S, Mant J, Bray EP, Hobbs FDR, Martin U, Schwartz C, McCartney D, O'Mahony R, Perera-Salazar R, Roberts N, Stevens S, Williams B, McManus RJ.

Am J Hypertens. 2019 Mar 16;32(4):350-364. doi: 10.1093/ajh/hpy185.

16.

[Social inequalities in health among the elderly population: review of indicators used in Spain].

Mosquera I, Machón M, Vergara I, Larrañaga I, Martín U; por el Grupo de Determinantes Sociales de la Salud de la Sociedad Española de Epidemiología.

Gac Sanit. 2019 Jan 18. pii: S0213-9111(18)30248-6. doi: 10.1016/j.gaceta.2018.11.002. [Epub ahead of print] Review. Spanish.

17.

Defining the relationship between arm and leg blood pressure readings: a systematic review and meta-analysis.

Sheppard JP, Albasri A, Franssen M, Fletcher B, Pealing L, Roberts N, Obeid A, Pucci M, McManus RJ, Martin U; British and Irish Hypertension Society.

J Hypertens. 2018 Dec 11. doi: 10.1097/HJH.0000000000001958. [Epub ahead of print]

PMID:
30585948
18.

Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.

Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, Held U, Witthuhn A, Haase A, Sarkadi B, Löwer J, Wolvetang EJ, Martin U, Ivics Z, Izsvák Z, Garcia-Perez JL, Faulkner GJ, Schumann GG.

Nat Commun. 2018 Dec 19;9(1):5398. doi: 10.1038/s41467-018-07917-0.

19.

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections.

Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin AR, Brinkert K, Schott JW, Haake K, Kühnel MP, Glage S, Figueiredo C, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A, Lachmann N.

Nat Commun. 2018 Nov 30;9(1):5088. doi: 10.1038/s41467-018-07570-7.

20.

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial.

Busse WW, Bleecker ER, FitzGerald JM, Ferguson GT, Barker P, Sproule S, Olsson RF, Martin UJ, Goldman M; BORA study investigators.

Lancet Respir Med. 2019 Jan;7(1):46-59. doi: 10.1016/S2213-2600(18)30406-5. Epub 2018 Nov 8. Erratum in: Lancet Respir Med. 2019 Jan;7(1):e1.

PMID:
30416083
21.

Corrigendum to "Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice" Journal of Molecular and Cellular Cardiology 122 (2018) 114-124.

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J.

J Mol Cell Cardiol. 2018 Dec;125:205. doi: 10.1016/j.yjmcc.2018.11.003. Epub 2018 Nov 7. No abstract available.

PMID:
30414408
22.

Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension.

Sheppard JP, Stevens S, Stevens R, Martin U, Mant J, Hobbs FDR, McManus RJ.

JAMA Intern Med. 2018 Dec 1;178(12):1626-1634. doi: 10.1001/jamainternmed.2018.4684.

PMID:
30383082
23.

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA.

Lipworth BJ, Collier DJ, Gon Y, Zhong N, Nishi K, Chen R, Arora S, Maes A, Siddiqui S, Reisner C, Martin UJ.

Int J Chron Obstruct Pulmon Dis. 2018 Sep 26;13:2969-2984. doi: 10.2147/COPD.S171835. eCollection 2018.

24.
25.

A randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD.

De Backer W, De Backer J, Vos W, Verlinden I, Van Holsbeke C, Clukers J, Hajian B, Siddiqui S, Jenkins M, Reisner C, Martin UJ.

Int J Chron Obstruct Pulmon Dis. 2018 Aug 30;13:2673-2684. doi: 10.2147/COPD.S171707. eCollection 2018.

26.
27.

Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice.

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J.

J Mol Cell Cardiol. 2018 Sep;122:114-124. doi: 10.1016/j.yjmcc.2018.08.011. Epub 2018 Aug 14. Erratum in: J Mol Cell Cardiol. 2018 Dec;125:205.

PMID:
30118791
28.

A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers in HYpertension program-AIM-HY INFORM trial.

Mukhtar O, Cheriyan J, Cockcroft JR, Collier D, Coulson JM, Dasgupta I, Faconti L, Glover M, Heagerty AM, Khong TK, Lip GYH, Mander AP, Marchong MN, Martin U, McDonnell BJ, McEniery CM, Padmanabhan S, Saxena M, Sever PJ, Shiel JI, Wych J, Chowienczyk PJ, Wilkinson IB.

Am Heart J. 2018 Oct;204:102-108. doi: 10.1016/j.ahj.2018.05.006. Epub 2018 May 20.

29.

Assessment of the effect of addition of 24 hours of oral tranexamic acid post-operatively to a single intraoperative intravenous dose of tranexamic acid on calculated blood loss following primary hip and knee arthroplasty (TRAC-24): a study protocol for a randomised controlled trial.

Hill J, Magill P, Dorman A, Hogg R, Eggleton A, Benson G, McFarland M, Murphy L, Gardner E, Bryce L, Martin U, Adams C, Bell J, Campbell C, Agus A, Phair G, Molloy D, Mockford B, O'Hagan S, Beverland D.

Trials. 2018 Jul 31;19(1):413. doi: 10.1186/s13063-018-2784-3.

30.

Inhaler usability of a pressurized metered dose inhaler and a soft mist inhaler in patients with COPD: A simulated-use study.

Ding B, Siddiqui S, DePietro M, Petersson G, Martin UJ.

Chron Respir Dis. 2019 Jan-Dec;16:1479972318787914. doi: 10.1177/1479972318787914. Epub 2018 Jul 17.

31.

Prospective external validation of the Predicting Out-of-OFfice Blood Pressure (PROOF-BP) strategy for triaging ambulatory monitoring in the diagnosis and management of hypertension: observational cohort study.

Sheppard JP, Martin U, Gill P, Stevens R, Hobbs FR, Mant J, Godwin M, Hanley J, McKinstry B, Myers M, Nunan D, McManus RJ; PROOF-BP investigators.

BMJ. 2018 Jun 27;361:k2478. doi: 10.1136/bmj.k2478. Erratum in: BMJ. 2019 Apr 4;365:l1541.

32.

A gene therapeutic approach to inhibit calcium and integrin binding protein 1 ameliorates maladaptive remodelling in pressure overload.

Grund A, Szaroszyk M, Döppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Müller OJ, Bauersachs J, Heineke J.

Cardiovasc Res. 2019 Jan 1;115(1):71-82. doi: 10.1093/cvr/cvy154.

PMID:
29931050
33.

Solubilization and renaturation of biologically active human bone morphogenetic protein-4 from inclusion bodies.

Gieseler GM, Ekramzadeh K, Nölle V, Malysheva S, Kempf H, Beutel S, Zweigerdt R, Martin U, Rinas U, Scheper T, Pepelanova I.

Biotechnol Rep (Amst). 2018 Apr 4;18:e00249. doi: 10.1016/j.btre.2018.e00249. eCollection 2018 Jun.

34.

Generation of a human CDX2 knock-in reporter iPSC line (MHHi007-A-1) to model human trophoblast differentiation.

Malysheva SV, Wunderlich S, Haase A, Göhring G, Martin U, Merkert S.

Stem Cell Res. 2018 Jul;30:117-121. doi: 10.1016/j.scr.2018.05.015. Epub 2018 May 19.

35.

Randomized study of the effects of Aerochamber Plus® Flow-Vu® on the efficacy, pharmacokinetics and safety of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler in patients with chronic obstructive pulmonary disease.

Fakih F, Spangenthal S, Sigal B, Darken P, Maes A, Siddiqui S, Gillen M, Reisner C, Martin UJ.

Respir Med. 2018 May;138:74-80. doi: 10.1016/j.rmed.2018.03.033. Epub 2018 Mar 30.

36.

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems.

Pamies D, Bal-Price A, Chesné C, Coecke S, Dinnyes A, Eskes C, Grillari R, Gstraunthaler G, Hartung T, Jennings P, Leist M, Martin U, Passier R, Schwamborn JC, Stacey GN, Ellinger-Ziegelbauer H, Daneshian M.

ALTEX. 2018;35(3):353-378. doi: 10.14573/altex.1710081. Epub 2018 Apr 13.

37.

Microstructure and Deformation Response of TRIP-Steel Syntactic Foams to Quasi-Static and Dynamic Compressive Loads.

Ehinger D, Weise J, Baumeister J, Funk A, Waske A, Krüger L, Martin U.

Materials (Basel). 2018 Apr 24;11(5). pii: E656. doi: 10.3390/ma11050656.

38.

Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture.

Olmer R, Engels L, Usman A, Menke S, Malik MNH, Pessler F, Göhring G, Bornhorst D, Bolten S, Abdelilah-Seyfried S, Scheper T, Kempf H, Zweigerdt R, Martin U.

Stem Cell Reports. 2018 May 8;10(5):1657-1672. doi: 10.1016/j.stemcr.2018.03.017. Epub 2018 Apr 19.

39.

Pharmacokinetics of glycopyrronium/formoterol fumarate dihydrate delivered via metered dose inhaler using co-suspension delivery technology in patients with moderate-to-very severe COPD.

Ferguson GT, Rodriguez-Roisin R, Reisner C, Maes A, Siddiqui S, Martin UJ.

Int J Chron Obstruct Pulmon Dis. 2018 Mar 21;13:945-953. doi: 10.2147/COPD.S154988. eCollection 2018.

40.

Cardiovascular safety profile of a fixed-dose combination of glycopyrrolate and formoterol fumarate delivered via metered dose inhaler using co-suspension delivery technology.

Ferguson GT, Reisner C, Pearle J, DePetrillo P, Maes A, Martin UJ.

Pulm Pharmacol Ther. 2018 Apr;49:67-74. doi: 10.1016/j.pupt.2018.01.007. Epub 2018 Feb 4.

41.

Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.

McManus RJ, Mant J, Franssen M, Nickless A, Schwartz C, Hodgkinson J, Bradburn P, Farmer A, Grant S, Greenfield SM, Heneghan C, Jowett S, Martin U, Milner S, Monahan M, Mort S, Ogburn E, Perera-Salazar R, Shah SA, Yu LM, Tarassenko L, Hobbs FDR; TASMINH4 investigators.

Lancet. 2018 Mar 10;391(10124):949-959. doi: 10.1016/S0140-6736(18)30309-X. Epub 2018 Feb 27.

42.

Inpatient falls in older adults: a cohort study of antihypertensive prescribing pre- and post-fall.

Omer HMRB, Hodson J, Pontefract SK, Martin U.

BMC Geriatr. 2018 Feb 23;18(1):58. doi: 10.1186/s12877-018-0749-8.

43.

Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs. Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms.

Iorga B, Schwanke K, Weber N, Wendland M, Greten S, Piep B, Dos Remedios CG, Martin U, Zweigerdt R, Kraft T, Brenner B.

Front Physiol. 2018 Jan 19;8:1111. doi: 10.3389/fphys.2017.01111. eCollection 2017.

44.

Human stem cells express pannexins.

Hainz N, Beckmann A, Schubert M, Haase A, Martin U, Tschernig T, Meier C.

BMC Res Notes. 2018 Jan 22;11(1):54. doi: 10.1186/s13104-018-3125-z.

45.

Therapeutic Application of Pluripotent Stem Cells: Challenges and Risks.

Martin U.

Front Med (Lausanne). 2017 Dec 14;4:229. doi: 10.3389/fmed.2017.00229. eCollection 2017. Review.

46.

[Social inequalities in health in the older population: an insight into the debate on delayed retirement age in Spain from a public health perspective].

Martín U, Domínguez-Rodríguez A, Bacigalupe A.

Gac Sanit. 2019 Jan - Feb;33(1):82-84. doi: 10.1016/j.gaceta.2017.10.010. Epub 2017 Dec 30. Spanish.

47.

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages.

Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N.

Stem Cell Reports. 2018 Jan 9;10(1):7-16. doi: 10.1016/j.stemcr.2017.11.011. Epub 2017 Dec 14.

48.

[Health and determinants of health in second generations of international immigrants: Social inequalities in health since childhood?]

González-Rábago Y, Martín U.

Gac Sanit. 2019 Mar - Apr;33(2):156-161. doi: 10.1016/j.gaceta.2017.10.007. Epub 2017 Dec 11. Spanish.

49.

Inequalities in Health Services Usage in a National Health System Scheme: The Case of a Southern Social European Region.

Morteruel M, Rodriguez-Alvarez E, Martin U, Bacigalupe A.

Nurs Res. 2018 Jan/Feb;67(1):26-34. doi: 10.1097/NNR.0000000000000256.

PMID:
29240657
50.

Gene editing & stem cells.

Harrison PT, Hoppe N, Martin U.

J Cyst Fibros. 2018 Jan;17(1):10-16. doi: 10.1016/j.jcf.2017.11.018. Epub 2017 Dec 9. Review. No abstract available.

PMID:
29233638

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